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Issues
1 May 2004
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Genetic Studies of the Etiology of Type 2 Diabetes in Pima Indians: Hunting for Pieces to a Complicated Puzzle
Diabetes May 2004, Vol.53, 1181-1186. doi:https://doi.org/10.2337/diabetes.53.5.1181
Metabolism
One Week’s Treatment With the Long-Acting Glucagon-Like Peptide 1 Derivative Liraglutide (NN2211) Markedly Improves 24-h Glycemia and α- and β-Cell Function and Reduces Endogenous Glucose Release in Patients with Type 2 Diabetes
Kristine B. Degn; Claus B. Juhl; Jeppe Sturis; Grethe Jakobsen; Birgitte Brock; Visvanathan Chandramouli; Joergen Rungby; Bernard R. Landau; Ole Schmitz
Diabetes May 2004, Vol.53, 1187-1194. doi:https://doi.org/10.2337/diabetes.53.5.1187
Evaluation of Insulin Sensitivity and β-Cell Function Indexes Obtained From Minimal Model Analysis of a Meal Tolerance Test
Garry M. Steil; Chi-min Hwu; Robert Janowski; Farzam Hariri; Sujata Jinagouda; Christine Darwin; Sameh Tadros; Kerstin Rebrin; Mohammed F. Saad
Diabetes May 2004, Vol.53, 1201-1207. doi:https://doi.org/10.2337/diabetes.53.5.1201
Signal Transduction
Exercise and Myocyte Enhancer Factor 2 Regulation in Human Skeletal Muscle
Diabetes May 2004, Vol.53, 1208-1214. doi:https://doi.org/10.2337/diabetes.53.5.1208
Relationship Between Insulin Sensitivity and Sphingomyelin Signaling Pathway in Human Skeletal Muscle
Marek Straczkowski; Irina Kowalska; Agnieszka Nikolajuk; Stella Dzienis-Straczkowska; Ida Kinalska; Marcin Baranowski; Malgorzata Zendzian-Piotrowska; Zofia Brzezinska; Jan Gorski
Diabetes May 2004, Vol.53, 1215-1221. doi:https://doi.org/10.2337/diabetes.53.5.1215
Third Ventricular Alloxan Reversibly Impairs Glucose Counterregulatory Responses
Diabetes May 2004, Vol.53, 1230-1236. doi:https://doi.org/10.2337/diabetes.53.5.1230
Obesity Study
Effects of Diabetes and Insulin on the Expression of Galanin-Like Peptide in the Hypothalamus of the Rat
Gregory S. Fraley; Jarrad M. Scarlett; Issei Shimada; Dawit N. Teklemichael; Blake V. Acohido; Donald K. Clifton; Robert A. Steiner
Diabetes May 2004, Vol.53, 1237-1242. doi:https://doi.org/10.2337/diabetes.53.5.1237
Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ
Knut Tomas Dalen; Kristina Schoonjans; Stine M. Ulven; Mina Susanne Weedon-Fekjaer; Trine Gjesti Bentzen; Hana Koutnikova; Johan Auwerx; Hilde I. Nebb
Diabetes May 2004, Vol.53, 1243-1252. doi:https://doi.org/10.2337/diabetes.53.5.1243
Triglycerides Induce Leptin Resistance at the Blood-Brain Barrier
William A. Banks; Alan B. Coon; Sandra M. Robinson; Asif Moinuddin; Jessica M. Shultz; Ryota Nakaoke; John E. Morley
Diabetes May 2004, Vol.53, 1253-1260. doi:https://doi.org/10.2337/diabetes.53.5.1253
Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation
Alex W. Cohen; Babak Razani; William Schubert; Terence M. Williams; Xiao Bo Wang; Puneeth Iyengar; Dawn L. Brasaemle; Philipp E. Scherer; Michael P. Lisanti
Diabetes May 2004, Vol.53, 1261-1270. doi:https://doi.org/10.2337/diabetes.53.5.1261
Effects of Dietary Monosaccharides on Sympathetic Nervous System Activity in Adipose Tissues of Male Rats
Diabetes May 2004, Vol.53, 1271-1278. doi:https://doi.org/10.2337/diabetes.53.5.1271
High Serum Resistin Is Associated With an Increase in Adiposity But Not a Worsening of Insulin Resistance in Pima Indians
Diabetes May 2004, Vol.53, 1279-1284. doi:https://doi.org/10.2337/diabetes.53.5.1279
From Blood Monocytes to Adipose Tissue-Resident Macrophages: Induction of Diapedesis by Human Mature Adipocytes
Cyrile A. Curat; Alexandra Miranville; Coralie Sengenès; Michael Diehl; Carolin Tonus; Rudi Busse; Anne Bouloumié
Diabetes May 2004, Vol.53, 1285-1292. doi:https://doi.org/10.2337/diabetes.53.5.1285
Immunology and Transplantation
Islet Cell Autoimmunity in a Triethnic Adult Population of the Third National Health and Nutrition Examination Survey
Emma Barinas-Mitchell; Susan Pietropaolo; Ying-Jian Zhang; Tyona Henderson; Massimo Trucco; Lewis H. Kuller; Massimo Pietropaolo
Diabetes May 2004, Vol.53, 1293-1302. doi:https://doi.org/10.2337/diabetes.53.5.1293
Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function
Ravi Bhargava; Peter A. Senior; Thomas E. Ackerman; Edmond A. Ryan; Breay W. Paty; Jonathan R.T. Lakey; A.M. James Shapiro
Diabetes May 2004, Vol.53, 1311-1317. doi:https://doi.org/10.2337/diabetes.53.5.1311
Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets
Marcela Brissova; Michael Fowler; Peter Wiebe; Alena Shostak; Masakazu Shiota; Aramandla Radhika; P. Charles Lin; Maureen Gannon; Alvin C. Powers
Diabetes May 2004, Vol.53, 1318-1325. doi:https://doi.org/10.2337/diabetes.53.5.1318
Islet Study
Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors
Tanya Hansotia; Laurie L. Baggio; Dominique Delmeire; Simon A. Hinke; Yuichiro Yamada; Katsushi Tsukiyama; Yutaka Seino; Jens J. Holst; Frans Schuit; D.J. Drucker
Diabetes May 2004, Vol.53, 1326-1335. doi:https://doi.org/10.2337/diabetes.53.5.1326
Pathophysiology
Catalase Protects Cardiomyocyte Function in Models of Type 1 and Type 2 Diabetes
Gang Ye; Naira S. Metreveli; Rajakumar V. Donthi; Shen Xia; Ming Xu; Edward C. Carlson; Paul N. Epstein
Diabetes May 2004, Vol.53, 1336-1343. doi:https://doi.org/10.2337/diabetes.53.5.1336
Complication
Insulin Generates Free Radicals by an NAD(P)H, Phosphatidylinositol 3′-Kinase-Dependent Mechanism in Human Skin Fibroblasts Ex Vivo
Giulio Ceolotto; Michela Bevilacqua; Italia Papparella; Elisabetta Baritono; Lorenzo Franco; Carlo Corvaja; Martina Mazzoni; Andrea Semplicini; Angelo Avogaro
Diabetes May 2004, Vol.53, 1344-1351. doi:https://doi.org/10.2337/diabetes.53.5.1344
Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C
Diabetes May 2004, Vol.53, 1352-1359. doi:https://doi.org/10.2337/diabetes.53.5.1352
Genetics
Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region
Jose C. Florez; Noël Burtt; Paul I.W. de Bakker; Peter Almgren; Tiinamaija Tuomi; Johan Holmkvist; Daniel Gaudet; Thomas J. Hudson; Steve F. Schaffner; Mark J. Daly; Joel N. Hirschhorn; Leif Groop; David Altshuler
Diabetes May 2004, Vol.53, 1360-1368. doi:https://doi.org/10.2337/diabetes.53.5.1360
Genome-Wide Scans Reveal Quantitative Trait Loci on 8p and 13q Related to Insulin Action and Glucose Metabolism: The San Antonio Family Heart Study
Guowen Cai; Shelley A. Cole; Jeanne H. Freeland-Graves; Jean W. MacCluer; John Blangero; Anthony G. Comuzzie
Diabetes May 2004, Vol.53, 1369-1374. doi:https://doi.org/10.2337/diabetes.53.5.1369
Identification of a Locus for Maturity-Onset Diabetes of the Young on Chromosome 8p23
Sung-Hoon Kim; Xiaowei Ma; Stanislawa Weremowicz; Tonino Ercolino; Christine Powers; Wojciech Mlynarski; K. Aviva Bashan; James H. Warram; Josyf Mychaleckyj; Stephen S. Rich; Andrzej S. Krolewski; Alessandro Doria
Diabetes May 2004, Vol.53, 1375-1384. doi:https://doi.org/10.2337/diabetes.53.5.1375
Complex Haplotypes of the PGC-1α Gene Are Associated With Carbohydrate Metabolism and Type 2 Diabetes
Hannes Oberkofler; Veronika Linnemayr; Raimund Weitgasser; Kerstin Klein; Mingqiang Xie; Bernhard Iglseder; Franz Krempler; Bernhard Paulweber; Wolfgang Patsch
Diabetes May 2004, Vol.53, 1385-1393. doi:https://doi.org/10.2337/diabetes.53.5.1385
Brief Genetics Report
Investigation of the Human ANP Gene in Type 1 Diabetic Nephropathy: Case-Control and Follow-up Studies
Diabetes May 2004, Vol.53, 1394-1398. doi:https://doi.org/10.2337/diabetes.53.5.1394
Letter to the Editor
Status of Research Funding by the American Diabetes Association—5th and Final Year
Diabetes May 2004, Vol.53, 1403. doi:https://doi.org/10.2337/diabetes.53.5.1403