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Issues
Editorials
2009 Presidential Address: Mentoring … Touching the Future
Topics:
mentors
,
touch sensation
,
mythology
Diabetes October 2009, Vol.58, 2165-2167. doi:https://doi.org/10.2337/db09-9029
Perspectives in Diabetes
Application of Isotopic Techniques Using Constant Specific Activity or Enrichment to the Study of Carbohydrate Metabolism
Topics:
glucose
Diabetes October 2009, Vol.58, 2168-2174. doi:https://doi.org/10.2337/db09-0318
Current Advances and Travails in Islet Transplantation
David M. Harlan; Norma Sue Kenyon; Olle Korsgren; Bart O. Roep; for the Immunology of Diabetes Society
Topics:
allografting
,
autoimmunity
,
diabetes mellitus, type 1
,
donors
,
insulin
Diabetes October 2009, Vol.58, 2175-2184. doi:https://doi.org/10.2337/db09-0476
Commentaries
Linking Fatty Acid Stress to β-Cell Mitochondrial Dynamics
Topics:
fatty acids
,
mitochondria
,
stress
Diabetes October 2009, Vol.58, 2185-2186. doi:https://doi.org/10.2337/db09-0967
Pretransplant Immune Parameters Associate With Islet Allograft Outcome: Implications for Transplant Strategy?
Topics:
allografting
,
transplantation
,
insulin
Diabetes October 2009, Vol.58, 2187-2188. doi:https://doi.org/10.2337/db09-1147
Original Article
Metabolism
Enhanced Hypothalamic Glucose Sensing in Obesity: Alteration of Redox Signaling
Anne-Laure Colombani; Lionel Carneiro; Alexandre Benani; Anne Galinier; Tristan Jaillard; Thibaut Duparc; Géraldine Offer; Anne Lorsignol; Christophe Magnan; Louis Casteilla; Luc Pénicaud; Corinne Leloup
Topics:
glucose
,
hypothalamus
,
mitochondria
,
obesity
,
rats
Diabetes July 2009, Vol.58, 2189-2197. doi:https://doi.org/10.2337/db09-0110
Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance
Erin E. Mulvihill; Emma M. Allister; Brian G. Sutherland; Dawn E. Telford; Cynthia G. Sawyez; Jane Y. Edwards; Janet M. Markle; Robert A. Hegele; Murray W. Huff
Topics:
diet
,
naringenin
,
triglycerides
,
mice
,
low density lipoprotein receptor
Diabetes July 2009, Vol.58, 2198-2210. doi:https://doi.org/10.2337/db09-0634
Gene Profiling of Human Adipose Tissue During Evoked Inflammation In Vivo
Rachana Shah; Yun Lu; Christine C. Hinkle; Fiona C. McGillicuddy; Roy Kim; Sridhar Hannenhalli; Thomas P. Cappola; Sean Heffron; XingMei Wang; Nehal N. Mehta; Mary Putt; Muredach P. Reilly
Topics:
adipocytes
,
adipose tissue
,
endotoxemia
,
genes
,
inflammation
Diabetes July 2009, Vol.58, 2211-2219. doi:https://doi.org/10.2337/db09-0256
Intramuscular Lipid Metabolism in the Insulin Resistance of Smoking
Bryan C. Bergman; Leigh Perreault; Devon M. Hunerdosse; Mary C. Koehler; Ali M. Samek; Robert H. Eckel
Topics:
glucose
,
insulin
,
insulin resistance
,
intramuscular injections
,
isotopes
Diabetes July 2009, Vol.58, 2220-2227. doi:https://doi.org/10.2337/db09-0481
Adipose Tissue Plasticity During Catch-Up Fat Driven by Thrifty Metabolism: Relevance for Muscle-Adipose Glucose Redistribution During Catch-Up Growth
Serge Summermatter; Helena Marcelino; Denis Arsenijevic; Antony Buchala; Olivier Aprikian; Françoise Assimacopoulos-Jeannet; Josiane Seydoux; Jean-Pierre Montani; Giovanni Solinas; Abdul G. Dulloo
Topics:
adipocytes
,
adipose tissue
,
fatty acids
,
glucose
,
insulin
Diabetes July 2009, Vol.58, 2228-2237. doi:https://doi.org/10.2337/db08-1793
Signal Transduction
Increased MAPK Activation and Impaired Insulin Signaling in Subcutaneous Microvascular Endothelial Cells in Type 2 Diabetes: The Role of Endothelin-1
Topics:
endothelial cells
,
endothelin-1
,
insulin
,
mitogen-activated protein kinases
,
m-vec protocol
Diabetes July 2009, Vol.58, 2238-2245. doi:https://doi.org/10.2337/db08-0961
Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid–Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin
Xiao-Nan Li; Jun Song; Lin Zhang; Scott A. LeMaire; Xiaoyang Hou; Cheng Zhang; Joseph S. Coselli; Li Chen; Xing Li Wang; Yun Zhang; Ying H. Shen
Topics:
aica ribonucleotide
,
ampk
,
forkhead box protein o3
,
palmitic acid
,
rna, small interfering
Diabetes July 2009, Vol.58, 2246-2257. doi:https://doi.org/10.2337/db08-1512
Obesity Studies
Glucagon-Like Peptide 1/Glucagon Receptor Dual Agonism Reverses Obesity in Mice
Alessandro Pocai; Paul E. Carrington; Jennifer R. Adams; Michael Wright; George Eiermann; Lan Zhu; Xiaobing Du; Aleksandr Petrov; Michael E. Lassman; Guoqiang Jiang; Franklin Liu; Corey Miller; Laurie M. Tota; Gaochao Zhou; Xiaoping Zhang; Michael M. Sountis; Alessia Santoprete; Elena Capito'; Gary G. Chicchi; Nancy Thornberry; Elisabetta Bianchi; Antonello Pessi; Donald J. Marsh; Ranabir SinhaRoy
Diabetes July 2009, Vol.58, 2258-2266. doi:https://doi.org/10.2337/db09-0278
Immunology and Transplantation
Differences in Baseline Lymphocyte Counts and Autoreactivity Are Associated With Differences in Outcome of Islet Cell Transplantation in Type 1 Diabetic Patients
Robert Hilbrands; Volkert A.L. Huurman; Pieter Gillard; Jurjen H.L. Velthuis; Marc De Waele; Chantal Mathieu; Leonard Kaufman; Miriam Pipeleers-Marichal; Zhidong Ling; Babak Movahedi; Daniel Jacobs-Tulleneers-Thevissen; Diethard Monbaliu; Dirk Ysebaert; Frans K. Gorus; Bart O. Roep; Daniel G. Pipeleers; Bart Keymeulen
Topics:
c-peptide
,
endocrine pancreas
,
insulin
,
islets of langerhans transplantation
,
lymphocyte count measurement
Diabetes July 2009, Vol.58, 2267-2276. doi:https://doi.org/10.2337/db09-0160
Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice
Matthew J. Parker; Song Xue; John J. Alexander; Clive H. Wasserfall; Martha L. Campbell-Thompson; Manuela Battaglia; Silvia Gregori; Clayton E. Mathews; Sihong Song; Misty Troutt; Scott Eisenbeis; John Williams; Desmond A. Schatz; Michael J. Haller; Mark A. Atkinson
Topics:
combined modality therapy
,
granulocyte colony-stimulating factor
,
mice
,
mice, inbred nod
,
diabetes mellitus, type 1
Diabetes July 2009, Vol.58, 2277-2284. doi:https://doi.org/10.2337/db09-0557
Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit: A Mechanism of Accelerated β-Cell Failure in Fulminant Type 1 Diabetes
Shoichiro Tanaka; Yoriko Nishida; Kaoru Aida; Taro Maruyama; Akira Shimada; Masako Suzuki; Hiroki Shimura; Soichi Takizawa; Masashi Takahashi; Daiichiro Akiyama; Sayaka Arai-Yamashita; Fumihiko Furuya; Akio Kawaguchi; Masahiro Kaneshige; Ryohei Katoh; Toyoshi Endo; Tetsuro Kobayashi
Topics:
cxc chemokines
,
diabetes mellitus, type 1
,
endocrine pancreas
,
enterovirus infections
,
interferons
Diabetes July 2009, Vol.58, 2285-2291. doi:https://doi.org/10.2337/db09-0091
Islet Studies
Importance of Extranuclear Estrogen Receptor-α and Membrane G Protein–Coupled Estrogen Receptor in Pancreatic Islet Survival
Suhuan Liu; Cedric Le May; Winifred P.S. Wong; Robert D. Ward; Deborah J. Clegg; Marco Marcelli; Kenneth S. Korach; Franck Mauvais-Jarvis
Topics:
apoptosis
,
estrogen
,
estrogen receptors
,
insulin
,
mice
Diabetes July 2009, Vol.58, 2292-2302. doi:https://doi.org/10.2337/db09-0257
Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis
Anthony J.A. Molina; Jakob D. Wikstrom; Linsey Stiles; Guy Las; Hibo Mohamed; Alvaro Elorza; Gil Walzer; Gilad Twig; Steve Katz; Barbara E. Corkey; Orian S. Shirihai
Topics:
mitochondria
,
glucose
Diabetes July 2009, Vol.58, 2303-2315. doi:https://doi.org/10.2337/db07-1781
Islet β-Cells Deficient in Bcl-xL Develop but Are Abnormally Sensitive to Apoptotic Stimuli
Emma M. Carrington; Mark D. McKenzie; Elisa Jansen; Michelle Myers; Stacey Fynch; Cameron Kos; Andreas Strasser; Thomas W. Kay; Clare L. Scott; Janette Allison
Topics:
bcl-xl protein
,
mice
Diabetes July 2009, Vol.58, 2316-2323. doi:https://doi.org/10.2337/db08-1602
Generation of Novel Single-Chain Antibodies by Phage-Display Technology to Direct Imaging Agents Highly Selective to Pancreatic β- or α-Cells In Vivo
Sandra Ueberberg; Juris J. Meier; Carmen Waengler; Wolfgang Schechinger; Johannes W. Dietrich; Andrea Tannapfel; Inge Schmitz; Ralf Schirrmacher; Manfred Köller; Harald H. Klein; Stephan Schneider
Topics:
bacteriophages
,
diagnostic imaging
,
insulin
,
libraries
,
pancreas
Diabetes July 2009, Vol.58, 2324-2334. doi:https://doi.org/10.2337/db09-0658
Complications
Functional Brain Connectivity and Neurocognitive Functioning in Patients With Long-Standing Type 1 Diabetes With and Without Microvascular Complications: A Magnetoencephalography Study
Eelco van Duinkerken; Martin Klein; Niki S.M. Schoonenboom; Roel P.L.M. Hoogma; Annette C. Moll; Frank J. Snoek; Cornelis J. Stam; Michaela Diamant
Topics:
brain
,
cognitive ability
,
diabetes mellitus, type 1
,
magnetoencephalography
,
neuropsychological tests
Diabetes July 2009, Vol.58, 2335-2343. doi:https://doi.org/10.2337/db09-0425
Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells
Jun Tanaka; Li Qiang; Alexander S. Banks; Carrie L. Welch; Michihiro Matsumoto; Tadahiro Kitamura; Yukari Ido-Kitamura; Ronald A. DePinho; Domenico Accili
Topics:
forkhead box protein o1
,
low-density lipoproteins
,
nitric oxide synthase
,
glucose
,
hyperglycemia
Diabetes July 2009, Vol.58, 2344-2354. doi:https://doi.org/10.2337/db09-0167
Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase–Mediated Cardiovascular Abnormalities in Streptozotocin-Induced Diabetic Rats
Prabhakara Reddy Nagareddy; Hesham Soliman; Guorong Lin; Padmesh S. Rajput; Ujendra Kumar; John H. McNeill; Kathleen M. MacLeod
Topics:
muscle, smooth, vascular
,
nitric oxide synthase
,
rats
,
glucose
,
heart
Diabetes July 2009, Vol.58, 2355-2364. doi:https://doi.org/10.2337/db09-0432
Vasohibin-1, a Negative Feedback Regulator of Angiogenesis, Ameliorates Renal Alterations in a Mouse Model of Diabetic Nephropathy
Tatsuyo Nasu; Yohei Maeshima; Masaru Kinomura; Kumiko Hirokoshi-Kawahara; Katsuyuki Tanabe; Hitoshi Sugiyama; Hikaru Sonoda; Yasufumi Sato; Hirofumi Makino
Topics:
cortex of kidney
,
diabetic nephropathy
,
kidney
,
kidney glomerulus
,
mice
Diabetes July 2009, Vol.58, 2365-2375. doi:https://doi.org/10.2337/db08-1790
Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1
Andrea M. Vincent; John M. Hayes; Lisa L. McLean; Anuradha Vivekanandan-Giri; Subramaniam Pennathur; Eva L. Feldman
Topics:
dyslipidemias
,
ganglia, spinal
,
glucose
,
mice
,
neurons
Diabetes July 2009, Vol.58, 2376-2385. doi:https://doi.org/10.2337/db09-0047
Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia
E. Shen; Yanwen Li; Ying Li; Limei Shan; Huaqing Zhu; Qingping Feng; J. Malcolm O. Arnold; Tianqing Peng
Topics:
apoptosis
,
cardiac myocytes
,
heart
,
hyperglycemia
,
hyperglycemic agents
Diabetes July 2009, Vol.58, 2386-2395. doi:https://doi.org/10.2337/db08-0617
TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SirT1
Marina Cardellini; Rossella Menghini; Eugenio Martelli; Viviana Casagrande; Arianna Marino; Stefano Rizza; Ottavia Porzio; Alessandro Mauriello; Anna Solini; Arnaldo Ippoliti; Renato Lauro; Franco Folli; Massimo Federici
Topics:
atheroma
,
diabetes mellitus, type 2
,
gelatinase b
,
atherosclerosis
,
loudness discomfort level
Diabetes July 2009, Vol.58, 2396-2401. doi:https://doi.org/10.2337/db09-0280
Genetics
Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue
Louise G. Grunnet; Emma Nilsson; Charlotte Ling; Torben Hansen; Oluf Pedersen; Leif Groop; Allan Vaag; Pernille Poulsen
Topics:
adipose tissue
,
fto gene
,
rna, messenger
,
skeletal muscles
,
twins
Diabetes July 2009, Vol.58, 2402-2408. doi:https://doi.org/10.2337/db09-0205
A Variant in the KCNQ1 Gene Predicts Future Type 2 Diabetes and Mediates Impaired Insulin Secretion
Anna Jonsson; Bo Isomaa; Tiinamaija Tuomi; Jalal Taneera; Albert Salehi; Peter Nilsson; Leif Groop; Valeriya Lyssenko
Topics:
diabetes mellitus, type 2
,
glucose
,
kvlqt1
,
insulin secretion
,
genes
Diabetes July 2009, Vol.58, 2409-2413. doi:https://doi.org/10.2337/db09-0246
Examination of Type 2 Diabetes Loci Implicates CDKAL1 as a Birth Weight Gene
Jianhua Zhao; Mingyao Li; Jonathan P. Bradfield; Kai Wang; Haitao Zhang; Patrick Sleiman; Cecilia E. Kim; Kiran Annaiah; Wendy Glaberson; Joseph T. Glessner; F. George Otieno; Kelly A. Thomas; Maria Garris; Cuiping Hou; Edward C. Frackelton; Rosetta M. Chiavacci; Robert I. Berkowitz; Hakon Hakonarson; Struan F.A. Grant
Topics:
birth weight
,
diabetes mellitus, type 2
Diabetes July 2009, Vol.58, 2414-2418. doi:https://doi.org/10.2337/db09-0506
Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel
Kevin S.C. Hamming; Daniel Soliman; Laura C. Matemisz; Omid Niazi; Yiqiao Lang; Anna L. Gloyn; Peter E. Light
Topics:
abcc8 gene
,
diabetes mellitus, type 2
,
genes
,
gliclazide
,
kcnj11 gene
Diabetes July 2009, Vol.58, 2419-2424. doi:https://doi.org/10.2337/db09-0143
Errata
Errata
Topics:
acronyms
,
afghanistan
,
atrial fibrillation
,
diabetes mellitus, type 1
,
pancreas
Diabetes October 2009, Vol.58, 2425. doi:https://doi.org/10.2337/db09-er10
Errata
Topics:
carboxy-lyases
,
diet, high-fat
,
glucose
,
insulin
,
malonyl coenzyme a
Diabetes October 2009, Vol.58, 2425. doi:https://doi.org/10.2337/db09-er10a
