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Issues
1 October 2005
ISSN 0012-1797
EISSN 1939-327X
Metabolism
Interaction of Glucokinase With the Liver Regulatory Protein Is Conferred by Leucine-Asparagine Motifs of the Enzyme
Diabetes October 2005, Vol.54, 2829-2837. doi:https://doi.org/10.2337/diabetes.54.10.2829
Obesity Studies
Activation of the Peripheral Endocannabinoid System in Human Obesity
Stefan Engeli; Jana Böhnke; Mareike Feldpausch; Kerstin Gorzelniak; Jürgen Janke; Sándor Bátkai; Pál Pacher; Judy Harvey-White; Friedrich C. Luft; Arya M. Sharma; Jens Jordan
Diabetes October 2005, Vol.54, 2838-2843. doi:https://doi.org/10.2337/diabetes.54.10.2838
Plasma Visfatin Concentrations and Fat Depot–Specific mRNA Expression in Humans
Janin Berndt; Nora Klöting; Susan Kralisch; Peter Kovacs; Mathias Fasshauer; Michael R. Schön; Michael Stumvoll; Matthias Blüher
Diabetes October 2005, Vol.54, 2911-2916. doi:https://doi.org/10.2337/diabetes.54.10.2911
Islet Studies
Attenuated Wnt Signaling Perturbs Pancreatic Growth but Not Pancreatic Function
Diabetes October 2005, Vol.54, 2844-2851. doi:https://doi.org/10.2337/diabetes.54.10.2844
Membrane Phosphoinositides Control Insulin Secretion Through Their Effects on ATP-Sensitive K+ Channel Activity
Diabetes October 2005, Vol.54, 2852-2858. doi:https://doi.org/10.2337/diabetes.54.10.2852
BETA2/NeuroD Protein Can Be Transduced Into Cells Due to an Arginine- and Lysine-Rich Sequence
Diabetes October 2005, Vol.54, 2859-2866. doi:https://doi.org/10.2337/diabetes.54.10.2859
Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing β-Cell–Like Cells
Diabetes October 2005, Vol.54, 2867-2874. doi:https://doi.org/10.2337/diabetes.54.10.2867
Increased Fatty Acid Desaturation and Enhanced Expression of Stearoyl Coenzyme A Desaturase Protects Pancreatic β-Cells from Lipoapoptosis
Anna K. Busch; Ebru Gurisik; Damien V. Cordery; Michelle Sudlow; Gareth S. Denyer; D. Ross Laybutt; William E. Hughes; Trevor J. Biden
Diabetes October 2005, Vol.54, 2917-2924. doi:https://doi.org/10.2337/diabetes.54.10.2917
ATP-Sensitive K+ Channel Signaling in Glucokinase-Deficient Diabetes
Diabetes October 2005, Vol.54, 2925-2931. doi:https://doi.org/10.2337/diabetes.54.10.2925
Pathophysiology
Bone Formation Is Impaired in a Model of Type 1 Diabetes
Kathryn M. Thrailkill; Lichu Liu; Elizabeth C. Wahl; Robert C. Bunn; Daniel S. Perrien; Gael E. Cockrell; Robert A. Skinner; William R. Hogue; Adam A. Carver; John L. Fowlkes; James Aronson; Charles K. Lumpkin, Jr.
Diabetes October 2005, Vol.54, 2875-2881. doi:https://doi.org/10.2337/diabetes.54.10.2875
Elevated Levels of Interleukin-18 Predict the Development of Type 2 Diabetes: Results From the MONICA/KORA Augsburg Study, 1984–2002
Barbara Thorand; Hubert Kolb; Jens Baumert; Wolfgang Koenig; Lloyd Chambless; Christa Meisinger; Thomas Illig; Stephan Martin; Christian Herder
Diabetes October 2005, Vol.54, 2932-2938. doi:https://doi.org/10.2337/diabetes.54.10.2932
Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation
Peter Plomgaard; Karim Bouzakri; Rikke Krogh-Madsen; Bettina Mittendorfer; Juleen R. Zierath; Bente K. Pedersen
Diabetes October 2005, Vol.54, 2939-2945. doi:https://doi.org/10.2337/diabetes.54.10.2939
Serum Glucagon Counterregulatory Hormonal Response to Hypoglycemia Is Blunted in Congenital Hyperinsulinism
Diabetes October 2005, Vol.54, 2946-2951. doi:https://doi.org/10.2337/diabetes.54.10.2946
Complications
Gene Delivery of Tim44 Reduces Mitochondrial Superoxide Production and Ameliorates Neointimal Proliferation of Injured Carotid Artery in Diabetic Rats
Takashi Matsuoka; Jun Wada; Izumi Hashimoto; Yanling Zhang; Jun Eguchi; Norio Ogawa; Kenichi Shikata; Yashpal S. Kanwar; Hirofumi Makino
Diabetes October 2005, Vol.54, 2882-2890. doi:https://doi.org/10.2337/diabetes.54.10.2882
Antiangiogenic Endostatin Peptide Ameliorates Renal Alterations in the Early Stage of a Type 1 Diabetic Nephropathy Model
Kunihiro Ichinose; Yohei Maeshima; Yoshihiko Yamamoto; Hiroyuki Kitayama; Yuki Takazawa; Kumiko Hirokoshi; Hitoshi Sugiyama; Yasushi Yamasaki; Katsumi Eguchi; Hirofumi Makino
Diabetes October 2005, Vol.54, 2891-2903. doi:https://doi.org/10.2337/diabetes.54.10.2891
The Pathogenesis of Staphylococcus aureus Infection in the Diabetic NOD Mouse
Diabetes October 2005, Vol.54, 2904-2910. doi:https://doi.org/10.2337/diabetes.54.10.2904
Mechanism of Perturbation of Integrin-Mediated Cell-Matrix Interactions by Reactive Carbonyl Compounds and Its Implication for Pathogenesis of Diabetic Nephropathy
Vadim K. Pedchenko; Sergei V. Chetyrkin; Peale Chuang; Amy-Joan L. Ham; Moin A. Saleem; Peter W. Mathieson; Billy G. Hudson; Paul A. Voziyan
Diabetes October 2005, Vol.54, 2952-2960. doi:https://doi.org/10.2337/diabetes.54.10.2952
Modulation of the Renal Response to ACE Inhibition by ACE Insertion/Deletion Polymorphism During Hyperglycemia in Normotensive, Normoalbuminuric Type 1 Diabetic Patients
Laurent Weekers; Béatrice Bouhanick; Samy Hadjadj; Yves Gallois; Ronen Roussel; Franck Pean; Amos Ankotche; Gilles Chatellier; François Alhenc-Gelas; Pierre J. Lefebvre; Michel Marre
Diabetes October 2005, Vol.54, 2961-2967. doi:https://doi.org/10.2337/diabetes.54.10.2961
Effects of Insulin on Methionine and Homocysteine Kinetics in Type 2 Diabetes With Nephropathy
Paolo Tessari; Anna Coracina; Edward Kiwanuka; Monica Vedovato; Monica Vettore; Anna Valerio; Michela Zaramella; Giacomo Garibotto
Diabetes October 2005, Vol.54, 2968-2976. doi:https://doi.org/10.2337/diabetes.54.10.2968
Statins Ameliorate Endothelial Barrier Permeability Changes in the Cerebral Tissue of Streptozotocin-Induced Diabetic Rats
Diabetes October 2005, Vol.54, 2977-2982. doi:https://doi.org/10.2337/diabetes.54.10.2977
Factors Associated With Frequent Remission of Microalbuminuria in Patients With Type 2 Diabetes
Shin-ichi Araki; Masakazu Haneda; Toshiro Sugimoto; Motohide Isono; Keiji Isshiki; Atsunori Kashiwagi; Daisuke Koya
Diabetes October 2005, Vol.54, 2983-2987. doi:https://doi.org/10.2337/diabetes.54.10.2983
Pharmacology & Therapeutics
Dipeptidyl Peptidase IV Inhibition for the Treatment of Type 2 Diabetes: Potential Importance of Selectivity Over Dipeptidyl Peptidases 8 and 9
George R. Lankas; Barbara Leiting; Ranabir Sinha Roy; George J. Eiermann; Maria G. Beconi; Tesfaye Biftu; Chi-Chung Chan; Scott Edmondson; William P. Feeney; Huaibing He; Dawn E. Ippolito; Dooseop Kim; Kathryn A. Lyons; Hyun O. Ok; Reshma A. Patel; Aleksandr N. Petrov; Kelly Ann Pryor; Xiaoxia Qian; Leah Reigle; Andrea Woods; Joseph K. Wu; Dennis Zaller; Xiaoping Zhang; Lan Zhu; Ann E. Weber; Nancy A. Thornberry
Diabetes October 2005, Vol.54, 2988-2994. doi:https://doi.org/10.2337/diabetes.54.10.2988
Genetics
Type 1 Diabetes: Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families
Patrick Concannon; Henry A. Erlich; Cecile Julier; Grant Morahan; Jørn Nerup; Flemming Pociot; John A. Todd; Stephen S. Rich; the Type 1 Diabetes Genetics Consortium
Diabetes October 2005, Vol.54, 2995-3001. doi:https://doi.org/10.2337/diabetes.54.10.2995
Elevated Levels of Mannose-Binding Lectin at Clinical Manifestation of Type 1 Diabetes in Juveniles
Lee H. Bouwman; Peter Eerligh; Onno T. Terpstra; Mohamed R. Daha; Peter de Knijff; Bart E.P.B. Ballieux; G. Jan Bruining; Arno R. van der Slik; Anja Roos; Bart O. Roep
Diabetes October 2005, Vol.54, 3002-3006. doi:https://doi.org/10.2337/diabetes.54.10.3002
Analysis of Quantitative Lipid Traits in the Genetics of NIDDM (GENNID) Study
Diabetes October 2005, Vol.54, 3007-3014. doi:https://doi.org/10.2337/diabetes.54.10.3007
Genetic and Nongenetic Regulation of CAPN10 mRNA Expression in Skeletal Muscle
Emma Carlsson; Pernille Poulsen; Heidi Storgaard; Peter Almgren; Charlotte Ling; Christine Bjørn Jensen; Sten Madsbad; Leif Groop; Allan Vaag; Martin Ridderstråle
Diabetes October 2005, Vol.54, 3015-3020. doi:https://doi.org/10.2337/diabetes.54.10.3015
Brief Genetics Reports
The K121Q Polymorphism of the ENPP1/PC-1 Gene Is Associated With Insulin Resistance/Atherogenic Phenotypes, Including Earlier Onset of Type 2 Diabetes and Myocardial Infarction
Simonetta Bacci; Ornella Ludovico; Sabrina Prudente; Yuan-Yuan Zhang; Rosa Di Paola; Davide Mangiacotti; Anna Rauseo; David Nolan; Jill Duffy; Grazia Fini; Lucia Salvemini; Cesare Amico; Carlo Vigna; Fabio Pellegrini; Claudia Menzaghi; Alessandro Doria; Vincenzo Trischitta
Diabetes October 2005, Vol.54, 3021-3025. doi:https://doi.org/10.2337/diabetes.54.10.3021
A −30G>A Polymorphism of the β-Cell–Specific Glucokinase Promoter Associates With Hyperglycemia in the General Population of Whites
Christian S. Rose; Jakob Ek; Søren A. Urhammer; Charlotte Glümer; Knut Borch-Johnsen; Torben Jørgensen; Oluf Pedersen; Torben Hansen
Diabetes October 2005, Vol.54, 3026-3031. doi:https://doi.org/10.2337/diabetes.54.10.3026
The CIDEA Gene V115F Polymorphism Is Associated With Obesity in Swedish Subjects
Diabetes October 2005, Vol.54, 3032-3034. doi:https://doi.org/10.2337/diabetes.54.10.3032
Variants in Hepatocyte Nuclear Factor 4α Are Modestly Associated With Type 2 Diabetes in Pima Indians
Yunhua Li Muller; Aniello M. Infante; Robert L. Hanson; Latisha Love-Gregory; William Knowler; Clifton Bogardus; Leslie J. Baier
Diabetes October 2005, Vol.54, 3035-3039. doi:https://doi.org/10.2337/diabetes.54.10.3035
Common Polymorphisms in the USF1 Gene Are Not Associated With Type 2 Diabetes in French Caucasians
Diabetes October 2005, Vol.54, 3040-3042. doi:https://doi.org/10.2337/diabetes.54.10.3040
Association Between Peroxisome Proliferator–Activated Receptor γ Haplotypes and the Metabolic Syndrome in French Men and Women
Diabetes October 2005, Vol.54, 3043-3048. doi:https://doi.org/10.2337/diabetes.54.10.3043
Association of Melanin-Concentrating Hormone Receptor 1 5′ Polymorphism With Early-Onset Extreme Obesity
Christopher G. Bell; David Meyre; Chantal Samson; Cliona Boyle; Cécile Lecoeur; Maïte Tauber; Béatrice Jouret; Delphine Jaquet; Claire Levy-Marchal; Marie Aline Charles; Jacques Weill; Fernando Gibson; Charles A. Mein; Philippe Froguel; Andrew J. Walley
Diabetes October 2005, Vol.54, 3049-3055. doi:https://doi.org/10.2337/diabetes.54.10.3049
Perspectives in Diabetes
Apical GLUT2 : A Major Pathway of Intestinal Sugar Absorption
Diabetes October 2005, Vol.54, 3056-3062. doi:https://doi.org/10.2337/diabetes.54.10.3056
