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Issues
1 November 2005
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Diabetes and Insulin Secretion: The ATP-Sensitive K+ Channel (KATP) Connection
Diabetes November 2005, Vol.54, 3065-3072. doi:https://doi.org/10.2337/diabetes.54.11.3065
Islet Studies
Mechanisms of Glucose-Induced Secretion of Pancreatic-Derived Factor (PANDER or FAM3B) in Pancreatic β-Cells
Jichun Yang; Claudia E. Robert; Brant R. Burkhardt; Robert A. Young; Jianmei Wu; Zhiyong Gao; Bryan A. Wolf
Diabetes November 2005, Vol.54, 3217-3228. doi:https://doi.org/10.2337/diabetes.54.11.3217
Restitution of Defective Glucose-Stimulated Insulin Secretion in Diabetic GK Rat by Acetylcholine Uncovers Paradoxical Stimulatory Effect of β-Cell Muscarinic Receptor Activation on cAMP Production
Manuel Dolz; Danielle Bailbé; Marie-Hélène Giroix; Sophie Calderari; Marie-Noelle Gangnerau; Patricia Serradas; Katharina Rickenbach; Jean-Claude Irminger; Bernard Portha
Diabetes November 2005, Vol.54, 3229-3237. doi:https://doi.org/10.2337/diabetes.54.11.3229
Pathophysiology
Effects of Diabetes on Ryanodine Receptor Ca Release Channel (RyR2) and Ca2+ Homeostasis in Rat Heart
Nazmi Yaras; Mehmet Ugur; Semir Ozdemir; Hakan Gurdal; Nuhan Purali; Alain Lacampagne; Guy Vassort; Belma Turan
Diabetes November 2005, Vol.54, 3082-3088. doi:https://doi.org/10.2337/diabetes.54.11.3082
Is There a Role for Locally Produced Interleukin-1 in the Deleterious Effects of High Glucose or the Type 2 Diabetes Milieu to Human Pancreatic Islets?
Nils Welsh; Miriam Cnop; Ilham Kharroubi; Marco Bugliani; Roberto Lupi; Piero Marchetti; Décio L. Eizirik
Diabetes November 2005, Vol.54, 3238-3244. doi:https://doi.org/10.2337/diabetes.54.11.3238
Homocysteine Metabolism in ZDF (Type 2) Diabetic Rats
Enoka P. Wijekoon; Beatrice Hall; Shobhitha Ratnam; Margaret E. Brosnan; Steven H. Zeisel; John T. Brosnan
Diabetes November 2005, Vol.54, 3245-3251. doi:https://doi.org/10.2337/diabetes.54.11.3245
Insulin Resistance, the Metabolic Syndrome, and Incident Cardiovascular Events in the Framingham Offspring Study
Diabetes November 2005, Vol.54, 3252-3257. doi:https://doi.org/10.2337/diabetes.54.11.3252
Celiac-Superior Mesenteric Ganglionectomy, but Not Vagotomy, Suppresses the Sympathoadrenal Response to Insulin-Induced Hypoglycemia
Diabetes November 2005, Vol.54, 3258-3264. doi:https://doi.org/10.2337/diabetes.54.11.3258
Two-Hour Seven-Sample Oral Glucose Tolerance Test and Meal Protocol: Minimal Model Assessment of β-Cell Responsivity and Insulin Sensitivity in Nondiabetic Individuals
Chiara Dalla Man; Marco Campioni; Kenneth S. Polonsky; Rita Basu; Robert A. Rizza; Gianna Toffolo; Claudio Cobelli
Diabetes November 2005, Vol.54, 3265-3273. doi:https://doi.org/10.2337/diabetes.54.11.3265
Withdrawn
Complications
The Human Glomerular Podocyte Is a Novel Target for Insulin Action
Richard J.M. Coward; Gavin I. Welsh; Jing Yang; Candida Tasman; Rachel Lennon; Ania Koziell; Simon Satchell; Geoffrey D. Holman; Dontscho Kerjaschki; Jeremy M. Tavaré; Peter W. Mathieson; Moin A. Saleem
Diabetes November 2005, Vol.54, 3095-3102. doi:https://doi.org/10.2337/diabetes.54.11.3095
Glycation and Carboxymethyllysine Levels in Skin Collagen Predict the Risk of Future 10-Year Progression of Diabetic Retinopathy and Nephropathy in the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications Participants With Type 1 Diabetes
Saul Genuth; Wanjie Sun; Patricia Cleary; David R. Sell; William Dahms; John Malone; William Sivitz; Vincent M. Monnier; for the DCCT Skin Collagen Ancillary Study Group
Diabetes November 2005, Vol.54, 3103-3111. doi:https://doi.org/10.2337/diabetes.54.11.3103
Noninvasive Monitoring of Diabetes-Induced Cutaneous Nerve Fiber Loss and Hypoalgesia in thy1-YFP Transgenic Mice
Diabetes November 2005, Vol.54, 3112-3118. doi:https://doi.org/10.2337/diabetes.54.11.3112
Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of db/db Mice
Alvin K.H. Cheung; Maggie K.L. Fung; Amy C.Y. Lo; Terence T.L. Lam; Kwok Fai So; Stephen S.M. Chung; Sookja K. Chung
Diabetes November 2005, Vol.54, 3119-3125. doi:https://doi.org/10.2337/diabetes.54.11.3119
Susceptibility to Diabetic Nephropathy Is Related to Dicarbonyl and Oxidative Stress
Paul J. Beisswenger; Keith S. Drummond; Robert G. Nelson; Scott K. Howell; Benjamin S. Szwergold; Michael Mauer
Diabetes November 2005, Vol.54, 3274-3281. doi:https://doi.org/10.2337/diabetes.54.11.3274
Reduced Nitric Oxide Concentration in the Renal Cortex of Streptozotocin-Induced Diabetic Rats: Effects on Renal Oxygenation and Microcirculation
Diabetes November 2005, Vol.54, 3282-3287. doi:https://doi.org/10.2337/diabetes.54.11.3282
Genetics
Large Genomic Rearrangements in the Hepatocyte Nuclear Factor-1β (TCF2) Gene Are the Most Frequent Cause of Maturity-Onset Diabetes of the Young Type 5
Christine Bellanné-Chantelot; Séverine Clauin; Dominique Chauveau; Philippe Collin; Michèle Daumont; Claire Douillard; Danièle Dubois-Laforgue; Laurent Dusselier; Jean-François Gautier; Michel Jadoul; Marie Laloi-Michelin; Laetitia Jacquesson; Etienne Larger; Jacques Louis; Marc Nicolino; Jean-François Subra; Jean-Marie Wilhem; Jacques Young; Gilberto Velho; José Timsit
Diabetes November 2005, Vol.54, 3126-3132. doi:https://doi.org/10.2337/diabetes.54.11.3126
Protein Tyrosine Phosphatase-1B Gene PTPN1: Selection of Tagging Single Nucleotide Polymorphisms and Association With Body Fat, Insulin Sensitivity, and the Metabolic Syndrome in a Normal Female Population
Nicola J. Spencer-Jones; Xiaoling Wang; Harold Snieder; Tim D. Spector; Nicholas D. Carter; Sandra D. O’Dell
Diabetes November 2005, Vol.54, 3296-3304. doi:https://doi.org/10.2337/diabetes.54.11.3296
Assessment of 115 Candidate Genes for Diabetic Nephropathy by Transmission/Disequilibrium Test
Diabetes November 2005, Vol.54, 3305-3318. doi:https://doi.org/10.2337/diabetes.54.11.3305
Sequence Variation in PPARG May Underlie Differential Response to Troglitazone
Johanna K. Wolford; Kimberly A. Yeatts; Sharanjeet K. Dhanjal; Mary Helen Black; Anny H. Xiang; Thomas A. Buchanan; Richard M. Watanabe
Diabetes November 2005, Vol.54, 3319-3325. doi:https://doi.org/10.2337/diabetes.54.11.3319
Metabolism
Partial Gene Deletion of Heart-Type Fatty Acid–Binding Protein Limits the Severity of Dietary-Induced Insulin Resistance
Diabetes November 2005, Vol.54, 3133-3139. doi:https://doi.org/10.2337/diabetes.54.11.3133
Liver Markers and Development of the Metabolic Syndrome: The Insulin Resistance Atherosclerosis Study
Anthony J.G. Hanley; Ken Williams; Andreas Festa; Lynne E. Wagenknecht; Ralph B. D’Agostino, Jr; Steven M. Haffner
Diabetes November 2005, Vol.54, 3140-3147. doi:https://doi.org/10.2337/diabetes.54.11.3140
Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic Patients
Mandeep Bajaj; Swangjit Suraamornkul; Anthony Romanelli; Gary W. Cline; Lawrence J. Mandarino; Gerald I. Shulman; Ralph A. DeFronzo
Diabetes November 2005, Vol.54, 3148-3153. doi:https://doi.org/10.2337/diabetes.54.11.3148
Signal Transduction
Insulin-Stimulated Glucose Uptake Does Not Require p38 Mitogen-Activated Protein Kinase in Adipose Tissue or Skeletal Muscle
Sophie Turban; Victoria A. Beardmore; Julia M. Carr; Kei Sakamoto; Eric Hajduch; J. Simon C. Arthur; Harinder S. Hundal
Diabetes November 2005, Vol.54, 3161-3168. doi:https://doi.org/10.2337/diabetes.54.11.3161
Activation of ATP-Sensitive K+ Channels in the Ventromedial Hypothalamus Amplifies Counterregulatory Hormone Responses to Hypoglycemia in Normal and Recurrently Hypoglycemic Rats
Rory J. McCrimmon; Mark L. Evans; Xiaoning Fan; Ewan C. McNay; Owen Chan; Yuyan Ding; Wanling Zhu; Dorte X. Gram; Robert S. Sherwin
Diabetes November 2005, Vol.54, 3169-3174. doi:https://doi.org/10.2337/diabetes.54.11.3169
Impaired Generation of Reactive Oxygen Species in Leprechaunism Through Downregulation of Nox4
Hye Sun Park; Dong Kyu Jin; Sang Min Shin; Mi Kyung Jang; Nicholas Longo; Ji Won Park; Duk Soo Bae; Yun Soo Bae
Diabetes November 2005, Vol.54, 3175-3181. doi:https://doi.org/10.2337/diabetes.54.11.3175
Obesity Studies
Central Leptin Acutely Reverses Diet-Induced Hepatic Insulin Resistance
Alessandro Pocai; Kimyata Morgan; Christoph Buettner; Roger Gutierrez-Juarez; Silvana Obici; Luciano Rossetti
Diabetes November 2005, Vol.54, 3182-3189. doi:https://doi.org/10.2337/diabetes.54.11.3182
Adipocyte Lipases and Defect of Lipolysis in Human Obesity
Dominique Langin; Andrea Dicker; Geneviève Tavernier; Johan Hoffstedt; Aline Mairal; Mikael Rydén; Erik Arner; Audrey Sicard; Christopher M. Jenkins; Nathalie Viguerie; Vanessa van Harmelen; Richard W. Gross; Cecilia Holm; Peter Arner
Diabetes November 2005, Vol.54, 3190-3197. doi:https://doi.org/10.2337/diabetes.54.11.3190
Peptide YY(3–36) Inhibits Morning, but Not Evening, Food Intake and Decreases Body Weight in Rhesus Macaques
Frank H. Koegler; Pablo J. Enriori; Sonja K. Billes; Diana L. Takahashi; Meghan S. Martin; Randall L. Clark; Anne E. Evans; Kevin L. Grove; Judy L. Cameron; Michael A. Cowley
Diabetes November 2005, Vol.54, 3198-3204. doi:https://doi.org/10.2337/diabetes.54.11.3198
Immunology and Transplantation
Islet Cell Hormonal Responses to Hypoglycemia After Human Islet Transplantation for Type 1 Diabetes
Michael R. Rickels; Mark H. Schutta; Rebecca Mueller; James F. Markmann; Clyde F. Barker; Ali Naji; Karen L. Teff
Diabetes November 2005, Vol.54, 3205-3211. doi:https://doi.org/10.2337/diabetes.54.11.3205
Exposure to Farming Environments in Early Life and Type 1 Diabetes: A Case-Control Study
Katja Radon; Doris Windstetter; Susanne Solfrank; Erika von Mutius; Dennis Nowak; Hans-Peter Schwarz; for the Chronic Autoimmune Disease and Contact to Animals (CAT) Study Group
Diabetes November 2005, Vol.54, 3212-3216. doi:https://doi.org/10.2337/diabetes.54.11.3212
Brief Genetics Reports
The Fatty Acid–Binding Protein-2 A54T Polymorphism Is Associated With Renal Disease in Patients With Type 2 Diabetes
Luis H. Canani; Clarissa Capp; Daniel P.K. Ng; Serena G.L. Choo; Ana Luiza Maia; Gustavo B. Nabinger; Kátia Santos; Daisy Crispim; Israel Roisemberg; Andrzej S. Krolewski; Jorge L. Gross
Diabetes November 2005, Vol.54, 3326-3330. doi:https://doi.org/10.2337/diabetes.54.11.3326
Risk of Diabetic Nephropathy in Type 1 Diabetes Is Associated With Functional Polymorphisms in RANTES Receptor Gene (CCR5): A Sex-Specific Effect
Wojciech M. Mlynarski; Grzegorz P. Placha; Pawel P. Wolkow; Jacek P. Bochenski; James H. Warram; Andrzej S. Krolewski
Diabetes November 2005, Vol.54, 3331-3335. doi:https://doi.org/10.2337/diabetes.54.11.3331
