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Issues
1 July 2005
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Nutritional Epigenomics of Metabolic Syndrome: New Perspective Against the Epidemic
Diabetes July 2005, Vol.54, 1899-1906. doi:https://doi.org/10.2337/diabetes.54.7.1899
Metabolism
Effect of Fructose Overfeeding and Fish Oil Administration on Hepatic De Novo Lipogenesis and Insulin Sensitivity in Healthy Men
Diabetes July 2005, Vol.54, 1907-1913. doi:https://doi.org/10.2337/diabetes.54.7.1907
Assessing the Predictive Accuracy of QUICKI as a Surrogate Index for Insulin Sensitivity Using a Calibration Model
Diabetes July 2005, Vol.54, 1914-1925. doi:https://doi.org/10.2337/diabetes.54.7.1914
A High-Fat Diet Coordinately Downregulates Genes Required for Mitochondrial Oxidative Phosphorylation in Skeletal Muscle
Lauren M. Sparks; Hui Xie; Robert A. Koza; Randall Mynatt; Matthew W. Hulver; George A. Bray; Steven R. Smith
Diabetes July 2005, Vol.54, 1926-1933. doi:https://doi.org/10.2337/diabetes.54.7.1926
A Multicompartmental Model of In Vivo Adipose Tissue Glycerol Kinetics and Capillary Permeability in Lean and Obese Humans
Diabetes July 2005, Vol.54, 1934-1941. doi:https://doi.org/10.2337/diabetes.54.7.1934
Obesity and Type 2 Diabetes Impair Insulin-Induced Suppression of Glycogenolysis as Well as Gluconeogenesis
Diabetes July 2005, Vol.54, 1942-1948. doi:https://doi.org/10.2337/diabetes.54.7.1942
Signal Transduction
Impact of the Liver-Specific Expression of SHIP2 (SH2-Containing Inositol 5′-Phosphatase 2) on Insulin Signaling and Glucose Metabolism in Mice
Kazuhito Fukui; Tsutomu Wada; Syota Kagawa; Kiyofumi Nagira; Mariko Ikubo; Hajime Ishihara; Masashi Kobayashi; Toshiyasu Sasaoka
Diabetes July 2005, Vol.54, 1958-1967. doi:https://doi.org/10.2337/diabetes.54.7.1958
Role of Upstream Stimulatory Factors in Regulation of Renal Transforming Growth Factor-β1
Diabetes July 2005, Vol.54, 1976-1984. doi:https://doi.org/10.2337/diabetes.54.7.1976
Obesity Studies
Distinct Forebrain and Caudal Brainstem Contributions to the Neuropeptide Y Mediation of Ghrelin Hyperphagia
Diabetes July 2005, Vol.54, 1985-1993. doi:https://doi.org/10.2337/diabetes.54.7.1985
Long-Term Efficacy of Leptin Replacement in Patients With Generalized Lipodystrophy
Diabetes July 2005, Vol.54, 1994-2002. doi:https://doi.org/10.2337/diabetes.54.7.1994
Autocrine Action of Adiponectin on Human Fat Cells Prevents the Release of Insulin Resistance-Inducing Factors
Diabetes July 2005, Vol.54, 2003-2011. doi:https://doi.org/10.2337/diabetes.54.7.2003
Role of Selective Leptin Resistance in Diet-Induced Obesity Hypertension
Diabetes July 2005, Vol.54, 2012-2018. doi:https://doi.org/10.2337/diabetes.54.7.2012
NOD B-cells Are Insufficient to Incite T-Cell-Mediated Anti-islet Autoimmunity
Diabetes July 2005, Vol.54, 2019-2025. doi:https://doi.org/10.2337/diabetes.54.7.2019
Immunology and Transplantation
Maternal Factors in a Model of Type 1 Diabetes Differentially Affect the Development of Insulitis and Overt Diabetes in Offspring
Diabetes July 2005, Vol.54, 2026-2031. doi:https://doi.org/10.2337/diabetes.54.7.2026
The Influence of the Major Histocompatibility Complex on Development of Autoimmune Diabetes in RIP-B7.1 Mice
Diabetes July 2005, Vol.54, 2032-2040. doi:https://doi.org/10.2337/diabetes.54.7.2032
Identification of Naturally Processed HLA-A2—Restricted Proinsulin Epitopes by Reverse Immunology
Yousra Hassainya; Francisco Garcia-Pons; Roland Kratzer; Vivian Lindo; Fiona Greer; François A. Lemonnier; Gabriele Niedermann; Peter M. van Endert
Diabetes July 2005, Vol.54, 2053-2059. doi:https://doi.org/10.2337/diabetes.54.7.2053
Five-Year Follow-Up After Clinical Islet Transplantation
Edmond A. Ryan; Breay W. Paty; Peter A. Senior; David Bigam; Eman Alfadhli; Norman M. Kneteman; Jonathan R.T. Lakey; A.M. James Shapiro
Diabetes July 2005, Vol.54, 2060-2069. doi:https://doi.org/10.2337/diabetes.54.7.2060
Islet Studies
Saturated and cis/trans Unsaturated Acyl CoA Esters Differentially Regulate Wild-Type and Polymorphic β-Cell ATP-Sensitive K+ Channels
Diabetes July 2005, Vol.54, 2070-2079. doi:https://doi.org/10.2337/diabetes.54.7.2070
Role for β1 Integrin and Its Associated α3, α5, and α6 Subunits in Development of the Human Fetal Pancreas
Diabetes July 2005, Vol.54, 2080-2089. doi:https://doi.org/10.2337/diabetes.54.7.2080
Targeted Inactivation of Hepatocyte Growth Factor Receptor c-met in β-Cells Leads to Defective Insulin Secretion and GLUT-2 Downregulation Without Alteration of β-Cell Mass
Jennifer Roccisana; Vasumathi Reddy; Rupangi C. Vasavada; Jose A. Gonzalez-Pertusa; Mark A. Magnuson; Adolfo Garcia-Ocaña
Diabetes July 2005, Vol.54, 2090-2102. doi:https://doi.org/10.2337/diabetes.54.7.2090
Peptide-Mediated Targeting of the Islets of Langerhans
Kausar N. Samli; Michael J. McGuire; Christopher B. Newgard; Stephen Albert Johnston; Kathlynn C. Brown
Diabetes July 2005, Vol.54, 2103-2108. doi:https://doi.org/10.2337/diabetes.54.7.2103
Overexpression of Glutathione Peroxidase With Two Isoforms of Superoxide Dismutase Protects Mouse Islets From Oxidative Injury and Improves Islet Graft Function
Tharun B. Mysore; Trixie A. Shinkel; James Collins; Evelyn J. Salvaris; Nella Fisicaro; Lisa J. Murray-Segal; Lucinda E.A. Johnson; Diana A. Lepore; Stacey N. Walters; Rebecca Stokes; Abhilash P. Chandra; Philip J. O’Connell; Anthony J.F. d’Apice; Peter J. Cowan
Diabetes July 2005, Vol.54, 2109-2116. doi:https://doi.org/10.2337/diabetes.54.7.2109
Aberrant Processing of Human Proislet Amyloid Polypeptide Results in Increased Amyloid Formation
Diabetes July 2005, Vol.54, 2117-2125. doi:https://doi.org/10.2337/diabetes.54.7.2117
Inhibition of Purinoceptors Amplifies Glucose-Stimulated Insulin Release With Removal of its Pulsatility
Diabetes July 2005, Vol.54, 2126-2131. doi:https://doi.org/10.2337/diabetes.54.7.2126
Complications
Tissue Factor as a Link Between Wounding and Tissue Repair
Jiang Chen; Michael Kasper; Tobias Heck; Katsumi Nakagawa; Per M. Humpert; Ling Bai; Gang Wu; Youming Zhang; Thomas Luther; Martin Andrassy; Stephan Schiekofer; Andreas Hamann; Michael Morcos; Baoshen Chen; David M. Stern; Peter P. Nawroth; Angelika Bierhaus
Diabetes July 2005, Vol.54, 2143-2154. doi:https://doi.org/10.2337/diabetes.54.7.2143
Impaired Arachidonic Acid–Mediated Activation of Large-Conductance Ca2+-Activated K+ Channels in Coronary Arterial Smooth Muscle Cells in Zucker Diabetic Fatty Rats
Tong Lu; Xiao-Li Wang; Tongrong He; Wei Zhou; Terry L. Kaduce; Zvonimir S. Katusic; Arthur A. Spector; Hon-Chi Lee
Diabetes July 2005, Vol.54, 2155-2163. doi:https://doi.org/10.2337/diabetes.54.7.2155
The Early Natural History of Nephropathy in Type 1 Diabetes: III. Predictors of 5-Year Urinary Albumin Excretion Rate Patterns in Initially Normoalbuminuric Patients
Julia M. Steinke; Alan R. Sinaiko; Michael S. Kramer; Samy Suissa; Blanche M. Chavers; Michael Mauer; for the International Diabetic Nephropathy Study Group
Diabetes July 2005, Vol.54, 2164-2171. doi:https://doi.org/10.2337/diabetes.54.7.2164
Heparanase-1 Gene Expression and Regulation by High Glucose in Renal Epithelial Cells : A Potential Role in the Pathogenesis of Proteinuria in Diabetic Patients
Justin B. Maxhimer; Michael Somenek; Geetha Rao; Catherine E. Pesce; David Baldwin, Jr.; Paolo Gattuso; Melvin M. Schwartz; Edmund J. Lewis; Richard A. Prinz; Xiulong Xu
Diabetes July 2005, Vol.54, 2172-2178. doi:https://doi.org/10.2337/diabetes.54.7.2172
Metformin Prevents High-Glucose–Induced Endothelial Cell Death Through a Mitochondrial Permeability Transition-Dependent Process
Dominique Detaille; Bruno Guigas; Christiane Chauvin; Cécile Batandier; Eric Fontaine; Nicolas Wiernsperger; Xavier Leverve
Diabetes July 2005, Vol.54, 2179-2187. doi:https://doi.org/10.2337/diabetes.54.7.2179
The Effect of Ruboxistaurin on Visual Loss in Patients With Moderately Severe to Very Severe Nonproliferative Diabetic Retinopathy : Initial Results of the Protein Kinase C β Inhibitor Diabetic Retinopathy Study (PKC-DRS) Multicenter Randomized Clinical Trial
Diabetes July 2005, Vol.54, 2188-2197. doi:https://doi.org/10.2337/diabetes.54.7.2188
Advanced Glycation End Product Precursors Impair ABCA1-Dependent Cholesterol Removal From Cells
Marisa Passarelli; Chongren Tang; Thomas O. McDonald; Kevin D. O’Brien; Ross G. Gerrity; Jay W. Heinecke; John F. Oram
Diabetes July 2005, Vol.54, 2198-2205. doi:https://doi.org/10.2337/diabetes.54.7.2198
Pharmacology and Therapeutics
Long-Term Treatment With Rosiglitazone and Metformin Reduces the Extent of, but Does Not Prevent, Islet Amyloid Deposition in Mice Expressing the Gene for Human Islet Amyloid Polypeptide
Rebecca L. Hull; Zhen-Ping Shen; Melissah R. Watts; Keiichi Kodama; Darcy B. Carr; Kristina M. Utzschneider; Sakeneh Zraika; Feng Wang; Steven E. Kahn
Diabetes July 2005, Vol.54, 2235-2244. doi:https://doi.org/10.2337/diabetes.54.7.2235
Brief Genetics Reports
Genetic Variation in Adiponectin Receptor 1 and Adiponectin Receptor 2 Is Associated With Type 2 Diabetes in the Old Order Amish
Coleen M. Damcott; Sandra H. Ott; Toni I. Pollin; Laurie J. Reinhart; Jian Wang; Jeffrey R. O’Connell; Braxton D. Mitchell; Alan R. Shuldiner
Diabetes July 2005, Vol.54, 2245-2250. doi:https://doi.org/10.2337/diabetes.54.7.2245
Hepatic Lipase Gene Variant −514C>T Is Associated With Lipoprotein and Insulin Sensitivity Response to Regular Exercise: The HERITAGE Family Study
Margarita Teran-Garcia; Nicola Santoro; Tuomo Rankinen; Jean Bergeron; Treva Rice; Arthur S. Leon; D.C. Rao; James S. Skinner; Richard N. Bergman; Jean-Pierre Després; Claude Bouchard
Diabetes July 2005, Vol.54, 2251-2255. doi:https://doi.org/10.2337/diabetes.54.7.2251
Polymorphisms in the SLC2A2 (GLUT2) Gene Are Associated With the Conversion From Impaired Glucose Tolerance to Type 2 Diabetes : The Finnish Diabetes Prevention Study
Olli Laukkanen; Jaana Lindström; Johan Eriksson; Timo T. Valle; Helena Hämäläinen; Pirjo Ilanne-Parikka; Sirkka Keinänen-Kiukaanniemi; Jaakko Tuomilehto; Matti Uusitupa; Markku Laakso
Diabetes July 2005, Vol.54, 2256-2260. doi:https://doi.org/10.2337/diabetes.54.7.2256
Evidence of an Association Between the Arg72 Allele of the Peptide YY and Increased Risk of Type 2 Diabetes
Signe S. Torekov; Lesli H. Larsen; Charlotte Glümer; Knut Borch-Johnsen; Torben Jørgensen; Jens J. Holst; Ole D. Madsen; Torben Hansen; Oluf Pedersen
Diabetes July 2005, Vol.54, 2261-2265. doi:https://doi.org/10.2337/diabetes.54.7.2261
