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Issues
February 2006
ISSN 0012-1797
EISSN 1939-327X
Rapid Publication
Regeneration of Pancreatic Islets After Partial Pancreatectomy in Mice Does Not Involve the Reactivation of Neurogenin-3
Diabetes February 2006, Vol.55, 269-272. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1300
Obesity Studies
Inhibition of p38MAPK Increases Adipogenesis From Embryonic to Adult Stages
Myriam Aouadi; Kathiane Laurent; Matthieu Prot; Yannick Le Marchand-Brustel; Bernard Binétruy; Frédéric Bost
Diabetes February 2006, Vol.55, 281-289. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0963
MCH−/− Mice Are Resistant to Aging-Associated Increases in Body Weight and Insulin Resistance
Justin Y. Jeon; Richard L. Bradley; Efi G. Kokkotou; Francis E. Marino; Xiaomei Wang; Pavlos Pissios; Eleftheria Maratos-Flier
Diabetes February 2006, Vol.55, 428-434. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0203
Immunology and Transplantation
Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic β-Cell Fate
Jalal Taneera; Anders Rosengren; Erik Renstrom; Jens M. Nygren; Palle Serup; Patrik Rorsman; Sten Eirik W. Jacobsen
Diabetes February 2006, Vol.55, 290-296. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1212
Islet Studies
MafB: An Activator of the Glucagon Gene Expressed in Developing Islet α- and β-Cells
Isabella Artner; John Le Lay; Yan Hang; Lynda Elghazi; Jonathan C. Schisler; Eva Henderson; Beatriz Sosa-Pineda; Roland Stein
Diabetes February 2006, Vol.55, 297-304. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0946
CART Regulates Islet Hormone Secretion and Is Expressed in the β-Cells of Type 2 Diabetic Rats
Diabetes February 2006, Vol.55, 305-311. doi:https://doi.org/10.2337/diabetes.55.02.06.db04-1383
Integrin Signaling via RGD Peptides and Anti-β1 Antibodies Confers Resistance to Apoptosis in Islets of Langerhans
Gabrielle G.M. Pinkse; Wendy P. Bouwman; Reshma Jiawan-Lalai; O.T. Terpstra; Jan A. Bruijn; Emile de Heer
Diabetes February 2006, Vol.55, 312-317. doi:https://doi.org/10.2337/diabetes.55.02.06.db04-0195
Akt Induces β-Cell Proliferation by Regulating Cyclin D1, Cyclin D2, and p21 Levels and Cyclin-Dependent Kinase-4 Activity
Szabolcs Fatrai; Lynda Elghazi; Norman Balcazar; Corentin Cras-Méneur; Irina Krits; Hiroaki Kiyokawa; Ernesto Bernal-Mizrachi
Diabetes February 2006, Vol.55, 318-325. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0757
Differences of Pancreatic Expression of 7B2 Between C57BL/6J and C3H/HeJ Mice and Genetic Polymorphisms at its locus (Sgne1)
Gunther Schmidt; Francine Sirois; Younes Anini; Lisa M. Kauri; Charles Gyamera-Acheampong; Eckart Fleck; Fraser W. Scott; Michel Chrétien; Majambu Mbikay
Diabetes February 2006, Vol.55, 452-459. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0733
Pathophysiology
Effects of Type 1 Diabetes on Gray Matter Density as Measured by Voxel-Based Morphometry
Gail Musen; In Kyoon Lyoo; Caitlin R. Sparks; Katie Weinger; Jaeuk Hwang; Christopher M. Ryan; David C. Jimerson; John Hennen; Perry F. Renshaw; Alan M. Jacobson
Diabetes February 2006, Vol.55, 326-333. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0520
Microvascular Disease in Type 1 Diabetes Alters Brain Activation: A Functional Magnetic Resonance Imaging Study
Alette M. Wessels; Serge A.R.B. Rombouts; Suat Simsek; Joost P.A. Kuijer; Piet J. Kostense; Frederik Barkhof; Philip Scheltens; Frank J. Snoek; Robert J. Heine
Diabetes February 2006, Vol.55, 334-340. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0680
Gestational Glucose Tolerance and Risk of Type 2 Diabetes in Young Pima Indian Offspring
Paul W. Franks; Helen C. Looker; Sayuko Kobes; Leslie Touger; P. Antonio Tataranni; Robert L. Hanson; William C. Knowler
Diabetes February 2006, Vol.55, 460-465. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0823
Increased Myocardial Oxygen Consumption Reduces Cardiac Efficiency in Diabetic Mice
Diabetes February 2006, Vol.55, 466-473. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1164
Complications
ACE Inhibitor or Angiotensin II Receptor Antagonist Attenuates Diabetic Neuropathy in Streptozotocin-Induced Diabetic Rats
Lawrence J. Coppey; Eric P. Davidson; Thomas W. Rinehart; Jill S. Gellett; Christine L. Oltman; Donald D. Lund; Mark A. Yorek
Diabetes February 2006, Vol.55, 341-348. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0885
Streptozotocin-Induced Diabetes Causes Astrocyte Death After Ischemia and Reperfusion Injury
Diabetes February 2006, Vol.55, 349-355. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0654
A Severe Diabetic Nephropathy Model With Early Development of Nodule-Like Lesions Induced by Megsin Overexpression in RAGE/iNOS Transgenic Mice
Reiko Inagi; Yasuhiko Yamamoto; Masaomi Nangaku; Nobuteru Usuda; Hiroshi Okamato; Kiyoshi Kurokawa; Charles van Ypersele de Strihou; Hiroshi Yamamoto; Toshio Miyata
Diabetes February 2006, Vol.55, 356-366. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0702
Statins Prevent Dextrose-Induced Endothelial Barrier Dysfunction, Possibly Through Inhibition of Superoxide Formation
Diabetes February 2006, Vol.55, 474-479. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1078
Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo
Max Nieuwdorp; Timon W. van Haeften; Mirella C.L.G. Gouverneur; Hans L. Mooij; Miriam H.P. van Lieshout; Marcel Levi; Joost C.M. Meijers; Frits Holleman; Joost B.L. Hoekstra; Hans Vink; John J.P. Kastelein; Erik S.G. Stroes
Diabetes February 2006, Vol.55, 480-486. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1103
Diabetes Enhances mRNA Levels of Proapoptotic Genes and Caspase Activity, Which Contribute to Impaired Healing
Diabetes February 2006, Vol.55, 487-495. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1201
Activation of the AMP-Activated Kinase by Antidiabetes Drug Metformin Stimulates Nitric Oxide Synthesis In Vivo by Promoting the Association of Heat Shock Protein 90 and Endothelial Nitric Oxide Synthase
Diabetes February 2006, Vol.55, 496-505. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1064
Retinal Vessel Diameters and Risk of Impaired Fasting Glucose or Diabetes: The Rotterdam Study
M. Kamran Ikram; Joop A.M.J.L. Janssen; Anna M.E. Roos; Ingrid Rietveld; Jacqueline C.M. Witteman; Monique M.B. Breteler; Albert Hofman; Cornelia M. van Duijn; Paulus T.V.M. de Jong
Diabetes February 2006, Vol.55, 506-510. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0546
Pharmacology and Therapeutics
Angiotensin II Type 1 Receptor Blockade Improves β-Cell Function and Glucose Tolerance in a Mouse Model of Type 2 Diabetes
Diabetes February 2006, Vol.55, 367-374. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1022
Insulin Improves Myocardial Blood Flow in Patients With Type 2 Diabetes and Coronary Artery Disease
Riikka Lautamäki; K.E. Juhani Airaksinen; Marko Seppänen; Jyri Toikka; Risto Härkönen; Matti Luotolahti; Ronald Borra; Jan Sundell; Juhani Knuuti; Pirjo Nuutila
Diabetes February 2006, Vol.55, 511-516. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1023
Effect of Pioglitazone on Pancreatic β-Cell Function and Diabetes Risk in Hispanic Women With Prior Gestational Diabetes
Anny H. Xiang; Ruth K. Peters; Siri L. Kjos; Aura Marroquin; Jose Goico; Cesar Ochoa; Miwa Kawakubo; Thomas A. Buchanan
Diabetes February 2006, Vol.55, 517-522. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1066
Genetics
Genetic Architecture of the APM1 Gene and Its Influence on Adiponectin Plasma Levels and Parameters of the Metabolic Syndrome in 1,727 Healthy Caucasians
Iris M. Heid; Stefanie A. Wagner; Henning Gohlke; Bernhard Iglseder; Jakob C. Mueller; Paula Cip; Günther Ladurner; Raphael Reiter; Andreas Stadlmayr; Vitolds Mackevics; Thomas Illig; Florian Kronenberg; Bernhard Paulweber
Diabetes February 2006, Vol.55, 375-384. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0747
Interactions Between Noncontiguous Haplotypes in the Adiponectin Gene ACDC Are Associated With Plasma Adiponectin
Jessica G. Woo; Lawrence M. Dolan; Ranjan Deka; Ritesh D. Kaushal; Yayun Shen; Prodipto Pal; Stephen R. Daniels; Lisa J. Martin
Diabetes February 2006, Vol.55, 523-529. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0446
Hemostatic Markers of Endothelial Dysfunction and Risk of Incident Type 2 Diabetes: The Framingham Offspring Study
James B. Meigs; Christopher J. O’Donnell; Geoffrey H. Tofler; Emelia J. Benjamin; Caroline S. Fox; Izabela Lipinska; David M. Nathan; Lisa M. Sullivan; Ralph B. D’Agostino; Peter W.F. Wilson
Diabetes February 2006, Vol.55, 530-537. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1041
Defective Induction of CTLA-4 in the NOD Mouse Is Controlled by the NOD Allele of Idd3/IL-2 and a Novel Locus (Ctex) Telomeric on Chromosome 1
Marie Lundholm; Vinicius Motta; Anna Löfgren-Burström; Nadia Duarte; Marie-Louise Bergman; Sofia Mayans; Dan Holmberg
Diabetes February 2006, Vol.55, 538-544. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1240
Brief Genetics Reports
Identification of TUB as a Novel Candidate Gene Influencing Body Weight in Humans
Ronit Shiri-Sverdlov; Anne Custers; Jana V. van Vliet-Ostaptchouk; Patrick J.J. van Gorp; Patrick J. Lindsey; Jonathan H.O. van Tilburg; Sasha Zhernakova; Edith J.M. Feskens; Daphne L. van der A; Martijn E.T. Dollé; Timon W. van Haeften; Bobby P.C. Koeleman; Marten H. Hofker; Cisca Wijmenga
Diabetes February 2006, Vol.55, 385-389. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0997
ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity
Nabila Bouatia-Naji; David Meyre; Stéphane Lobbens; Karin Séron; Frédéric Fumeron; Beverley Balkau; Barbara Heude; Béatrice Jouret; Philipp E. Scherer; Christian Dina; Jacques Weill; Philippe Froguel
Diabetes February 2006, Vol.55, 545-550. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0971
Quantitative Trait Loci on Chromosome 8q24 for Pancreatic β-Cell Function and 7q11 for Insulin Sensitivity in Obese Nondiabetic White and Black Families: Evidence From Genome-Wide Linkage Scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) Study
Ping An; Barry I. Freedman; Stephen S. Rich; Stephen A. Mandel; Donna K. Arnett; Richard H. Myers; Yii-Der I. Chen; Steven C. Hunt; D.C. Rao
Diabetes February 2006, Vol.55, 551-558. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0714
Analysis of Polymorphisms of the Interleukin-18 Gene in Type 1 Diabetes and Hardy-Weinberg Equilibrium Testing
Jeffrey S. Szeszko; Joanna M.M. Howson; Jason D. Cooper; Neil M. Walker; Rebecca C.J. Twells; Helen E. Stevens; Sarah L. Nutland; John A. Todd
Diabetes February 2006, Vol.55, 559-562. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0826
New Methodologies and Databases
Considerations in the Design of Hyperinsulinemic-Euglycemic Clamps in the Conscious Mouse
Diabetes February 2006, Vol.55, 390-397. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0686
Metabolism
Cholinergic Involvement in Vascular and Glucoregulatory Actions of Insulin in Rats
Diabetes February 2006, Vol.55, 398-404. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0684
Contrasting Insulin Sensitivity of Endogenous Glucose Production Rate in Subjects With Hepatocyte Nuclear Factor-1β and -1α Mutations
Anna Brackenridge; Ewan R. Pearson; Fariba Shojaee-Moradie; Andrew T. Hattersley; David Russell-Jones; A. Margot Umpleby
Diabetes February 2006, Vol.55, 405-411. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1019
Signal Transduction
Glucokinase Is a Critical Regulator of Ventromedial Hypothalamic Neuronal Glucosensing
Ling Kang; Ambrose A. Dunn-Meynell; Vanessa H. Routh; Larry D. Gaspers; Yasufumi Nagata; Teruyuki Nishimura; Junichi Eiki; Bei B. Zhang; Barry E. Levin
Diabetes February 2006, Vol.55, 412-420. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-1229
SGK1 Kinase Upregulates GLUT1 Activity and Plasma Membrane Expression
Monica Palmada; Christoph Boehmer; Ahmad Akel; Jeyaganesh Rajamanickam; Sankarganesh Jeyaraj; Konrad Keller; Florian Lang
Diabetes February 2006, Vol.55, 421-427. doi:https://doi.org/10.2337/diabetes.55.02.06.db05-0720
Erratum
Erratum
Diabetes February 2006, Vol.55, 563. doi:https://doi.org/10.2337/diabetes.55.02.06.db06-er02
