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Issues
1 June 2004
ISSN 0012-1797
EISSN 1939-327X
Rapid Publication
Human Pancreatic Duct Cells Exert Tissue Factor-Dependent Procoagulant Activity : Relevance to Islet Transplantation
Claire Beuneu; Olivier Vosters; Babak Movahedi; Myriam Remmelink; Isabelle Salmon; Daniel Pipeleers; Olivier Pradier; Michel Goldman; Valérie Verhasselt
Diabetes June 2004, Vol.53, 1407-1411. doi:https://doi.org/10.2337/diabetes.53.6.1407
Perspective in Diabetes
Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes
Diabetes June 2004, Vol.53, 1412-1417. doi:https://doi.org/10.2337/diabetes.53.6.1412
Metabolism
Microvascular Recruitment Is an Early Insulin Effect That Regulates Skeletal Muscle Glucose Uptake In Vivo
Michelle A. Vincent; Lucy H. Clerk; Jonathan R. Lindner; Alexander L. Klibanov; Michael G. Clark; Stephen Rattigan; Eugene J. Barrett
Diabetes June 2004, Vol.53, 1418-1423. doi:https://doi.org/10.2337/diabetes.53.6.1418
Signal Transduction
AMP Kinase-Induced Skeletal Muscle Glucose But Not Long-Chain Fatty Acid Uptake Is Dependent on Nitric Oxide
Jane Shearer; Patrick T. Fueger; Brittney Vorndick; Deanna P. Bracy; Jeffery N. Rottman; Jeffery A. Clanton; David H. Wasserman
Diabetes June 2004, Vol.53, 1429-1435. doi:https://doi.org/10.2337/diabetes.53.6.1429
Role of Adipocyte-Derived Factors in Enhancing Insulin Signaling in Skeletal Muscle and White Adipose Tissue of Mice Lacking Acyl CoA:Diacylglycerol Acyltransferase 1
Hubert C. Chen; Meghana Rao; Mini P. Sajan; Mary Standaert; Yoshinori Kanoh; Atsushi Miura; Robert V. Farese, Jr.; Robert V. Farese
Diabetes June 2004, Vol.53, 1445-1451. doi:https://doi.org/10.2337/diabetes.53.6.1445
Immunology and Transplantation
Advanced Glycation End Products Modulate the Maturation and Function of Peripheral Blood Dendritic Cells
Diabetes June 2004, Vol.53, 1452-1458. doi:https://doi.org/10.2337/diabetes.53.6.1452
Tracking the Recruitment of Diabetogenic CD8+ T-Cells to the Pancreas in Real Time
Diabetes June 2004, Vol.53, 1459-1466. doi:https://doi.org/10.2337/diabetes.53.6.1459
Islet Study
Changes in the Dimeric State of Neuronal Nitric Oxide Synthase Affect the Kinetics of Secretagogue-Induced Insulin Response
Anne-Dominique Lajoix; Martine Pugnière; Françoise Roquet; Jean-Claude Mani; Samuel Dietz; Nathalie Linck; Fleur Faurie; Gérard Ribes; Pierre Petit; René Gross
Diabetes June 2004, Vol.53, 1467-1474. doi:https://doi.org/10.2337/diabetes.53.6.1467
The Role of Calcium/Calmodulin-Dependent Protein Kinase Cascade in Glucose Upregulation of Insulin Gene Expression
Xiao Yu; Koji Murao; Yoshitaka Sayo; Hitomi Imachi; Wen M. Cao; Shouji Ohtsuka; Michio Niimi; Hiroshi Tokumitsu; Hiroyuki Inuzuka; Norman C.W. Wong; Ryoji Kobayashi; Toshihiko Ishida
Diabetes June 2004, Vol.53, 1475-1481. doi:https://doi.org/10.2337/diabetes.53.6.1475
Regulation of α-Cell Function by the β-Cell in Isolated Human and Rat Islets Deprived of Glucose: the “Switch-off” Hypothesis
Diabetes June 2004, Vol.53, 1488-1495. doi:https://doi.org/10.2337/diabetes.53.6.1488
Glucose and Insulin Treatment of Insulinoma Cells Results in Transcriptional Regulation of a Common Set of Genes
Mitsuru Ohsugi; Corentin Cras-Méneur; Yiyong Zhou; Wesley Warren; Ernesto Bernal-Mizrachi; M. Alan Permutt
Diabetes June 2004, Vol.53, 1496-1508. doi:https://doi.org/10.2337/diabetes.53.6.1496
Diabetes Due to a Progressive Defect in β-Cell Mass in Rats Transgenic for Human Islet Amyloid Polypeptide (HIP Rat): A New Model for Type 2 Diabetes
Alexandra E. Butler; Jennifer Jang; Tatyana Gurlo; Maynard D. Carty; Walter C. Soeller; Peter C. Butler
Diabetes June 2004, Vol.53, 1509-1516. doi:https://doi.org/10.2337/diabetes.53.6.1509
Islet Secretory Defect in Insulin Receptor Substrate 1 Null Mice Is Linked With Reduced Calcium Signaling and Expression of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2b and -3
Rohit N. Kulkarni; Michael G. Roper; Gabriella Dahlgren; David Q. Shih; Lisa M. Kauri; Jennifer L. Peters; Markus Stoffel; Robert T. Kennedy
Diabetes June 2004, Vol.53, 1517-1525. doi:https://doi.org/10.2337/diabetes.53.6.1517
Regulation of Rat Pancreatic CCKB Receptor and Somatostatin Expression by Insulin
Diabetes June 2004, Vol.53, 1526-1534. doi:https://doi.org/10.2337/diabetes.53.6.1526
Pathophysiology
Influence of Autonomic Neuropathy on QTc Interval Lengthening During Hypoglycemia in Type 1 Diabetes
Stuart P. Lee; Lishan Yeoh; Nigel D. Harris; Catherine M. Davies; Robert T. Robinson; Andrew Leathard; Christopher Newman; Ian A. Macdonald; Simon R. Heller
Diabetes June 2004, Vol.53, 1535-1542. doi:https://doi.org/10.2337/diabetes.53.6.1535
Differences in Insulin Resistance in Nondiabetic Subjects With Isolated Impaired Glucose Tolerance or Isolated Impaired Fasting Glucose
Andreas Festa; Ralph D’Agostino, Jr.; Anthony J.G. Hanley; Andrew J. Karter; Mohammed F. Saad; Steven M. Haffner
Diabetes June 2004, Vol.53, 1549-1555. doi:https://doi.org/10.2337/diabetes.53.6.1549
Complication
Molecular Alterations Underlie Nodal and Paranodal Degeneration in Type 1 Diabetic Neuropathy and Are Prevented by C-Peptide
Diabetes June 2004, Vol.53, 1556-1563. doi:https://doi.org/10.2337/diabetes.53.6.1556
Early Endothelial Dysfunction Severely Impairs Skin Blood Flow Response to Local Pressure Application in Streptozotocin-Induced Diabetic Mice
Dominique Sigaudo-Roussel; Claire Demiot; Bérengère Fromy; Audrey Koïtka; Georges Lefthériotis; Pierre Abraham; Jean Louis Saumet
Diabetes June 2004, Vol.53, 1564-1569. doi:https://doi.org/10.2337/diabetes.53.6.1564
Association Between Mannose-Binding Lectin and Vascular Complications in Type 1 Diabetes
Troels K. Hansen; Lise Tarnow; Steffen Thiel; Rudi Steffensen; Coen D. Stehouwer; Casper G. Schalkwijk; Hans-Henrik Parving; Allan Flyvbjerg
Diabetes June 2004, Vol.53, 1570-1576. doi:https://doi.org/10.2337/diabetes.53.6.1570
Genetics
A New Mouse Model of Type 2 Diabetes, Produced by N-Ethyl-Nitrosourea Mutagenesis, Is the Result of a Missense Mutation in the Glucokinase Gene
Ayo A. Toye; Lee Moir; Alison Hugill; Liz Bentley; Julie Quarterman; Vesna Mijat; Tertius Hough; Michelle Goldsworthy; Alison Haynes; A. Jacqueline Hunter; Mick Browne; Nigel Spurr; Roger D. Cox
Diabetes June 2004, Vol.53, 1577-1583. doi:https://doi.org/10.2337/diabetes.53.6.1577
Interaction and Association Analysis of a Type 1 Diabetes Susceptibility Locus on Chromosome 5q11-q13 and the 7q32 Chromosomal Region in Scandinavian Families
Pernilla Holm; Berit Rydlander; Holger Luthman; Ingrid Kockum; for the European Consortium for IDDM Genome Studies
Diabetes June 2004, Vol.53, 1584-1591. doi:https://doi.org/10.2337/diabetes.53.6.1584
A Novel Syndrome of Autosomal-Dominant Hyperinsulinemic Hypoglycemia Linked to a Mutation in the Human Insulin Receptor Gene
Kurt Højlund; Torben Hansen; Maria Lajer; Jan Erik Henriksen; Klaus Levin; Jörgen Lindholm; Oluf Pedersen; Henning Beck-Nielsen
Diabetes June 2004, Vol.53, 1592-1598. doi:https://doi.org/10.2337/diabetes.53.6.1592
Brief Genetics Report
Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts
Bin Xu; Shi-Quan Hu; Ying-Chi Chu; Shuhua Wang; Run-ying Wang; Satoe H. Nakagawa; Panayotis G. Katsoyannis; Michael A. Weiss
Diabetes June 2004, Vol.53, 1599-1602. doi:https://doi.org/10.2337/diabetes.53.6.1599
Leptin and Leptin Receptor Gene Polymorphisms and Changes in Glucose Homeostasis in Response to Regular Exercise in Nondiabetic Individuals: The HERITAGE Family Study
Timo A. Lakka; Tuomo Rankinen; S. John Weisnagel; Yvon C. Chagnon; Hanna-Maaria Lakka; Olavi Ukkola; Normand Boulé; Treva Rice; Arthur S. Leon; James S. Skinner; Jack H. Wilmore; D.C. Rao; Richard Bergman; Claude Bouchard
Diabetes June 2004, Vol.53, 1603-1608. doi:https://doi.org/10.2337/diabetes.53.6.1603
Genome-wide Scan for Type 2 Diabetes Loci in Hong Kong Chinese and Confirmation of a Susceptibility Locus on Chromosome 1q21-q25
Maggie C.Y. Ng; Wing-Yee So; Nancy J. Cox; Vincent K.L. Lam; Clive S. Cockram; Julian A.J.H. Critchley; Graeme I. Bell; Juliana C.N. Chan
Diabetes June 2004, Vol.53, 1609-1613. doi:https://doi.org/10.2337/diabetes.53.6.1609
Pharmacology and Therapeutics
Lower Within-Subject Variability of Insulin Detemir in Comparison to NPH Insulin and Insulin Glargine in People With Type 1 Diabetes
Tim Heise; Leszek Nosek; Birgitte Biilmann Rønn; Lars Endahl; Lutz Heinemann; Christoph Kapitza; Eberhard Draeger
Diabetes June 2004, Vol.53, 1614-1620. doi:https://doi.org/10.2337/diabetes.53.6.1614