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Editorial
New Editorial Team, Diabetes Journal
Diabetes January 2007, Vol.56, 1-2. doi:https://doi.org/10.2337/db07-9900
Rapid Publications
Islet-Derived Fibroblast-Like Cells Are Not Derived via Epithelial-Mesenchymal Transition From Pdx-1 or Insulin-Positive Cells
Topics:
dna
,
epithelial to mesenchymal transition
,
fibroblasts
,
insulin
,
mice
Diabetes January 2007, Vol.56, 3-7. doi:https://doi.org/10.2337/db06-1165
Obesity Studies
Liraglutide, a Long-Acting Glucagon-Like Peptide-1 Analog, Reduces Body Weight and Food Intake in Obese Candy-Fed Rats, Whereas a Dipeptidyl Peptidase-IV Inhibitor, Vildagliptin, Does Not
Kirsten Raun; Pia von Voss; Carsten F. Gotfredsen; Valeria Golozoubova; Bidda Rolin; Lotte Bjerre Knudsen
Topics:
candy
,
glucagon-like peptide 1
,
liraglutide
,
obesity
,
oral glucose tolerance test
Diabetes January 2007, Vol.56, 8-15. doi:https://doi.org/10.2337/db06-0565
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
Topics:
adipose tissue
,
diet
,
diet, high-fat
,
genes
,
macrophages
Diabetes January 2007, Vol.56, 16-23. doi:https://doi.org/10.2337/db06-1076
Involvement of Apolipoprotein E in Excess Fat Accumulation and Insulin Resistance
Junhong Gao; Hideki Katagiri; Yasushi Ishigaki; Tetsuya Yamada; Takehide Ogihara; Junta Imai; Kenji Uno; Yutaka Hasegawa; Makoto Kanzaki; Tokuo T. Yamamoto; Shun Ishibashi; Yoshitomo Oka
Topics:
apolipoprotein e
,
mice
,
obesity
,
lipoproteins, vldl
,
adipocytes
Diabetes January 2007, Vol.56, 24-33. doi:https://doi.org/10.2337/db06-0144
Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein β Are Protected Against Diet-Induced Obesity
Carrie A. Millward; Jason D. Heaney; David S. Sinasac; Eric C. Chu; Ilya R. Bederman; Danielle A. Gilge; Stephen F. Previs; Colleen M. Croniger
Topics:
diet, high-fat
,
mice
,
obesity
,
diet
,
carbon dioxide
Diabetes January 2007, Vol.56, 161-167. doi:https://doi.org/10.2337/db06-0310
Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period
Alex S.T. Bickerton; Rachel Roberts; Barbara A. Fielding; Leanne Hodson; Ellen E. Blaak; Anton J.M. Wagenmakers; Marjorie Gilbert; Fredrik Karpe; Keith N. Frayn
Topics:
adipose tissue
,
fatty acids
,
nonesterified fatty acids
,
palmitates
,
triglycerides
Diabetes January 2007, Vol.56, 168-176. doi:https://doi.org/10.2337/db06-0822
Immunology and Transplantation
RegII Is a β-Cell Protein and Autoantigen in Diabetes of NOD Mice
Topics:
mice
,
mice, inbred nod
,
t-lymphocytes
,
vaccination
,
immunization
Diabetes January 2007, Vol.56, 34-40. doi:https://doi.org/10.2337/db06-0669
Crystal Structure of the Major Diabetes Autoantigen Insulinoma-Associated Protein 2 Reveals Distinctive Immune Epitopes
Topics:
antibodies
,
autoantibodies
,
autoantigens
,
b-lymphocyte epitopes
,
crystal structure
Diabetes January 2007, Vol.56, 41-48. doi:https://doi.org/10.2337/db06-0237
Altered Natural Killer Cells in Type 1 Diabetic Patients
Melanie Rodacki; Britta Svoren; Vincent Butty; Whitney Besse; Lori Laffel; Christophe Benoist; Diane Mathis
Diabetes January 2007, Vol.56, 177-185. doi:https://doi.org/10.2337/db06-0493
Modulating Protective and Pathogenic CD4+ Subsets via CD137 in Type 1 Diabetes
Topics:
adoptive transfer
,
antibodies
,
antigens, cd25
,
cytokine
,
diabetes mellitus, type 1
Diabetes January 2007, Vol.56, 186-196. doi:https://doi.org/10.2337/db06-0793
Islet Studies
TIMP-1 Transgenic Mice Recover From Diabetes Induced by Multiple Low-Dose Streptozotocin
Hongwei Jiang; Hanyu Zhu; Xiangmei Chen; Youming Peng; Jianzhong Wang; Fuyou Liu; Suozhu Shi; Bo Fu; Yang Lu; Quan Hong; Zhe Feng; Kai Hou; Xuefeng Sun; Guangyan Cai; Xueguang Zhang; Yuansheng Xie
Topics:
insulin
,
mice
,
mice, transgenic
,
streptozocin
,
tissue-inhibitor of metalloproteinase-1
Diabetes January 2007, Vol.56, 49-56. doi:https://doi.org/10.2337/db06-0710
Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function
Topics:
mice
,
retinoblastoma protein
Diabetes January 2007, Vol.56, 57-64. doi:https://doi.org/10.2337/db06-0517
Human Islet Amyloid Polypeptide Oligomers Disrupt Cell Coupling, Induce Apoptosis, and Impair Insulin Secretion in Isolated Human Islets
Topics:
glucose
,
iapp gene
,
in situ nick-end labeling
,
insulin
,
insulin secretion
Diabetes January 2007, Vol.56, 65-71. doi:https://doi.org/10.2337/db06-0734
Induction of Indoleamine 2,3-Dioxygenase by Interferon-γ in Human Islets
Suparna A. Sarkar; Randall Wong; Seija I. Hackl; Ong Moua; Ronald G. Gill; Alexander Wiseman; Howard W. Davidson; John C. Hutton
Topics:
cytokine
,
interferons
,
polymerase chain reaction
,
rna, messenger
,
tryptophan oxygenase
Diabetes January 2007, Vol.56, 72-79. doi:https://doi.org/10.2337/db06-0617
Pro-Survival Role of Gelsolin in Mouse β-Cells
Topics:
apoptosis
,
gelsolin
,
mice
,
in situ nick-end labeling
,
caspase-3
Diabetes January 2007, Vol.56, 80-87. doi:https://doi.org/10.2337/db06-0769
Peroxisome Proliferator–Activated Receptor-γ Regulates Expression of PDX-1 and NKX6.1 in INS-1 Cells
Diabetes January 2007, Vol.56, 88-95. doi:https://doi.org/10.2337/db06-0948
FGFR3 Is a Negative Regulator of the Expansion of Pancreatic Epithelial Cells
Sandrine Arnaud-Dabernat; Marcie Kritzik; Ayse G. Kayali; You-Qing Zhang; Guoxun Liu; Cory Ungles; Nora Sarvetnick
Topics:
insulin
,
pancreas
,
signal transduction
,
fibroblast growth factor 9
,
epithelium
Diabetes January 2007, Vol.56, 96-106. doi:https://doi.org/10.2337/db05-1073
Vascular Reactivity in Arterioles From Normal and Alloxan-Diabetic Mice: Studies on Single Perfused Islets
Topics:
alloxan
,
angiotensin ii
,
arteriole
,
glucose
,
kidney glomerulus
Diabetes January 2007, Vol.56, 107-112. doi:https://doi.org/10.2337/db06-0623
Glucose-Stimulated Insulin Production in Mice Deficient for the PAS Kinase PASKIN
Emanuela Borter; Markus Niessen; Richard Zuellig; Giatgen A. Spinas; Patrick Spielmann; Gieri Camenisch; Roland H. Wenger
Topics:
glucose
,
insulin
,
mice
,
rna, messenger
,
phosphotransferases
Diabetes January 2007, Vol.56, 113-117. doi:https://doi.org/10.2337/db06-0798
The Role of Arachidonic Acid and Its Metabolites in Insulin Secretion From Human Islets of Langerhans
Shanta J. Persaud; Dany Muller; Véronique D. Belin; Isidora Kitsou-Mylona; Henry Asare-Anane; Alexandros Papadimitriou; Chris J. Burns; Guo Cai Huang; Stephanie A. Amiel; Peter M. Jones
Topics:
arachidonic acid
,
cobra perilaryngeal airway
,
endocrine pancreas
,
enzymes
,
glucose
Diabetes January 2007, Vol.56, 197-203. doi:https://doi.org/10.2337/db06-0490
Dominant-Negative α-Subunit of Farnesyl- and Geranyltransferase Inhibits Glucose-Stimulated, but Not KCl-Stimulated, Insulin Secretion in INS 832/13 Cells
Topics:
glucose
,
insulin secretion
,
potassium chloride
,
tissue membrane
,
gtp-binding proteins
Diabetes January 2007, Vol.56, 204-210. doi:https://doi.org/10.2337/db06-0668
Complications
Attenuation of Angiotensin II Signaling Recouples eNOS and Inhibits Nonendothelial NOX Activity in Diabetic Mice
Topics:
angiotensin ii
,
aorta
,
attenuation
,
candesartan cilexetil
,
captopril
Diabetes January 2007, Vol.56, 118-126. doi:https://doi.org/10.2337/db06-0288
Inhibition of Caspase-1/Interleukin-1β Signaling Prevents Degeneration of Retinal Capillaries in Diabetes and Galactosemia
Topics:
blood capillaries
,
caspase-1
,
caspases
,
interleukins
,
mice
Diabetes January 2007, Vol.56, 224-230. doi:https://doi.org/10.2337/db06-0427
Transforming Growth Factor-β2 and Connective Tissue Growth Factor in Proliferative Vitreoretinal Diseases: Possible Involvement of Hyalocytes and Therapeutic Potential of Rho Kinase Inhibitor
Takeshi Kita; Yasuaki Hata; Kumiko Kano; Muneki Miura; Shintaro Nakao; Yoshihiro Noda; Hiroaki Shimokawa; Tatsuro Ishibashi
Diabetes January 2007, Vol.56, 231-238. doi:https://doi.org/10.2337/db06-0581
Pharmacology and Therapeutics
Diabetes Abolishes Morphine-Induced Cardioprotection via Multiple Pathways Upstream of Glycogen Synthase Kinase-3β
Topics:
infarction
,
morphine
,
phosphotransferases
,
reperfusion therapy
,
physiologic reperfusion
Diabetes January 2007, Vol.56, 127-136. doi:https://doi.org/10.2337/db06-0907
Prevention and Treatment of Obesity, Insulin Resistance, and Diabetes by Bile Acid–Binding Resin
Misato Kobayashi; Hiroshi Ikegami; Tomomi Fujisawa; Koji Nojima; Yumiko Kawabata; Shinsuke Noso; Naru Babaya; Michiko Itoi-Babaya; Kaori Yamaji; Yoshihisa Hiromine; Masao Shibata; Toshio Ogihara
Topics:
bile-acid-binding resin
,
diet
,
insulin resistance
,
lipids
,
obesity
Diabetes January 2007, Vol.56, 239-247. doi:https://doi.org/10.2337/db06-0353
Combined Use of Rosiglitazone and Fenofibrate in Patients With Type 2 Diabetes: Prevention of Fluid Retention
Topics:
diabetes mellitus, type 2
,
fenofibrate
,
glucose
,
insulin
,
rosiglitazone
Diabetes January 2007, Vol.56, 248-255. doi:https://doi.org/10.2337/db06-0481
Brief Reports
Genotype-by-Sex Interaction on Fasting Insulin Concentration: The HyperGEN Study
Kari E. North; Nora Franceschini; Ingrid B. Borecki; C. Charles Gu; Gerardo Heiss; Michael A. Province; Donna K. Arnett; Cora E. Lewis; Michael B. Miller; Richard H. Myers; Steven C. Hunt; Barry I. Freedman
Topics:
fasting
,
genotype
,
hypertension
,
insulin
,
genetics
Diabetes January 2007, Vol.56, 137-142. doi:https://doi.org/10.2337/db06-0624
Common Genetic Variations in CCK, Leptin, and Leptin Receptor Genes Are Associated With Specific Human Eating Patterns
Mariken de Krom; Yvonne T. van der Schouw; Judith Hendriks; Roel A. Ophoff; Carla H. van Gils; Ronald P. Stolk; Diederick E. Grobbee; Roger Adan
Topics:
eating
,
genes
,
haplotypes
,
leptin
,
obesity
Diabetes January 2007, Vol.56, 276-280. doi:https://doi.org/10.2337/db06-0473
Metabolism
Exendin-4 Potently Decreases Ghrelin Levels in Fasting Rats
Diego Pérez-Tilve; Lucas González-Matías; Mayte Alvarez-Crespo; Roberto Leiras; Sulay Tovar; Carlos Diéguez; Federico Mallo
Topics:
fasting
,
ghrelin
,
glucagon-like peptide 1
,
peptides
,
rats
Diabetes January 2007, Vol.56, 143-151. doi:https://doi.org/10.2337/db05-0996
Signal Transduction
Role for Mitochondrial Reactive Oxygen Species in Brain Lipid Sensing: Redox Regulation of Food Intake
Alexandre Benani; Stéphanie Troy; Maria Carmen Carmona; Xavier Fioramonti; Anne Lorsignol; Corinne Leloup; Louis Casteilla; Luc Pénicaud
Topics:
brain
,
eating
,
hypertriglyceridemia
,
hypothalamus
,
intravenous fat emulsions
Diabetes January 2007, Vol.56, 152-160. doi:https://doi.org/10.2337/db06-0440
Pathophysiology
The Effect of Borderline Diabetes on the Risk of Dementia and Alzheimer’s Disease
Topics:
alzheimer's disease
,
dementia
,
follow-up
Diabetes January 2007, Vol.56, 211-216. doi:https://doi.org/10.2337/db06-0879
Antecedent Hindbrain Glucoprivation Does Not Impair the Counterregulatory Response to Hypoglycemia
Topics:
glucose
,
hindbrain
,
hypoglycemia
,
insulin
,
plasma glucose
Diabetes January 2007, Vol.56, 217-223. doi:https://doi.org/10.2337/db06-1025
Genetics
Screening of 134 Single Nucleotide Polymorphisms (SNPs) Previously Associated With Type 2 Diabetes Replicates Association With 12 SNPs in Nine Genes
Cristen J. Willer; Lori L. Bonnycastle; Karen N. Conneely; William L. Duren; Anne U. Jackson; Laura J. Scott; Narisu Narisu; Peter S. Chines; Andrew Skol; Heather M. Stringham; John Petrie; Michael R. Erdos; Amy J. Swift; Sareena T. Enloe; Andrew G. Sprau; Eboni Smith; Maurine Tong; Kimberly F. Doheny; Elizabeth W. Pugh; Richard M. Watanabe; Thomas A. Buchanan; Timo T. Valle; Richard N. Bergman; Jaakko Tuomilehto; Karen L. Mohlke; Francis S. Collins; Michael Boehnke
Diabetes January 2007, Vol.56, 256-264. doi:https://doi.org/10.2337/db06-0461
A Functional Polymorphism in the Manganese Superoxide Dismutase Gene and Diabetic Nephropathy
Anna Möllsten; Stefan L. Marklund; Maija Wessman; Maria Svensson; Carol Forsblom; Maikki Parkkonen; Kerstin Brismar; Per-Henrik Groop; Gisela Dahlquist
Topics:
diabetic nephropathy
,
manganese
,
polymorphism
,
smoking
,
superoxide dismutase
Diabetes January 2007, Vol.56, 265-269. doi:https://doi.org/10.2337/db06-0698
Genetic Control of Alternative Splicing in the TAP2 Gene: Possible Implication in the Genetics of Type 1 Diabetes
Hui-Qi Qu; Yang Lu; Luc Marchand; François Bacot; Rosalie Fréchette; Marie-Catherine Tessier; Alexandre Montpetit; Constantin Polychronakos
Topics:
diabetes mellitus, type 1
,
single nucleotide polymorphism
,
genetics
,
human leukocyte antigens
,
haplotypes
Diabetes January 2007, Vol.56, 270-275. doi:https://doi.org/10.2337/db06-0865
Commentary
β-Cell Regeneration: Epithelial Mesenchymal Transition Pre-EMTpted by Lineage Tracing?
Diabetes January 2007, Vol.56, 281-282. doi:https://doi.org/10.2337/db07-9901