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Issues
1 March 2005
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome
Diabetes March 2005, Vol.54, 591-602. doi:https://doi.org/10.2337/diabetes.54.3.591
Metabolism
Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes
Kitt Falk Petersen; Sylvie Dufour; Douglas Befroy; Michael Lehrke; Rosa E. Hendler; Gerald I. Shulman
Diabetes March 2005, Vol.54, 603-608. doi:https://doi.org/10.2337/diabetes.54.3.603
Fructose Normalizes Specific Counterregulatory Responses to Hypoglycemia in Patients With Type 1 Diabetes
Diabetes March 2005, Vol.54, 609-616. doi:https://doi.org/10.2337/diabetes.54.3.609
Calcineurin Does Not Mediate Exercise-Induced Increase in Muscle GLUT4
Diabetes March 2005, Vol.54, 624-628. doi:https://doi.org/10.2337/diabetes.54.3.624
Free Fatty Acid Regulation of Glucose-Dependent Intrinsic Oscillatory Lipolysis in Perifused Isolated Rat Adipocytes
Diabetes March 2005, Vol.54, 629-637. doi:https://doi.org/10.2337/diabetes.54.3.629
Munc18c Heterozygous Knockout Mice Display Increased Susceptibility for Severe Glucose Intolerance
Diabetes March 2005, Vol.54, 638-647. doi:https://doi.org/10.2337/diabetes.54.3.638
Differential Utilization of Saturated Palmitate and Unsaturated Oleate: Evidence From Cultured Myotubes
Diabetes March 2005, Vol.54, 648-656. doi:https://doi.org/10.2337/diabetes.54.3.648
Signal Transduction
The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes
Kentaro Ozawa; Mayuki Miyazaki; Munehide Matsuhisa; Katsura Takano; Yoshihisa Nakatani; Masahiro Hatazaki; Takashi Tamatani; Kazuya Yamagata; Jun-ichiro Miyagawa; Yasuko Kitao; Osamu Hori; Yoshimitsu Yamasaki; Satoshi Ogawa
Diabetes March 2005, Vol.54, 657-663. doi:https://doi.org/10.2337/diabetes.54.3.657
Obesity Studies
Differential Responses of Visceral and Subcutaneous Fat Depots to Nutrients
Francine H. Einstein; Gil Atzmon; Xiao-man Yang; Xiao-Hui Ma; Marielisa Rincon; Eric Rudin; Radhika Muzumdar; Nir Barzilai
Diabetes March 2005, Vol.54, 672-678. doi:https://doi.org/10.2337/diabetes.54.3.672
Caveolin-1 Expression Is Essential for Proper Nonshivering Thermogenesis in Brown Adipose Tissue
Diabetes March 2005, Vol.54, 679-686. doi:https://doi.org/10.2337/diabetes.54.3.679
Immunology and Transplantation
Long-Term Graft Function of Adult Rat and Human Islets Encapsulated in Novel Alginate-Based Microcapsules After Transplantation in Immunocompetent Diabetic Mice
Stephan Schneider; Peter J. Feilen; Frank Brunnenmeier; Timo Minnemann; Heiko Zimmermann; Ulrich Zimmermann; Matthias M. Weber
Diabetes March 2005, Vol.54, 687-693. doi:https://doi.org/10.2337/diabetes.54.3.687
Islet Studies
Matrix Metalloproteinases 2 and 9 Are Dispensable for Pancreatic Islet Formation and Function In Vivo
Diabetes March 2005, Vol.54, 694-701. doi:https://doi.org/10.2337/diabetes.54.3.694
β-Cell Secretory Dysfunction in the Pathogenesis of Low Birth Weight–Associated Diabetes: A Murine Model
Josep C. Jimenez-Chillaron; Marcelino Hernandez-Valencia; Carolyn Reamer; Simon Fisher; Allison Joszi; Michael Hirshman; Aysin Oge; Shana Walrond; Roberta Przybyla; Carol Boozer; Laurie J. Goodyear; Mary-Elizabeth Patti
Diabetes March 2005, Vol.54, 702-711. doi:https://doi.org/10.2337/diabetes.54.3.702
Overexpression of Cyclin D1 in Pancreatic β-Cells In Vivo Results in Islet Hyperplasia Without Hypoglycemia
Diabetes March 2005, Vol.54, 712-719. doi:https://doi.org/10.2337/diabetes.54.3.712
TAT-Mediated Neurogenin 3 Protein Transduction Stimulates Pancreatic Endocrine Differentiation In Vitro
Juan Domínguez-Bendala; Dagmar Klein; Melina Ribeiro; Camillo Ricordi; Luca Inverardi; Ricardo Pastori; Helena Edlund
Diabetes March 2005, Vol.54, 720-726. doi:https://doi.org/10.2337/diabetes.54.3.720
Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes
Silvia Del Guerra; Roberto Lupi; Lorella Marselli; Matilde Masini; Marco Bugliani; Simone Sbrana; Scilla Torri; Maria Pollera; Ugo Boggi; Franco Mosca; Stefano Del Prato; Piero Marchetti
Diabetes March 2005, Vol.54, 727-735. doi:https://doi.org/10.2337/diabetes.54.3.727
Pathophysiology
Effects of Sustained Insulin-Induced Hypoglycemia on Cardiovascular Autonomic Regulation in Type 1 Diabetes
Minna L. Koivikko; Pasi I. Salmela; K.E. Juhani Airaksinen; Juha S. Tapanainen; Aimo Ruokonen; Timo H. Mäkikallio; Heikki V. Huikuri
Diabetes March 2005, Vol.54, 744-750. doi:https://doi.org/10.2337/diabetes.54.3.744
Redistribution of Glucose From Skeletal Muscle to Adipose Tissue During Catch-Up Fat: A Link Between Catch-Up Growth and Later Metabolic Syndrome
Philippe Cettour-Rose; Sonia Samec; Aaron P. Russell; Serge Summermatter; Davide Mainieri; Claudia Carrillo-Theander; Jean-Pierre Montani; Josiane Seydoux; Françoise Rohner-Jeanrenaud; Abdul G. Dulloo
Diabetes March 2005, Vol.54, 751-756. doi:https://doi.org/10.2337/diabetes.54.3.751
Effect of Dehydroepiandrosterone Replacement on Insulin Sensitivity and Lipids in Hypoadrenal Women
Diabetes March 2005, Vol.54, 765-769. doi:https://doi.org/10.2337/diabetes.54.3.765
Contribution of Abdominal Visceral Obesity and Insulin Resistance to the Cardiovascular Risk Profile of Postmenopausal Women
Diabetes March 2005, Vol.54, 770-777. doi:https://doi.org/10.2337/diabetes.54.3.770
Absence of Heme Oxygenase-1 Exacerbates Myocardial Ischemia/Reperfusion Injury in Diabetic Mice
Diabetes March 2005, Vol.54, 778-784. doi:https://doi.org/10.2337/diabetes.54.3.778
Complications
Impaired Retinal Angiogenesis in Diabetes: Role of Advanced Glycation End Products and Galectin-3
Alan W. Stitt; Ciara McGoldrick; Aine Rice-McCaldin; David R. McCance; Josephine V. Glenn; Daniel K. Hsu; Fu-Tong Liu; Suzanne R. Thorpe; Tom A. Gardiner
Diabetes March 2005, Vol.54, 785-794. doi:https://doi.org/10.2337/diabetes.54.3.785
Hyperglycemia in Streptozotocin-Induced Diabetic Rat Increases Infarct Size Associated With Low Levels of Myocardial HO-1 During Ischemia/Reperfusion
Clara Di Filippo; Raffaele Marfella; Salvatore Cuzzocrea; Elena Piegari; Pasquale Petronella; Dario Giugliano; Francesco Rossi; Michele D’Amico
Diabetes March 2005, Vol.54, 803-810. doi:https://doi.org/10.2337/diabetes.54.3.803
Requirement of Aldose Reductase for the Hyperglycemic Activation of Protein Kinase C and Formation of Diacylglycerol in Vascular Smooth Muscle Cells
Kota V. Ramana; Brian Friedrich; Ravinder Tammali; Matthew B. West; Aruni Bhatnagar; Satish K. Srivastava
Diabetes March 2005, Vol.54, 818-829. doi:https://doi.org/10.2337/diabetes.54.3.818
Experimental Diabetic Neuropathy With Spontaneous Recovery: Is There Irreparable Damage?
Diabetes March 2005, Vol.54, 830-837. doi:https://doi.org/10.2337/diabetes.54.3.830
N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Prevents Renal Insufficiency and Mesangial Matrix Expansion in Diabetic db/db Mice
Kazuyuki Shibuya; Keizo Kanasaki; Motohide Isono; Haruhisa Sato; Mitsugu Omata; Toshiro Sugimoto; Shin-ichi Araki; Keiji Isshiki; Atsunori Kashiwagi; Masakazu Haneda; Daisuke Koya
Diabetes March 2005, Vol.54, 838-845. doi:https://doi.org/10.2337/diabetes.54.3.838
Nonviral Gene Transfer of Human Hepatocyte Growth Factor Improves Streptozotocin-Induced Diabetic Neuropathy in Rats
Naoki Kato; Koichi Nemoto; Kuniaki Nakanishi; Ryuichi Morishita; Yasufumi Kaneda; Maki Uenoyama; Tomosumi Ikeda; Kyosuke Fujikawa
Diabetes March 2005, Vol.54, 846-854. doi:https://doi.org/10.2337/diabetes.54.3.846
Topical Pretreatment of Diabetic Rats With All-trans Retinoic Acid Improves Healing of Subsequently Induced Abrasion Wounds
Diabetes March 2005, Vol.54, 855-861. doi:https://doi.org/10.2337/diabetes.54.3.855
Pharmacology and Therapeutics
Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs
Marilyn Ader; Stella P. Kim; Karyn J. Catalano; Viorica Ionut; Katrin Hucking; Joyce M. Richey; Morvarid Kabir; Richard N. Bergman
Diabetes March 2005, Vol.54, 862-871. doi:https://doi.org/10.2337/diabetes.54.3.862
Increased In Vivo Regeneration of Cortisol in Adipose Tissue in Human Obesity and Effects of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Carbenoxolone
Thekkepat C. Sandeep; Ruth Andrew; Natalie Z.M. Homer; Robert C. Andrews; Ken Smith; Brian R. Walker
Diabetes March 2005, Vol.54, 872-879. doi:https://doi.org/10.2337/diabetes.54.3.872
Thiazolidinediones Upregulate Fatty Acid Uptake and Oxidation in Adipose Tissue of Diabetic Patients
Diabetes March 2005, Vol.54, 880-885. doi:https://doi.org/10.2337/diabetes.54.3.880
Genetics
Association Testing of Variants in the Hepatocyte Nuclear Factor 4α Gene With Risk of Type 2 Diabetes in 7,883 People
Wendy Winckler; Robert R. Graham; Paul I.W. de Bakker; Maria Sun; Peter Almgren; Tiinamaija Tuomi; Daniel Gaudet; Thomas J. Hudson; Kristin G. Ardlie; Mark J. Daly; Joel N. Hirschhorn; Leif Groop; David Altshuler
Diabetes March 2005, Vol.54, 886-892. doi:https://doi.org/10.2337/diabetes.54.3.886
Brief Genetics Reports
Retrovirus-Like Long-Terminal Repeat DQ-LTR13 and Genetic Susceptibility to Type 1 Diabetes and Autoimmune Addison’s Disease
Giovanni Gambelunghe; Ingrid Kockum; Vittorio Bini; Giovanni De Giorgi; Federica Celi; Corrado Betterle; Roberta Giordano; Rossella Libè; Alberto Falorni; on behalf of the Umbria Type 1 Diabetes Registry and the Italian Addison Network
Diabetes March 2005, Vol.54, 900-905. doi:https://doi.org/10.2337/diabetes.54.3.900
Genetic Association Between a Lymphoid Tyrosine Phosphatase (PTPN22) and Type 1 Diabetes
Diabetes March 2005, Vol.54, 906-908. doi:https://doi.org/10.2337/diabetes.54.3.906
Genome-wide Linkage Scans for Fasting Glucose, Insulin, and Insulin Resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: Evidence of Linkages to Chromosome 7q36 and 19q13 From Meta-Analysis
Ping An; Barry I. Freedman; Craig L. Hanis; Yii-Der I. Chen; Alan B. Weder; Nicholas J. Schork; Eric Boerwinkle; Michael A. Province; Chao Agnes Hsiung; Xiaodong Wu; Thomas Quertermous; D.C. Rao
Diabetes March 2005, Vol.54, 909-914. doi:https://doi.org/10.2337/diabetes.54.3.909
