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Volume 56, Issue 5
May 2007
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ISSN 0012-1797
EISSN 1939-327X
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Perspectives in Diabetes

The Heterogeneity of Diabetes: Unraveling a Dispute: Is Systemic Inflammation Related to Islet Autoimmunity?
Massimo Pietropaolo; Emma Barinas-Mitchell; Lewis H. Kuller
View articletitled, The Heterogeneity of Diabetes<span class="subtitle-colon">: </span><span class="subtitle">Unraveling a Dispute: Is Systemic Inflammation Related to Islet Autoimmunity?</span>
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Diabetes May 2007, Vol.56, 1189-1197. doi:https://doi.org/10.2337/db06-0880
Genetic Influences of Adiponectin on Insulin Resistance, Type 2 Diabetes, and Cardiovascular Disease
Claudia Menzaghi; Vincenzo Trischitta; Alessandro Doria
View articletitled, Genetic Influences of Adiponectin on Insulin Resistance, Type 2 Diabetes, and Cardiovascular Disease
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Diabetes May 2007, Vol.56, 1198-1209. doi:https://doi.org/10.2337/db06-0506

Signal Transduction

Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes
Hongmei Zhao; Malgorzata Przybylska; I-Huan Wu; Jinhua Zhang; Craig Siegel; Svetlana Komarnitsky; Nelson S. Yew; Seng H. Cheng
View articletitled, Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes
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Diabetes May 2007, Vol.56, 1210-1218. doi:https://doi.org/10.2337/db06-0719
Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells
Kenneth K.Y. Cheng; Karen S.L. Lam; Yu Wang; Yu Huang; David Carling; Donghai Wu; Chiwai Wong; Aimin Xu
View articletitled, Adiponectin-Induced Endothelial Nitric Oxide Synthase Activation and Nitric Oxide Production Are Mediated by APPL1 in Endothelial Cells
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Diabetes May 2007, Vol.56, 1387-1394. doi:https://doi.org/10.2337/db06-1580

Obesity Studies

Characterization of Glucosensing Neuron Subpopulations in the Arcuate Nucleus: Integration in Neuropeptide Y and Pro-Opio Melanocortin Networks?
Xavier Fioramonti; Sylvain Contié; Zhentao Song; Vanessa H. Routh; Anne Lorsignol; Luc Pénicaud
View articletitled, Characterization of Glucosensing Neuron Subpopulations in the Arcuate Nucleus<span class="subtitle-colon">: </span><span class="subtitle">Integration in Neuropeptide Y and Pro-Opio Melanocortin Networks?</span>
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Diabetes May 2007, Vol.56, 1219-1227. doi:https://doi.org/10.2337/db06-0567
Loss of Stearoyl-CoA Desaturase-1 Improves Insulin Sensitivity in Lean Mice but Worsens Diabetes in Leptin-Deficient Obese Mice
Jessica B. Flowers; Mary E. Rabaglia; Kathryn L. Schueler; Matthew T. Flowers; Hong Lan; Mark P. Keller; James M. Ntambi; Alan D. Attie
View articletitled, Loss of Stearoyl-CoA Desaturase-1 Improves Insulin Sensitivity in Lean Mice but Worsens Diabetes in Leptin-Deficient Obese Mice
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Diabetes May 2007, Vol.56, 1228-1239. doi:https://doi.org/10.2337/db06-1142

Immunology and Transplantation

Systemic Expression of Heme Oxygenase-1 Ameliorates Type 1 Diabetes in NOD Mice
Chien-Ming Hu; Heng-Huei Lin; Ming-Tsai Chiang; Pi-Fei Chang; Lee-Young Chau
View articletitled, Systemic Expression of Heme Oxygenase-1 Ameliorates Type 1 Diabetes in NOD Mice
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Diabetes May 2007, Vol.56, 1240-1247. doi:https://doi.org/10.2337/db06-0495
The Type and Frequency of Immunoregulatory CD4+ T-Cells Govern the Efficacy of Antigen-Specific Immunotherapy in Nonobese Diabetic Mice
Shannon M. Pop; Carmen P. Wong; Qiuming He; Yaming Wang; Mark A. Wallet; Kevin S. Goudy; Roland Tisch
View articletitled, The Type and Frequency of Immunoregulatory CD4<sup>+</sup> T-Cells Govern the Efficacy of Antigen-Specific Immunotherapy in Nonobese Diabetic Mice
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Diabetes May 2007, Vol.56, 1395-1402. doi:https://doi.org/10.2337/db06-0543

Islet Studies

Control of β-Cell Differentiation by the Pancreatic Mesenchyme
Myriam Attali; Volodymyr Stetsyuk; Annie Basmaciogullari; Virginie Aiello; Maria A. Zanta-Boussif; Bertrand Duvillie; Raphael Scharfmann
View articletitled, Control of β-Cell Differentiation by the Pancreatic Mesenchyme
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Diabetes May 2007, Vol.56, 1248-1258. doi:https://doi.org/10.2337/db06-1307
Cell-Permeable Pentapeptide V5 Inhibits Apoptosis and Enhances Insulin Secretion, Allowing Experimental Single-Donor Islet Transplantation in Mice
Jorge D. Rivas-Carrillo; Alejandro Soto-Gutierrez; Nalu Navarro-Alvarez; Hirofumi Noguchi; Teru Okitsu; Yong Chen; Takeshi Yuasa; Kimiaki Tanaka; Michiki Narushima; Atsushi Miki; Haruo Misawa; Yasuhiko Tabata; Hee-Sook Jun; Shinichi Matsumoto; Ira J. Fox; Noriaki Tanaka; Naoya Kobayashi
View articletitled, Cell-Permeable Pentapeptide V5 Inhibits Apoptosis and Enhances Insulin Secretion, Allowing Experimental Single-Donor Islet Transplantation in Mice
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Diabetes May 2007, Vol.56, 1259-1267. doi:https://doi.org/10.2337/db06-1679
Dominant-Negative Effects of a Novel Mutated Ins2 Allele Causes Early-Onset Diabetes and Severe β-Cell Loss in Munich Ins2C95S Mutant Mice
Nadja Herbach; Birgit Rathkolb; Elisabeth Kemter; Lisa Pichl; Matthias Klaften; Martin Hrabé de Angelis; Philippe A. Halban; Eckhard Wolf; Bernhard Aigner; Ruediger Wanke
View articletitled, Dominant-Negative Effects of a Novel Mutated <em>Ins2</em> Allele Causes Early-Onset Diabetes and Severe β-Cell Loss in Munich <em>Ins2</em><sup>C95S</sup> Mutant Mice
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Diabetes May 2007, Vol.56, 1268-1276. doi:https://doi.org/10.2337/db06-0658
Human Insulin Vesicle Dynamics During Pulsatile Secretion
Darren J. Michael; Wenyong Xiong; Xuehui Geng; Peter Drain; Robert H. Chow
View articletitled, Human Insulin Vesicle Dynamics During Pulsatile Secretion
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Diabetes May 2007, Vol.56, 1277-1288. doi:https://doi.org/10.2337/db06-0367
Caspase Inhibitor Therapy Enhances Marginal Mass Islet Graft Survival and Preserves Long-Term Function in Islet Transplantation
Juliet A. Emamaullee; Laura Stanton; Colleen Schur; A.M. James Shapiro
View articletitled, Caspase Inhibitor Therapy Enhances Marginal Mass Islet Graft Survival and Preserves Long-Term Function in Islet Transplantation
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Diabetes May 2007, Vol.56, 1289-1298. doi:https://doi.org/10.2337/db06-1653
Lineage Tracing Evidence for In Vitro Dedifferentiation but Rare Proliferation of Mouse Pancreatic β-Cells
Noa Weinberg; Limor Ouziel-Yahalom; Sarah Knoller; Shimon Efrat; Yuval Dor
View articletitled, Lineage Tracing Evidence for In Vitro Dedifferentiation but Rare Proliferation of Mouse Pancreatic β-Cells
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Diabetes May 2007, Vol.56, 1299-1304. doi:https://doi.org/10.2337/db06-1654
Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells
Simone Baltrusch; Sigurd Lenzen
View articletitled, Novel Insights Into the Regulation of the Bound and Diffusible Glucokinase in MIN6 β-Cells
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Diabetes May 2007, Vol.56, 1305-1315. doi:https://doi.org/10.2337/db06-0894
α1-Antitrypsin Protects β-Cells From Apoptosis
Bin Zhang; Yuanqing Lu; Martha Campbell-Thompson; Terry Spencer; Clive Wasserfall; Mark Atkinson; Sihong Song
View articletitled, α1-Antitrypsin Protects β-Cells From Apoptosis
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Diabetes May 2007, Vol.56, 1316-1323. doi:https://doi.org/10.2337/db06-1273
Toxic Human Islet Amyloid Polypeptide (h-IAPP) Oligomers Are Intracellular, and Vaccination to Induce Anti-Toxic Oligomer Antibodies Does Not Prevent h-IAPP–Induced β-Cell Apoptosis in h-IAPP Transgenic Mice
Chia-Yu Lin; Tatyana Gurlo; Rakez Kayed; Alexandra E. Butler; Leena Haataja; Charles G. Glabe; Peter C. Butler
View articletitled, Toxic Human Islet Amyloid Polypeptide (h-IAPP) Oligomers Are Intracellular, and Vaccination to Induce Anti-Toxic Oligomer Antibodies Does Not Prevent h-IAPP–Induced β-Cell Apoptosis in h-IAPP Transgenic Mice
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Diabetes May 2007, Vol.56, 1324-1332. doi:https://doi.org/10.2337/db06-1579

Complications

Glial Cell–Derived Cytokines Attenuate the Breakdown of Vascular Integrity in Diabetic Retinopathy
Nami Nishikiori; Makoto Osanai; Hideki Chiba; Takashi Kojima; Yoshinori Mitamura; Hiroshi Ohguro; Norimasa Sawada
View articletitled, Glial Cell–Derived Cytokines Attenuate the Breakdown of Vascular Integrity in Diabetic Retinopathy
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Diabetes May 2007, Vol.56, 1333-1340. doi:https://doi.org/10.2337/db06-1431
Effects of Insulin Replacements, Inhibitors of Angiotensin, and PKCβ's Actions to Normalize Cardiac Gene Expression and Fuel Metabolism in Diabetic Rats
Emi Arikawa; Ronald C.W. Ma; Keiji Isshiki; Ivan Luptak; Zhiheng He; Yutaka Yasuda; Yasuhiro Maeno; Mary Elizabeth Patti; Gordon C. Weir; Robert A. Harris; Victor A. Zammit; Rong Tian; George L. King
View articletitled, Effects of Insulin Replacements, Inhibitors of Angiotensin, and PKCβ's Actions to Normalize Cardiac Gene Expression and Fuel Metabolism in Diabetic Rats
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Diabetes May 2007, Vol.56, 1410-1420. doi:https://doi.org/10.2337/db06-0655
Functional Characteristics of Connective Tissue Growth Factor on Vitreoretinal Cells
Takeshi Kita; Yasuaki Hata; Muneki Miura; Shuhei Kawahara; Shintaro Nakao; Tatsuro Ishibashi
View articletitled, Functional Characteristics of Connective Tissue Growth Factor on Vitreoretinal Cells
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Diabetes May 2007, Vol.56, 1421-1428. doi:https://doi.org/10.2337/db06-1644
Glycoprotein Ibα Polymorphism T145M, Elevated Lipoprotein-Associated Phospholipase A2, and Hypertriglyceridemia Predict Risk for Recurrent Coronary Events in Diabetic Postinfarction Patients
James P. Corsetti; Dan Ryan; Arthur J. Moss; David L. Rainwater; Wojciech Zareba; Charles E. Sparks
View articletitled, Glycoprotein Ibα Polymorphism T145M, Elevated Lipoprotein-Associated Phospholipase A<sub>2</sub>, and Hypertriglyceridemia Predict Risk for Recurrent Coronary Events in Diabetic Postinfarction Patients
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Diabetes May 2007, Vol.56, 1429-1435. doi:https://doi.org/10.2337/db06-1573
Involvement of Heat Shock Factor-1 in Glycated LDL–Induced Upregulation of Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells
Ruozhi Zhao; Garry X. Shen
View articletitled, Involvement of Heat Shock Factor-1 in Glycated LDL–Induced Upregulation of Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells
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Diabetes May 2007, Vol.56, 1436-1444. doi:https://doi.org/10.2337/db06-1199
Activation of Sphingosine Kinase-1 Mediates Inhibition of Vascular Smooth Muscle Cell Apoptosis by Hyperglycemia
Bei You; Aixia Ren; Guijun Yan; Jianxin Sun
View articletitled, Activation of Sphingosine Kinase-1 Mediates Inhibition of Vascular Smooth Muscle Cell Apoptosis by Hyperglycemia
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Diabetes May 2007, Vol.56, 1445-1453. doi:https://doi.org/10.2337/db06-1418

Pharmacology and Therapeutics

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity
Johannes M. Aerts; Roelof Ottenhoff; Andrew S. Powlson; Aldo Grefhorst; Marco van Eijk; Peter F. Dubbelhuis; Jan Aten; Folkert Kuipers; Mireille J. Serlie; Tom Wennekes; Jaswinder K. Sethi; Stephen O'Rahilly; Hermen S. Overkleeft
View articletitled, Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity
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Diabetes May 2007, Vol.56, 1341-1349. doi:https://doi.org/10.2337/db06-1619

Genetics

Genetic Deletion of Trb3, the Mammalian Drosophila tribbles Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis
Haruka Okamoto; Esther Latres; Rong Liu; Karen Thabet; Andrew Murphy; David Valenzeula; George D. Yancopoulos; Trevor N. Stitt; David J. Glass; Mark W. Sleeman
View articletitled, Genetic Deletion of Trb3, the Mammalian <em>Drosophila tribbles</em> Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis
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Diabetes May 2007, Vol.56, 1350-1356. doi:https://doi.org/10.2337/db06-1448
Variants in ARHGEF11, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians
Lijun Ma; Robert L. Hanson; Lorem N. Que; Anna M.G. Cali; Mao Fu; Janel L. Mack; Aniello M. Infante; Sayuko Kobes; the International Type 2 Diabetes 1q Consortium; Clifton Bogardus; Alan R. Shuldiner; Leslie J. Baier
View articletitled, Variants in <em>ARHGEF11</em>, a Candidate Gene for the Linkage to Type 2 Diabetes on Chromosome 1q, Are Nominally Associated With Insulin Resistance and Type 2 Diabetes in Pima Indians
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Diabetes May 2007, Vol.56, 1454-1459. doi:https://doi.org/10.2337/db06-0640
Association Studies of BMI and Type 2 Diabetes in the Neuropeptide Y Pathway: A Possible Role for NPY2R as a Candidate Gene for Type 2 Diabetes in Men
Catarina D. Campbell; Helen N. Lyon; James Nemesh; Jared A. Drake; Tiinamaija Tuomi; Daniel Gaudet; Xiaofeng Zhu; Richard S. Cooper; Kristin G. Ardlie; Leif C. Groop; Joel N. Hirschhorn
View articletitled, Association Studies of BMI and Type 2 Diabetes in the Neuropeptide Y Pathway<span class="subtitle-colon">: </span><span class="subtitle">A Possible Role for <em>NPY2R</em> as a Candidate Gene for Type 2 Diabetes in Men</span>
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Diabetes May 2007, Vol.56, 1460-1467. doi:https://doi.org/10.2337/db06-1051
A Functional Variant of the Adipocyte Glycerol Channel Aquaporin 7 Gene Is Associated With Obesity and Related Metabolic Abnormalities
Sabrina Prudente; Elisabetta Flex; Eleonora Morini; Federica Turchi; Daria Capponi; Salvatore De Cosmo; Vittorio Tassi; Valentina Guida; Angelo Avogaro; Franco Folli; Francesca Maiani; Lucia Frittitta; Bruno Dallapiccola; Vincenzo Trischitta
View articletitled, A Functional Variant of the Adipocyte Glycerol Channel Aquaporin 7 Gene Is Associated With Obesity and Related Metabolic Abnormalities
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Diabetes May 2007, Vol.56, 1468-1474. doi:https://doi.org/10.2337/db06-1389

Brief Reports

A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM)
Ricard Masia; Diva D. De Leon; Courtney MacMullen; Heather McKnight; Charles A. Stanley; Colin G. Nichols
View articletitled, A Mutation in the TMD0-L0 Region of Sulfonylurea Receptor-1 (L225P) Causes Permanent Neonatal Diabetes Mellitus (PNDM)
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Diabetes May 2007, Vol.56, 1357-1362. doi:https://doi.org/10.2337/db06-1746
Evidence That Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) on 1q21 is a Type 2 Diabetes Susceptibility Gene in the Old Order Amish
Mao Fu; Mona M. Sabra; Coleen Damcott; Toni I. Pollin; Lijun Ma; Sandra Ott; John C. Shelton; Xiaolian Shi; Laurie Reinhart; Jeffrey O'Connell; Braxton D. Mitchell; Leslie J. Baier; Alan R. Shuldiner
View articletitled, Evidence That Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) on 1q21 is a Type 2 Diabetes Susceptibility Gene in the Old Order Amish
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Diabetes May 2007, Vol.56, 1363-1368. doi:https://doi.org/10.2337/db06-1421
Effects of Dipeptidyl Peptidase-4 Inhibition on Gastrointestinal Function, Meal Appearance, and Glucose Metabolism in Type 2 Diabetes
Adrian Vella; Gerlies Bock; Paula D. Giesler; Duane B. Burton; Denise B. Serra; Monica Ligueros Saylan; Beth E. Dunning; James E. Foley; Robert A. Rizza; Michael Camilleri
View articletitled, Effects of Dipeptidyl Peptidase-4 Inhibition on Gastrointestinal Function, Meal Appearance, and Glucose Metabolism in Type 2 Diabetes
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Diabetes May 2007, Vol.56, 1475-1480. doi:https://doi.org/10.2337/db07-0136
Transcription Factor 7-Like 2 (TCF7L2) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans
Richard M. Watanabe; Hooman Allayee; Anny H. Xiang; Enrique Trigo; Jaana Hartiala; Jean M. Lawrence; Thomas A. Buchanan
View articletitled, Transcription Factor 7-Like 2 (<em>TCF7L2</em>) Is Associated With Gestational Diabetes Mellitus and Interacts With Adiposity to Alter Insulin Secretion in Mexican Americans
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Diabetes May 2007, Vol.56, 1481-1485. doi:https://doi.org/10.2337/db06-1682

Metabolism

Direct Free Fatty Acid Uptake Into Human Adipocytes In Vivo: Relation to Body Fat Distribution
Samyah Shadid; Christina Koutsari; Michael D. Jensen
View articletitled, Direct Free Fatty Acid Uptake Into Human Adipocytes In Vivo<span class="subtitle-colon">: </span><span class="subtitle">Relation to Body Fat Distribution</span>
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Diabetes May 2007, Vol.56, 1369-1375. doi:https://doi.org/10.2337/db06-1680
Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients
Douglas E. Befroy; Kitt Falk Petersen; Sylvie Dufour; Graeme F. Mason; Robin A. de Graaf; Douglas L. Rothman; Gerald I. Shulman
View articletitled, Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients
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Diabetes May 2007, Vol.56, 1376-1381. doi:https://doi.org/10.2337/db06-0783
Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques
Daniel Kaufman; Mary Ann Banerji; Igor Shorman; Eric L.P. Smith; Jeremy D. Coplan; Leonard A. Rosenblum; John G. Kral
View articletitled, Early-Life Stress and the Development of Obesity and Insulin Resistance in Juvenile Bonnet Macaques
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Diabetes May 2007, Vol.56, 1382-1386. doi:https://doi.org/10.2337/db06-1409

Pathophysiology

Ca2+/Calmodulin-Dependent Protein Kinase Kinase-α Regulates Skeletal Muscle Glucose Uptake Independent of AMP-Activated Protein Kinase and Akt Activation
Carol A. Witczak; Nobuharu Fujii; Michael F. Hirshman; Laurie J. Goodyear
View articletitled, Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase Kinase-α Regulates Skeletal Muscle Glucose Uptake Independent of AMP-Activated Protein Kinase and Akt Activation
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Diabetes May 2007, Vol.56, 1403-1409. doi:https://doi.org/10.2337/db06-1230

Erratum

Errata
View articletitled, Errata
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Diabetes May 2007, Vol.56, 1486. doi:https://doi.org/10.2337/db07-er05

Online Letters to the Editor

Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255
Jeffrey S. Stroup
View articletitled, Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: <em>Diabetes</em> 56:248–255
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Diabetes May 2007, Vol.56, e1. doi:https://doi.org/10.2337/db07-0082
Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255
Guenther Boden
View articletitled, Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: <em>Diabetes</em> 56:248–255
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Diabetes May 2007, Vol.56, e2. doi:https://doi.org/10.2337/db07-0119
Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255
J. Karalliedde; G.C. Viberti
View articletitled, Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: <em>Diabetes</em> 56:248–255
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Diabetes May 2007, Vol.56, e3. doi:https://doi.org/10.2337/db07-0146
Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: Diabetes 56:248–255
Guenther Boden
View articletitled, Response to Comment on: Boden et al. (2007) Combined Use of Rosiglitazone and Fenofibrate in Patients with Type 2 Diabetes: Prevention of Fluid Retention: <em>Diabetes</em> 56:248–255
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Diabetes May 2007, Vol.56, e4. doi:https://doi.org/10.2337/db07-0216
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
300-OR: Beneficial Effect of the Combination Therapy of Cagrilintide, a Dual Amylin/Calcitonin Agonist, and Tirzepatide, a Dual GLP-1/GIP Agonist, on Body Weight Loss in Obese Rats
Elevated First-Trimester Neutrophil Count Is Closely Associated With the Development of Maternal Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes
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