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Perspectives in Diabetes

Guidelines for Intervention Trials in Subjects With Newly Diagnosed Type 1 Diabetes

Carla J. Greenbaum; Leonard C. Harrison; on behalf of the Immunology of Diabetes Society

Abstracts

View articletitled, Guidelines for Intervention Trials in Subjects With Newly Diagnosed Type 1 Diabetes

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Topics: autoantibodies , c-peptide , diabetes mellitus, type 1 , insulin , outcome measures

Diabetes May 2003, Vol.52, 1059-1065. doi:https://doi.org/10.2337/diabetes.52.5.1059

Metabolism and Signal Transduction

5-Amino-Imidazole Carboxamide Riboside Increases Glucose Transport and Cell-Surface GLUT4 Content in Skeletal Muscle From Subjects With Type 2 Diabetes

Heikki A. Koistinen; Dana Galuska; Alexander V. Chibalin; Jing Yang; Juleen R. Zierath; Geoffrey D. Holman; Harriet Wallberg-Henriksson

Abstracts

View articletitled, 5-Amino-Imidazole Carboxamide Riboside Increases Glucose Transport and Cell-Surface GLUT4 Content in Skeletal Muscle From Subjects With Type 2 Diabetes

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Topics: aica ribonucleotide , ampk , diabetes mellitus, type 2 , glucose transport , insulin

Diabetes May 2003, Vol.52, 1066-1072. doi:https://doi.org/10.2337/diabetes.52.5.1066

Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells: Roles of MAPK^erk and MAPK^p38

Wo-Shing Au; Hsiang-fu Kung; Marie C. Lin

Abstracts

View articletitled, Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells: Roles of MAPKerk and MAPKp38

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Topics: insulin , mitogen-activated protein kinases , mitogen-activated protein kinase p38 , transcription, genetic , signal transduction

Diabetes May 2003, Vol.52, 1073-1080. doi:https://doi.org/10.2337/diabetes.52.5.1073

Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin

Coen H. Wiegman; Robert H.J. Bandsma; Margriet Ouwens; Fjodor H. van der Sluijs; Rick Havinga; Theo Boer; Dirk-Jan Reijngoud; Johannes A. Romijn; Folkert Kuipers

Abstracts

View articletitled, Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin

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Topics: apolipoproteins b , insulin , lipoproteins, vldl , liver , mice

Diabetes May 2003, Vol.52, 1081-1089. doi:https://doi.org/10.2337/diabetes.52.5.1081

A Role for Suppressed Thermogenesis Favoring Catch-Up Fat in the Pathophysiology of Catch-Up Growth

Raffaella Crescenzo; Sonia Samec; Vladan Antic; Francoise Rohner-Jeanrenaud; Josiane Seydoux; Jean-Pierre Montani; Abdul G. Dulloo

Abstracts

View articletitled, A Role for Suppressed Thermogenesis Favoring Catch-Up Fat in the Pathophysiology of Catch-Up Growth

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Topics: blood pressure , diet , diet, high-fat , fat-restricted diet , glucose

Diabetes May 2003, Vol.52, 1090-1097. doi:https://doi.org/10.2337/diabetes.52.5.1090

Restoration of Euglycemia and Normal Acute Insulin Response to Glucose in Obese Subjects With Type 2 Diabetes Following Bariatric Surgery

Eftihia V. Polyzogopoulou; Fotios Kalfarentzos; Apostolos G. Vagenakis; Theodore K. Alexandrides

Abstracts

View articletitled, Restoration of Euglycemia and Normal Acute Insulin Response to Glucose in Obese Subjects With Type 2 Diabetes Following Bariatric Surgery

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Topics: diabetes mellitus, type 2 , glucose , insulin , insulin sensitivity , obesity

Diabetes May 2003, Vol.52, 1098-1103. doi:https://doi.org/10.2337/diabetes.52.5.1098

Obesity Studies

Adipose Tissue Is a Major Source of Interleukin-1 Receptor Antagonist : Upregulation in Obesity and Inflammation

Cristiana E. Juge-Aubry; Emmanuel Somm; Vittorio Giusti; Agnès Pernin; Rachel Chicheportiche; Chantal Verdumo; Françoise Rohner-Jeanrenaud; Danielle Burger; Jean-Michel Dayer; Christoph A. Meier

Abstracts

View articletitled, Adipose Tissue Is a Major Source of Interleukin-1 Receptor Antagonist : Upregulation in Obesity and Inflammation

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Topics: adipose tissue , cytokine , mice , obesity , pmel17

Diabetes May 2003, Vol.52, 1104-1110. doi:https://doi.org/10.2337/diabetes.52.5.1104

Immunology and Transplantation

A New Murine Model of Islet Xenograft Rejection : Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages

Peter Schmidt; Henrik Krook; Akira Maeda; Olle Korsgren; Birgitta Benda

Abstracts

View articletitled, A New Murine Model of Islet Xenograft Rejection : Graft Destruction Is Dependent on a Major Histocompatibility–Specific Interaction Between T-Cells and Macrophages

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Topics: mice , tissue transplants , transfer technique , transplantation , transplantation, heterologous

Diabetes May 2003, Vol.52, 1111-1118. doi:https://doi.org/10.2337/diabetes.52.5.1111

Adenovirus Early Region 3 Antiapoptotic 10.4K, 14.5K, and 14.7K Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice

Melissa A. Pierce; Harold D. Chapman; Cristina M. Post; Anton Svetlanov; Shimon Efrat; Marshall Horwitz; David V. Serreze

Abstracts

View articletitled, Adenovirus Early Region 3 Antiapoptotic 10.4K, 14.5K, and 14.7K Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice

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Topics: antiapoptotic agents , genes , mice, inbred nod , mice , transgenes

Diabetes May 2003, Vol.52, 1119-1127. doi:https://doi.org/10.2337/diabetes.52.5.1119

Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

Polly J. Bingley; Ezio Bonifacio; Patricia W. Mueller; Participating Laboratories

Abstracts

View articletitled, Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

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Topics: antibodies , generalized anxiety disorder , world health organization , autoantibodies , serum

Diabetes May 2003, Vol.52, 1128-1136. doi:https://doi.org/10.2337/diabetes.52.5.1128

An Association of Autoantibody Status and Serum Cytokine Levels in Type 1 Diabetes

Pejman Hanifi-Moghaddam; Nanette C. Schloot; Simone Kappler; Jochen Seiβler; Hubert Kolb

Abstracts

View articletitled, An Association of Autoantibody Status and Serum Cytokine Levels in Type 1 Diabetes

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Topics: autoantibodies , chemokines , cytokine , diabetes mellitus, type 1 , antibodies

Diabetes May 2003, Vol.52, 1137-1142. doi:https://doi.org/10.2337/diabetes.52.5.1137

Successful Human Islet Isolation Utilizing Recombinant Collagenase

Heide Brandhorst; Daniel Brandhorst; Friederike Hesse; Dorothee Ambrosius; Mathias Brendel; Yoshiyuki Kawakami; Reinhard G. Bretzel

Abstracts

View articletitled, Successful Human Islet Isolation Utilizing Recombinant Collagenase

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Topics: collagenase , donors , enzymes , digestion

Diabetes May 2003, Vol.52, 1143-1146. doi:https://doi.org/10.2337/diabetes.52.5.1143

Islet Studies

A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line

Fiona M. Gribble; Leanne Williams; Anna K. Simpson; Frank Reimann

Abstracts

View articletitled, A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line

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Topics: bodily secretions , glucagon-like peptide 1 , glucose , sugars , fructose

Diabetes May 2003, Vol.52, 1147-1154. doi:https://doi.org/10.2337/diabetes.52.5.1147

Overexpression of PACAP in Transgenic Mouse Pancreatic β-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes

Kyohei Yamamoto; Hitoshi Hashimoto; Shuhei Tomimoto; Norihito Shintani; Jun-ichi Miyazaki; Fumi Tashiro; Hiroyuki Aihara; Takao Nammo; Ming Li; Kazuya Yamagata; Jun-ichiro Miyagawa; Yuji Matsuzawa; Yuki Kawabata; Yuji Fukuyama; Kazumi Koga; Wakaba Mori; Kazuhiro Tanaka; Toshio Matsuda; Akemichi Baba

Abstracts

View articletitled, Overexpression of PACAP in Transgenic Mouse Pancreatic β-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes

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Topics: insulin , mice , mice, transgenic , pancreas , pituitary adenylate cyclase activating polypeptide

Diabetes May 2003, Vol.52, 1155-1162. doi:https://doi.org/10.2337/diabetes.52.5.1155

Analysis of Insulin-Producing Cells During In Vitro Differentiation From Feeder-Free Embryonic Stem Cells

Yusuke Moritoh; Eiji Yamato; Yumiko Yasui; Satsuki Miyazaki; Jun-ichi Miyazaki

Abstracts

View articletitled, Analysis of Insulin-Producing Cells During In Vitro Differentiation From Feeder-Free Embryonic Stem Cells

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Topics: gene expression , insulin , embryonic stem cells , glucose

Diabetes May 2003, Vol.52, 1163-1168. doi:https://doi.org/10.2337/diabetes.52.5.1163

Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated Apoptosis

Inik Chang; Sunshin Kim; Ja Young Kim; Namjoo Cho; Yun-Hee Kim; Hun Sik Kim; Moon-Kyu Lee; Kwang-Won Kim; Myung-Shik Lee

Abstracts

View articletitled, Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated Apoptosis

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Topics: endocrine pancreas , insulinoma , tumor necrosis factors , cell death , apoptosis

Diabetes May 2003, Vol.52, 1169-1175. doi:https://doi.org/10.2337/diabetes.52.5.1169

Intra-Islet Somatostatin Regulates Glucagon Release via Type 2 Somatostatin Receptors in Rats

Kenan Cejvan; David H. Coy; Suad Efendic

Abstracts

View articletitled, Intra-Islet Somatostatin Regulates Glucagon Release via Type 2 Somatostatin Receptors in Rats

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Topics: arginine , glucagon , glucose , insulin , pancreas

Diabetes May 2003, Vol.52, 1176-1181. doi:https://doi.org/10.2337/diabetes.52.5.1176

Pathophysiology

Circulating Adiponectin Levels Are Reduced in Nonobese but Insulin-Resistant First-Degree Relatives of Type 2 Diabetic Patients

F. Pellmé; U. Smith; T. Funahashi; Y. Matsuzawa; H. Brekke; O. Wiklund; M.-R. Taskinen; P.-A. Jansson

Abstracts

View articletitled, Circulating Adiponectin Levels Are Reduced in Nonobese but Insulin-Resistant First-Degree Relatives of Type 2 Diabetic Patients

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Topics: adiponectin , insulin , proinsulin , high density lipoprotein cholesterol , insulin sensitivity

Diabetes May 2003, Vol.52, 1182-1186. doi:https://doi.org/10.2337/diabetes.52.5.1182

Deleterious Effects of Acute Treatment With a Peroxisome Proliferator–Activated Receptor-γ Activator in Myocardial Ischemia and Reperfusion in Pigs

Ya Xu; Li Lu; Clifford Greyson; Jenny Lee; Michael Gen; Koichiro Kinugawa; Carlin S. Long; Gregory G. Schwartz

Abstracts

View articletitled, Deleterious Effects of Acute Treatment With a Peroxisome Proliferator–Activated Receptor-γ Activator in Myocardial Ischemia and Reperfusion in Pigs

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Topics: ischemia , myocardium , peroxisome proliferator-activated receptors , physiologic reperfusion , reperfusion therapy

Diabetes May 2003, Vol.52, 1187-1194. doi:https://doi.org/10.2337/diabetes.52.5.1187

Sleep-Related Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes: Reduced Awakening From Sleep During Hypoglycemia

Salomon Banarer; Philip E. Cryer

Abstracts

View articletitled, Sleep-Related Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes: Reduced Awakening From Sleep During Hypoglycemia

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Topics: diabetes mellitus, type 1 , epinephrine , glucose , hypoglycemia , hypoglycemic agents

Diabetes May 2003, Vol.52, 1195-1203. doi:https://doi.org/10.2337/diabetes.52.5.1195

Complications

A Low-Iron-Available, Polyphenol-Enriched, Carbohydrate-Restricted Diet to Slow Progression of Diabetic Nephropathy

Francesco S. Facchini; Kami L. Saylor

Abstracts

View articletitled, A Low-Iron-Available, Polyphenol-Enriched, Carbohydrate-Restricted Diet to Slow Progression of Diabetic Nephropathy

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Topics: creatinine tests, serum , diabetic nephropathy , diet , iron , kidney failure, chronic

Diabetes May 2003, Vol.52, 1204-1209. doi:https://doi.org/10.2337/diabetes.52.5.1204

NCEP-Defined Metabolic Syndrome, Diabetes, and Prevalence of Coronary Heart Disease Among NHANES III Participants Age 50 Years and Older

Charles M. Alexander; Pamela B. Landsman; Steven M. Teutsch; Steven M. Haffner

Abstracts

View articletitled, NCEP-Defined Metabolic Syndrome, Diabetes, and Prevalence of Coronary Heart Disease Among NHANES III Participants Age 50 Years and Older

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Topics: metabolic syndrome x , coronary heart disease , national health and nutrition examination survey

Diabetes May 2003, Vol.52, 1210-1214. doi:https://doi.org/10.2337/diabetes.52.5.1210

Plasma Prekallikrein: A Risk Marker for Hypertension and Nephropathy in Type 1 Diabetes

Ayad A. Jaffa; Ramon Durazo-Arvizu; Deyi Zheng; Daniel T. Lackland; Sujata Srikanth; W. Timothy Garvey; Alvin H. Schmaier; the DCCT/EDIC Study Group

Abstracts

View articletitled, Plasma Prekallikrein: A Risk Marker for Hypertension and Nephropathy in Type 1 Diabetes

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Topics: dcct trial , diabetes mellitus, type 1 , edic trial , hypertension , kidney diseases

Diabetes May 2003, Vol.52, 1215-1221. doi:https://doi.org/10.2337/diabetes.52.5.1215

Maternal Diabetes In Vivo and High Glucose In Vitro Diminish GAPDH Activity in Rat Embryos

Parri Wentzel; Andreas Ejdesjö; Ulf J. Eriksson

Abstracts

View articletitled, Maternal Diabetes In Vivo and High Glucose In Vitro Diminish GAPDH Activity in Rat Embryos

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Topics: embryo , glucose , gestational diabetes , congenital abnormality , teratogenesis

Diabetes May 2003, Vol.52, 1222-1228. doi:https://doi.org/10.2337/diabetes.52.5.1222

Downregulation of Fibronectin Overexpression Reduces Basement Membrane Thickening and Vascular Lesions in Retinas of Galactose-Fed Rats

Sayon Roy; Tsuyoshi Sato; Gulabray Paryani; Richard Kao

Abstracts

View articletitled, Downregulation of Fibronectin Overexpression Reduces Basement Membrane Thickening and Vascular Lesions in Retinas of Galactose-Fed Rats

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Topics: blood capillaries , fibronectins , galactose , retina , oligonucleotides

Diabetes May 2003, Vol.52, 1229-1234. doi:https://doi.org/10.2337/diabetes.52.5.1229

Increased Expression of Ornithine Decarboxylase in Distal Tubules of Early Diabetic Rat Kidneys: Are Polyamines Paracrine Hypertrophic Factors?

Aihua Deng; Karen A. Munger; Jose M. Valdivielso; Joseph Satriano; Mark Lortie; Roland C. Blantz; Scott C. Thomson

Abstracts

View articletitled, Increased Expression of Ornithine Decarboxylase in Distal Tubules of Early Diabetic Rat Kidneys: Are Polyamines Paracrine Hypertrophic Factors?

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Topics: bromodeoxyuridine , kidney , polyamines , ornithine decarboxylase , reverse transcriptase polymerase chain reaction

Diabetes May 2003, Vol.52, 1235-1239. doi:https://doi.org/10.2337/diabetes.52.5.1235

Diabetic LDL Triggers Apoptosis in Vascular Endothelial Cells

Michaela Artwohl; Wolfgang F. Graier; Michael Roden; Martin Bischof; Angelika Freudenthaler; Werner Waldhäusl; Sabina M. Baumgartner-Parzer

Abstracts

View articletitled, Diabetic LDL Triggers Apoptosis in Vascular Endothelial Cells

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Topics: low-density lipoproteins , apoptosis

Diabetes May 2003, Vol.52, 1240-1247. doi:https://doi.org/10.2337/diabetes.52.5.1240

A Novel Role for CD36 in VLDL-Enhanced Platelet Activation

Nicola A. Englyst; Janis M. Taube; Timothy J. Aitman; Trevor P. Baglin; Christopher D. Byrne

Abstracts

View articletitled, A Novel Role for CD36 in VLDL-Enhanced Platelet Activation

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Topics: blood platelets , cd36 antigens , collagen , lipoproteins, vldl , platelet aggregation

Diabetes May 2003, Vol.52, 1248-1255. doi:https://doi.org/10.2337/diabetes.52.5.1248

High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

Narkunaraja Shanmugam; Marpadga A. Reddy; Mausumee Guha; Rama Natarajan

Abstracts

View articletitled, High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

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Topics: adhesions , chemokines , cytokine , genes , monocyte chemoattractant protein-1

Diabetes May 2003, Vol.52, 1256-1264. doi:https://doi.org/10.2337/diabetes.52.5.1256

Genetics

The Peroxisome Proliferator-Activated Receptor-γ2 Gene Polymorphism (Pro12Ala) Beneficially Influences Insulin Resistance and Its Tracking From Childhood to Adulthood: The Bogalusa Heart Study

Shengxu Li; Wei Chen; Sathanur R. Srinivasan; Eric Boerwinkle; Gerald S. Berenson

Abstracts

View articletitled, The Peroxisome Proliferator-Activated Receptor-γ2 Gene Polymorphism (Pro12Ala) Beneficially Influences Insulin Resistance and Its Tracking From Childhood to Adulthood: The Bogalusa Heart Study

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Topics: alleles , body mass index procedure , bogalusa heart study , child , genes

Diabetes May 2003, Vol.52, 1265-1269. doi:https://doi.org/10.2337/diabetes.52.5.1265

Endothelial Nitric Oxide Synthase Polymorphisms Are Associated With Type 2 Diabetes and the Insulin Resistance Syndrome

Lucilla D. Monti; Cristina Barlassina; Lorena Citterio; Elena Galluccio; Carlo Berzuini; Emanuela Setola; Gianpietro Valsecchi; Pietro Lucotti; Guido Pozza; Luisa Bernardinelli; Giorgio Casari; PierMarco Piatti

Abstracts

View articletitled, Endothelial Nitric Oxide Synthase Polymorphisms Are Associated With Type 2 Diabetes and the Insulin Resistance Syndrome

Supplementary data

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Topics: diabetes mellitus, type 2 , genotype , insulin resistance , nitric oxide synthase , polymorphism

Diabetes May 2003, Vol.52, 1270-1275. doi:https://doi.org/10.2337/diabetes.52.5.1270

Brief Genetics Reports

Genetic Variation in the Small Heterodimer Partner Gene and Young-Onset Type 2 Diabetes, Obesity, and Birth Weight in U.K. Subjects

Simon M.S. Mitchell; Michael N. Weedon; Katharine R. Owen; Beverley Shields; Beverley Wilkins-Wall; Mark Walker; Mark I. McCarthy; Timothy M. Frayling; Andrew T. Hattersley

Abstracts

View articletitled, Genetic Variation in the Small Heterodimer Partner Gene and Young-Onset Type 2 Diabetes, Obesity, and Birth Weight in U.K. Subjects

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Topics: birth weight , diabetes mellitus, type 2 , obesity , genetics , genes

Diabetes May 2003, Vol.52, 1276-1279. doi:https://doi.org/10.2337/diabetes.52.5.1276

A Common Polymorphism in the Promoter of UCP2 Contributes to the Variation in Insulin Secretion in Glucose-Tolerant Subjects

Giorgio Sesti; Marina Cardellini; Maria Adelaide Marini; Simona Frontoni; Monica D’Adamo; Silvia Del Guerra; Davide Lauro; Pierluigi De Nicolais; Paolo Sbraccia; Stefano Del Prato; Sergio Gambardella; Massimo Federici; Piero Marchetti; Renato Lauro

Abstracts

View articletitled, A Common Polymorphism in the Promoter of UCP2 Contributes to the Variation in Insulin Secretion in Glucose-Tolerant Subjects

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Topics: glucose , insulin secretion , polymorphism , insulin , genotype

Diabetes May 2003, Vol.52, 1280-1283. doi:https://doi.org/10.2337/diabetes.52.5.1280

Linkage for BMI at 3q27 Region Confirmed in an African-American Population

Amy Luke; Xiaodong Wu; Xiaofeng Zhu; Donghui Kan; Yan Su; Richard Cooper

Abstracts

View articletitled, Linkage for BMI at 3q27 Region Confirmed in an African-American Population

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Topics: body mass index procedure , genotype determination , obesity , genetic linkage analysis

Diabetes May 2003, Vol.52, 1284-1287. doi:https://doi.org/10.2337/diabetes.52.5.1284

Contribution of Variants in the Small Heterodimer Partner Gene to Birthweight, Adiposity, and Insulin Levels: Mutational Analysis and Association Studies in Multiple Populations

Chiao-Chien Connie Hung; I. Sadaf Farooqi; Ken Ong; Jian’an Luan; Julia M. Keogh; Marcus Pembrey; Giles S.H. Yeo; David Dunger; Nicholas J. Wareham; Stephen O’ Rahilly

Abstracts

View articletitled, Contribution of Variants in the Small Heterodimer Partner Gene to Birthweight, Adiposity, and Insulin Levels: Mutational Analysis and Association Studies in Multiple Populations

Supplementary data

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Topics: birth weight , insulin , obesity , alspac study , polymorphism

Diabetes May 2003, Vol.52, 1288-1291. doi:https://doi.org/10.2337/diabetes.52.5.1288

Genetic Variation in the Human Winged Helix/Forkhead Transcription Factor Gene FOXC2 in Pima Indians

Peter Kovacs; Angela Lehn-Stefan; Michael Stumvoll; Clifton Bogardus; Leslie J. Baier

Abstracts

View articletitled, Genetic Variation in the Human Winged Helix/Forkhead Transcription Factor Gene FOXC2 in Pima Indians

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Topics: foxc2 gene , genes , glucose , helix (snails) , insulin

Diabetes May 2003, Vol.52, 1292-1295. doi:https://doi.org/10.2337/diabetes.52.5.1292

Association of Polymorphisms in GPR10, the Gene Encoding the Prolactin-Releasing Peptide Receptor With Blood Pressure, but not Obesity, in a U.K. Caucasian Population

Sumit Bhattacharyya; Jian’an Luan; Benjamin Challis; Catherine Schmitz; Paul Clarkson; Paul W. Franks; Rita Middelberg; Julia Keogh; I. Sadaf Farooqi; Carl Montague; John Brennand; Nicholas J. Wareham; Stephen O’Rahilly

Abstracts

View articletitled, Association of Polymorphisms in GPR10, the Gene Encoding the Prolactin-Releasing Peptide Receptor With Blood Pressure, but not Obesity, in a U.K. Caucasian Population

Supplementary data

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Topics: blood pressure , genes , obesity , polymorphism , prolactin

Diabetes May 2003, Vol.52, 1296-1299. doi:https://doi.org/10.2337/diabetes.52.5.1296

Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility

Christopher J. Groves; Steven Wiltshire; Damian Smedley; Katherine R. Owen; Timothy M. Frayling; Mark Walker; Graham A. Hitman; Jonathan C. Levy; Stephen O’Rahilly; Stephan Menzel; Andrew T. Hattersley; Mark I. McCarthy

Abstracts

View articletitled, Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility

Supplementary data

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Topics: diabetes mellitus, type 2 , genes , genotype determination , haplotypes , insulinase

Diabetes May 2003, Vol.52, 1300-1305. doi:https://doi.org/10.2337/diabetes.52.5.1300

Errata

Extract

View articletitled, Errata

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Topics: alleles , calpain 10 , diabetes mellitus, type 2 , finland , gene frequency

Diabetes May 2003, Vol.52, 1306-1307. doi:https://doi.org/10.2337/diabetes.52.5.1306

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