Skip Nav Destination
Issues
Commentaries
SIRT1 Takes a Backseat to AMPK in the Regulation of Insulin Sensitivity by Resveratrol
Diabetes March 2010, Vol.59, 551-553. doi:https://doi.org/10.2337/db09-1732
Original Article
Metabolism
AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
Jee-Hyun Um; Sung-Jun Park; Hyeog Kang; Shutong Yang; Marc Foretz; Michael W. McBurney; Myung K. Kim; Benoit Viollet; Jay H. Chung
Diabetes November 2009, Vol.59, 554-563. doi:https://doi.org/10.2337/db09-0482
A Possible Inflammatory Role of Twist1 in Human White Adipocytes
Amanda T. Pettersson; Jurga Laurencikiene; Niklas Mejhert; Erik Näslund; Anne Bouloumié; Ingrid Dahlman; Peter Arner; Mikael Rydén
Diabetes December 2009, Vol.59, 564-571. doi:https://doi.org/10.2337/db09-0997
Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity
Ruth C.R. Meex; Vera B. Schrauwen-Hinderling; Esther Moonen-Kornips; Gert Schaart; Marco Mensink; Esther Phielix; Tineke van de Weijer; Jean-Pierre Sels; Patrick Schrauwen; Matthijs K.C. Hesselink
Diabetes December 2009, Vol.59, 572-579. doi:https://doi.org/10.2337/db09-1322
Insulin Acutely Inhibits Intestinal Lipoprotein Secretion in Humans in Part by Suppressing Plasma Free Fatty Acids
Diabetes December 2009, Vol.59, 580-587. doi:https://doi.org/10.2337/db09-1297
Signal Transduction
Plasma Membrane Subdomain Compartmentalization Contributes to Distinct Mechanisms of Ceramide Action on Insulin Signaling
Cédric M. Blouin; Cécilia Prado; Karen K. Takane; Françoise Lasnier; Adolfo Garcia-Ocana; Pascal Ferré; Isabelle Dugail; Eric Hajduch
Diabetes December 2009, Vol.59, 600-610. doi:https://doi.org/10.2337/db09-0897
Obesity Studies
Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women: A Prospective Study
Diabetes December 2009, Vol.59, 611-618. doi:https://doi.org/10.2337/db09-1343
Diet-Induced Obesity Prevents Interstitial Dispersion of Insulin in Skeletal Muscle
Cathryn M. Kolka; L. Nicole Harrison; Maya Lottati; Jenny D. Chiu; Erlinda L. Kirkman; Richard N. Bergman
Diabetes December 2009, Vol.59, 619-626. doi:https://doi.org/10.2337/db09-0839
Metabolic Changes Following a 1-Year Diet and Exercise Intervention in Patients With Type 2 Diabetes
Jeanine B. Albu; Leonie K. Heilbronn; David E. Kelley; Steven R. Smith; Koichiro Azuma; Evan S. Berk; F. Xavier Pi-Sunyer; Eric Ravussin; the Look AHEAD Adipose Research Group
Diabetes December 2009, Vol.59, 627-633. doi:https://doi.org/10.2337/db09-1239
Immunology and Transplantation
CD14+ Monocytes Are Vulnerable and Functionally Impaired Under Endoplasmic Reticulum Stress in Patients With Type 2 Diabetes
Diabetes December 2009, Vol.59, 634-643. doi:https://doi.org/10.2337/db09-0659
Islet Studies
Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax
Mark D. McKenzie; Emma Jamieson; Elisa S. Jansen; Clare L. Scott; David C.S. Huang; Philippe Bouillet; Janette Allison; Thomas W.H. Kay; Andreas Strasser; Helen E. Thomas
Diabetes December 2009, Vol.59, 644-652. doi:https://doi.org/10.2337/db09-1151
Insulin Gene Mutations Resulting in Early-Onset Diabetes: Marked Differences in Clinical Presentation, Metabolic Status, and Pathogenic Effect Through Endoplasmic Reticulum Retention
Gargi Meur; Albane Simon; Nasret Harun; Marie Virally; Aurélie Dechaume; Amélie Bonnefond; Sabrina Fetita; Andrei I. Tarasov; Pierre-Jean Guillausseau; Trine Welløv Boesgaard; Oluf Pedersen; Torben Hansen; Michel Polak; Jean-François Gautier; Philippe Froguel; Guy A. Rutter; Martine Vaxillaire
Diabetes December 2009, Vol.59, 653-661. doi:https://doi.org/10.2337/db09-1091
Pathophysiology
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
Markus A. Queisser; Dachun Yao; Sven Geisler; Hans-Peter Hammes; Günter Lochnit; Erwin D. Schleicher; Michael Brownlee; Klaus T. Preissner
Diabetes December 2009, Vol.59, 670-678. doi:https://doi.org/10.2337/db08-1565
Progression to Diabetes in Relatives of Type 1 Diabetic Patients: Mechanisms and Mode of Onset
Ele Ferrannini; Andrea Mari; Valentina Nofrate; Jay M. Sosenko; Jay S. Skyler; for the DPT-1 Study Group
Diabetes December 2009, Vol.59, 679-685. doi:https://doi.org/10.2337/db09-1378
Complications
Insulin-Sensitizing Therapy Attenuates Type 2 Diabetes–Mediated Mammary Tumor Progression
Diabetes December 2009, Vol.59, 686-693. doi:https://doi.org/10.2337/db09-1291
Increased Vitreous Shedding of Microparticles in Proliferative Diabetic Retinopathy Stimulates Endothelial Proliferation
Sadri Chahed; Aurélie S. Leroyer; Mounir Benzerroug; David Gaucher; Adriana Georgescu; Serge Picaud; Jean-Sébastien Silvestre; Alain Gaudric; Alain Tedgui; Pascale Massin; Chantal M. Boulanger
Diabetes December 2009, Vol.59, 694-701. doi:https://doi.org/10.2337/db08-1524
Cerebral Metabolic Alterations in Rats With Diabetic Ketoacidosis: Effects of Treatment With Insulin and Intravenous Fluids and Effects of Bumetanide
Diabetes December 2009, Vol.59, 702-709. doi:https://doi.org/10.2337/db09-0635
Pharmacology and Therapeutics
A Central Role of RLIP76 in Regulation of Glycemic Control
Sanjay Awasthi; Sharad S. Singhal; Sushma Yadav; Jyotsana Singhal; Rit Vatsyayan; Ewa Zajac; Rafal Luchowski; Jozef Borvak; Karol Gryczynski; Yogesh C. Awasthi
Diabetes December 2009, Vol.59, 714-725. doi:https://doi.org/10.2337/db09-0911
Genetics
Genetic Variation at the FTO Locus Influences RBL2 Gene Expression
Jeremy B.M. Jowett; Joanne E. Curran; Matthew P. Johnson; Melanie A. Carless; Harald H.H. Göring; Thomas D. Dyer; Shelley A. Cole; Anthony G. Comuzzie; Jean W. MacCluer; Eric K. Moses; John Blangero
Diabetes December 2009, Vol.59, 726-732. doi:https://doi.org/10.2337/db09-1277
A Novel Hypomorphic PDX1 Mutation Responsible for Permanent Neonatal Diabetes With Subclinical Exocrine Deficiency
Diabetes December 2009, Vol.59, 733-740. doi:https://doi.org/10.2337/db09-1284
Brief Report
Complications
Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study
Riccardo E. Marioni; Mark W.J. Strachan; Rebecca M. Reynolds; Gordon D.O. Lowe; Rory J. Mitchell; F. Gerry R. Fowkes; Brian M. Frier; Amanda J. Lee; Isabella Butcher; Ann Rumley; Gordon D. Murray; Ian J. Deary; Jackie F. Price
Diabetes December 2009, Vol.59, 710-713. doi:https://doi.org/10.2337/db09-1163
Genetics
Detailed Investigation of the Role of Common and Low-Frequency WFS1 Variants in Type 2 Diabetes Risk
Katherine A. Fawcett; Eleanor Wheeler; Andrew P. Morris; Sally L. Ricketts; Göran Hallmans; Olov Rolandsson; Allan Daly; Jon Wasson; Alan Permutt; Andrew T. Hattersley; Benjamin Glaser; Paul W. Franks; Mark I. McCarthy; Nicholas J. Wareham; Manjinder S. Sandhu; Inês Barroso
Diabetes December 2009, Vol.59, 741-746. doi:https://doi.org/10.2337/db09-0920
Gene Variants of TCF7L2 Influence Weight Loss and Body Composition During Lifestyle Intervention in a Population at Risk for Type 2 Diabetes
Axel Haupt; Claus Thamer; Martin Heni; Caroline Ketterer; Jürgen Machann; Fritz Schick; Fausto Machicao; Norbert Stefan; Claus D. Claussen; Hans-Ulrich Häring; Andreas Fritsche; Harald Staiger
Diabetes December 2009, Vol.59, 747-750. doi:https://doi.org/10.2337/db09-1050
Examination of All Type 2 Diabetes GWAS Loci Reveals HHEX-IDE as a Locus Influencing Pediatric BMI
Jianhua Zhao; Jonathan P. Bradfield; Haitao Zhang; Kiran Annaiah; Kai Wang; Cecilia E. Kim; Joseph T. Glessner; Edward C. Frackelton; F. George Otieno; James Doran; Kelly A. Thomas; Maria Garris; Cuiping Hou; Rosetta M. Chiavacci; Mingyao Li; Robert I. Berkowitz; Hakon Hakonarson; Struan F.A. Grant
Diabetes November 2009, Vol.59, 751-755. doi:https://doi.org/10.2337/db09-0972
