Skip Nav Destination
Issues
1 January 2004
ISSN 0012-1797
EISSN 1939-327X
Rapid Publication
Transmission of Maternal Islet Antibodies and Risk of Autoimmune Diabetes in Offspring of Mothers With Type 1 Diabetes
Topics:
antibodies
,
autoantibodies
,
diabetes mellitus, type 1
,
autoimmunity
,
generalized anxiety disorder
Diabetes January 2004, Vol.53, 1-4. doi:https://doi.org/10.2337/diabetes.53.1.1
Perspectives in Diabetes
Epac: A New cAMP-Binding Protein in Support of Glucagon-Like Peptide-1 Receptor-Mediated Signal Transduction in the Pancreatic β-Cell
Topics:
cyclic amp
,
exocytosis
,
glucagon-like peptide 1
,
signal transduction
,
insulin secretion
Diabetes January 2004, Vol.53, 5-13. doi:https://doi.org/10.2337/diabetes.53.1.5
Metabolism
Portal Serotonin Infusion and Glucose Disposal in Conscious Dogs
Topics:
glucose
,
infusion procedures
,
serotonin
,
dog, domestic
,
glucagon
Diabetes January 2004, Vol.53, 14-20. doi:https://doi.org/10.2337/diabetes.53.1.14
Exercise-Induced Protein Kinase C Isoform-Specific Activation in Human Skeletal Muscle
Topics:
cytosol
,
phosphorylation
,
protein isoforms
,
protein kinase c
,
skeletal muscles
Diabetes January 2004, Vol.53, 21-24. doi:https://doi.org/10.2337/diabetes.53.1.21
Ceramide Content Is Increased in Skeletal Muscle From Obese Insulin-Resistant Humans
John M. Adams, II; Thongchai Pratipanawatr; Rachele Berria; Elaine Wang; Ralph A. DeFronzo; M. Cameron Sullards; Lawrence J. Mandarino
Topics:
ceramides
,
insulin
,
obesity
,
phosphorylation
,
proto-oncogene proteins c-akt
Diabetes January 2004, Vol.53, 25-31. doi:https://doi.org/10.2337/diabetes.53.1.25
Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog
Mary Courtney Moore; Shosuke Satake; Margaret Lautz; Scott A. Soleimanpour; Doss W. Neal; Marta Smith; Alan D. Cherrington
Topics:
dog, domestic
,
glucose
,
nonesterified fatty acids
,
insulin
,
glycerol
Diabetes January 2004, Vol.53, 32-40. doi:https://doi.org/10.2337/diabetes.53.1.32
Signal Transduction
Dehydroepiandrosterone Stimulates Glucose Uptake in Human and Murine Adipocytes by Inducing GLUT1 and GLUT4 Translocation to the Plasma Membrane
Sebastio Perrini; Annalisa Natalicchio; Luigi Laviola; Gaetana Belsanti; Carmela Montrone; Angelo Cignarelli; Vincenza Minielli; Maria Grano; Giovanni De Pergola; Riccardo Giorgino; Francesco Giorgino
Topics:
adipocytes
,
dehydroepiandrosterone
,
insulin
,
glucose transport
,
translocation (genetics)
Diabetes January 2004, Vol.53, 41-52. doi:https://doi.org/10.2337/diabetes.53.1.41
PKCα Is Activated But Not Required During Glucose-Induced Insulin Secretion From Rat Pancreatic Islets
Lee Carpenter; Christopher J. Mitchell; Zheng Z. Xu; Philip Poronnik; Gerald W. Both; Trevor J. Biden
Topics:
adenoviruses
,
glucose
,
insulin secretion
,
endocrine pancreas
,
phosphotransferases
Diabetes January 2004, Vol.53, 53-60. doi:https://doi.org/10.2337/diabetes.53.1.53
Islet-Sparing Effects of Protein Tyrosine Phosphatase-1b Deficiency Delays Onset of Diabetes in IRS2 Knockout Mice
Jake A. Kushner; Fawaz G. Haj; Lori D. Klaman; Matthew A. Dow; Barbara B. Kahn; Benjamin G. Neel; Morris F. White
Topics:
insulin
,
irs2 protein, human
,
mice
,
tyrosine
,
phosphoric monoester hydrolases
Diabetes January 2004, Vol.53, 61-66. doi:https://doi.org/10.2337/diabetes.53.1.61
Metabolic Pathways That Mediate Inhibition of Hypothalamic Neurons by Glucose
Topics:
glucose
,
neurons
,
hypothalamus
Diabetes January 2004, Vol.53, 67-73. doi:https://doi.org/10.2337/diabetes.53.1.67
Stimulation of Lipolysis by Tumor Necrosis Factor-α in 3T3-L1 Adipocytes Is Glucose Dependent: Implications for Long-Term Regulation of Lipolysis
Topics:
adipocytes
,
glucose
,
lipolysis
,
tumor necrosis factors
,
lactates
Diabetes January 2004, Vol.53, 74-81. doi:https://doi.org/10.2337/diabetes.53.1.74
Obesity Studies
Responsiveness to Peripherally Administered Melanocortins in Lean and Obese Mice
Susann Blüher; Mary Ziotopoulou; John W. Bullen, Jr; Stergios J. Moschos; Linda Ungsunan; Efi Kokkotou; Eleftheria Maratos-Flier; Christos S. Mantzoros
Topics:
leptin
,
mice
,
mice, inbred c57bl
,
rna, messenger
,
obesity
Diabetes January 2004, Vol.53, 82-90. doi:https://doi.org/10.2337/diabetes.53.1.82
Immunology and Transplantation
Recruitment of Bone Marrow-Derived Endothelial Cells to Sites of Pancreatic β-Cell Injury
Topics:
donors
,
pancreas
,
streptozocin
,
transplantation
,
bone marrow cells
Diabetes January 2004, Vol.53, 91-98. doi:https://doi.org/10.2337/diabetes.53.1.91
Caspase-1 Is Not Required for Type 1 Diabetes in the NOD Mouse
William H. Schott; Bradford D. Haskell; Hubert M. Tse; Martha J. Milton; Jon D. Piganelli; Caroline Morgane Choisy-Rossi; Peter C. Reifsnyder; Alexander V. Chervonsky; Edward H. Leiter
Topics:
caspase-1
,
interleukin-18
,
macrophages
,
mice
,
mice, inbred nod
Diabetes January 2004, Vol.53, 99-104. doi:https://doi.org/10.2337/diabetes.53.1.99
Transplantation of Reversibly Immortalized Insulin-Secreting Human Hepatocytes Controls Diabetes in Pancreatectomized Pigs
Teru Okitsu; Naoya Kobayashi; Hee-Sook Jun; Seungjin Shin; Su-Jin Kim; Jaeseok Han; Hyokjoon Kwon; Masakiyo Sakaguchi; Toshinori Totsugawa; Michinori Kohara; Karen A. Westerman; Noriaki Tanaka; Philippe Leboulch; Ji-Won Yoon
Topics:
hepatocytes
,
insulin
,
suidae
,
glucose
,
transplantation
Diabetes January 2004, Vol.53, 105-112. doi:https://doi.org/10.2337/diabetes.53.1.105
IL-1 Receptor Deficiency Slows Progression to Diabetes in the NOD Mouse
Helen E. Thomas; Windy Irawaty; Rima Darwiche; Thomas C. Brodnicki; Pere Santamaria; Janette Allison; Thomas W.H. Kay
Topics:
cytokine
,
interleukin-1
,
mice
,
mice, inbred nod
,
tumor necrosis factors
Diabetes January 2004, Vol.53, 113-121. doi:https://doi.org/10.2337/diabetes.53.1.113
Islet Studies
Inhibition of Lipase Activity and Lipolysis in Rat Islets Reduces Insulin Secretion
Topics:
adipocytes
,
glucose
,
insulin secretion
,
lipase
,
lipolysis
Diabetes January 2004, Vol.53, 122-128. doi:https://doi.org/10.2337/diabetes.53.1.122
Gene and Protein Kinase Expression Profiling of Reactive Oxygen Species-Associated Lipotoxicity in the Pancreatic β-Cell Line MIN6
Xiaolin Wang; Hui Li; Domenica De Leo; Wanbei Guo; Vasilij Koshkin; I. George Fantus; Adria Giacca; Catherine B. Chan; Sandy Der; Michael B. Wheeler
Topics:
gene expression profiling
,
genes
,
glucose
,
insulin
,
insulin secretion
Diabetes January 2004, Vol.53, 129-140. doi:https://doi.org/10.2337/diabetes.53.1.129
Role of β-Cell Prohormone Convertase (PC)1/3 in Processing of Pro-Islet Amyloid Polypeptide
Lucy Marzban; Genny Trigo-Gonzalez; Xiaorong Zhu; Christopher J. Rhodes; Philippe A. Halban; Donald F. Steiner; C. Bruce Verchere
Topics:
adenoviruses
,
amyloid
,
cytokinesis
,
iapp gene
,
immune sera
Diabetes January 2004, Vol.53, 141-148. doi:https://doi.org/10.2337/diabetes.53.1.141
Induction of β-Cell Proliferation and Retinoblastoma Protein Phosphorylation in Rat and Human Islets Using Adenovirus-Mediated Transfer of Cyclin-Dependent Kinase-4 and Cyclin D1
Topics:
cyclin d1
,
retinoblastoma protein
,
adenoviruses
,
insulin
Diabetes January 2004, Vol.53, 149-159. doi:https://doi.org/10.2337/diabetes.53.1.149
Pathophysiology
Mode of Onset of Type 2 Diabetes from Normal or Impaired Glucose Tolerance
Ele Ferrannini; Monica Nannipieri; Ken Williams; Clicerio Gonzales; Steve M. Haffner; Michael P. Stern
Topics:
deuterium
,
diabetes mellitus, type 2
,
fasting
,
follow-up
,
glucose
Diabetes January 2004, Vol.53, 160-165. doi:https://doi.org/10.2337/diabetes.53.1.160
Complications
Long-Term Renal Effects of a Neutralizing RAGE Antibody in Obese Type 2 Diabetic Mice
Allan Flyvbjerg; Larry Denner; Bieke F. Schrijvers; Ronald G. Tilton; Trine H. Mogensen; Søren R. Paludan; Ruth Rasch
Topics:
antibodies
,
kidney
,
mice
,
rage
,
kidney glomerulus
Diabetes January 2004, Vol.53, 166-172. doi:https://doi.org/10.2337/diabetes.53.1.166
Regulation of the Early Subnormal Retinal Oxygenation Response in Experimental Diabetes by Inducible Nitric Oxide Synthase
Bruce A. Berkowitz; Hongmei Luan; Rita R. Gupta; Daniel Pacheco; Andres Seidner; Robin Roberts; Jessica Liggett; Deborah L. Knoerzer; Jane R. Connor; Yunpeng Du; Timothy S. Kern; Yasuki Ito
Topics:
alveolar ventilation function
,
cell respiration
,
diabetes mellitus, experimental
,
magnetic resonance imaging
,
mice
Diabetes January 2004, Vol.53, 173-178. doi:https://doi.org/10.2337/diabetes.53.1.173
Retinal Vessel Diameters and the Incidence of Gross Proteinuria and Renal Insufficiency in People With Type 1 Diabetes
Topics:
diabetes mellitus, type 1
,
kidney failure
,
proteinuria
,
retinal vessels
,
retinal diseases
Diabetes January 2004, Vol.53, 179-184. doi:https://doi.org/10.2337/diabetes.53.1.179
Elevated Mitochondrial Cytochrome P450 2E1 and Glutathione S-Transferase A4-4 in Streptozotocin-Induced Diabetic Rats: Tissue-Specific Variations and Roles in Oxidative Stress
Topics:
cytochrome p-450 cyp2e1
,
mitochondria
,
oxidative stress
,
streptozocin
,
rats
Diabetes January 2004, Vol.53, 185-194. doi:https://doi.org/10.2337/diabetes.53.1.185
Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes
Cindy J.M. Loomans; Eelco J.P. de Koning; Frank J.T. Staal; Maarten B. Rookmaaker; Caroline Verseyden; Hetty C. de Boer; Marianne C. Verhaar; Branko Braam; Ton J. Rabelink; Anton-Jan van Zonneveld
Topics:
angiogenesis
,
diabetes mellitus, type 1
,
endothelial progenitor cells
,
hemoglobin a, glycosylated
,
vascular complications
Diabetes January 2004, Vol.53, 195-199. doi:https://doi.org/10.2337/diabetes.53.1.195
Peroxisome Proliferator-Activated Receptor-γ Ligands Inhibit TGF-β1-Induced Fibronectin Expression in Glomerular Mesangial Cells
Topics:
fibronectins
,
ligands
,
mesangial cells
,
peroxisome proliferator-activated receptors
,
pioglitazone
Diabetes January 2004, Vol.53, 200-208. doi:https://doi.org/10.2337/diabetes.53.1.200
Genetics
Genetic Variation at the Adiponectin Locus and Risk of Type 2 Diabetes in Women
Frank B. Hu; Alessandro Doria; Tricia Li; James B. Meigs; Simin Liu; Asli Memisoglu; David Hunter; JoAnn E. Manson
Topics:
adiponectin
,
diabetes mellitus, type 2
,
obesity
,
single nucleotide polymorphism
,
haplotypes
Diabetes January 2004, Vol.53, 209-213. doi:https://doi.org/10.2337/diabetes.53.1.209
Lipoprotein Lipase Is a Gene for Insulin Resistance in Mexican Americans
Mark O. Goodarzi; Xiuqing Guo; Kent D. Taylor; Manuel J. Quiñones; Mohammad F. Saad; Huiying Yang; Willa A. Hsueh; Jerome I. Rotter
Topics:
fasting
,
haplotypes
,
insulin
,
insulin resistance
,
insulin sensitivity
Diabetes January 2004, Vol.53, 214-220. doi:https://doi.org/10.2337/diabetes.53.1.214
Familial Hyperinsulinemic Hypoglycemia Caused by a Defect in the SCHAD Enzyme of Mitochondrial Fatty Acid Oxidation
Anders Molven; Guri E. Matre; Marinus Duran; Ronald J. Wanders; Unni Rishaug; Pål R. Njølstad; Egil Jellum; Oddmund Søvik
Topics:
coenzyme a
,
enzymes
,
fatty acid oxidation
,
genes
,
homozygote
Diabetes January 2004, Vol.53, 221-227. doi:https://doi.org/10.2337/diabetes.53.1.221
Genome-Wide Search for Type 2 Diabetes/Impaired Glucose Homeostasis Susceptibility Genes in the Chinese: Significant Linkage to Chromosome 6q21-q23 and Chromosome 1q21-q24
Kunsan Xiang; Yanqing Wang; Taishan Zheng; Weiping Jia; Jie Li; Lei Chen; Kunxue Shen; Songhua Wu; Xin Lin; Guodong Zhang; Congrong Wang; Suijun Wang; Huijuan Lu; Qichen Fang; Yi Shi; Rong Zhang; Jing Xu; Qin Weng
Topics:
chromosomes
,
diabetes mellitus, type 2
,
genes
,
genetic linkage analysis
,
genetic pedigree
Diabetes January 2004, Vol.53, 228-234. doi:https://doi.org/10.2337/diabetes.53.1.228
Brief Genetics Report
The Common −866 G/A Polymorphism in the Promoter of Uncoupling Protein 2 Is Associated With Increased Carbohydrate and Decreased Lipid Oxidation in Juvenile Obesity
Topics:
carbohydrates
,
child
,
childhood obesity
,
glucose
,
lipids
Diabetes January 2004, Vol.53, 235-239. doi:https://doi.org/10.2337/diabetes.53.1.235
Distinguishing Covariation From Causation in Diabetes: A Lesson From the Protein Disulfide Isomerase mRNA Abundance Trait
Topics:
mice
,
rna, messenger
,
protein disulfide isomerase
,
dna, complementary
Diabetes January 2004, Vol.53, 240-244. doi:https://doi.org/10.2337/diabetes.53.1.240
Identification of Major Quantitative Trait Loci Controlling Body Weight Variation in ob/ob Mice
Jonathan P. Stoehr; Jessica E. Byers; Susanne M. Clee; Hong Lan; Igor V. Boronenkov; Kathryn L. Schueler; Brian S. Yandell; Alan D. Attie
Topics:
mice
,
obesity
,
quantitative trait loci
Diabetes January 2004, Vol.53, 245-249. doi:https://doi.org/10.2337/diabetes.53.1.245
ADA Workshop Report
C-Peptide Is the Appropriate Outcome Measure for Type 1 Diabetes Clinical Trials to Preserve β-Cell Function : Report of an ADA Workshop, 21–22 October 2001
Jerry P. Palmer; G. Alexander Fleming; Carla J. Greenbaum; Kevan C. Herold; Lisa D. Jansa; Hubert Kolb; John M. Lachin; Kenneth S. Polonsky; Paolo Pozzilli; Jay S. Skyler; Michael W. Steffes
Topics:
c-peptide
,
diabetes mellitus, type 1
,
insulin
,
dcct trial
,
hemoglobin a, glycosylated
Diabetes January 2004, Vol.53, 250-264. doi:https://doi.org/10.2337/diabetes.53.1.250
