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Issues
1 May 2003
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Guidelines for Intervention Trials in Subjects With Newly Diagnosed Type 1 Diabetes
Diabetes May 2003, Vol.52, 1059-1065. doi:https://doi.org/10.2337/diabetes.52.5.1059
Metabolism and Signal Transduction
5-Amino-Imidazole Carboxamide Riboside Increases Glucose Transport and Cell-Surface GLUT4 Content in Skeletal Muscle From Subjects With Type 2 Diabetes
Heikki A. Koistinen; Dana Galuska; Alexander V. Chibalin; Jing Yang; Juleen R. Zierath; Geoffrey D. Holman; Harriet Wallberg-Henriksson
Diabetes May 2003, Vol.52, 1066-1072. doi:https://doi.org/10.2337/diabetes.52.5.1066
Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells: Roles of MAPKerk and MAPKp38
Diabetes May 2003, Vol.52, 1073-1080. doi:https://doi.org/10.2337/diabetes.52.5.1073
Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin
Coen H. Wiegman; Robert H.J. Bandsma; Margriet Ouwens; Fjodor H. van der Sluijs; Rick Havinga; Theo Boer; Dirk-Jan Reijngoud; Johannes A. Romijn; Folkert Kuipers
Diabetes May 2003, Vol.52, 1081-1089. doi:https://doi.org/10.2337/diabetes.52.5.1081
A Role for Suppressed Thermogenesis Favoring Catch-Up Fat in the Pathophysiology of Catch-Up Growth
Raffaella Crescenzo; Sonia Samec; Vladan Antic; Francoise Rohner-Jeanrenaud; Josiane Seydoux; Jean-Pierre Montani; Abdul G. Dulloo
Diabetes May 2003, Vol.52, 1090-1097. doi:https://doi.org/10.2337/diabetes.52.5.1090
Obesity Studies
Adipose Tissue Is a Major Source of Interleukin-1 Receptor Antagonist : Upregulation in Obesity and Inflammation
Cristiana E. Juge-Aubry; Emmanuel Somm; Vittorio Giusti; Agnès Pernin; Rachel Chicheportiche; Chantal Verdumo; Françoise Rohner-Jeanrenaud; Danielle Burger; Jean-Michel Dayer; Christoph A. Meier
Diabetes May 2003, Vol.52, 1104-1110. doi:https://doi.org/10.2337/diabetes.52.5.1104
Immunology and Transplantation
Adenovirus Early Region 3 Antiapoptotic 10.4K, 14.5K, and 14.7K Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice
Melissa A. Pierce; Harold D. Chapman; Cristina M. Post; Anton Svetlanov; Shimon Efrat; Marshall Horwitz; David V. Serreze
Diabetes May 2003, Vol.52, 1119-1127. doi:https://doi.org/10.2337/diabetes.52.5.1119
Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation
Diabetes May 2003, Vol.52, 1128-1136. doi:https://doi.org/10.2337/diabetes.52.5.1128
An Association of Autoantibody Status and Serum Cytokine Levels in Type 1 Diabetes
Diabetes May 2003, Vol.52, 1137-1142. doi:https://doi.org/10.2337/diabetes.52.5.1137
Islet Studies
A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line
Diabetes May 2003, Vol.52, 1147-1154. doi:https://doi.org/10.2337/diabetes.52.5.1147
Overexpression of PACAP in Transgenic Mouse Pancreatic β-Cells Enhances Insulin Secretion and Ameliorates Streptozotocin-induced Diabetes
Kyohei Yamamoto; Hitoshi Hashimoto; Shuhei Tomimoto; Norihito Shintani; Jun-ichi Miyazaki; Fumi Tashiro; Hiroyuki Aihara; Takao Nammo; Ming Li; Kazuya Yamagata; Jun-ichiro Miyagawa; Yuji Matsuzawa; Yuki Kawabata; Yuji Fukuyama; Kazumi Koga; Wakaba Mori; Kazuhiro Tanaka; Toshio Matsuda; Akemichi Baba
Diabetes May 2003, Vol.52, 1155-1162. doi:https://doi.org/10.2337/diabetes.52.5.1155
Analysis of Insulin-Producing Cells During In Vitro Differentiation From Feeder-Free Embryonic Stem Cells
Diabetes May 2003, Vol.52, 1163-1168. doi:https://doi.org/10.2337/diabetes.52.5.1163
Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated Apoptosis
Inik Chang; Sunshin Kim; Ja Young Kim; Namjoo Cho; Yun-Hee Kim; Hun Sik Kim; Moon-Kyu Lee; Kwang-Won Kim; Myung-Shik Lee
Diabetes May 2003, Vol.52, 1169-1175. doi:https://doi.org/10.2337/diabetes.52.5.1169
Intra-Islet Somatostatin Regulates Glucagon Release via Type 2 Somatostatin Receptors in Rats
Diabetes May 2003, Vol.52, 1176-1181. doi:https://doi.org/10.2337/diabetes.52.5.1176
Pathophysiology
Circulating Adiponectin Levels Are Reduced in Nonobese but Insulin-Resistant First-Degree Relatives of Type 2 Diabetic Patients
F. Pellmé; U. Smith; T. Funahashi; Y. Matsuzawa; H. Brekke; O. Wiklund; M.-R. Taskinen; P.-A. Jansson
Diabetes May 2003, Vol.52, 1182-1186. doi:https://doi.org/10.2337/diabetes.52.5.1182
Deleterious Effects of Acute Treatment With a Peroxisome Proliferator–Activated Receptor-γ Activator in Myocardial Ischemia and Reperfusion in Pigs
Ya Xu; Li Lu; Clifford Greyson; Jenny Lee; Michael Gen; Koichiro Kinugawa; Carlin S. Long; Gregory G. Schwartz
Diabetes May 2003, Vol.52, 1187-1194. doi:https://doi.org/10.2337/diabetes.52.5.1187
Sleep-Related Hypoglycemia-Associated Autonomic Failure in Type 1 Diabetes: Reduced Awakening From Sleep During Hypoglycemia
Diabetes May 2003, Vol.52, 1195-1203. doi:https://doi.org/10.2337/diabetes.52.5.1195
Complications
A Low-Iron-Available, Polyphenol-Enriched, Carbohydrate-Restricted Diet to Slow Progression of Diabetic Nephropathy
Diabetes May 2003, Vol.52, 1204-1209. doi:https://doi.org/10.2337/diabetes.52.5.1204
Plasma Prekallikrein: A Risk Marker for Hypertension and Nephropathy in Type 1 Diabetes
Ayad A. Jaffa; Ramon Durazo-Arvizu; Deyi Zheng; Daniel T. Lackland; Sujata Srikanth; W. Timothy Garvey; Alvin H. Schmaier; the DCCT/EDIC Study Group
Diabetes May 2003, Vol.52, 1215-1221. doi:https://doi.org/10.2337/diabetes.52.5.1215
Maternal Diabetes In Vivo and High Glucose In Vitro Diminish GAPDH Activity in Rat Embryos
Diabetes May 2003, Vol.52, 1222-1228. doi:https://doi.org/10.2337/diabetes.52.5.1222
Increased Expression of Ornithine Decarboxylase in Distal Tubules of Early Diabetic Rat Kidneys: Are Polyamines Paracrine Hypertrophic Factors?
Aihua Deng; Karen A. Munger; Jose M. Valdivielso; Joseph Satriano; Mark Lortie; Roland C. Blantz; Scott C. Thomson
Diabetes May 2003, Vol.52, 1235-1239. doi:https://doi.org/10.2337/diabetes.52.5.1235
A Novel Role for CD36 in VLDL-Enhanced Platelet Activation
Diabetes May 2003, Vol.52, 1248-1255. doi:https://doi.org/10.2337/diabetes.52.5.1248
High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells
Diabetes May 2003, Vol.52, 1256-1264. doi:https://doi.org/10.2337/diabetes.52.5.1256
Genetics
Endothelial Nitric Oxide Synthase Polymorphisms Are Associated With Type 2 Diabetes and the Insulin Resistance Syndrome
Lucilla D. Monti; Cristina Barlassina; Lorena Citterio; Elena Galluccio; Carlo Berzuini; Emanuela Setola; Gianpietro Valsecchi; Pietro Lucotti; Guido Pozza; Luisa Bernardinelli; Giorgio Casari; PierMarco Piatti
Diabetes May 2003, Vol.52, 1270-1275. doi:https://doi.org/10.2337/diabetes.52.5.1270
Brief Genetics Reports
Genetic Variation in the Small Heterodimer Partner Gene and Young-Onset Type 2 Diabetes, Obesity, and Birth Weight in U.K. Subjects
Simon M.S. Mitchell; Michael N. Weedon; Katharine R. Owen; Beverley Shields; Beverley Wilkins-Wall; Mark Walker; Mark I. McCarthy; Timothy M. Frayling; Andrew T. Hattersley
Diabetes May 2003, Vol.52, 1276-1279. doi:https://doi.org/10.2337/diabetes.52.5.1276
A Common Polymorphism in the Promoter of UCP2 Contributes to the Variation in Insulin Secretion in Glucose-Tolerant Subjects
Giorgio Sesti; Marina Cardellini; Maria Adelaide Marini; Simona Frontoni; Monica D’Adamo; Silvia Del Guerra; Davide Lauro; Pierluigi De Nicolais; Paolo Sbraccia; Stefano Del Prato; Sergio Gambardella; Massimo Federici; Piero Marchetti; Renato Lauro
Diabetes May 2003, Vol.52, 1280-1283. doi:https://doi.org/10.2337/diabetes.52.5.1280
Linkage for BMI at 3q27 Region Confirmed in an African-American Population
Diabetes May 2003, Vol.52, 1284-1287. doi:https://doi.org/10.2337/diabetes.52.5.1284
Contribution of Variants in the Small Heterodimer Partner Gene to Birthweight, Adiposity, and Insulin Levels: Mutational Analysis and Association Studies in Multiple Populations
Chiao-Chien Connie Hung; I. Sadaf Farooqi; Ken Ong; Jian’an Luan; Julia M. Keogh; Marcus Pembrey; Giles S.H. Yeo; David Dunger; Nicholas J. Wareham; Stephen O’ Rahilly
Diabetes May 2003, Vol.52, 1288-1291. doi:https://doi.org/10.2337/diabetes.52.5.1288
Genetic Variation in the Human Winged Helix/Forkhead Transcription Factor Gene FOXC2 in Pima Indians
Diabetes May 2003, Vol.52, 1292-1295. doi:https://doi.org/10.2337/diabetes.52.5.1292
Association of Polymorphisms in GPR10, the Gene Encoding the Prolactin-Releasing Peptide Receptor With Blood Pressure, but not Obesity, in a U.K. Caucasian Population
Sumit Bhattacharyya; Jian’an Luan; Benjamin Challis; Catherine Schmitz; Paul Clarkson; Paul W. Franks; Rita Middelberg; Julia Keogh; I. Sadaf Farooqi; Carl Montague; John Brennand; Nicholas J. Wareham; Stephen O’Rahilly
Diabetes May 2003, Vol.52, 1296-1299. doi:https://doi.org/10.2337/diabetes.52.5.1296
Association and Haplotype Analysis of the Insulin-Degrading Enzyme (IDE) Gene, a Strong Positional and Biological Candidate for Type 2 Diabetes Susceptibility
Christopher J. Groves; Steven Wiltshire; Damian Smedley; Katherine R. Owen; Timothy M. Frayling; Mark Walker; Graham A. Hitman; Jonathan C. Levy; Stephen O’Rahilly; Stephan Menzel; Andrew T. Hattersley; Mark I. McCarthy
Diabetes May 2003, Vol.52, 1300-1305. doi:https://doi.org/10.2337/diabetes.52.5.1300
