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Commentaries

The Hypothalamus and β-Cell Connection in the Gene-Targeting Era

Michael W. Schwartz; Stephan J. Guyenet; Vincenzo Cirulli

Abstracts

View articletitled, The Hypothalamus and β-Cell Connection in the Gene-Targeting Era

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Topics: gene targeting , hypothalamus , mice , genes , pancreas

Diabetes December 2010, Vol.59, 2991-2993. doi:https://doi.org/10.2337/db10-1149

ACE2 and Diabetes: ACE of ACEs?

Daniel Batlle; Maria Jose Soler; Minghao Ye

Abstracts

View articletitled, ACE2 and Diabetes: ACE of ACEs?

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Topics: angiotensin ii , angiotensins , endocrine pancreas , gene therapy , insulin secretion

Diabetes December 2010, Vol.59, 2994-2996. doi:https://doi.org/10.2337/db10-1205

Mortality Risk in Long-Standing Type 1 Diabetes: Hope and Concern

Richard F. Hamman

Abstracts

View articletitled, Mortality Risk in Long-Standing Type 1 Diabetes: Hope and Concern

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Topics: diabetes mellitus, type 1 , cardiovascular diseases

Diabetes December 2010, Vol.59, 2997-2998. doi:https://doi.org/10.2337/db10-1213

Metabolism

A Soluble Guanylate Cyclase–Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo

Zhibo An; Jason J. Winnick; Ben Farmer; Doss Neal; Margaret Lautz; Jose M. Irimia; Peter J. Roach; Alan D. Cherrington

Abstracts

View articletitled, A Soluble Guanylate Cyclase–Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo

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Topics: cyclic gmp , glucose , glucose uptake , infusion procedures , liver

Diabetes September 2010, Vol.59, 2999-3007. doi:https://doi.org/10.2337/db10-0138

Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue–Derived Microvascular Endothelial Cells

Samantha L. Hocking; Lindsay E. Wu; Michael Guilhaus; Donald J. Chisholm; David E. James

Abstracts

View articletitled, Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue–Derived Microvascular Endothelial Cells

Supplementary data

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Topics: adipose tissue , culture media , endothelial cells , isotopes , mass spectrometry

Diabetes September 2010, Vol.59, 3008-3016. doi:https://doi.org/10.2337/db10-0483

First-Trimester Prediction of Gestational Diabetes Mellitus: Examining the Potential of Combining Maternal Characteristics and Laboratory Measures

Makrina Savvidou; Scott M. Nelson; Mahlatse Makgoba; Claudia-Martina Messow; Naveed Sattar; Kypros Nicolaides

Abstracts

View articletitled, First-Trimester Prediction of Gestational Diabetes Mellitus: Examining the Potential of Combining Maternal Characteristics and Laboratory Measures

Supplementary data

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Topics: adiponectin , alteplase , body mass index procedure , c-reactive protein , diabetes mellitus, type 2

Diabetes September 2010, Vol.59, 3017-3022. doi:https://doi.org/10.2337/db10-0688

Metformin Treatment May Increase Omentin-1 Levels in Women With Polycystic Ovary Syndrome

Bee K. Tan; Raghu Adya; Syed Farhatullah; Jing Chen; Hendrik Lehnert; Harpal S. Randeva

Abstracts

View articletitled, Metformin Treatment May Increase Omentin-1 Levels in Women With Polycystic Ovary Syndrome

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Topics: c-reactive protein , metformin , polycystic ovary syndrome , proto-oncogene proteins c-akt , endothelial cells

Diabetes September 2010, Vol.59, 3023-3031. doi:https://doi.org/10.2337/db10-0124

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance

Frank K. Huynh; Jasna Levi; Heather C. Denroche; Sarah L. Gray; Peter J. Voshol; Ursula H. Neumann; Madeleine Speck; Streamson C. Chua; Scott D. Covey; Timothy J. Kieffer

Abstracts

View articletitled, Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance

Supplementary data

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Topics: insulin , leptin , mice , signal transduction , glucose

Diabetes September 2010, Vol.59, 3032-3040. doi:https://doi.org/10.2337/db10-0074

Regulation of Fasting Fuel Metabolism by Toll-Like Receptor 4

Shanshan Pang; Haiqing Tang; Shu Zhuo; Ying Qin Zang; Yingying Le

Abstracts

View articletitled, Regulation of Fasting Fuel Metabolism by Toll-Like Receptor 4

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Topics: fasting , toll-like receptor 4 , mice , skeletal muscles

Diabetes September 2010, Vol.59, 3041-3048. doi:https://doi.org/10.2337/db10-0418

Obesity Studies

Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers

Jean-Pierre Furet; Ling-Chun Kong; Julien Tap; Christine Poitou; Arnaud Basdevant; Jean-Luc Bouillot; Denis Mariat; Gérard Corthier; Joël Doré; Corneliu Henegar; Salwa Rizkalla; Karine Clément

Abstracts

View articletitled, Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers

Supplementary data

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Topics: bacteroides , inflammatory markers , microbiome , obesity , prevotella

Diabetes September 2010, Vol.59, 3049-3057. doi:https://doi.org/10.2337/db10-0253

Maternal Antioxidant Supplementation Prevents Adiposity in the Offspring of Western Diet–Fed Rats

Sarbattama Sen; Rebecca A. Simmons

Abstracts

View articletitled, Maternal Antioxidant Supplementation Prevents Adiposity in the Offspring of Western Diet–Fed Rats

Supplementary data

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Topics: antioxidants , diet , diet, western , obesity , pregnancy

Diabetes September 2010, Vol.59, 3058-3065. doi:https://doi.org/10.2337/db10-0301

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice

Phillip J. White; Makoto Arita; Ryo Taguchi; Jing X. Kang; André Marette

Abstracts

View articletitled, Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice

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Topics: animals, transgenic , heart failure , inflammation , insulin , insulin resistance

Diabetes September 2010, Vol.59, 3066-3073. doi:https://doi.org/10.2337/db10-0054

Combined Neural Inactivation of Suppressor of Cytokine Signaling-3 and Protein-Tyrosine Phosphatase-1B Reveals Additive, Synergistic, and Factor-Specific Roles in the Regulation of Body Energy Balance

Nadege Briancon; David E. McNay; Eleftheria Maratos-Flier; Jeffrey S. Flier

Abstracts

View articletitled, Combined Neural Inactivation of Suppressor of Cytokine Signaling-3 and Protein-Tyrosine Phosphatase-1B Reveals Additive, Synergistic, and Factor-Specific Roles in the Regulation of Body Energy Balance

Supplementary data

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Topics: leptin , mice , nestin protein , suppressor of cytokine signaling 3 protein , diet

Diabetes September 2010, Vol.59, 3074-3084. doi:https://doi.org/10.2337/db10-0481

Associations of Six Single Nucleotide Polymorphisms in Obesity-Related Genes With BMI and Risk of Obesity in Chinese Children

Lijun Wu; Bo Xi; Meixian Zhang; Yue Shen; Xiaoyuan Zhao; Hong Cheng; Dongqing Hou; Dandan Sun; Jurg Ott; Xingyu Wang; Jie Mi

Abstracts

View articletitled, Associations of Six Single Nucleotide Polymorphisms in Obesity-Related Genes With BMI and Risk of Obesity in Chinese Children

Supplementary data

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Topics: body mass index procedure , child , obesity , single nucleotide polymorphism , genes

Diabetes September 2010, Vol.59, 3085-3089. doi:https://doi.org/10.2337/db10-0273

Islet Studies

Conditional Gene Targeting in Mouse Pancreatic β-Cells: Analysis of Ectopic Cre Transgene Expression in the Brain

Barton Wicksteed; Marcela Brissova; Wenbo Yan; Darren M. Opland; Jennifer L. Plank; Rachel B. Reinert; Lorna M. Dickson; Natalia A. Tamarina; Louis H. Philipson; Alena Shostak; Ernesto Bernal-Mizrachi; Lynda Elghazi; Michael W. Roe; Patricia A. Labosky; Martin G. Myers, Jr.; Maureen Gannon; Alvin C. Powers; Peter J. Dempsey

Abstracts

View articletitled, Conditional Gene Targeting in Mouse Pancreatic β-Cells: Analysis of Ectopic Cre Transgene Expression in the Brain

Supplementary data

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Topics: brain , mice , pancreas , leptin , animals, transgenic

Diabetes August 2010, Vol.59, 3090-3098. doi:https://doi.org/10.2337/db10-0624

Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

Kyle W. Sloop; Francis S. Willard; Martin B. Brenner; James Ficorilli; Kathleen Valasek; Aaron D. Showalter; Thomas B. Farb; Julia X.C. Cao; Amy L. Cox; M. Dodson Michael; Sonia Maria Gutierrez Sanfeliciano; Mark J. Tebbe; Michael J. Coghlan

Abstracts

View articletitled, Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets

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Topics: corticosterone , glucagon-like peptide 1 , glucagon-like peptide-1 agonists , glucagon-like peptide-1 receptor , glucose

Diabetes September 2010, Vol.59, 3099-3107. doi:https://doi.org/10.2337/db10-0689

In Vivo Expression of HGF/NK1 and GLP-1 From dsAAV Vectors Enhances Pancreatic β-Cell Proliferation and Improves Pathology in the db/db Mouse Model of Diabetes

Daniel F. Gaddy; Michael J. Riedel; Sharmila Pejawar-Gaddy; Timothy J. Kieffer; Paul D. Robbins

Abstracts

View articletitled, In Vivo Expression of HGF/NK1 and GLP-1 From dsAAV Vectors Enhances Pancreatic β-Cell Proliferation and Improves Pathology in the db/db Mouse Model of Diabetes

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Topics: glucagon-like peptide 1 , mice , spatial vectors

Diabetes September 2010, Vol.59, 3108-3116. doi:https://doi.org/10.2337/db09-1886

Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes

Linyuan Wang; Yunfeng Liu; Shun Yan Lu; Kinh-Tung T. Nguyen; Stephanie A. Schroer; Akira Suzuki; Tak W. Mak; Herbert Gaisano; Minna Woo

Abstracts

View articletitled, Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes

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Topics: mice , pten gene , signal transduction , diabetes mellitus, type 2 , phosphoinositide 3-kinase

Diabetes September 2010, Vol.59, 3117-3126. doi:https://doi.org/10.2337/db09-1805

Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

Michael I. Goran; Ryan Walker; Kim-Anne Le; Swapna Mahurkar; Susanna Vikman; Jaimie N. Davis; Donna Spruijt-Metz; Marc J. Weigensberg; Hooman Allayee

Abstracts

View articletitled, Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

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Topics: adolescent , child , liver , pnpla3 gene , obesity

Diabetes September 2010, Vol.59, 3127-3130. doi:https://doi.org/10.2337/db10-0554

Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Nagesha Guthalu Kondegowda; Sheela Joshi-Gokhale; George Harb; Katoura Williams; Xiao Ying Zhang; Karen K. Takane; Pili Zhang; Donald K. Scott; Andrew F. Stewart; Adolfo Garcia-Ocaña; Rupangi C. Vasavada

Abstracts

View articletitled, Parathyroid Hormone–Related Protein Enhances Human β-Cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Supplementary data

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Topics: cdk2 protein, human , cyclin e , parathyroid hormone-related protein

Diabetes September 2010, Vol.59, 3131-3138. doi:https://doi.org/10.2337/db09-1796

Immunology and Transplantation

Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes

Mollie Jurewicz; Sunmi Yang; Andrea Augello; Jonathan G. Godwin; Robert F. Moore; Jamil Azzi; Paolo Fiorina; Mark Atkinson; Mohamed H. Sayegh; Reza Abdi

Abstracts

View articletitled, Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes

Supplementary data

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Topics: cytokine , diabetes mellitus, type 1 , hyperglycemia , interleukin-6 , mice

Diabetes September 2010, Vol.59, 3139-3147. doi:https://doi.org/10.2337/db10-0542

Virtual Optimization of Nasal Insulin Therapy Predicts Immunization Frequency to Be Crucial for Diabetes Protection

Georgia Fousteri; Jason R. Chan; Yanan Zheng; Chan Whiting; Amy Dave; Damien Bresson; Michael Croft; Matthias von Herrath

Abstracts

View articletitled, Virtual Optimization of Nasal Insulin Therapy Predicts Immunization Frequency to Be Crucial for Diabetes Protection

Supplementary data

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Topics: immunization , interleukin-10 , nose , peptides , regulatory t-lymphocytes

Diabetes September 2010, Vol.59, 3148-3158. doi:https://doi.org/10.2337/db10-0561

Pathophysiology

High Glucose Increases Lysyl Oxidase Expression and Activity in Retinal Endothelial Cells: Mechanism for Compromised Extracellular Matrix Barrier Function

Argyrios Chronopoulos; Amanda Tang; Ekaterina Beglova; Philip C. Trackman; Sayon Roy

Abstracts

View articletitled, High Glucose Increases Lysyl Oxidase Expression and Activity in Retinal Endothelial Cells: Mechanism for Compromised Extracellular Matrix Barrier Function

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Topics: aminopropionitrile , endothelial cells , glucose , immunohistochemistry , permeability

Diabetes September 2010, Vol.59, 3159-3166. doi:https://doi.org/10.2337/db10-0365

Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans

Andreas Peter; Konstantinos Kantartzis; Jürgen Machann; Fritz Schick; Harald Staiger; Fausto Machicao; Erwin Schleicher; Andreas Fritsche; Hans-Ulrich Häring; Norbert Stefan

Abstracts

View articletitled, Relationships of Circulating Sex Hormone–Binding Globulin With Metabolic Traits in Humans

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Topics: sex hormone-binding globulin , liver , oral glucose tolerance test

Diabetes September 2010, Vol.59, 3167-3173. doi:https://doi.org/10.2337/db10-0179

Enterovirus Infection and Progression From Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY)

Lars C. Stene; Sami Oikarinen; Heikki Hyöty; Katherine J. Barriga; Jill M. Norris; Georgeanna Klingensmith; John C. Hutton; Henry A. Erlich; George S. Eisenbarth; Marian Rewers

Abstracts

View articletitled, Enterovirus Infection and Progression From Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY)

Supplementary data

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Topics: autoantibodies , diabetes mellitus, type 1 , enterovirus infections , rna , enterovirus

Diabetes September 2010, Vol.59, 3174-3180. doi:https://doi.org/10.2337/db10-0866

Adipose Tissue Dysfunction Signals Progression of Hepatic Steatosis Towards Nonalcoholic Steatohepatitis in C57Bl/6 Mice

Caroline Duval; Uwe Thissen; Shohreh Keshtkar; Bertrand Accart; Rinke Stienstra; Mark V. Boekschoten; Tania Roskams; Sander Kersten; Michael Müller

Abstracts

View articletitled, Adipose Tissue Dysfunction Signals Progression of Hepatic Steatosis Towards Nonalcoholic Steatohepatitis in C57Bl/6 Mice

Supplementary data

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Topics: adipose tissue , fatty liver , liver , mice , mice, inbred c57bl

Diabetes September 2010, Vol.59, 3181-3191. doi:https://doi.org/10.2337/db10-0224

High Levels of Serum Prolactin Protect Against Diabetic Retinopathy by Increasing Ocular Vasoinhibins

Edith Arnold; José C. Rivera; Stéphanie Thebault; Daniel Moreno-Páramo; Hugo Quiroz-Mercado; Andrés Quintanar-Stéphano; Nadine Binart; Gonzalo Martínez de la Escalera; Carmen Clapp

Abstracts

View articletitled, High Levels of Serum Prolactin Protect Against Diabetic Retinopathy by Increasing Ocular Vasoinhibins

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Topics: diabetic retinopathy , hyperprolactinemia , prolactin , rats , retina

Diabetes September 2010, Vol.59, 3192-3197. doi:https://doi.org/10.2337/db10-0873

Complications

Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse

Phyllis Chew; Derek Y.C. Yuen; Nada Stefanovic; Josefa Pete; Melinda T. Coughlan; Karin A. Jandeleit-Dahm; Merlin C. Thomas; Franklin Rosenfeldt; Mark E. Cooper; Judy B. de Haan

Abstracts

View articletitled, Antiatherosclerotic and Renoprotective Effects of Ebselen in the Diabetic Apolipoprotein E/GPx1-Double Knockout Mouse

Supplementary data

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Topics: apolipoprotein e , ebselen , kidney , 3-nitrotyrosine , mice

Diabetes September 2010, Vol.59, 3198-3207. doi:https://doi.org/10.2337/db10-0195

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

Antonia G. Miller; Genevieve Tan; Katrina J. Binger; Raelene J. Pickering; Merlin C. Thomas; Ram H. Nagaraj; Mark E. Cooper; Jennifer L. Wilkinson-Berka

Abstracts

View articletitled, Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

Supplementary data

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Topics: angiotensin ii , apoptosis , candesartan cilexetil , rats , retina

Diabetes September 2010, Vol.59, 3208-3215. doi:https://doi.org/10.2337/db10-0552

Cause-Specific Mortality Trends in a Large Population-Based Cohort With Long-Standing Childhood-Onset Type 1 Diabetes

Aaron M. Secrest; Dorothy J. Becker; Sheryl F. Kelsey; Ronald E. LaPorte; Trevor J. Orchard

Abstracts

View articletitled, Cause-Specific Mortality Trends in a Large Population-Based Cohort With Long-Standing Childhood-Onset Type 1 Diabetes

Supplementary data

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Topics: diabetes mellitus complications , diabetes mellitus, type 1 , cardiovascular diseases

Diabetes August 2010, Vol.59, 3216-3222. doi:https://doi.org/10.2337/db10-0862

Pharmacology and Therapeutics

Apolipoprotein A-I Mimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation in a Murine Model of Diabetes

Cecilia Morgantini; Satoshi Imaizumi; Victor Grijalva; Mohamad Navab; Alan M. Fogelman; Srinivasa T. Reddy

Abstracts

View articletitled, Apolipoprotein A-I Mimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation in a Murine Model of Diabetes

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Topics: apolipoprotein a-i , apolipoprotein e , atherosclerosis , mice , peptides

Diabetes September 2010, Vol.59, 3223-3228. doi:https://doi.org/10.2337/db10-0844

Common Variants at 10 Genomic Loci Influence Hemoglobin A_1C Levels via Glycemic and Nonglycemic Pathways

Nicole Soranzo; Serena Sanna; Eleanor Wheeler; Christian Gieger; Dörte Radke; Josée Dupuis; Nabila Bouatia-Naji; Claudia Langenberg; Inga Prokopenko; Elliot Stolerman; Manjinder S. Sandhu; Matthew M. Heeney; Joseph M. Devaney; Muredach P. Reilly; Sally L. Ricketts

Abstracts

View articletitled, Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

Supplementary data

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Topics: hemoglobin a, glycosylated , single nucleotide polymorphism , genome

Diabetes September 2010, Vol.59, 3229-3239. doi:https://doi.org/10.2337/db10-0502

Effects of Salsalate Therapy on Recovery From Vascular Injury in Female Zucker Fatty Rats

Subramanyam N. Murthy; Cyrus V. Desouza; Neal W. Bost; Rose-Claire St. Hilaire; David B. Casey; Adeleke M. Badejo; Jasdeep S. Dhaliwal; Jennifer McGee; Dennis B. McNamara; Philip J. Kadowitz; Vivian A. Fonseca

Abstracts

View articletitled, Effects of Salsalate Therapy on Recovery From Vascular Injury in Female Zucker Fatty Rats

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Topics: balloon dilatation catheters , rats , salicylsalicylic acid , western blotting , vascular endothelial growth factor a

Diabetes September 2010, Vol.59, 3240-3246. doi:https://doi.org/10.2337/db09-1761

Genetics

Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion

Martin Heni; Caroline Ketterer; Claus Thamer; Silke A. Herzberg-Schäfer; Martina Guthoff; Norbert Stefan; Fausto Machicao; Harald Staiger; Andreas Fritsche; Hans-Ulrich Häring

Abstracts

View articletitled, Glycemia Determines the Effect of Type 2 Diabetes Risk Genes on Insulin Secretion

Supplementary data

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Topics: diabetes mellitus, type 2 , genes , glucose , insulin secretion , oral glucose tolerance test

Diabetes August 2010, Vol.59, 3247-3252. doi:https://doi.org/10.2337/db10-0674

Effect of HLA Class I and Class II Alleles on Progression From Autoantibody Positivity to Overt Type 1 Diabetes in Children With Risk-Associated Class II Genotypes

Kati Lipponen; Zsofia Gombos; Minna Kiviniemi; Heli Siljander; Johanna Lempainen; Robert Hermann; Riitta Veijola; Olli Simell; Mikael Knip; Jorma Ilonen

Abstracts

View articletitled, Effect of HLA Class I and Class II Alleles on Progression From Autoantibody Positivity to Overt Type 1 Diabetes in Children With Risk-Associated Class II Genotypes

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Topics: alleles , autoantibodies , child , diabetes mellitus, type 1 , genotype

Diabetes August 2010, Vol.59, 3253-3256. doi:https://doi.org/10.2337/db10-0167

Erratum

Extract

View articletitled, Erratum

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Topics: beijing , china , cyclophosphamide, doxorubicin, prednisone, and vincristine , hospitals, pediatric , pancreas

Diabetes December 2010, Vol.59, 3257. doi:https://doi.org/10.2337/db10-er12

Online Letters to The Editor

Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

Kristina I. Rother; David M. Harlan

Extract

View articletitled, Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

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Topics: insulin , pancreas

Diabetes December 2010, Vol.59, e26. doi:https://doi.org/10.2337/db10-1207

Response to Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

Hillary A. Keenan; Susan Bonner-Weir; George L. King

Extract

View articletitled, Response to Comment on: Keenan et al. (2010) Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study. Diabetes 2010;59:2846–2853

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Topics: insulin , pancreas

Diabetes December 2010, Vol.59, e27. doi:https://doi.org/10.2337/db10-1277

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