Skip Nav Destination

Issues

Select Decade

Select Year

Issue

Search within issue:

Search within issue

Perspective in Diabetes

Therapeutic Strategies Based on Glucagon-Like Peptide 1

Carolyn F. Deacon

Abstracts

View articletitled, Therapeutic Strategies Based on Glucagon-Like Peptide 1

Open the PDF for in another window

Topics: glucagon-like peptide 1 , glucose , peptides , incretin

Diabetes September 2004, Vol.53, 2181-2189. doi:https://doi.org/10.2337/diabetes.53.9.2181

New Methodology and Database

An Adenovirus Vector for Efficient RNA Interference–Mediated Suppression of Target Genes in Insulinoma Cells and Pancreatic Islets of Langerhans

James R. Bain; Jonathan C. Schisler; Koji Takeuchi; Christopher B. Newgard; Thomas C. Becker

Abstracts

View articletitled, An Adenovirus Vector for Efficient RNA Interference–Mediated Suppression of Target Genes in Insulinoma Cells and Pancreatic Islets of Langerhans

Open the PDF for in another window

Topics: adenoviruses , endocrine pancreas , insulinoma , psychological suppression , rna interference

Diabetes September 2004, Vol.53, 2190-2194. doi:https://doi.org/10.2337/diabetes.53.9.2190

Metabolism

Expression of Adiponectin Receptor mRNA in Human Skeletal Muscle Cells Is Related to In Vivo Parameters of Glucose and Lipid Metabolism

Harald Staiger; Simone Kaltenbach; Katrin Staiger; Norbert Stefan; Andreas Fritsche; Alke Guirguis; Claudia Péterfi; Melanie Weisser; Fausto Machicao; Michael Stumvoll; Hans-Ulrich Häring

Abstracts

View articletitled, Expression of Adiponectin Receptor mRNA in Human Skeletal Muscle Cells Is Related to In Vivo Parameters of Glucose and Lipid Metabolism

Open the PDF for in another window

Topics: receptors, adiponectin , rna, messenger , skeletal myocytes , insulin , oral glucose tolerance test

Diabetes September 2004, Vol.53, 2195-2201. doi:https://doi.org/10.2337/diabetes.53.9.2195

Transcortical Direct Current Potential Shift Reflects Immediate Signaling of Systemic Insulin to the Human Brain

Manfred Hallschmid; Bernd Schultes; Lisa Marshall; Matthias Mölle; Werner Kern; Julia Bredthauer; Horst L. Fehm; Jan Born

Abstract

View articletitled, Transcortical Direct Current Potential Shift Reflects Immediate Signaling of Systemic Insulin to the Human Brain

Open the PDF for in another window

Topics: electroencephalography , hypoglycemia , insulin , insulin administration , subcutaneous insulin delivery

Diabetes September 2004, Vol.53, 2202-2208. doi:https://doi.org/10.2337/diabetes.53.9.2202

CD36 in Myocytes Channels Fatty Acids to a Lipase-Accessible Triglyceride Pool That Is Related to Cell Lipid and Insulin Responsiveness

Claire C. Bastie; Tahar Hajri; Victor A. Drover; Paul A. Grimaldi; Nada A. Abumrad

Abstract

View articletitled, CD36 in Myocytes Channels Fatty Acids to a Lipase-Accessible Triglyceride Pool That Is Related to Cell Lipid and Insulin Responsiveness

Open the PDF for in another window

Topics: cd36 antigens , fatty acids , lipids , palmitates , triglycerides

Diabetes September 2004, Vol.53, 2209-2216. doi:https://doi.org/10.2337/diabetes.53.9.2209

Cholesterol Metabolism in Type 1 Diabetes

Helena Gylling; Juha A. Tuominen; Veikko A. Koivisto; Tatu A. Miettinen

Abstract

View articletitled, Cholesterol Metabolism in Type 1 Diabetes

Open the PDF for in another window

Topics: cholestanol , cholesterol , diabetes mellitus, type 1 , lipoproteins , loudness discomfort level

Diabetes September 2004, Vol.53, 2217-2222. doi:https://doi.org/10.2337/diabetes.53.9.2217

Signal Transduction

Syntaxin 4 Transgenic Mice Exhibit Enhanced Insulin-Mediated Glucose Uptake in Skeletal Muscle

Beth A. Spurlin; So-Young Park; Angela K. Nevins; Jason K. Kim; Debbie C. Thurmond

Abstract

View articletitled, Syntaxin 4 Transgenic Mice Exhibit Enhanced Insulin-Mediated Glucose Uptake in Skeletal Muscle

Open the PDF for in another window

Topics: glucose , glucose uptake , insulin , mice , mice, transgenic

Diabetes September 2004, Vol.53, 2223-2231. doi:https://doi.org/10.2337/diabetes.53.9.2223

Suppressor of Cytokine Signaling 3 Expression and Insulin Resistance in Skeletal Muscle of Obese and Type 2 Diabetic Patients

Jennifer Rieusset; Karim Bouzakri; Emmanuel Chevillotte; Nadège Ricard; Delphine Jacquet; Jean-Philippe Bastard; Martine Laville; Hubert Vidal

Abstract

View articletitled, Suppressor of Cytokine Signaling 3 Expression and Insulin Resistance in Skeletal Muscle of Obese and Type 2 Diabetic Patients

Open the PDF for in another window

Topics: insulin , interleukin-6 , obesity , rna, messenger , suppressor of cytokine signaling 3 protein

Diabetes September 2004, Vol.53, 2232-2241. doi:https://doi.org/10.2337/diabetes.53.9.2232

Induced Adiposity and Adipocyte Hypertrophy in Mice Lacking the AMP-Activated Protein Kinase-α2 Subunit

Josep A. Villena; Benoit Viollet; Fabrizzio Andreelli; Axel Kahn; Sophie Vaulont; Hei Sook Sul

Abstracts

View articletitled, Induced Adiposity and Adipocyte Hypertrophy in Mice Lacking the AMP-Activated Protein Kinase-α2 Subunit

Open the PDF for in another window

Topics: adipocytes , adipose tissue , mice , obesity , triglycerides

Diabetes September 2004, Vol.53, 2242-2249. doi:https://doi.org/10.2337/diabetes.53.9.2242

Obesity Study

Involvement of Hypothalamic Histamine H₁ Receptor in the Regulation of Feeding Rhythm and Obesity

Takayuki Masaki; Seiichi Chiba; Tohru Yasuda; Hitoshi Noguchi; Tetsuya Kakuma; Takeshi Watanabe; Toshiie Sakata; Hironobu Yoshimatsu

Abstract

View articletitled, Involvement of Hypothalamic Histamine H1 Receptor in the Regulation of Feeding Rhythm and Obesity

Open the PDF for in another window

Topics: histamine , hypothalamus , leptin , mice , obesity

Diabetes September 2004, Vol.53, 2250-2260. doi:https://doi.org/10.2337/diabetes.53.9.2250

Increased Serum Leptin Protects From Adiposity Despite the Increased Glucose Uptake in White Adipose Tissue in Mice Lacking p85α Phosphoinositide 3-Kinase

Yasuo Terauchi; Junji Matsui; Junji Kamon; Toshimasa Yamauchi; Naoto Kubota; Kajuro Komeda; Shinichi Aizawa; Yasuo Akanuma; Motowo Tomita; Takashi Kadowaki

Abstract

View articletitled, Increased Serum Leptin Protects From Adiposity Despite the Increased Glucose Uptake in White Adipose Tissue in Mice Lacking p85α Phosphoinositide 3-Kinase

Open the PDF for in another window

Topics: diet , diet, high-fat , leptin , mice , obesity

Diabetes September 2004, Vol.53, 2261-2270. doi:https://doi.org/10.2337/diabetes.53.9.2261

Immunology and Transplantation

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Ewa Gurgul; Stephan Lortz; Markus Tiedge; Anne Jörns; Sigurd Lenzen

Abstract

View articletitled, Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Open the PDF for in another window

Topics: catalase , cytokine , protein overexpression , toxic effect , mitochondria

Diabetes September 2004, Vol.53, 2271-2280. doi:https://doi.org/10.2337/diabetes.53.9.2271

Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Dongmei Han; Xiumin Xu; David Baidal; Jenifer Leith; Camillo Ricordi; Rodolfo Alejandro; Norma S. Kenyon

Abstract

View articletitled, Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Open the PDF for in another window

Topics: allografting , gene expression , therapeutic immunosuppression , insulin , genes

Diabetes September 2004, Vol.53, 2281-2290. doi:https://doi.org/10.2337/diabetes.53.9.2281

Normalization of Multiple Hemostatic Abnormalities in Uremic Type 1 Diabetic Patients After Kidney-Pancreas Transplantation

Paolo Fiorina; Franco Folli; Armando D’Angelo; Giovanna Finzi; Fabio Pellegatta; Valeria Guzzi; Carlo Fedeli; Patrizia Della Valle; Luciana Usellini; Claudia Placidi; Francesco Bifari; Daniela Belloni; Elisabetta Ferrero; Carlo Capella; Antonio Secchi

Abstract

View articletitled, Normalization of Multiple Hemostatic Abnormalities in Uremic Type 1 Diabetic Patients After Kidney-Pancreas Transplantation

Open the PDF for in another window

Topics: blood platelets , hemostatics , kidney , renal and pancreas transplantation , transplantation

Diabetes September 2004, Vol.53, 2291-2300. doi:https://doi.org/10.2337/diabetes.53.9.2291

Peptides From Common Viral and Bacterial Pathogens Can Efficiently Activate Diabetogenic T-Cells

Valeria A. Judkowski; Gina M. Allicotti; Nora Sarvetnick; Clemencia Pinilla

Abstracts

View articletitled, Peptides From Common Viral and Bacterial Pathogens Can Efficiently Activate Diabetogenic T-Cells

Open the PDF for in another window

Topics: peptides , t-lymphocytes , antigens

Diabetes September 2004, Vol.53, 2301-2309. doi:https://doi.org/10.2337/diabetes.53.9.2301

Islet Study

Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model: A Microarray Overview

Michael Matos; Richard Park; Diane Mathis; Christophe Benoist

Abstracts

View articletitled, Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model: A Microarray Overview

Supplementary data

Open the PDF for in another window

Topics: gene expression , genes , cyclophosphamide , endocrine pancreas , chemokines

Diabetes September 2004, Vol.53, 2310-2321. doi:https://doi.org/10.2337/diabetes.53.9.2310

Dissecting the Role of Glucocorticoids on Pancreas Development

Emilie Gesina; François Tronche; Pedro Herrera; Belinda Duchene; Willemène Tales; Paul Czernichow; Bernadette Breant

Abstracts

View articletitled, Dissecting the Role of Glucocorticoids on Pancreas Development

Open the PDF for in another window

Topics: glucocorticoids , pancreas , mice , insulin , transcription factor

Diabetes September 2004, Vol.53, 2322-2329. doi:https://doi.org/10.2337/diabetes.53.9.2322

Identification and Cloning of a β-Cell–Specific Zinc Transporter, ZnT-8, Localized Into Insulin Secretory Granules

Fabrice Chimienti; Séverine Devergnas; Alain Favier; Michel Seve

Abstract

View articletitled, Identification and Cloning of a β-Cell–Specific Zinc Transporter, ZnT-8, Localized Into Insulin Secretory Granules

Open the PDF for in another window

Topics: hela cells , insulin , zinc , zinc transporter , zinc transporter 8

Diabetes September 2004, Vol.53, 2330-2337. doi:https://doi.org/10.2337/diabetes.53.9.2330

Long-Term Islet Graft Survival in NOD Mice by Abrogation of Recurrent Autoimmunity

Qixin Shi; Donghua Wang; Gregg A. Hadley; Adam W. Bingaman; Stephen T. Bartlett; Donna L. Farber

Abstracts

View articletitled, Long-Term Islet Graft Survival in NOD Mice by Abrogation of Recurrent Autoimmunity

Open the PDF for in another window

Topics: antilymphocyte globulin , donors , graft survival , mice , mice, inbred nod

Diabetes September 2004, Vol.53, 2338-2345. doi:https://doi.org/10.2337/diabetes.53.9.2338

Glucokinase Is an Integral Component of the Insulin Granules in Glucose-Responsive Insulin Secretory Cells and Does Not Translocate During Glucose Stimulation

Catherine Arden; Andrew Harbottle; Simone Baltrusch; Markus Tiedge; Loranne Agius

Abstract

View articletitled, Glucokinase Is an Integral Component of the Insulin Granules in Glucose-Responsive Insulin Secretory Cells and Does Not Translocate During Glucose Stimulation

Open the PDF for in another window

Topics: glucokinase , glucose , granules , insulin

Diabetes September 2004, Vol.53, 2346-2352. doi:https://doi.org/10.2337/diabetes.53.9.2346

Pathophysiology

Glucose Intolerance in a Large Cohort of Mediterranean Women With Polycystic Ovary Syndrome: Phenotype and Associated Factors

Alessandra Gambineri; Carla Pelusi; Elisa Manicardi; Valentina Vicennati; Mauro Cacciari; Antonio Maria Morselli-Labate; Uberto Pagotto; Renato Pasquali

Abstract

View articletitled, Glucose Intolerance in a Large Cohort of Mediterranean Women With Polycystic Ovary Syndrome: Phenotype and Associated Factors

Open the PDF for in another window

Topics: diet , insulin , obesity , polycystic ovary syndrome , glucose intolerance

Diabetes September 2004, Vol.53, 2353-2358. doi:https://doi.org/10.2337/diabetes.53.9.2353

Reduced Hepatic Insulin Extraction in Response to Gastric Inhibitory Polypeptide Compensates for Reduced Insulin Secretion in Normal-Weight and Normal Glucose Tolerant First-Degree Relatives of Type 2 Diabetic Patients

Natalia N. Rudovich; Helmut J. Rochlitz; Andreas F.H. Pfeiffer

Abstract

View articletitled, Reduced Hepatic Insulin Extraction in Response to Gastric Inhibitory Polypeptide Compensates for Reduced Insulin Secretion in Normal-Weight and Normal Glucose Tolerant First-Degree Relatives of Type 2 Diabetic Patients

Open the PDF for in another window

Topics: glucose , hyperglycemic agents , insulin , insulin secretion , gastric inhibitory polypeptide

Diabetes September 2004, Vol.53, 2359-2365. doi:https://doi.org/10.2337/diabetes.53.9.2359

Impaired Cardiac Efficiency and Increased Fatty Acid Oxidation in Insulin-Resistant ob/ob Mouse Hearts

Pradip K. Mazumder; Brian T. O’Neill; Matthew W. Roberts; Jonathan Buchanan; Ui Jeong Yun; Robert C. Cooksey; Sihem Boudina; E. Dale Abel

Abstract

View articletitled, Impaired Cardiac Efficiency and Increased Fatty Acid Oxidation in Insulin-Resistant ob/ob Mouse Hearts

Open the PDF for in another window

Topics: heart , insulin , mice , palmitates , glucose

Diabetes September 2004, Vol.53, 2366-2374. doi:https://doi.org/10.2337/diabetes.53.9.2366

Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

Mary C. Gannon; Frank Q. Nuttall

Abstract

View articletitled, Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes

Open the PDF for in another window

Topics: diabetes mellitus, type 2 , diet , glucose , carbohydrates , glycemic control

Diabetes September 2004, Vol.53, 2375-2382. doi:https://doi.org/10.2337/diabetes.53.9.2375

Expression of Angiogenic Factors During Acute Coronary Syndromes in Human Type 2 Diabetes

Raffaele Marfella; Katherine Esposito; Francesco Nappo; Mario Siniscalchi; Ferdinando Carlo Sasso; Michele Portoghese; Maria Pia Di Marino; Alfonso Baldi; Salvatore Cuzzocrea; Clara Di Filippo; Guglielmo Barboso; Feliciano Baldi; Francesco Rossi; Michele D’Amico; Dario Giugliano

Abstract

View articletitled, Expression of Angiogenic Factors During Acute Coronary Syndromes in Human Type 2 Diabetes

Open the PDF for in another window

Topics: 3-nitrotyrosine , angiogenesis factor , biopsy , heart ventricle , ischemia

Diabetes September 2004, Vol.53, 2383-2391. doi:https://doi.org/10.2337/diabetes.53.9.2383

Increased Expression of G_i-Coupled Muscarinic Acetylcholine Receptor and G_i in Atrium of Elderly Diabetic Subjects

Mark D. Richardson; Jason D. Kilts; Madan M. Kwatra

Abstract

View articletitled, Increased Expression of Gi-Coupled Muscarinic Acetylcholine Receptor and Gi in Atrium of Elderly Diabetic Subjects

Open the PDF for in another window

Topics: atrium , older adult , muscarinic acetylcholine receptor

Diabetes September 2004, Vol.53, 2392-2396. doi:https://doi.org/10.2337/diabetes.53.9.2392

Effect of Intravenous Infusion of Exenatide (Synthetic Exendin-4) on Glucose-Dependent Insulin Secretion and Counterregulation During Hypoglycemia

Kristine B. Degn; Birgitte Brock; Claus B. Juhl; Christian B. Djurhuus; Jaime Grubert; Dennis Kim; Jenny Han; Kristin Taylor; Mark Fineman; Ole Schmitz

Abstracts

View articletitled, Effect of Intravenous Infusion of Exenatide (Synthetic Exendin-4) on Glucose-Dependent Insulin Secretion and Counterregulation During Hypoglycemia

Open the PDF for in another window

Topics: exenatide , glucose , hypoglycemia , glucagon , arm

Diabetes September 2004, Vol.53, 2397-2403. doi:https://doi.org/10.2337/diabetes.53.9.2397

Complications

Studies of Rat and Human Retinas Predict a Role for the Polyol Pathway in Human Diabetic Retinopathy

Zeina Dagher; Yong Seek Park; Veronica Asnaghi; Todd Hoehn; Chiara Gerhardinger; Mara Lorenzi

Abstracts

View articletitled, Studies of Rat and Human Retinas Predict a Role for the Polyol Pathway in Human Diabetic Retinopathy

Open the PDF for in another window

Topics: aldehyde reductase , blood capillaries , diabetic retinopathy , endothelial cells , glucose

Diabetes September 2004, Vol.53, 2404-2411. doi:https://doi.org/10.2337/diabetes.53.9.2404

Involvement of Brain-Derived Neurotrophic Factor in Early Retinal Neuropathy of Streptozotocin-Induced Diabetes in Rats: Therapeutic Potential of Brain-Derived Neurotrophic Factor for Dopaminergic Amacrine Cells

Masaaki Seki; Takayuki Tanaka; Hiroyuki Nawa; Tomoaki Usui; Takeo Fukuchi; Kazuhito Ikeda; Haruki Abe; Nobuyuki Takei

Abstract

View articletitled, Involvement of Brain-Derived Neurotrophic Factor in Early Retinal Neuropathy of Streptozotocin-Induced Diabetes in Rats: Therapeutic Potential of Brain-Derived Neurotrophic Factor for Dopaminergic Amacrine Cells

Open the PDF for in another window

Topics: amacrine cells , brain-derived neurotrophic factor , dopamine , retina , streptozocin

Diabetes September 2004, Vol.53, 2412-2419. doi:https://doi.org/10.2337/diabetes.53.9.2412

Development of Albuminuria and Glomerular Lesions in Normoglycemic B6 Recipients of db/db Mice Bone Marrow: The Role of Mesangial Cell Progenitors

Feng Zheng; Flavia Cornacchia; Ivonne Schulman; Anita Banerjee; Qing-li Cheng; Mylene Potier; Anna Rita Plati; Mariana Berho; Sharon J. Elliot; Jie Li; Alessia Fornoni; Yun-Juan Zang; Ariel Zisman; Liliane J. Striker; Gary E. Striker

Abstract

View articletitled, Development of Albuminuria and Glomerular Lesions in Normoglycemic B6 Recipients of db/db Mice Bone Marrow: The Role of Mesangial Cell Progenitors

Open the PDF for in another window

Topics: gelatinase a , insulin , kidney glomerulus , mesangial cells , mice

Diabetes September 2004, Vol.53, 2420-2427. doi:https://doi.org/10.2337/diabetes.53.9.2420

Changes in IGF Activities in Human Diabetic Vitreous

Clyde Guidry; Richard Feist; Robert Morris; Charles W. Hardwick

Abstract

View articletitled, Changes in IGF Activities in Human Diabetic Vitreous

Open the PDF for in another window

Topics: growth factor , vitreous body , platelet-derived growth factor , insulin-like growth factor i

Diabetes September 2004, Vol.53, 2428-2435. doi:https://doi.org/10.2337/diabetes.53.9.2428

Nitration and Functional Loss of Voltage-Gated K⁺ Channels in Rat Coronary Microvessels Exposed to High Glucose

Hongwei Li; David D. Gutterman; Nancy J. Rusch; Aaron Bubolz; Yanping Liu

Abstract

View articletitled, Nitration and Functional Loss of Voltage-Gated K+ Channels in Rat Coronary Microvessels Exposed to High Glucose

Open the PDF for in another window

Topics: 3-nitrotyrosine , dilators , glucose , microvessels , urate level

Diabetes September 2004, Vol.53, 2436-2442. doi:https://doi.org/10.2337/diabetes.53.9.2436

Leptin Stimulates Ischemia-Induced Retinal Neovascularization: Possible Role of Vascular Endothelial Growth Factor Expressed in Retinal Endothelial Cells

Eri Suganami; Hitoshi Takagi; Hirokazu Ohashi; Kiyoshi Suzuma; Izumi Suzuma; Hideyasu Oh; Daisuke Watanabe; Tomonari Ojima; Takayoshi Suganami; Yasushi Fujio; Kazuwa Nakao; Yoshihiro Ogawa; Nagahisa Yoshimura

Abstract

View articletitled, Leptin Stimulates Ischemia-Induced Retinal Neovascularization: Possible Role of Vascular Endothelial Growth Factor Expressed in Retinal Endothelial Cells

Open the PDF for in another window

Topics: endothelial cells , leptin , retinal neovascularization , vascular endothelial growth factor a , ischemia

Diabetes September 2004, Vol.53, 2443-2448. doi:https://doi.org/10.2337/diabetes.53.9.2443

Population-Based Assessment of Familial Clustering of Diabetic Nephropathy in Type 1 Diabetes

Valma Harjutsalo; Shuichi Katoh; Cinzia Sarti; Naoko Tajima; Jaakko Tuomilehto

Abstract

View articletitled, Population-Based Assessment of Familial Clustering of Diabetic Nephropathy in Type 1 Diabetes

Open the PDF for in another window

Topics: diabetes mellitus, type 1 , diabetic nephropathy , kidney diseases , kidney failure, chronic , proband

Diabetes September 2004, Vol.53, 2449-2454. doi:https://doi.org/10.2337/diabetes.53.9.2449

Functional Variants in the Glutathione Peroxidase-1 (GPx-1) Gene Are Associated With Increased Intima-Media Thickness of Carotid Arteries and Risk of Macrovascular Diseases in Japanese Type 2 Diabetic Patients

Tohru Hamanishi; Hiroto Furuta; Hisako Kato; Asako Doi; Masanori Tamai; Hiroko Shimomura; Setsuya Sakagashira; Masahiro Nishi; Hideyuki Sasaki; Tokio Sanke; Kishio Nanjo

Abstract

View articletitled, Functional Variants in the Glutathione Peroxidase-1 (GPx-1) Gene Are Associated With Increased Intima-Media Thickness of Carotid Arteries and Risk of Macrovascular Diseases in Japanese Type 2 Diabetic Patients

Open the PDF for in another window

Topics: genes , glutathione , intima media thickness , polymorphism , peroxidase

Diabetes September 2004, Vol.53, 2455-2460. doi:https://doi.org/10.2337/diabetes.53.9.2455

Studies of the Peptide YY and Neuropeptide Y2 Receptor Genes in Relation to Human Obesity and Obesity-Related Traits

Chiao-Chien Connie Hung; Fraser Pirie; Jian’an Luan; Emma Lank; Ayesha Motala; Giles S.H. Yeo; Julia M. Keogh; Nicholas J. Wareham; Stephen O’Rahilly; I. Sadaf Farooqi

Abstracts

View articletitled, Studies of the Peptide YY and Neuropeptide Y2 Receptor Genes in Relation to Human Obesity and Obesity-Related Traits

Supplementary data

Open the PDF for in another window

Topics: genes , obesity , peptide yy , polymerase chain reaction , neuropeptides

Diabetes September 2004, Vol.53, 2461-2466. doi:https://doi.org/10.2337/diabetes.53.9.2461

Genetic Variation in BEACON Influences Quantitative Variation in Metabolic Syndrome–Related Phenotypes

Jeremy B. Jowett; Kate S. Elliott; Joanne E. Curran; Nicola Hunt; Ken R. Walder; Greg R. Collier; Paul Z. Zimmet; John Blangero

Abstracts

View articletitled, Genetic Variation in BEACON Influences Quantitative Variation in Metabolic Syndrome–Related Phenotypes

Open the PDF for in another window

Topics: genetics , indomethacin , metabolic syndrome x , obesity , phenotype

Diabetes September 2004, Vol.53, 2467-2472. doi:https://doi.org/10.2337/diabetes.53.9.2467

Adiponectin and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

Bruce B. Duncan; Maria Inês Schmidt; James S. Pankow; Heejung Bang; David Couper; Christie M. Ballantyne; Ron C. Hoogeveen; Gerardo Heiss

Abstract

View articletitled, Adiponectin and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study

Open the PDF for in another window

Topics: adiponectin , aric trial , inflammation , diabetes mellitus, type 2 , insulin

Diabetes September 2004, Vol.53, 2473-2478. doi:https://doi.org/10.2337/diabetes.53.9.2473

Brief Genetics Report

Association Analysis of the Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Gene in Type 1 Diabetes

John S. Hulme; Bryan J. Barratt; Rebecca C.J. Twells; Jason D. Cooper; Chris E. Lowe; Joanna M.M. Howson; Alex C. Lam; Luc J. Smink; David A. Savage; Dag E. Undlien; Cristian Guja; Constantin Ionescu-Tîırgovişte; Eva Tuomilehto-Wolf; Jaakko Tuomilehto; John A. Todd

Abstracts

View articletitled, Association Analysis of the Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Gene in Type 1 Diabetes

Supplementary data

Open the PDF for in another window

Topics: diabetes mellitus, type 1 , genes , lymphocyte specific protein tyrosine kinase p56(lck) , single nucleotide polymorphism , introns

Diabetes September 2004, Vol.53, 2479-2482. doi:https://doi.org/10.2337/diabetes.53.9.2479

Polymorphisms in the Amino Acid Transporter Solute Carrier Family 6 (Neurotransmitter Transporter) Member 14 Gene Contribute to Polygenic Obesity in French Caucasians

Emmanuelle Durand; Philippe Boutin; David Meyre; M. Aline Charles; Karine Clement; Christian Dina; Philippe Froguel

Abstracts

View articletitled, Polymorphisms in the Amino Acid Transporter Solute Carrier Family 6 (Neurotransmitter Transporter) Member 14 Gene Contribute to Polygenic Obesity in French Caucasians

Open the PDF for in another window

Topics: amino acid transporter , genes , membrane transport proteins , neurotransmitters , obesity

Diabetes September 2004, Vol.53, 2483-2486. doi:https://doi.org/10.2337/diabetes.53.9.2483

A Quantitative Trait Locus Influencing Fasting Plasma Glucose in Chromosome Region 18q22-23

Wei-Dong Li; Chuanhui Dong; Ding Li; Cathleen Garrigan; R. Arlen Price

Abstract

View articletitled, A Quantitative Trait Locus Influencing Fasting Plasma Glucose in Chromosome Region 18q22-23

Open the PDF for in another window

Topics: fasting , fasting blood glucose measurement , genotype determination , plasma glucose , chromosomes

Diabetes September 2004, Vol.53, 2487-2491. doi:https://doi.org/10.2337/diabetes.53.9.2487

Pharmacology and Therapeutic

A Recombinant Human Glucagon-Like Peptide (GLP)-1–Albumin Protein (Albugon) Mimics Peptidergic Activation of GLP-1 Receptor–Dependent Pathways Coupled With Satiety, Gastrointestinal Motility, and Glucose Homeostasis

Laurie L. Baggio; Qingling Huang; Theodore J. Brown; Daniel J. Drucker

Abstract

View articletitled, A Recombinant Human Glucagon-Like Peptide (GLP)-1–Albumin Protein (Albugon) Mimics Peptidergic Activation of GLP-1 Receptor–Dependent Pathways Coupled With Satiety, Gastrointestinal Motility, and Glucose Homeostasis

Open the PDF for in another window

Topics: agonists , albumins , glucagon , glucagon-like peptide 1 , glucagon-like peptide-1 receptor

Diabetes September 2004, Vol.53, 2492-2500. doi:https://doi.org/10.2337/diabetes.53.9.2492

Regeneration of the Heart in Diabetes by Selective Copper Chelation

Abstracts

View articletitled, Regeneration of the Heart in Diabetes by Selective Copper Chelation

Open the PDF for in another window

Topics: rats , trientine , urinary tract , heart

Diabetes September 2004, Vol.53, 2501-2508. doi:https://doi.org/10.2337/diabetes.53.9.2501

Recombinant Human Erythropoietin Stimulates Angiogenesis and Wound Healing in the Genetically Diabetic Mouse

Mariarosaria Galeano; Domenica Altavilla; Domenico Cucinotta; Giuseppina T. Russo; Margherita Calò; Alessandra Bitto; Herbert Marini; Rolando Marini; Elena B. Adamo; Paolo Seminara; Letteria Minutoli; Valerio Torre; Francesco Squadrito

Abstract

View articletitled, Recombinant Human Erythropoietin Stimulates Angiogenesis and Wound Healing in the Genetically Diabetic Mouse

Open the PDF for in another window

Topics: angiogenesis , cd31 antigens , mice , vascular endothelial growth factor a , wound healing

Diabetes September 2004, Vol.53, 2509-2517. doi:https://doi.org/10.2337/diabetes.53.9.2509

Erratum

Extract

View articletitled, Erratum

Open the PDF for in another window

Topics: insulin resistance , obesity , resistin

Diabetes September 2004, Vol.53, 2518. doi:https://doi.org/10.2337/diabetes.53.9.2518

Issues

Perspective in Diabetes

New Methodology and Database

Metabolism

Signal Transduction

Obesity Study

Immunology and Transplantation

Islet Study

Pathophysiology

Complications

Brief Genetics Report

Pharmacology and Therapeutic

Erratum

Email alerts

RSS Feeds

Journals

Books

Clinical Compendia

News

Other

About

Resources

This Feature Is Available To Subscribers Only