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Issues
1 January 2005
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Postprandial Hyperglycemia and Diabetes Complications: Is It Time to Treat?
Diabetes January 2005, Vol.54, 1-7. doi:https://doi.org/10.2337/diabetes.54.1.1
Metabolism
Deficiency of Subsarcolemmal Mitochondria in Obesity and Type 2 Diabetes
Vladimir B. Ritov; Elizabeth V. Menshikova; Jing He; Robert E. Ferrell; Bret H. Goodpaster; David E. Kelley
Diabetes January 2005, Vol.54, 8-14. doi:https://doi.org/10.2337/diabetes.54.1.8
Signal Transduction
Differential Effects of Glucose and Lactate on Glucosensing Neurons in the Ventromedial Hypothalamic Nucleus
Diabetes January 2005, Vol.54, 15-22. doi:https://doi.org/10.2337/diabetes.54.1.15
HIV-1 Accessory Protein Vpr Inhibits the Effect of Insulin on the Foxo Subfamily of Forkhead Transcription Factors by Interfering With Their Binding to 14-3-3 Proteins: Potential Clinical Implications Regarding the Insulin Resistance of HIV-1–Infected Patients
Tomoshige Kino; Massimo U. De Martino; Evangelia Charmandari; Takamasa Ichijo; Taoufik Outas; George P. Chrousos
Diabetes January 2005, Vol.54, 23-31. doi:https://doi.org/10.2337/diabetes.54.1.23
Increased Glucocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Type 1 Expression in Hepatocytes May Contribute to the Phenotype of Type 2 Diabetes in db/db Mice
Yanjun Liu; Yuichi Nakagawa; Ying Wang; Reiko Sakurai; Pinky V. Tripathi; Kabirullah Lutfy; Theodore C. Friedman
Diabetes January 2005, Vol.54, 32-40. doi:https://doi.org/10.2337/diabetes.54.1.32
Increased Phosphorylation of Akt Substrate of 160 kDa (AS160) in Rat Skeletal Muscle in Response to Insulin or Contractile Activity
Diabetes January 2005, Vol.54, 41-50. doi:https://doi.org/10.2337/diabetes.54.1.41
Obesity Studies
Growth Hormone Overexpression in the Central Nervous System Results in Hyperphagia-Induced Obesity Associated With Insulin Resistance and Dyslipidemia
Mohammad Bohlooly-Y; Bob Olsson; Carl E.G. Bruder; Daniel Lindén; Klara Sjögren; Mikael Bjursell; Emil Egecioglu; Lennart Svensson; Peter Brodin; John C. Waterton; Olle G.P. Isaksson; Frank Sundler; Bo Ahrén; Claes Ohlsson; Jan Oscarsson; Jan Törnell
Diabetes January 2005, Vol.54, 51-62. doi:https://doi.org/10.2337/diabetes.54.1.51
Enhanced Hypothalamic AMP-Activated Protein Kinase Activity Contributes to Hyperphagia in Diabetic Rats
Churl Namkoong; Min Seon Kim; Pil Geum Jang; Sung Min Han; Hye Sun Park; Eun Hee Koh; Woo Je Lee; Jong Yeon Kim; In Sun Park; Joong Yeol Park; Ki Up Lee
Diabetes January 2005, Vol.54, 63-68. doi:https://doi.org/10.2337/diabetes.54.1.63
Immunology and Transplantation
Islet-infiltrating B-Cells in Nonobese Diabetic Mice Predominantly Target Nervous System Elements
Jorge Carrillo; Maria Carmen Puertas; Aurora Alba; Rosa Maria Ampudia; Xavier Pastor; Raquel Planas; Nadal Riutort; Nuria Alonso; Ricardo Pujol-Borrell; Pere Santamaria; Marta Vives-Pi; Joan Verdaguer
Diabetes January 2005, Vol.54, 69-77. doi:https://doi.org/10.2337/diabetes.54.1.69
Treatment With Granulocyte Colony−Stimulating Factor Prevents Diabetes in NOD Mice by Recruiting Plasmacytoid Dendritic Cells and Functional CD4+CD25+ Regulatory T-Cells
Hassen Kared; Annie Masson; Homa Adle-Biassette; Jean-François Bach; Lucienne Chatenoud; Flora Zavala
Diabetes January 2005, Vol.54, 78-84. doi:https://doi.org/10.2337/diabetes.54.1.78
Hyperglycemia Induces Monocytic Release of Interleukin-6 via Induction of Protein Kinase C-α and -β
Diabetes January 2005, Vol.54, 85-91. doi:https://doi.org/10.2337/diabetes.54.1.85
Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes
Diabetes January 2005, Vol.54, 92-99. doi:https://doi.org/10.2337/diabetes.54.1.92
β-Cell Function Following Human Islet Transplantation for Type 1 Diabetes
Diabetes January 2005, Vol.54, 100-106. doi:https://doi.org/10.2337/diabetes.54.1.100
Autoimmune Diabetes and Resistance to Xenograft Transplantation Tolerance in NOD Mice
Ethel J. Gordon; Linda S. Wicker; Laurence B. Peterson; David V. Serreze; Thomas G. Markees; Leonard D. Shultz; Aldo A. Rossini; Dale L. Greiner; John P. Mordes
Diabetes January 2005, Vol.54, 107-115. doi:https://doi.org/10.2337/diabetes.54.1.107
Islet Studies
Uncoupling of Nutrient Metabolism From Insulin Secretion by Overexpression of Cytosolic Phospholipase A2
Helen M. Milne; Chris J. Burns; Paul E. Squires; Nicholas D. Evans; John Pickup; Peter M. Jones; Shanta J. Persaud
Diabetes January 2005, Vol.54, 116-124. doi:https://doi.org/10.2337/diabetes.54.1.116
Nuclear Factor-κB Activity in β-Cells Is Required for Glucose-Stimulated Insulin Secretion
Diabetes January 2005, Vol.54, 125-132. doi:https://doi.org/10.2337/diabetes.54.1.125
Genetic Background Determines the Size and Structure of the Endocrine Pancreas
Diabetes January 2005, Vol.54, 133-137. doi:https://doi.org/10.2337/diabetes.54.1.133
Dynamic Changes in β-Cell Mass and Pancreatic Insulin During the Evolution of Nutrition-Dependent Diabetes in Psammomys obesus: Impact of Glycemic Control
Nurit Kaiser; Michal Yuli; Gökhan Üçkaya; Andrei I. Oprescu; Marie-France Berthault; Catherine Kargar; Marc Y. Donath; Erol Cerasi; Alain Ktorza
Diabetes January 2005, Vol.54, 138-145. doi:https://doi.org/10.2337/diabetes.54.1.138
Pathophysiology
Glucagon-like Peptide 1 Can Directly Protect the Heart Against Ischemia/Reperfusion Injury
Diabetes January 2005, Vol.54, 146-151. doi:https://doi.org/10.2337/diabetes.54.1.146
Delayed Transcapillary Delivery of Insulin to Muscle Interstitial Fluid After Oral Glucose Load in Obese Subjects
Diabetes January 2005, Vol.54, 152-157. doi:https://doi.org/10.2337/diabetes.54.1.152
Physical Activity in the Prevention of Type 2 Diabetes: The Finnish Diabetes Prevention Study
David E. Laaksonen; Jaana Lindström; Timo A. Lakka; Johan G. Eriksson; Leo Niskanen; Katja Wikström; Sirkka Aunola; Sirkka Keinänen-Kiukaanniemi; Mauri Laakso; Timo T. Valle; Pirjo Ilanne-Parikka; Anne Louheranta; Helena Hämäläinen; Merja Rastas; Virpi Salminen; Zygimantas Cepaitis; Martti Hakumäki; Hannu Kaikkonen; Pirjo Härkönen; Jouko Sundvall; Jaakko Tuomilehto; Matti Uusitupa; for the Finnish Diabetes Prevention Study Group
Diabetes January 2005, Vol.54, 158-165. doi:https://doi.org/10.2337/diabetes.54.1.158
Predictors of and Longitudinal Changes in Insulin Sensitivity and Secretion Preceding Onset of Type 2 Diabetes
Valeriya Lyssenko; Peter Almgren; Dragi Anevski; Roland Perfekt; Kaj Lahti; Michael Nissén; Bo Isomaa; Björn Forsen; Nils Homström; Carola Saloranta; Marja-Riitta Taskinen; Leif Groop; Tiinamaija Tuomi; for the Botnia Study Group
Diabetes January 2005, Vol.54, 166-174. doi:https://doi.org/10.2337/diabetes.54.1.166
Impairment of Host Resistance to Listeria monocytogenes Infection in Liver of db/db and ob/ob Mice
Shin Ikejima; Sanae Sasaki; Hiroshi Sashinami; Fumiaki Mori; Yoshiji Ogawa; Teruo Nakamura; Yoshinao Abe; Koichi Wakabayashi; Toshihiro Suda; Akio Nakane
Diabetes January 2005, Vol.54, 182-189. doi:https://doi.org/10.2337/diabetes.54.1.182
Evidence for Accelerated Rates of Glutathione Utilization and Glutathione Depletion in Adolescents With Poorly Controlled Type 1 Diabetes
Diabetes January 2005, Vol.54, 190-196. doi:https://doi.org/10.2337/diabetes.54.1.190
Postnatal Diet-Induced Obesity in Rats Upregulates Systemic and Adipose Tissue Glucocorticoid Metabolism During Development and in Adulthood: Its Relationship With the Metabolic Syndrome
Sandrine Boullu-Ciocca; Anne Dutour; Viviane Guillaume; Vincent Achard; Charles Oliver; Michel Grino
Diabetes January 2005, Vol.54, 197-203. doi:https://doi.org/10.2337/diabetes.54.1.197
Complications
The Effect of Vitamin E on Endothelial Function of Micro- and Macrocirculation and Left Ventricular Function in Type 1 and Type 2 Diabetic Patients
Panayiotis A. Economides; Lalita Khaodhiar; Antonella Caselli; A. Enrique Caballero; Hillary Keenan; Sven-Erik Bursell; George L. King; Michael T. Johnstone; Edward S. Horton; Aristidis Veves
Diabetes January 2005, Vol.54, 204-211. doi:https://doi.org/10.2337/diabetes.54.1.204
Nitrergic Neurodegeneration in Cerebral Arteries of Streptozotocin-Induced Diabetic Rats: A New Insight into Diabetic Stroke
Diabetes January 2005, Vol.54, 212-219. doi:https://doi.org/10.2337/diabetes.54.1.212
a-Series Gangliosides Mediate the Effects of Advanced Glycation End Products on Pericyte and Mesangial Cell Proliferation: A Common Mediator for Retinal and Renal Microangiopathy?
Elodie Masson; Lysiane Troncy; Daniel Ruggiero; Nicolas Wiernsperger; Michel Lagarde; Samer El Bawab
Diabetes January 2005, Vol.54, 220-227. doi:https://doi.org/10.2337/diabetes.54.1.220
Altered Transcapillary Escape of Albumin and Microalbuminuria Reflects Two Different Pathogenetic Mechanisms
Romano Nosadini; Mario Velussi; Enrico Brocco; Cataldo Abaterusso; Francesco Piarulli; Giuseppe Morgia; Andrea Satta; Rossana Faedda; Avinash Abhyankar; Holger Luthman; Giancarlo Tonolo
Diabetes January 2005, Vol.54, 228-233. doi:https://doi.org/10.2337/diabetes.54.1.228
Aldose Reductase Inhibition Counteracts Oxidative-Nitrosative Stress and Poly(ADP-Ribose) Polymerase Activation in Tissue Sites for Diabetes Complications
Irina G. Obrosova; Pal Pacher; Csaba Szabó; Zsuzsanna Zsengeller; Hiroko Hirooka; Martin J. Stevens; Mark A. Yorek
Diabetes January 2005, Vol.54, 234-242. doi:https://doi.org/10.2337/diabetes.54.1.234
Decreased Expression of Pigment Epithelium-Derived Factor Is Involved in the Pathogenesis of Diabetic Nephropathy
Diabetes January 2005, Vol.54, 243-250. doi:https://doi.org/10.2337/diabetes.54.1.243
Pharmacology and Therapeutics
Development of a Long-Acting Insulin Analog Using Albumin Fusion Technology
Alokesh Duttaroy; Palanisamy Kanakaraj; Blaire L. Osborn; Helmut Schneider; Oxana K. Pickeral; Cecil Chen; Guiyi Zhang; Shashi Kaithamana; Mallika Singh; Robert Schulingkamp; Dan Crossan; Jason Bock; Thomas E. Kaufman; Peter Reavey; Melisa Carey-Barber; Surekha R. Krishnan; Andy Garcia; Kelly Murphy; Jana K. Siskind; Malia A. McLean; Susan Cheng; Steve Ruben; Charles E. Birse; Olivier Blondel
Diabetes January 2005, Vol.54, 251-258. doi:https://doi.org/10.2337/diabetes.54.1.251
Genetics
Genetic Linkage and Association of the Growth Hormone Secretagogue Receptor (Ghrelin Receptor) Gene in Human Obesity
Andrea Baessler; Michael J. Hasinoff; Marcus Fischer; Wibke Reinhard; Gabriele E. Sonnenberg; Michael Olivier; Jeanette Erdmann; Heribert Schunkert; Angela Doering; Howard J. Jacob; Anthony G. Comuzzie; Ahmed H. Kissebah; Anne E. Kwitek
Diabetes January 2005, Vol.54, 259-267. doi:https://doi.org/10.2337/diabetes.54.1.259
Linkage of Plasma Adiponectin Levels to 3q27 Explained by Association With Variation in the APM1 Gene
Toni I. Pollin; Keith Tanner; Jeffrey R. O’Connell; Sandra H. Ott; Coleen M. Damcott; Alan R. Shuldiner; John C. McLenithan; Braxton D. Mitchell
Diabetes January 2005, Vol.54, 268-274. doi:https://doi.org/10.2337/diabetes.54.1.268
Brief Genetics Reports
Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians
Barbora Vozarova de Courten; Robert L. Hanson; Tohru Funahashi; Robert S. Lindsay; Yuji Matsuzawa; Sachiyo Tanaka; Farook Thameem; Jonathan D. Gruber; Philippe Froguel; Johanna K. Wolford
Diabetes January 2005, Vol.54, 284-289. doi:https://doi.org/10.2337/diabetes.54.1.284
A Genome Scan for Fasting Insulin and Fasting Glucose Identifies a Quantitative Trait Locus on Chromosome 17p: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
Stephen S. Rich; Donald W. Bowden; Steven M. Haffner; Jill M. Norris; Mohammed F. Saad; Braxton D. Mitchell; Jerome I. Rotter; Carl D. Langefeld; Catherine C. Hedrick; Lynne E. Wagenknecht; Richard N. Bergman
Diabetes January 2005, Vol.54, 290-295. doi:https://doi.org/10.2337/diabetes.54.1.290
