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Metabolism

Effect of Training on Muscle Triacylglycerol and Structural Lipids: A Relation to Insulin Sensitivity?

Jørn W. Helge; Flemming Dela

Abstract

View articletitled, Effect of Training on Muscle Triacylglycerol and Structural Lipids: A Relation to Insulin Sensitivity?

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Topics: fatty acids , glucose , insulin sensitivity , leg , lipids

Diabetes August 2003, Vol.52, 1881-1887. doi:https://doi.org/10.2337/diabetes.52.8.1881

Impact of Aerobic Exercise Training on Age-Related Changes in Insulin Sensitivity and Muscle Oxidative Capacity

Kevin R. Short; Janet L. Vittone; Maureen L. Bigelow; David N. Proctor; Robert A. Rizza; Jill M. Coenen-Schimke; K. Sreekumaran Nair

Abstract

View articletitled, Impact of Aerobic Exercise Training on Age-Related Changes in Insulin Sensitivity and Muscle Oxidative Capacity

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Topics: abdomen , enzymes , glucose , insulin , insulin sensitivity

Diabetes August 2003, Vol.52, 1888-1896. doi:https://doi.org/10.2337/diabetes.52.8.1888

Interaction of Insulin and Prior Exercise in Control of Hepatic Metabolism of a Glucose Load

R. Richard Pencek; Freyja James; D. Brooks Lacy; Kareem Jabbour; Phillip E. Williams; Patrick T. Fueger; David H. Wasserman

Abstract

View articletitled, Interaction of Insulin and Prior Exercise in Control of Hepatic Metabolism of a Glucose Load

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Topics: basal insulin , glucose , insulin , dog, domestic , lack of exercise

Diabetes August 2003, Vol.52, 1897-1903. doi:https://doi.org/10.2337/diabetes.52.8.1897

Signal Transduction

Chronic Endothelin-1 Treatment Leads to Insulin Resistance In Vivo

Jason J. Wilkes; Andrea Hevener; Jerrold Olefsky

Abstract

View articletitled, Chronic Endothelin-1 Treatment Leads to Insulin Resistance In Vivo

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Topics: endothelin-1 , insulin , insulin resistance , irs1 protein, human , glucose

Diabetes August 2003, Vol.52, 1904-1909. doi:https://doi.org/10.2337/diabetes.52.8.1904

Insulin Resistance in Tetracycline-Repressible Munc18c Transgenic Mice

Beth A. Spurlin; Rhonda M. Thomas; Angela K. Nevins; Hyo-Jeong Kim; Yoon-Jung Kim; Hye-Lim Noh; Gerald I. Shulman; Jason K. Kim; Debbie C. Thurmond

Abstract

View articletitled, Insulin Resistance in Tetracycline-Repressible Munc18c Transgenic Mice

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Topics: insulin , insulin resistance , mice , mice, transgenic , tetracycline

Diabetes August 2003, Vol.52, 1910-1917. doi:https://doi.org/10.2337/diabetes.52.8.1910

A Peroxovanadium Compound Stimulates Muscle Glucose Transport as Powerfully as Insulin and Contractions Combined

Lorraine A. Nolte; Dong-Ho Han; Polly A. Hansen; Kathleen A. Hucker; John O. Holloszy

Abstract

View articletitled, A Peroxovanadium Compound Stimulates Muscle Glucose Transport as Powerfully as Insulin and Contractions Combined

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Topics: bovine papillomavirus , glucose transport , insulin

Diabetes August 2003, Vol.52, 1918-1925. doi:https://doi.org/10.2337/diabetes.52.8.1918

Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO₄)₃ Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise

Mary Beeson; Mini P. Sajan; Michelle Dizon; Dmitry Grebenev; Joaquin Gomez-Daspet; Atsushi Miura; Yoshinori Kanoh; Jennifer Powe; Gautam Bandyopadhyay; Mary L. Standaert; Robert V. Farese

Abstract

View articletitled, Activation of Protein Kinase C-ζ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 Is Defective in Muscle in Type 2 Diabetes and Impaired Glucose Tolerance: Amelioration by Rosiglitazone and Exercise

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Topics: 1-phosphatidylinositol 3-kinase , insulin , rosiglitazone , skeletal muscles , glucose

Diabetes August 2003, Vol.52, 1926-1934. doi:https://doi.org/10.2337/diabetes.52.8.1926

Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction

Young-Bum Kim; Ko Kotani; Theodore P. Ciaraldi; Robert R. Henry; Barbara B. Kahn

Abstract

View articletitled, Insulin-Stimulated Protein Kinase C λ/ζ Activity Is Reduced in Skeletal Muscle of Humans With Obesity and Type 2 Diabetes: Reversal With Weight Reduction

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Topics: 1-phosphatidylinositol 3-kinase , insulin , obesity , weight reduction , irs1 protein, human

Diabetes August 2003, Vol.52, 1935-1942. doi:https://doi.org/10.2337/diabetes.52.8.1935

Rosiglitazone Improves Downstream Insulin Receptor Signaling in Type 2 Diabetic Patients

Yoshinori Miyazaki; Helen He; Lawrence J. Mandarino; Ralph A. DeFronzo

Abstract

View articletitled, Rosiglitazone Improves Downstream Insulin Receptor Signaling in Type 2 Diabetic Patients

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Topics: insulin , insulin receptor , rosiglitazone , plasma glucose , glucose

Diabetes August 2003, Vol.52, 1943-1950. doi:https://doi.org/10.2337/diabetes.52.8.1943

Obesity

Central Pro-opiomelanocortin Gene Delivery Results in Hypophagia, Reduced Visceral Adiposity, and Improved Insulin Sensitivity in Genetically Obese Zucker Rats

Gang Li; Charles V. Mobbs; Philip J. Scarpace

Abstract

View articletitled, Central Pro-opiomelanocortin Gene Delivery Results in Hypophagia, Reduced Visceral Adiposity, and Improved Insulin Sensitivity in Genetically Obese Zucker Rats

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Topics: obesity , pro-opiomelanocortin , rats, zucker , spatial vectors , hypothalamus

Diabetes August 2003, Vol.52, 1951-1957. doi:https://doi.org/10.2337/diabetes.52.8.1951

Variation in Type 2 Diabetes-Related Traits in Mouse Strains Susceptible to Diet-Induced Obesity

Martin Rossmeisl; Jong S. Rim; Robert A. Koza; Leslie P. Kozak

Abstracts

View articletitled, Variation in Type 2 Diabetes-Related Traits in Mouse Strains Susceptible to Diet-Induced Obesity

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Topics: diet , diet, high-fat , insulin , mice , obesity

Diabetes August 2003, Vol.52, 1958-1966. doi:https://doi.org/10.2337/diabetes.52.8.1958

Immunology

Blockade of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Exacerbates Type 1 Diabetes in NOD Mice

Qing-Sheng Mi; Dalam Ly; S.-E. Lamhamedi-Cherradi; Konstantin V. Salojin; Li Zhou; Marsha Grattan; Craig Meagher; Peter Zucker; Youhai H. Chen; James Nagle; Dennis Taub; Terry L. Delovitch

Abstract

View articletitled, Blockade of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Exacerbates Type 1 Diabetes in NOD Mice

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Topics: apoptosis , diabetes mellitus, type 1 , endocrine pancreas , mice , mice, inbred nod

Diabetes August 2003, Vol.52, 1967-1975. doi:https://doi.org/10.2337/diabetes.52.8.1967

Prevention of Diabetes in NOD Mice by Administration of Dendritic Cells Deficient in Nuclear Transcription Factor-κB Activity

Linlin Ma; Shiguang Qian; Xiaoyan Liang; Lianfu Wang; Jennifer E. Woodward; Nick Giannoukakis; Paul D. Robbins; Suzanne Bertera; Massimo Trucco; John J. Fung; Lina Lu

Abstract

View articletitled, Prevention of Diabetes in NOD Mice by Administration of Dendritic Cells Deficient in Nuclear Transcription Factor-κB Activity

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Topics: mice, inbred nod , oligodeoxyribonucleotides , t-lymphocytes , antigens

Diabetes August 2003, Vol.52, 1976-1985. doi:https://doi.org/10.2337/diabetes.52.8.1976

Islet

Endothelial Differentiation Gene Receptors in Pancreatic Islets and INS-1 Cells

Suzanne G. Laychock; Yingrao Tian; Shawn M. Sessanna

Abstract

View articletitled, Endothelial Differentiation Gene Receptors in Pancreatic Islets and INS-1 Cells

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Topics: cyclic amp , glucose , rna, messenger , sphingosine-1-phosphate receptors , insulin

Diabetes August 2003, Vol.52, 1986-1993. doi:https://doi.org/10.2337/diabetes.52.8.1986

Free Radicals and the Pathogenesis of Type 1 Diabetes: β-Cell Cytokine-Mediated Free Radical Generation Via Cyclooxygenase-2

Tahereh Tabatabaie; Angelica Vasquez-Weldon; Danny R. Moore; Yashige Kotake

Abstract

View articletitled, Free Radicals and the Pathogenesis of Type 1 Diabetes: β-Cell Cytokine-Mediated Free Radical Generation Via Cyclooxygenase-2

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Topics: cytokine , free radicals , pancreas , cyclooxygenase-2

Diabetes August 2003, Vol.52, 1994-1999. doi:https://doi.org/10.2337/diabetes.52.8.1994

Small-Conductance Calcium-Activated K⁺ Channels Are Expressed in Pancreatic Islets and Regulate Glucose Responses

Natalia A. Tamarina; Yong Wang; Loris Mariotto; Andrey Kuznetsov; Chris Bond; John Adelman; Louis H. Philipson

Abstract

View articletitled, Small-Conductance Calcium-Activated K+ Channels Are Expressed in Pancreatic Islets and Regulate Glucose Responses

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Topics: apamin , endocrine pancreas , glucose , mice , tea

Diabetes August 2003, Vol.52, 2000-2006. doi:https://doi.org/10.2337/diabetes.52.8.2000

Characterization of Endocrine Progenitor Cells and Critical Factors for Their Differentiation in Human Adult Pancreatic Cell Culture

Ru Gao; Jarkko Ustinov; Mari-Anne Pulkkinen; Karolina Lundin; Olle Korsgren; Timo Otonkoski

Abstract

View articletitled, Characterization of Endocrine Progenitor Cells and Critical Factors for Their Differentiation in Human Adult Pancreatic Cell Culture

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Topics: bromodeoxyuridine , insulin , pancreas , transplantation , stem cells

Diabetes August 2003, Vol.52, 2007-2015. doi:https://doi.org/10.2337/diabetes.52.8.2007

Pancreatic Precursors and Differentiated Islet Cell Types From Murine Embryonic Stem Cells: An In Vitro Model to Study Islet Differentiation

Brenda W. Kahan; Lynn M. Jacobson; Debra A. Hullett; Jaime M. Ochoada; Terry D. Oberley; Katharine M. Lang; Jon S. Odorico

Abstract

View articletitled, Pancreatic Precursors and Differentiated Islet Cell Types From Murine Embryonic Stem Cells: An In Vitro Model to Study Islet Differentiation

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Topics: embryonic stem cells , hormones , mice , pancreas , endocrine pancreas

Diabetes August 2003, Vol.52, 2016-2024. doi:https://doi.org/10.2337/diabetes.52.8.2016

Diabetogenic Potential of Human Pathogens Uncovered in Experimentally Permissive β-Cells

Malin Flodström; Devin Tsai; Cody Fine; Amy Maday; Nora Sarvetnick

Abstracts

View articletitled, Diabetogenic Potential of Human Pathogens Uncovered in Experimentally Permissive β-Cells

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Topics: coxsackievirus b3 , infections , mice , lymphocytic choriomeningitis virus , pancreas

Diabetes August 2003, Vol.52, 2025-2034. doi:https://doi.org/10.2337/diabetes.52.8.2025

Label-Retaining Cells in the Rat Pancreas: Location and Differentiation Potential in Vitro

Bertrand Duvillié; Myriam Attali; Virginie Aiello; Eric Quemeneur; Raphael Scharfmann

Abstract

View articletitled, Label-Retaining Cells in the Rat Pancreas: Location and Differentiation Potential in Vitro

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Topics: bromodeoxyuridine , pancreas , insulin

Diabetes August 2003, Vol.52, 2035-2042. doi:https://doi.org/10.2337/diabetes.52.8.2035

K_ATP Channels and Pancreatic Islet Blood Flow in Anesthetized Rats: Increased Blood Flow Induced by Potassium Channel Openers

Leif Jansson; Mikael Kullin; F. Anders Karlsson; Birgitta Bodin; John Bondo Hansen; Stellan Sandler

Abstract

View articletitled, KATP Channels and Pancreatic Islet Blood Flow in Anesthetized Rats: Increased Blood Flow Induced by Potassium Channel Openers

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Topics: diazoxide , glipizide , vascular flow , insulin , pancreas

Diabetes August 2003, Vol.52, 2043-2048. doi:https://doi.org/10.2337/diabetes.52.8.2043

Insulin Constitutively Secreted by β-Cells Is Necessary for Glucose-Stimulated Insulin Secretion

Siddhartha Srivastava; H. Joseph Goren

Abstract

View articletitled, Insulin Constitutively Secreted by β-Cells Is Necessary for Glucose-Stimulated Insulin Secretion

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Topics: glucose , insulin , insulin secretion

Diabetes August 2003, Vol.52, 2049-2056. doi:https://doi.org/10.2337/diabetes.52.8.2049

Pancreatic β-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase

Maria Sörhede Winzell; Håkan Svensson; Sven Enerbäck; Kim Ravnskjaer; Susanne Mandrup; Victoria Esser; Peter Arner; Marie-Clotilde Alves-Guerra; Bruno Miroux; Frank Sundler; Bo Ahrén; Cecilia Holm

Abstract

View articletitled, Pancreatic β-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase

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Topics: animals, transgenic , diet, high-fat , glucose , insulin , insulin secretion

Diabetes August 2003, Vol.52, 2057-2065. doi:https://doi.org/10.2337/diabetes.52.8.2057

Vesicular Inhibitory Amino Acid Transporter Is Present in Glucagon-Containing Secretory Granules in αTC6 Cells, Mouse Clonal α-Cells, and α-Cells of Islets of Langerhans

Mitsuko Hayashi; Masato Otsuka; Riyo Morimoto; Akiko Muroyama; Shunsuke Uehara; Akitsugu Yamamoto; Yoshinori Moriyama

Abstract

View articletitled, Vesicular Inhibitory Amino Acid Transporter Is Present in Glucagon-Containing Secretory Granules in αTC6 Cells, Mouse Clonal α-Cells, and α-Cells of Islets of Langerhans

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Topics: amino acid transporter , antibodies , endocrine pancreas , gamma-aminobutyric acid , glucagon

Diabetes August 2003, Vol.52, 2066-2074. doi:https://doi.org/10.2337/diabetes.52.8.2066

Pathophysiology

Vascular Endothelial Function and Blood Pressure Homeostasis in Mice Overexpressing IGF Binding Protein-1

Stephen B. Wheatcroft; Mark T. Kearney; Ajay M. Shah; David J. Grieve; Ian L. Williams; John P. Miell; Paul A. Crossey

Abstract

View articletitled, Vascular Endothelial Function and Blood Pressure Homeostasis in Mice Overexpressing IGF Binding Protein-1

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Topics: endothelium , insulin , insulin-like growth factor i , insulin-like growth-factor binding protein 1 , insulin-like growth-factor-binding proteins

Diabetes August 2003, Vol.52, 2075-2082. doi:https://doi.org/10.2337/diabetes.52.8.2075

Cortisol Elevations Comparable to Those That Occur During Hypoglycemia Do Not Cause Hypoglycemia-Associated Autonomic Failure

Bharathi Raju; Veronica P. McGregor; Philip E. Cryer

Abstracts

View articletitled, Cortisol Elevations Comparable to Those That Occur During Hypoglycemia Do Not Cause Hypoglycemia-Associated Autonomic Failure

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Topics: hydrocortisone , hypoglycemia , hypoglycemic agents , saline solutions , pure autonomic failure

Diabetes August 2003, Vol.52, 2083-2089. doi:https://doi.org/10.2337/diabetes.52.8.2083

Higher Offspring Birth Weight Predicts the Metabolic Syndrome in Mothers but Not Fathers 8 Years After Delivery: The Pune Children’s Study

Chittaranjan S. Yajnik; Charu V. Joglekar; Anand N. Pandit; Ashish R. Bavdekar; Swati A. Bapat; Sheila A. Bhave; Samantha D. Leary; Caroline H.D. Fall

Abstract

View articletitled, Higher Offspring Birth Weight Predicts the Metabolic Syndrome in Mothers but Not Fathers 8 Years After Delivery: The Pune Children’s Study

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Topics: birth weight , metabolic syndrome x , child , obesity , insulin

Diabetes August 2003, Vol.52, 2090-2096. doi:https://doi.org/10.2337/diabetes.52.8.2090

Inflammation-Sensitive Plasma Proteins Are Associated With Future Weight Gain

Gunnar Engström; Bo Hedblad; Lars Stavenow; Peter Lind; Lars Janzon; Folke Lindgärde

Abstract

View articletitled, Inflammation-Sensitive Plasma Proteins Are Associated With Future Weight Gain

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Topics: inflammation , weight gain , plasma proteins , follow-up

Diabetes August 2003, Vol.52, 2097-2101. doi:https://doi.org/10.2337/diabetes.52.8.2097

Complications

Protein Kinase Cβ Selective Inhibitor LY333531 Attenuates Diabetic Hyperalgesia Through Ameliorating cGMP Level of Dorsal Root Ganglion Neurons

Hyoh Kim; Teiji Sasaki; Kengo Maeda; Daisuke Koya; Atsunori Kashiwagi; Hitoshi Yasuda

Abstract

View articletitled, Protein Kinase Cβ Selective Inhibitor LY333531 Attenuates Diabetic Hyperalgesia Through Ameliorating cGMP Level of Dorsal Root Ganglion Neurons

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Topics: cyclic gmp , ganglia, spinal , hyperalgesia , neurons , rats

Diabetes August 2003, Vol.52, 2102-2109. doi:https://doi.org/10.2337/diabetes.52.8.2102

Prevention of Incipient Diabetic Nephropathy by High-Dose Thiamine and Benfotiamine

Roya Babaei-Jadidi; Nikolaos Karachalias; Naila Ahmed; Sinan Battah; Paul J. Thornalley

Abstract

View articletitled, Prevention of Incipient Diabetic Nephropathy by High-Dose Thiamine and Benfotiamine

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Topics: streptozocin , thiamine , rats

Diabetes August 2003, Vol.52, 2110-2120. doi:https://doi.org/10.2337/diabetes.52.8.2110

Leptin Increases Lipoprotein Lipase Secretion by Macrophages: Involvement of Oxidative Stress and Protein Kinase C

Fritz Maingrette; Geneviève Renier

Abstract

View articletitled, Leptin Increases Lipoprotein Lipase Secretion by Macrophages: Involvement of Oxidative Stress and Protein Kinase C

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Topics: leptin , macrophages , bodily secretions

Diabetes August 2003, Vol.52, 2121-2128. doi:https://doi.org/10.2337/diabetes.52.8.2121

Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia

Tze-Jen Huang; Sally A. Price; Lucy Chilton; Nigel A. Calcutt; David R. Tomlinson; Alex Verkhratsky; Paul Fernyhough

Abstract

View articletitled, Insulin Prevents Depolarization of the Mitochondrial Inner Membrane in Sensory Neurons of Type 1 Diabetic Rats in the Presence of Sustained Hyperglycemia

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Topics: insulin , mitochondria , neurons, afferent , rats , streptozocin

Diabetes August 2003, Vol.52, 2129-2136. doi:https://doi.org/10.2337/diabetes.52.8.2129

Production of N^ε-(Carboxymethyl)Lysine Is Impaired in Mice Deficient in NADPH Oxidase: A Role for Phagocyte-Derived Oxidants in the Formation of Advanced Glycation End Products During Inflammation

Melissa M. Anderson; Jay W. Heinecke

Abstract

View articletitled, Production of Nε-(Carboxymethyl)Lysine Is Impaired in Mice Deficient in NADPH Oxidase: A Role for Phagocyte-Derived Oxidants in the Formation of Advanced Glycation End Products During Inflammation

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Topics: lysine , mice , nadph oxidases , neutrophils , oxidants

Diabetes August 2003, Vol.52, 2137-2143. doi:https://doi.org/10.2337/diabetes.52.8.2137

Expression of Constitutively Active cGMP-Dependent Protein Kinase Prevents Glucose Stimulation of Thrombospondin 1 Expression and TGF-β Activity

Shuxia Wang; Xing Wu; Thomas M. Lincoln; Joanne E. Murphy-Ullrich

Abstract

View articletitled, Expression of Constitutively Active cGMP-Dependent Protein Kinase Prevents Glucose Stimulation of Thrombospondin 1 Expression and TGF-β Activity

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Topics: catalytic domain , glucose , tetracycline , thrombospondin 1 , cyclic gmp

Diabetes August 2003, Vol.52, 2144-2150. doi:https://doi.org/10.2337/diabetes.52.8.2144

Genetics

Microarray Analysis of Gene Expression in the Kidneys of New- and Post-Onset Diabetic NOD Mice

Karen H.S. Wilson; Sarah E. Eckenrode; Quan-Zhen Li; Qing-Guo Ruan; Ping Yang; Jing-Da Shi; Abdoreza Davoodi-Semiromi; Richard A. McIndoe; Byron P. Croker; Jin-Xiong She

Abstracts

View articletitled, Microarray Analysis of Gene Expression in the Kidneys of New- and Post-Onset Diabetic NOD Mice

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Topics: dna, complementary , gene expression , kidney , mice, inbred nod , mice

Diabetes August 2003, Vol.52, 2151-2159. doi:https://doi.org/10.2337/diabetes.52.8.2151

Prevalence and Characteristics of the Metabolic Syndrome in the San Antonio Heart and Framingham Offspring Studies

James B. Meigs; Peter W.F. Wilson; David M. Nathan; Ralph B. D’Agostino, Sr.; Ken Williams; Steven M. Haffner

Abstract

View articletitled, Prevalence and Characteristics of the Metabolic Syndrome in the San Antonio Heart and Framingham Offspring Studies

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Topics: adult treatment panel iii , framingham heart study , heart , insulin resistance , metabolic syndrome x

Diabetes August 2003, Vol.52, 2160-2167. doi:https://doi.org/10.2337/diabetes.52.8.2160

Minimal Model-Based Insulin Sensitivity Has Greater Heritability and a Different Genetic Basis Than Homeostasis Model Assessment or Fasting Insulin

Richard N. Bergman; Daniel J. Zaccaro; Richard M. Watanabe; Steven M. Haffner; Mohammed F. Saad; Jill M. Norris; Lynne E. Wagenknecht; James E. Hokanson; Jerome I. Rotter; Steven S. Rich

Abstract

View articletitled, Minimal Model-Based Insulin Sensitivity Has Greater Heritability and a Different Genetic Basis Than Homeostasis Model Assessment or Fasting Insulin

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Topics: fasting , genetics , insulin , insulin resistance , insulin sensitivity

Diabetes August 2003, Vol.52, 2168-2174. doi:https://doi.org/10.2337/diabetes.52.8.2168

Identification of Epistatic Interaction Involved in Obesity Using the KK/Ta Mouse as a Type 2 Diabetes Model: Is Zn-α₂ Glycoprotein-1 a Candidate Gene for Obesity?

Tomohito Gohda; Yuichiro Makita; Toshihide Shike; Mitsuo Tanimoto; Kazuhiko Funabiki; Satoshi Horikoshi; Yasuhiko Tomino

Abstract

View articletitled, Identification of Epistatic Interaction Involved in Obesity Using the KK/Ta Mouse as a Type 2 Diabetes Model: Is Zn-α2 Glycoprotein-1 a Candidate Gene for Obesity?

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Topics: adiponectin , diabetes mellitus, type 2 , glycoproteins , mice , obesity

Diabetes August 2003, Vol.52, 2175-2181. doi:https://doi.org/10.2337/diabetes.52.8.2175

Brief Genetics Report

Genetic Modifiers of the Age at Diagnosis of Diabetes (MODY3) in Carriers of Hepatocyte Nuclear Factor-1α Mutations Map to Chromosomes 5p15, 9q22, and 14q24

Sung-Hoon Kim; Xiaowei Ma; Tomasz Klupa; Christine Powers; Marcus Pezzolesi; James H. Warram; Stephen S. Rich; Andrzej S. Krolewski; Alessandro Doria

Abstracts

View articletitled, Genetic Modifiers of the Age at Diagnosis of Diabetes (MODY3) in Carriers of Hepatocyte Nuclear Factor-1α Mutations Map to Chromosomes 5p15, 9q22, and 14q24

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Topics: chromosomes , genetic linkage analysis , genetics , genome , genotype determination

Diabetes August 2003, Vol.52, 2182-2186. doi:https://doi.org/10.2337/diabetes.52.8.2182

Issues

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Signal Transduction

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Islet

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Genetics

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