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Banting Lecture
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Diabetes April 2009, Vol.58, 773-795. doi:https://doi.org/10.2337/db09-9028
Commentary
Commentaries
C-Reactive Protein and Prognosis in Diabetes: Getting to the Heart of the Matter
Diabetes April 2009, Vol.58, 798-799. doi:https://doi.org/10.2337/db08-1788
Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in β-Cell Function
Diabetes April 2009, Vol.58, 800-802. doi:https://doi.org/10.2337/db09-0099
Original Article
Metabolism
Sex and Depot Differences in Adipocyte Insulin Sensitivity and Glucose Metabolism
Diabetes January 2009, Vol.58, 803-812. doi:https://doi.org/10.2337/db08-1054
Relationship of Metabolic Syndrome With Incident Aortic Valve Calcium and Aortic Valve Calcium Progression: The Multi-Ethnic Study of Atherosclerosis (MESA)*
Ronit Katz; Matthew J. Budoff; Junichiro Takasu; David M. Shavelle; Alain Bertoni; Roger S. Blumenthal; Pamela Ouyang; Nathan D. Wong; Kevin D. O'Brien
Diabetes January 2009, Vol.58, 813-819. doi:https://doi.org/10.2337/db08-1515
β-Cell Hyperplasia Induced by Hepatic Insulin Resistance: Role of a Liver-Pancreas Endocrine Axis Through Insulin Receptor A Isoform
Oscar Escribano; Carlos Guillén; Carmen Nevado; Almudena Gómez-Hernández; C. Ronald Kahn; Manuel Benito
Diabetes January 2009, Vol.58, 820-828. doi:https://doi.org/10.2337/db08-0551
Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase–Dependent Pathway That Is Impaired With Obesity
Gregory R. Steinberg; Matthew J. Watt; Matthias Ernst; Morris J. Birnbaum; Bruce E. Kemp; Sebastian Beck Jørgensen
Diabetes January 2009, Vol.58, 829-839. doi:https://doi.org/10.2337/db08-0659
Mice With Hyperghrelinemia Are Hyperphagic and Glucose Intolerant and Have Reduced Leptin Sensitivity
Gavin A. Bewick; Aysha Kent; Daniel Campbell; Michael Patterson; Mohammed A. Ghatei; Stephen R. Bloom; James V. Gardiner
Diabetes January 2009, Vol.58, 840-846. doi:https://doi.org/10.2337/db08-1428
Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle
Håkan K.R. Karlsson; Alexander V. Chibalin; Heikki A. Koistinen; Jing Yang; Francoise Koumanov; Harriet Wallberg-Henriksson; Juleen R. Zierath; Geoffrey D. Holman
Diabetes February 2009, Vol.58, 847-854. doi:https://doi.org/10.2337/db08-1539
Obesity Studies
Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity
Maryam Ahmadian; Robin E. Duncan; Krista A. Varady; Danubia Frasson; Marc K. Hellerstein; Andreas L. Birkenfeld; Varman T. Samuel; Gerald I. Shulman; Yuhui Wang; Chulho Kang; Hei Sook Sul
Diabetes January 2009, Vol.58, 855-866. doi:https://doi.org/10.2337/db08-1644
BMI Changes During Childhood and Adolescence as Predictors of Amount of Adult Subcutaneous and Visceral Adipose Tissue in Men: The GOOD Study
Jenny M. Kindblom; Mattias Lorentzon; Åsa Hellqvist; Lars Lönn; John Brandberg; Staffan Nilsson; Ensio Norjavaara; Claes Ohlsson
Diabetes January 2009, Vol.58, 867-874. doi:https://doi.org/10.2337/db08-0606
Islet Studies
Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human β-Cell Replication and Function In Vivo
Nathalie Fiaschi-Taesch; Todd A. Bigatel; Brian Sicari; Karen K. Takane; Fatima Salim; Silvia Velazquez-Garcia; George Harb; Karen Selk; Irene Cozar-Castellano; Andrew F. Stewart
Diabetes January 2009, Vol.58, 882-893. doi:https://doi.org/10.2337/db08-0631
TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells
Gabriela da Silva Xavier; Merewyn K. Loder; Angela McDonald; Andrei I. Tarasov; Raffaella Carzaniga; Katrin Kronenberger; Sebastian Barg; Guy A. Rutter
Diabetes January 2009, Vol.58, 894-905. doi:https://doi.org/10.2337/db08-1187
Successful Versus Failed Adaptation to High-Fat Diet–Induced Insulin Resistance: The Role of IAPP-Induced β-Cell Endoplasmic Reticulum Stress
Diabetes January 2009, Vol.58, 906-916. doi:https://doi.org/10.2337/db08-1464
Complications
FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats
Diabetes January 2009, Vol.58, 917-925. doi:https://doi.org/10.2337/db08-0537
C-Reactive Protein and 5-Year Survival in Type 2 Diabetes: The Casale Monferrato Study
Graziella Bruno; Paolo Fornengo; Giulia Novelli; Francesco Panero; Massimo Perotto; Olivia Segre; Chiara Zucco; PierCarlo Deambrogio; Giuseppe Bargero; Paolo Cavallo Perin
Diabetes December 2008, Vol.58, 926-933. doi:https://doi.org/10.2337/db08-0900
Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy
George Francis; Jose Martinez; Wei Liu; Thuhien Nguyen; Amit Ayer; Jared Fine; Douglas Zochodne; Leah R. Hanson; William H. Frey, II; Cory Toth
Diabetes January 2009, Vol.58, 934-945. doi:https://doi.org/10.2337/db08-1287
Location of Arterial Stiffening Differs in Those With Impaired Fasting Glucose Versus Diabetes: Implications for Left Ventricular Hypertrophy From the Multi-Ethnic Study of Atherosclerosis
Pairoj Rerkpattanapipat; Ralph B. D'Agostino, Jr; Kerry M. Link; Eyal Shahar; Joao A. Lima; David A. Bluemke; Shantanu Sinha; David M. Herrington; W. Gregory Hundley
Diabetes January 2009, Vol.58, 946-953. doi:https://doi.org/10.2337/db08-1192
Protective Effect of Perindopril on Diabetic Retinopathy Is Associated With Decreased Vascular Endothelial Growth Factor–to–Pigment Epithelium–Derived Factor Ratio: Involvement of a Mitochondria–Reactive Oxygen Species Pathway
Zhi Zheng; Haibing Chen; Genjie Ke; Ying Fan; Haidong Zou; Xiaodong Sun; Qing Gu; Xun Xu; Patrick C.P. Ho
Diabetes February 2009, Vol.58, 954-964. doi:https://doi.org/10.2337/db07-1524
Pharmacology and Therapeutics
Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice
Jung Hwan Hwang; Dong Wook Kim; Eun Jin Jo; Yong Kyung Kim; Young Suk Jo; Ji Hoon Park; Sang Ku Yoo; Myung Kyu Park; Tae Hwan Kwak; Young Lim Kho; Jin Han; Hueng-Sik Choi; Sang-Hee Lee; Jin Man Kim; InKyu Lee; Taeyoon Kyung; Cholsoon Jang; Jongkyeong Chung; Gi Ryang Kweon; Minho Shong
Diabetes January 2009, Vol.58, 965-974. doi:https://doi.org/10.2337/db08-1183
GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice
Mohammad Hossein Noyan-Ashraf; M. Abdul Momen; Kiwon Ban; Al-Muktafi Sadi; Yu-Qing Zhou; Ali M. Riazi; Laurie L. Baggio; R. Mark Henkelman; Mansoor Husain; Daniel J. Drucker
Diabetes January 2009, Vol.58, 975-983. doi:https://doi.org/10.2337/db08-1193
Genetics
Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data
Helmut Laumen; Akuma D. Saningong; Iris M. Heid; Jochen Hess; Christian Herder; Melina Claussnitzer; Jens Baumert; Claudia Lamina; Wolfgang Rathmann; Eva-Maria Sedlmeier; Norman Klopp; Barbara Thorand; H.-Erich Wichmann; Thomas Illig; Hans Hauner
Diabetes December 2008, Vol.58, 984-991. doi:https://doi.org/10.2337/db07-1646
Breast-Feeding Modifies the Association of PPARγ2 Polymorphism Pro12Ala With Growth in Early Life: The Generation R Study
Dennis O. Mook-Kanamori; Eric A.P. Steegers; Andre G. Uitterlinden; Henriëtte A. Moll; Cornelia M. van Duijn; Albert Hofman; Vincent W.V. Jaddoe
Diabetes February 2009, Vol.58, 992-998. doi:https://doi.org/10.2337/db08-1311
Functional ENTPD1 Polymorphisms in African Americans With Diabetes and End-Stage Renal Disease
David J. Friedman; Matthew E. Talbert; Donald W. Bowden; Barry I. Freedman; Yves Mukanya; Keiichi Enjyoji; Simon C. Robson
Diabetes December 2008, Vol.58, 999-1006. doi:https://doi.org/10.2337/db08-1214
Type 1 Diabetes in the BB Rat: A Polygenic Disease
Robert H. Wallis; KeSheng Wang; Leili Marandi; Eugene Hsieh; Terri Ning; Gary Y.C. Chao; Janice Sarmiento; Andrew D. Paterson; Philippe Poussier
Diabetes January 2009, Vol.58, 1007-1017. doi:https://doi.org/10.2337/db08-1215
Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium
Patrick Concannon; Wei-Min Chen; Cécile Julier; Grant Morahan; Beena Akolkar; Henry A. Erlich; Joan E. Hilner; Jørn Nerup; Concepcion Nierras; Flemming Pociot; John A. Todd; Stephen S. Rich; the Type 1 Diabetes Genetics Consortium
Diabetes January 2009, Vol.58, 1018-1022. doi:https://doi.org/10.2337/db08-1551
Brief Report
Immunology and Transplantation
Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice
Andrea Valle; Tatiana Jofra; Angela Stabilini; Mark Atkinson; Maria-Grazia Roncarolo; Manuela Battaglia
Diabetes January 2009, Vol.58, 875-881. doi:https://doi.org/10.2337/db08-1432
Genetics
Do Non-HLA Genes Influence Development of Persistent Islet Autoimmunity and Type 1 Diabetes in Children With High-Risk HLA-DR,DQ Genotypes?
Andrea K. Steck; Weiming Zhang; Teodorica L. Bugawan; Katherine J. Barriga; Alan Blair; Henry A. Erlich; George S. Eisenbarth; Jill M. Norris; Marian J. Rewers
Diabetes February 2009, Vol.58, 1028-1033. doi:https://doi.org/10.2337/db08-1179
Brief Reports
Genetics
Common Variants of Hepatocyte Nuclear Factor 1β Are Associated With Type 2 Diabetes in a Chinese Population
Congrong Wang; Cheng Hu; Rong Zhang; Yuqian Bao; Xiaojing Ma; Jingyi Lu; Wen Qin; Xinyu Shao; Junxi Lu; Jing Xu; Huijuan Lu; Kunsan Xiang; Weiping Jia
Diabetes January 2009, Vol.58, 1023-1027. doi:https://doi.org/10.2337/db08-1064
