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Issues
1 July 2003
ISSN 0012-1797
EISSN 1939-327X
Rapid Publication
Magnetic Resonance-Defined Periportal Steatosis Following Intraportal Islet Transplantation: A Functional Footprint of Islet Graft Survival?
James F. Markmann; Mark Rosen; Evan S. Siegelman; Michael C. Soulen; Shaoping Deng; Clyde F. Barker; Ali Naji
Diabetes July 2003, Vol.52, 1591-1594. doi:https://doi.org/10.2337/diabetes.52.7.1591
Perspectives in Diabetes
Lilly Lecture 2002: Islet Transplantation: A Brave New World
Diabetes July 2003, Vol.52, 1595-1603. doi:https://doi.org/10.2337/diabetes.52.7.1595
New Methodologies and Databases
Transcriptional Program of the Endocrine Pancreas in Mice and Humans
Klaus H. Kaestner; Catherine S. Lee; L. Marie Scearce; John E. Brestelli; Athanasios Arsenlis; Phillip Phuc Le; Kristen A. Lantz; Jonathan Crabtree; Angel Pizarro; Joan Mazzarelli; Deborah Pinney; Steve Fischer; Elisabetta Manduchi; Christian J. Stoeckert, Jr.; Gerard Gradwohl; Sandra W. Clifton; Juliana R. Brown; Hiroshi Inoue; Corentin Cras-Méneur; M. Alan Permutt
Diabetes July 2003, Vol.52, 1604-1610. doi:https://doi.org/10.2337/diabetes.52.7.1604
Metabolism
A Promoter Genotype and Oxidative Stress Potentially Link Resistin to Human Insulin Resistance
Diabetes July 2003, Vol.52, 1611-1618. doi:https://doi.org/10.2337/diabetes.52.7.1611
Weight Loss-Induced Plasticity of Glucose Transport and Phosphorylation in the Insulin Resistance of Obesity and Type 2 Diabetes
Diabetes July 2003, Vol.52, 1619-1626. doi:https://doi.org/10.2337/diabetes.52.7.1619
Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling
Joost J.F.P. Luiken; Susan L.M. Coort; Jodil Willems; Will A. Coumans; Arend Bonen; Ger J. van der Vusse; Jan F.C. Glatz
Diabetes July 2003, Vol.52, 1627-1634. doi:https://doi.org/10.2337/diabetes.52.7.1627
What Does the Measurement of Whole-Body Fatty Acid Rate of Appearance in Plasma by Using a Fatty Acid Tracer Really Mean?
Diabetes July 2003, Vol.52, 1641-1648. doi:https://doi.org/10.2337/diabetes.52.7.1641
Mechanisms by Which Liver-Specific PEPCK Knockout Mice Preserve Euglycemia During Starvation
Pengxiang She; Shawn C. Burgess; Masakazu Shiota; Paul Flakoll; E. Patrick Donahue; Craig R. Malloy; A. Dean Sherry; Mark A. Magnuson
Diabetes July 2003, Vol.52, 1649-1654. doi:https://doi.org/10.2337/diabetes.52.7.1649
Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors
Masanori Iwaki; Morihiro Matsuda; Norikazu Maeda; Tohru Funahashi; Yuji Matsuzawa; Makoto Makishima; Iichiro Shimomura
Diabetes July 2003, Vol.52, 1655-1663. doi:https://doi.org/10.2337/diabetes.52.7.1655
Signal Transduction
Duodenal Leptin Stimulates Cholecystokinin Secretion: Evidence of a Positive Leptin-Cholecystokinin Feedback Loop
Diabetes July 2003, Vol.52, 1664-1672. doi:https://doi.org/10.2337/diabetes.52.7.1664
Obesity Studies
Expression of Peroxisome Proliferator-Activated Receptor-γ1 and Peroxisome Proliferator-Activated Receptor-γ2 in Visceral and Subcutaneous Adipose Tissue of Obese Women
Vittorio Giusti; Chantal Verdumo; Michel Suter; Rolf Christian Gaillard; Peter Burckhardt; Francois Pralong
Diabetes July 2003, Vol.52, 1673-1676. doi:https://doi.org/10.2337/diabetes.52.7.1673
Immunology and Transplantation
Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains
Marie-Louise Bergman; Nadia Duarte; Susana Campino; Marie Lundholm; Vinicius Motta; Kristina Lejon; Carlos Penha-Gonçalves; Dan Holmberg
Diabetes July 2003, Vol.52, 1677-1682. doi:https://doi.org/10.2337/diabetes.52.7.1677
Glucagon, Catecholamine, and Symptom Responses to Hypoglycemia in Living Donors of Pancreas Segments
Diabetes July 2003, Vol.52, 1689-1694. doi:https://doi.org/10.2337/diabetes.52.7.1689
Islet Studies
HIV Protease Inhibitors Acutely Impair Glucose-Stimulated Insulin Release
Diabetes July 2003, Vol.52, 1695-1700. doi:https://doi.org/10.2337/diabetes.52.7.1695
Replication Increases β-Cell Vulnerability to Human Islet Amyloid Polypeptide-Induced Apoptosis
Diabetes July 2003, Vol.52, 1701-1708. doi:https://doi.org/10.2337/diabetes.52.7.1701
The Daily Rhythm in Plasma Glucagon Concentrations in the Rat Is Modulated by the Biological Clock and by Feeding Behavior
Marieke Ruiter; Susanne E. La Fleur; Caroline van Heijningen; Jan van der Vliet; Andries Kalsbeek; Ruud M. Buijs
Diabetes July 2003, Vol.52, 1709-1715. doi:https://doi.org/10.2337/diabetes.52.7.1709
Increased Islet Volume but Unchanged Islet Number in ob/ob Mice
Diabetes July 2003, Vol.52, 1716-1722. doi:https://doi.org/10.2337/diabetes.52.7.1716
Dynamics of Calcium Clearance in Mouse Pancreatic β-Cells
Diabetes July 2003, Vol.52, 1723-1731. doi:https://doi.org/10.2337/diabetes.52.7.1723
PDX-1 Protein Containing Its Own Antennapedia-Like Protein Transduction Domain Can Transduce Pancreatic Duct and Islet Cells
Diabetes July 2003, Vol.52, 1732-1737. doi:https://doi.org/10.2337/diabetes.52.7.1732
Pathophysiology
Mechanisms of the Age-Associated Deterioration in Glucose Tolerance: Contribution of Alterations in Insulin Secretion, Action, and Clearance
Rita Basu; Elena Breda; Ann L. Oberg; Claudia C. Powell; Chiara Dalla Man; Ananda Basu; Janet L. Vittone; George G. Klee; Puneet Arora; Michael D. Jensen; Gianna Toffolo; Claudio Cobelli; Robert A. Rizza
Diabetes July 2003, Vol.52, 1738-1748. doi:https://doi.org/10.2337/diabetes.52.7.1738
Estrogen Blunts Neuroendocrine and Metabolic Responses to Hypoglycemia
Diabetes July 2003, Vol.52, 1749-1755. doi:https://doi.org/10.2337/diabetes.52.7.1749
β-Cell Capacity and Insulin Sensitivity in Prepubertal Children Born Small for Gestational Age: Influence of Body Size During Childhood
Margreet A. Veening; Mirjam M. van Weissenbruch; Robert J. Heine; Henriette A. Delemarre-van de Waal
Diabetes July 2003, Vol.52, 1756-1760. doi:https://doi.org/10.2337/diabetes.52.7.1756
Effect of Antecedent Hypoglycemia on Counterregulatory Responses to Subsequent Euglycemic Exercise in Type 1 Diabetes
Diabetes July 2003, Vol.52, 1761-1769. doi:https://doi.org/10.2337/diabetes.52.7.1761
Peroxisome Proliferator–Activated Receptor-α Agonist Treatment in a Transgenic Model of Type 2 Diabetes Reverses the Lipotoxic State and Improves Glucose Homeostasis
Hyunsook Kim; Martin Haluzik; Zeenat Asghar; Daphne Yau; Jamie W. Joseph; Ana M. Fernandez; Marc L. Reitman; Shoshana Yakar; Bethel Stannard; Lisa Heron-Milhavet; Michael B. Wheeler; Derek LeRoith
Diabetes July 2003, Vol.52, 1770-1778. doi:https://doi.org/10.2337/diabetes.52.7.1770
Adiponectin Expression From Human Adipose Tissue: Relation to Obesity, Insulin Resistance, and Tumor Necrosis Factor-α Expression
Diabetes July 2003, Vol.52, 1779-1785. doi:https://doi.org/10.2337/diabetes.52.7.1779
The GLP-1 Derivative NN2211 Restores β-Cell Sensitivity to Glucose in Type 2 Diabetic Patients After a Single Dose
Annette M. Chang; Grethe Jakobsen; Jeppe Sturis; Marla J. Smith; Cathie J. Bloem; Bob An; Andrzej Galecki; Jeffrey B. Halter
Diabetes July 2003, Vol.52, 1786-1791. doi:https://doi.org/10.2337/diabetes.52.7.1786
Insulin-Dependent Modulation of Plasma Ghrelin and Leptin Concentrations Is Less Pronounced in Type 2 Diabetic Patients
Christian Anderwald; Georg Brabant; Elisabeth Bernroider; Rüdiger Horn; Attila Brehm; Werner Waldhäusl; Michael Roden
Diabetes July 2003, Vol.52, 1792-1798. doi:https://doi.org/10.2337/diabetes.52.7.1792
Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study
Bruce B. Duncan; Maria Inês Schmidt; James S. Pankow; Christie M. Ballantyne; David Couper; Alvaro Vigo; Ron Hoogeveen; Aaron R. Folsom; Gerardo Heiss
Diabetes July 2003, Vol.52, 1799-1805. doi:https://doi.org/10.2337/diabetes.52.7.1799
Complications
Relationship Between Diurnal Blood Pressure, Renal Hemodynamic Function, and the Renin-Angiotensin System in Type 1 Diabetes
Diabetes July 2003, Vol.52, 1806-1811. doi:https://doi.org/10.2337/diabetes.52.7.1806
Effects of Duration and Age at Onset of Type 1 Diabetes on Preclinical Manifestations of Nephropathy
Keith N. Drummond; Michael S. Kramer; Samy Suissa; Claire Lévy-Marchal; Sophie Dell’Aniello; Alan Sinaiko; Michael Mauer; for the *International Diabetic Nephropathy Study Group
Diabetes July 2003, Vol.52, 1818-1824. doi:https://doi.org/10.2337/diabetes.52.7.1818
Chronic Diabetes Increases Advanced Glycation End Products on Cardiac Ryanodine Receptors/Calcium-Release Channels
Keshore R. Bidasee; Karuna Nallani; Yongqi Yu; Ross R. Cocklin; Yinong Zhang; Mu Wang; Ü. Deniz Dincer; Henry R. Besch, Jr.
Diabetes July 2003, Vol.52, 1825-1836. doi:https://doi.org/10.2337/diabetes.52.7.1825
Exercise Training Improves Baroreflex Sensitivity in Type 2 Diabetes
Diabetes July 2003, Vol.52, 1837-1842. doi:https://doi.org/10.2337/diabetes.52.7.1837
Glucose Enhances Endothelial LOX-1 Expression: Role for LOX-1 in Glucose-Induced Human Monocyte Adhesion to Endothelium
Diabetes July 2003, Vol.52, 1843-1850. doi:https://doi.org/10.2337/diabetes.52.7.1843
Insulin Acutely Increases Fibrinogen Production in Individuals With Type 2 Diabetes but Not in Individuals Without Diabetes
Diabetes July 2003, Vol.52, 1851-1856. doi:https://doi.org/10.2337/diabetes.52.7.1851
Genetics
Young-Onset Type 2 Diabetes Families Are the Major Contributors to Genetic Loci in the Diabetes UK Warren 2 Genome Scan and Identify Putative Novel Loci on Chromosomes 8q21, 21q22, and 22q11
Timothy M. Frayling; Steven Wiltshire; Graham A. Hitman; Mark Walker; Jonathan C. Levy; Mike Sampson; Christopher J. Groves; Stephan Menzel; Mark I. McCarthy; Andrew T. Hattersley
Diabetes July 2003, Vol.52, 1857-1863. doi:https://doi.org/10.2337/diabetes.52.7.1857
Brief Genetics Report
Promoter Polymorphisms of the TNF-α (G-308A) and IL-6 (C-174G) Genes Predict the Conversion From Impaired Glucose Tolerance to Type 2 Diabetes: The Finnish Diabetes Prevention Study
Agata Kubaszek; Jussi Pihlajamäki; Vladislav Komarovski; Virpi Lindi; Jaana Lindström; Johan Eriksson; Timo T. Valle; Helena Hämäläinen; Pirjo Ilanne-Parikka; Sirkka Keinänen-Kiukaanniemi; Jaakko Tuomilehto; Matti Uusitupa; Markku Laakso
Diabetes July 2003, Vol.52, 1872-1876. doi:https://doi.org/10.2337/diabetes.52.7.1872
