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Mortality and Glycemic Targets in the Intensive Care Unit: Another Paradigm Shift?
Topics:
intensive care unit
,
nice-sugar trial
,
insulin
,
glycemic control
Diabetes July 2009, Vol.58, 1469-1470. doi:https://doi.org/10.2337/db09-0540
Original Article
Perspectives in Diabetes
Abnormal Angiogenesis in Diabetic Nephropathy
Diabetes July 2009, Vol.58, 1471-1478. doi:https://doi.org/10.2337/db09-0119
Metabolism
Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys
Zhong Q. Wang; Z. Elizabeth Floyd; Jianhua Qin; Xiaotuan Liu; Yongmei Yu; Xian H. Zhang; Janice D. Wagner; William T. Cefalu
Topics:
1-phosphatidylinositol 3-kinase
,
insulin
,
irs1 protein, human
,
signal transduction
,
skeletal muscles
Diabetes March 2009, Vol.58, 1488-1498. doi:https://doi.org/10.2337/db08-0977
Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Expression
Jennifer L. Estall; Mario Kahn; Marcus P. Cooper; ffolliott Martin Fisher; Michele K. Wu; Dina Laznik; Lishu Qu; David E. Cohen; Gerald I. Shulman; Bruce M. Spiegelman
Topics:
insulin
,
liver
,
mice
,
signal transduction
,
triglycerides
Diabetes April 2009, Vol.58, 1499-1508. doi:https://doi.org/10.2337/db08-1571
Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
Zhanguo Gao; Jun Yin; Jin Zhang; Robert E. Ward; Roy J. Martin; Michael Lefevre; William T. Cefalu; Jianping Ye
Topics:
butyrates
,
mice
,
energy metabolism
,
obesity
,
diet, high-fat
Diabetes April 2009, Vol.58, 1509-1517. doi:https://doi.org/10.2337/db08-1637
Additive Interaction Between the Renin-Angiotensin System and Lipid Metabolism for Cancer in Type 2 Diabetes
Xilin Yang; Hailu Zhao; Yi Sui; Ronald C.W. Ma; Wing Yee So; Gary T.C. Ko; Alice P.S. Kong; Risa Ozaki; Chun Yip Yeung; Gang Xu; Peter C.Y. Tong; Juliana C.N. Chan
Topics:
angiotensin-converting enzyme inhibitors
,
cancer
,
diabetes mellitus, type 2
,
fat metabolism
,
insulin-like growth factor i
Diabetes April 2009, Vol.58, 1518-1525. doi:https://doi.org/10.2337/db09-0105
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity
Masayuki Saito; Yuko Okamatsu-Ogura; Mami Matsushita; Kumiko Watanabe; Takeshi Yoneshiro; Junko Nio-Kobayashi; Toshihiko Iwanaga; Masao Miyagawa; Toshimitsu Kameya; Kunihiro Nakada; Yuko Kawai; Masayuki Tsujisaki
Topics:
cold sensation
,
cold temperature
,
common cold
,
fluorodeoxyglucose f18
,
obesity
Diabetes April 2009, Vol.58, 1526-1531. doi:https://doi.org/10.2337/db09-0530
Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21
Knut Mai; Janin Andres; Katrin Biedasek; Jessica Weicht; Thomas Bobbert; Markus Sabath; Sabine Meinus; Franziska Reinecke; Matthias Möhlig; Martin O. Weickert; Markus Clemenz; Andreas F.H. Pfeiffer; Ulrich Kintscher; Simone Spuler; Joachim Spranger
Topics:
fatty acids
,
infusion procedures
,
insulin
,
lipids
,
nonesterified fatty acids
Diabetes April 2009, Vol.58, 1532-1538. doi:https://doi.org/10.2337/db08-1775
Additional Evidence That Transaldolase Exchange, Isotope Discrimination During the Triose-Isomerase Reaction, or Both Occur in Humans: Effects of Type 2 Diabetes
Rita Basu; Visvanthan Chandramouli; William Schumann; Ananda Basu; Bernard R. Landau; Robert A. Rizza
Topics:
deuterium
,
diabetes mellitus, type 2
,
glucose
,
isomerase
,
isotopes
Diabetes April 2009, Vol.58, 1539-1543. doi:https://doi.org/10.2337/db08-1300
Signal Transduction
Hypothalamic Reactive Oxygen Species Are Required for Insulin-Induced Food Intake Inhibition: An NADPH Oxidase–Dependent Mechanism
Tristan Jaillard; Michael Roger; Anne Galinier; Pascale Guillou; Alexandre Benani; Corinne Leloup; Louis Casteilla; Luc Pénicaud; Anne Lorsignol
Topics:
eating
,
hypothalamus
,
insulin
,
nadph oxidases
,
insulin administration
Diabetes April 2009, Vol.58, 1544-1549. doi:https://doi.org/10.2337/db08-1039
Obesity Studies
Impaired Preadipocyte Differentiation in Human Abdominal Obesity: Role of Wnt, Tumor Necrosis Factor-α, and Inflammation
Topics:
interleukin-6
,
obesity
,
tumor necrosis factors
,
resistin
,
macrophages
Diabetes April 2009, Vol.58, 1550-1557. doi:https://doi.org/10.2337/db08-1770
Macrophages and Adipocytes in Human Obesity: Adipose Tissue Gene Expression and Insulin Sensitivity During Calorie Restriction and Weight Stabilization
Frédéric Capel; Eva Klimčáková; Nathalie Viguerie; Balbine Roussel; Michaela Vítková; Michaela Kováčiková; Jan Polák; Zuzana Kováčová; Jean Galitzky; Jean-José Maoret; Jiří Hanáček; Tune H. Pers; Anne Bouloumié; Vladimir Štich; Dominique Langin
Topics:
adipocytes
,
adipose tissue
,
calorie restricted diet
,
diet
,
diet therapy
Diabetes April 2009, Vol.58, 1558-1567. doi:https://doi.org/10.2337/db09-0033
Immunology and Transplantation
CD4+CD25+ T-Cells Control Autoimmunity in the Absence of B-Cells
Eliana Mariño; Jeanette Villanueva; Stacey Walters; David Liuwantara; Fabienne Mackay; Shane T. Grey
Topics:
antigens, cd25
,
b-lymphocytes
,
mice
,
mice, inbred nod
,
t-lymphocytes
Diabetes March 2009, Vol.58, 1568-1577. doi:https://doi.org/10.2337/db08-1504
Majority of Children With Type 1 Diabetes Produce and Deposit Anti-Tissue Transglutaminase Antibodies in the Small Intestine
Mariantonia Maglio; Fiorella Florian; Monica Vecchiet; Renata Auricchio; Francesco Paparo; Raffaella Spadaro; Delia Zanzi; Luciano Rapacciuolo; Adriana Franzese; Daniele Sblattero; Roberto Marzari; Riccardo Troncone
Topics:
antibodies
,
immunoglobulin a
,
diabetes mellitus, type 1
,
celiac disease
,
biopsy
Diabetes April 2009, Vol.58, 1578-1584. doi:https://doi.org/10.2337/db08-0962
Pig Embryonic Pancreatic Tissue as a Source for Transplantation in Diabetes: Transient Treatment With Anti-LFA1, Anti-CD48, and FTY720 Enables Long-Term Graft Maintenance in Mice With Only Mild Ongoing Immunosuppression
Dalit Tchorsh-Yutsis; Gil Hecht; Anna Aronovich; Elias Shezen; Yael Klionsky; Chava Rosen; Rivka Bitcover; Smadar Eventov-Friedman; Helena Katchman; Sivan Cohen; Orna Tal; Oren Milstein; Hideo Yagita; Bruce R. Blazar; Yair Reisner
Topics:
cd48 antigen
,
embryo
,
fingolimod
,
insulin
,
lymphocyte function-associated antigen-1
Diabetes April 2009, Vol.58, 1585-1594. doi:https://doi.org/10.2337/db09-0112
Islet Studies
Functional Assessment of Pancreatic β-Cell Area in Humans
Juris J. Meier; Bjoern A. Menge; Thomas G.K. Breuer; Christophe A. Müller; Andrea Tannapfel; Waldemar Uhl; Wolfgang E. Schmidt; Henning Schrader
Topics:
c-peptide
,
glucose
,
insulin
,
pancreas
,
glycemic control
Diabetes July 2009, Vol.58, 1595-1603. doi:https://doi.org/10.2337/db08-1611
Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes: Interactions With Metformin
Aleksey V. Matveyenko; Sarah Dry; Heather I. Cox; Artemis Moshtaghian; Tatyana Gurlo; Ryan Galasso; Alexandra E. Butler; Peter C. Butler
Topics:
hip joint
,
hip region
,
metformin
,
rats
,
sitagliptin
Diabetes April 2009, Vol.58, 1604-1615. doi:https://doi.org/10.2337/db09-0058
Inhibitory Effects of Leptin on Pancreatic α-Cell Function
Eva Tudurí; Laura Marroquí; Sergi Soriano; Ana B. Ropero; Thiago M. Batista; Sandra Piquer; Miguel A. López-Boado; Everardo M. Carneiro; Ramón Gomis; Angel Nadal; Ivan Quesada
Topics:
leptin
,
glucose
,
signal transduction
Diabetes April 2009, Vol.58, 1616-1624. doi:https://doi.org/10.2337/db08-1787
Complications
(Pro)renin Receptor–Mediated Signal Transduction and Tissue Renin-Angiotensin System Contribute to Diabetes-Induced Retinal Inflammation
Shingo Satofuka; Atsuhiro Ichihara; Norihiro Nagai; Kousuke Noda; Yoko Ozawa; Akiyoshi Fukamizu; Kazuo Tsubota; Hiroshi Itoh; Yuichi Oike; Susumu Ishida
Topics:
renin
,
signal transduction
,
vascular endothelial growth factor a
,
intercellular adhesion molecule 1
,
retina
Diabetes April 2009, Vol.58, 1625-1633. doi:https://doi.org/10.2337/db08-0254
Elevated Triglycerides Correlate With Progression of Diabetic Neuropathy
Timothy D. Wiggin; Kelli A. Sullivan; Rodica Pop-Busui; Antonino Amato; Anders A.F. Sima; Eva L. Feldman
Topics:
diabetic neuropathies
,
hypertriglyceridemia
,
sural nerve
,
triglycerides
,
secondary data analysis
Diabetes May 2009, Vol.58, 1634-1640. doi:https://doi.org/10.2337/db08-1771
Allelic Depletion of grem1 Attenuates Diabetic Kidney Disease
Sarah A. Roxburgh; Jayesh J. Kattla; Simon P. Curran; Yvonne M. O'Meara; Carol A. Pollock; Roel Goldschmeding; Catherine Godson; Finian Martin; Derek P. Brazil
Topics:
diabetic nephropathy
,
grem1 gene
,
kidney
,
mice
,
diabetes mellitus, type 1
Diabetes April 2009, Vol.58, 1641-1650. doi:https://doi.org/10.2337/db08-1365
The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes
Per-Henrik Groop; Merlin C. Thomas; John L. Moran; Johan Wadèn; Lena M. Thorn; Ville-Petteri Mäkinen; Milla Rosengård-Bärlund; Markku Saraheimo; Kustaa Hietala; Outi Heikkilä; Carol Forsblom; on behalf of the FinnDiane Study Group
Diabetes April 2009, Vol.58, 1651-1658. doi:https://doi.org/10.2337/db08-1543
The Transforming Growth Factor-β Pathway Is a Common Target of Drugs That Prevent Experimental Diabetic Retinopathy
Topics:
aspirin
,
rats
,
retinal vessels
,
diabetic retinopathy
,
inflammation
Diabetes April 2009, Vol.58, 1659-1667. doi:https://doi.org/10.2337/db08-1008
Serum Uric Acid as a Predictor for Development of Diabetic Nephropathy in Type 1 Diabetes: An Inception Cohort Study
Topics:
diabetes mellitus, type 1
,
diabetic nephropathy
,
kidney diseases
,
microalbuminuria
,
microbiology procedures
Diabetes May 2009, Vol.58, 1668-1671. doi:https://doi.org/10.2337/db09-0014
Genetics
Lack of Type VIII Collagen in Mice Ameliorates Diabetic Nephropathy
Ulrike Hopfer; Helmut Hopfer; Catherine Meyer-Schwesinger; Ivonne Loeffler; Naomi Fukai; Bjorn R. Olsen; Rolf A.K. Stahl; Gunter Wolf
Topics:
collagen type viii
,
diabetic nephropathy
,
glucose
,
mice
,
platelet-derived growth factor
Diabetes April 2009, Vol.58, 1672-1681. doi:https://doi.org/10.2337/db08-0183
Common Variation in SIM1 Is Reproducibly Associated With BMI in Pi ma Indians
Michael Traurig; Janel Mack; Robert L. Hanson; Maya Ghoussaini; David Meyre; William C. Knowler; Sayuko Kobes; Philippe Froguel; Clifton Bogardus; Leslie J. Baier
Topics:
body mass index procedure
,
genotype determination
,
obesity
,
alleles
,
introns
Diabetes April 2009, Vol.58, 1682-1689. doi:https://doi.org/10.2337/db09-0028
Confirmation of Multiple Risk Loci and Genetic Impacts by a Genome-Wide Association Study of Type 2 Diabetes in the Japanese Population
Fumihiko Takeuchi; Masakuni Serizawa; Ken Yamamoto; Tomomi Fujisawa; Eitaro Nakashima; Keizo Ohnaka; Hiroshi Ikegami; Takao Sugiyama; Tomohiro Katsuya; Makoto Miyagishi; Naoki Nakashima; Hajime Nawata; Jiro Nakamura; Suminori Kono; Ryoichi Takayanagi; Norihiro Kato
Topics:
diabetes mellitus, type 2
,
single nucleotide polymorphism
,
genome-wide association study
,
genotype determination
,
genotype
Diabetes April 2009, Vol.58, 1690-1699. doi:https://doi.org/10.2337/db08-1494
NOD × 129.H2g7 Backcross Delineates 129S1/SvImJ-Derived Genomic Regions Modulating Type 1 Diabetes Development in Mice
Topics:
diabetes mellitus, type 1
,
genome
,
mice
,
quantitative trait loci
Diabetes March 2009, Vol.58, 1700-1703. doi:https://doi.org/10.2337/db09-0120
Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q
Inga Prokopenko; Eleftheria Zeggini; Robert L. Hanson; Braxton D. Mitchell; N. William Rayner; Pelin Akan; Leslie Baier; Swapan K. Das; Katherine S. Elliott; Mao Fu; Timothy M. Frayling; Christopher J. Groves; Rhian Gwilliam; Laura J. Scott; Benjamin F. Voight; Andrew T. Hattersley; Cheng Hu; Andrew D. Morris; Maggie Ng; Colin N.A. Palmer; Marcela Tello-Ruiz; Martine Vaxillaire; Cong-rong Wang; Lincoln Stein; Juliana Chan; Weiping Jia; Philippe Froguel; Steven C. Elbein; Panos Deloukas; Clifton Bogardus; Alan R. Shuldiner; Mark I. McCarthy; for the International Type 2 Diabetes 1q Consortium
Topics:
diabetes mellitus, type 2
,
linkage disequilibrium
,
single nucleotide polymorphism
,
genome
,
chromosome 1q
Diabetes April 2009, Vol.58, 1704-1709. doi:https://doi.org/10.2337/db09-0081
Elevated MBL Concentrations Are Not an Indication of Association Between the MBL2 Gene and Type 1 Diabetes or Diabetic Nephropathy
Mari A. Kaunisto; Lisa Sjölind; Riitta Sallinen; Kim Pettersson-Fernholm; Markku Saraheimo; Sara Fröjdö; Carol Forsblom; Johan Fagerudd; Troels K. Hansen; Allan Flyvbjerg; Maija Wessman; Per-Henrik Groop; for the FinnDiane Study Group
Topics:
diabetes mellitus, type 1
,
diabetic nephropathy
,
kidney diseases
,
single nucleotide polymorphism
,
genotype determination
Diabetes April 2009, Vol.58, 1710-1714. doi:https://doi.org/10.2337/db08-1495
Association of Type 2 Diabetes Candidate Polymorphisms in KCNQ1 With Incretin and Insulin Secretion
Karsten Müssig; Harald Staiger; Fausto Machicao; Kerstin Kirchhoff; Martina Guthoff; Silke A. Schäfer; Konstantinos Kantartzis; Günther Silbernagel; Norbert Stefan; Jens J. Holst; Baptist Gallwitz; Hans-Ulrich Häring; Andreas Fritsche
Topics:
diabetes mellitus, type 2
,
incretin
,
insulin secretion
,
kvlqt1
,
oral glucose tolerance test
Diabetes April 2009, Vol.58, 1715-1720. doi:https://doi.org/10.2337/db08-1589
Commentary
Commentaries
Targeting B-cells Mitigates Autoimmune Diabetes in NOD Mice: What Is Plan B?
Topics:
autoimmunity
,
b-lymphocytes
,
contraception, postcoital
,
levonorgestrel
,
mice, inbred nod
Diabetes July 2009, Vol.58, 1479-1481. doi:https://doi.org/10.2337/db09-0497
Brown Fat in Humans: Turning up the Heat on Obesity
Topics:
brown fat
,
heat (physical force)
,
obesity
Diabetes July 2009, Vol.58, 1482-1484. doi:https://doi.org/10.2337/db09-0622
(Pro)renin Receptor: A Treatment Target for Diabetic Retinopathy?
Topics:
diabetic retinopathy
,
renin
,
angiotensin ii
Diabetes July 2009, Vol.58, 1485-1487. doi:https://doi.org/10.2337/db09-0604
Erratum
Errata
Topics:
glucose
,
glucose tolerance
,
insulin secretion
,
mice
,
pancreas
Diabetes July 2009, Vol.58, 1721. doi:https://doi.org/10.2337/db09-er07
