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Volume 61, Issue 11
1 November 2012
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ISSN 0012-1797
EISSN 1939-327X
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Commentary

Understanding the Elusive Mechanism of Action of TCF7L2 in Metabolism
Struan F.A. Grant
View articletitled, Understanding the Elusive Mechanism of Action of TCF7L2 in Metabolism
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Diabetes October 2012, Vol.61, 2657-2658. doi:https://doi.org/10.2337/db12-0891
Seeing Is Believing: Dietary Fatty Acids Hurry Up From the Stomach to the Heart of Patients With Impaired Glucose Tolerance
Patricia Iozzo
View articletitled, Seeing Is Believing: Dietary Fatty Acids Hurry Up From the Stomach to the Heart of Patients With Impaired Glucose Tolerance
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Diabetes October 2012, Vol.61, 2659-2660. doi:https://doi.org/10.2337/db12-0803

Methodology Reviews

Muscle Perfusion: Its Measurement and Role in Metabolic Regulation
Eugene J. Barrett; Stephen Rattigan
View articletitled, Muscle Perfusion<span class="subtitle-colon">: </span><span class="subtitle">Its Measurement and Role in Metabolic Regulation</span>
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Diabetes October 2012, Vol.61, 2661-2668. doi:https://doi.org/10.2337/db12-0271
31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism
Douglas E. Befroy; Douglas L. Rothman; Kitt Falk Petersen; Gerald I. Shulman
View articletitled, <sup>31</sup>P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism
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Diabetes October 2012, Vol.61, 2669-2678. doi:https://doi.org/10.2337/db12-0558

Metabolism

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels
Madeleen Bosma; Matthijs K.C. Hesselink; Lauren M. Sparks; Silvie Timmers; Maria João Ferraz; Frits Mattijssen; Denis van Beurden; Gert Schaart; Marc H. de Baets; Fons K. Verheyen; Sander Kersten; Patrick Schrauwen
View articletitled, Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels
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Diabetes October 2012, Vol.61, 2679-2690. doi:https://doi.org/10.2337/db11-1402
Diurnal Pattern to Insulin Secretion and Insulin Action in Healthy Individuals
Ahmed Saad; Chiara Dalla Man; Debashis K. Nandy; James A. Levine; Adil E. Bharucha; Robert A. Rizza; Rita Basu; Rickey E. Carter; Claudio Cobelli; Yogish C. Kudva; Ananda Basu
View articletitled, Diurnal Pattern to Insulin Secretion and Insulin Action in Healthy Individuals
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Diabetes October 2012, Vol.61, 2691-2700. doi:https://doi.org/10.2337/db11-1478
Increased Myocardial Uptake of Dietary Fatty Acids Linked to Cardiac Dysfunction in Glucose-Intolerant Humans
Sébastien M. Labbé; Thomas Grenier-Larouche; Christophe Noll; Serge Phoenix; Brigitte Guérin; Eric E. Turcotte; André C. Carpentier
View articletitled, Increased Myocardial Uptake of Dietary Fatty Acids Linked to Cardiac Dysfunction in Glucose-Intolerant Humans
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Diabetes October 2012, Vol.61, 2701-2710. doi:https://doi.org/10.2337/db11-1805
Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly
Clare Flannery; Sylvie Dufour; Rasmus Rabøl; Gerald I. Shulman; Kitt Falk Petersen
View articletitled, Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly
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Diabetes October 2012, Vol.61, 2711-2717. doi:https://doi.org/10.2337/db12-0206
Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages
Jeb S. Orr; Michael J. Puglisi; Kate L.J. Ellacott; Carey N. Lumeng; David H. Wasserman; Alyssa H. Hasty
View articletitled, Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages
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Diabetes October 2012, Vol.61, 2718-2727. doi:https://doi.org/10.2337/db11-1595
Effect of Glycemia on Plasma Incretins and the Incretin Effect During Oral Glucose Tolerance Test
Marzieh Salehi; Benedict Aulinger; David A. D’Alessio
View articletitled, Effect of Glycemia on Plasma Incretins and the Incretin Effect During Oral Glucose Tolerance Test
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Diabetes October 2012, Vol.61, 2728-2733. doi:https://doi.org/10.2337/db11-1825
Caloric Restriction Chronically Impairs Metabolic Programming in Mice
Henriette Kirchner; Susanna M. Hofmann; Antje Fischer-Rosinský; Jazzminn Hembree; William Abplanalp; Nickki Ottaway; Elizabeth Donelan; Radha Krishna; Stephen C. Woods; Timo D. Müller; Joachim Spranger; Diego Perez-Tilve; Paul T. Pfluger; Matthias H. Tschöp; Kirk M. Habegger
View articletitled, Caloric Restriction Chronically Impairs Metabolic Programming in Mice
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Diabetes October 2012, Vol.61, 2734-2742. doi:https://doi.org/10.2337/db11-1621
Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle–Signaling Interaction at the Level of TBC1 Domain Family Member 4
Christian Pehmøller; Nina Brandt; Jesper B. Birk; Louise D. Høeg; Kim A. Sjøberg; Laurie J. Goodyear; Bente Kiens; Erik A. Richter; Jørgen F.P. Wojtaszewski
View articletitled, Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle–Signaling Interaction at the Level of TBC1 Domain Family Member 4
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Diabetes October 2012, Vol.61, 2743-2752. doi:https://doi.org/10.2337/db11-1572
Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
Sarah H. Lockie; Kristy M. Heppner; Nilika Chaudhary; Joseph R. Chabenne; Donald A. Morgan; Christelle Veyrat-Durebex; Gayathri Ananthakrishnan; Françoise Rohner-Jeanrenaud; Daniel J. Drucker; Richard DiMarchi; Kamal Rahmouni; Brian J. Oldfield; Matthias H. Tschöp; Diego Perez-Tilve
View articletitled, Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
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Diabetes October 2012, Vol.61, 2753-2762. doi:https://doi.org/10.2337/db11-1556

Signal Transduction

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
Daniel A. Cunha; Mariana Igoillo-Esteve; Esteban N. Gurzov; Carla M. Germano; Najib Naamane; Ihsane Marhfour; Makiko Fukaya; Jean-Marie Vanderwinden; Conny Gysemans; Chantal Mathieu; Lorella Marselli; Piero Marchetti; Heather P. Harding; David Ron; Décio L. Eizirik; Miriam Cnop
View articletitled, Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
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Diabetes October 2012, Vol.61, 2763-2775. doi:https://doi.org/10.2337/db12-0123

Obesity Studies

Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance
Meilian Liu; Ruihua Xiang; Sarah Ann Wilk; Ning Zhang; Lauren B. Sloane; Kian Azarnoush; Lijun Zhou; Hongzhi Chen; Guangda Xiang; Christi A. Walter; Steven N. Austad; Nicolas Musi; Ralph A. DeFronzo; Reto Asmis; Philipp E. Scherer; Lily Q. Dong; Feng Liu
View articletitled, Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance
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Diabetes October 2012, Vol.61, 2776-2786. doi:https://doi.org/10.2337/db12-0169
Effects of Aerobic Versus Resistance Exercise Without Caloric Restriction on Abdominal Fat, Intrahepatic Lipid, and Insulin Sensitivity in Obese Adolescent Boys: A Randomized, Controlled Trial
SoJung Lee; Fida Bacha; Tamara Hannon; Jennifer L. Kuk; Chris Boesch; Silva Arslanian
View articletitled, Effects of Aerobic Versus Resistance Exercise Without Caloric Restriction on Abdominal Fat, Intrahepatic Lipid, and Insulin Sensitivity in Obese Adolescent Boys<span class="subtitle-colon">: </span><span class="subtitle">A Randomized, Controlled Trial</span>
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Diabetes October 2012, Vol.61, 2787-2795. doi:https://doi.org/10.2337/db12-0214
Depressed Levels of Prostaglandin F2α in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity
Fanny E. Volat; Jean-Christophe Pointud; Emilie Pastel; Béatrice Morio; Benoit Sion; Ghislaine Hamard; Michel Guichardant; Romain Colas; Anne-Marie Lefrançois-Martinez; Antoine Martinez
View articletitled, Depressed Levels of Prostaglandin F<sub>2α</sub> in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity
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Diabetes October 2012, Vol.61, 2796-2806. doi:https://doi.org/10.2337/db11-1297
Adipose Tissue TCF7L2 Splicing Is Regulated by Weight Loss and Associates With Glucose and Fatty Acid Metabolism
Dorota Kaminska; Tiina Kuulasmaa; Sari Venesmaa; Pirjo Käkelä; Maija Vaittinen; Leena Pulkkinen; Matti Pääkkönen; Helena Gylling; Markku Laakso; Jussi Pihlajamäki
View articletitled, Adipose Tissue <em>TCF7L2</em> Splicing Is Regulated by Weight Loss and Associates With Glucose and Fatty Acid Metabolism
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Diabetes October 2012, Vol.61, 2807-2813. doi:https://doi.org/10.2337/db12-0239
Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte Proliferation
Sussi B. Mortensen; Charlotte H. Jensen; Mikael Schneider; Mads Thomassen; Torben A. Kruse; Jorge Laborda; Søren P. Sheikh; Ditte C. Andersen
View articletitled, Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte Proliferation
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Diabetes October 2012, Vol.61, 2814-2822. doi:https://doi.org/10.2337/db12-0176
Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex
Atsuko Nakatsuka; Jun Wada; Izumi Iseda; Sanae Teshigawara; Kanji Higashio; Kazutoshi Murakami; Motoko Kanzaki; Kentaro Inoue; Takahiro Terami; Akihiro Katayama; Kazuyuki Hida; Jun Eguchi; Chikage Sato Horiguchi; Daisuke Ogawa; Yasushi Matsuki; Ryuji Hiramatsu; Hideo Yagita; Shigeru Kakuta; Yoichiro Iwakura; Hirofumi Makino
View articletitled, Vaspin Is an Adipokine Ameliorating ER Stress in Obesity as a Ligand for Cell-Surface GRP78/MTJ-1 Complex
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Diabetes October 2012, Vol.61, 2823-2832. doi:https://doi.org/10.2337/db12-0232
Maternal High-Fat Diet During Gestation or Suckling Differentially Affects Offspring Leptin Sensitivity and Obesity
Bo Sun; Ryan H. Purcell; Chantelle E. Terrillion; Jianqun Yan; Timothy H. Moran; Kellie L.K. Tamashiro
View articletitled, Maternal High-Fat Diet During Gestation or Suckling Differentially Affects Offspring Leptin Sensitivity and Obesity
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Diabetes October 2012, Vol.61, 2833-2841. doi:https://doi.org/10.2337/db11-0957

Islet Studies

NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion
Ning Li; Bin Li; Thierry Brun; Christine Deffert-Delbouille; Zahia Mahiout; Youssef Daali; Xiao-Juan Ma; Karl-Heinz Krause; Pierre Maechler
View articletitled, NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion
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Diabetes October 2012, Vol.61, 2842-2850. doi:https://doi.org/10.2337/db12-0009
Vascular Endothelial Growth Factor–Mediated Islet Hypervascularization and Inflammation Contribute to Progressive Reduction of β-Cell Mass
Judith Agudo; Eduard Ayuso; Veronica Jimenez; Alba Casellas; Cristina Mallol; Ariana Salavert; Sabrina Tafuro; Mercè Obach; Albert Ruzo; Marta Moya; Anna Pujol; Fatima Bosch
View articletitled, Vascular Endothelial Growth Factor–Mediated Islet Hypervascularization and Inflammation Contribute to Progressive Reduction of β-Cell Mass
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Diabetes October 2012, Vol.61, 2851-2861. doi:https://doi.org/10.2337/db12-0134

Immunology and Transplantation

Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells
Vineeth Varanasi; Lia Avanesyan; Desiree M. Schumann; Alexander V. Chervonsky
View articletitled, Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic β-Cells
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Diabetes October 2012, Vol.61, 2862-2870. doi:https://doi.org/10.2337/db11-1784
Long-Term Remission of Diabetes in NOD Mice Is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies
Zuoan Yi; Ramiro Diz; Aaron J. Martin; Yves Maurice Morillon; Douglas E. Kline; Li Li; Bo Wang; Roland Tisch
View articletitled, Long-Term Remission of Diabetes in NOD Mice Is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies
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Diabetes October 2012, Vol.61, 2871-2880. doi:https://doi.org/10.2337/db12-0098
Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice
Roham Parsa; Pernilla Andresen; Alan Gillett; Sohel Mia; Xing-Mei Zhang; Sofia Mayans; Dan Holmberg; Robert A. Harris
View articletitled, Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice
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Diabetes October 2012, Vol.61, 2881-2892. doi:https://doi.org/10.2337/db11-1635
B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes
Eliana Mariño; Bernice Tan; Lauren Binge; Charles R. Mackay; Shane T. Grey
View articletitled, B-Cell Cross-Presentation of Autologous Antigen Precipitates Diabetes
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Diabetes October 2012, Vol.61, 2893-2905. doi:https://doi.org/10.2337/db12-0006

Pathophysiology

The Role of MicroRNA-146a in the Pathogenesis of the Diabetic Wound-Healing Impairment: Correction With Mesenchymal Stem Cell Treatment
Junwang Xu; Wenjie Wu; Liping Zhang; Wanda Dorset-Martin; Michael W. Morris; Marc E. Mitchell; Kenneth W. Liechty
View articletitled, The Role of MicroRNA-146a in the Pathogenesis of the Diabetic Wound-Healing Impairment<span class="subtitle-colon">: </span><span class="subtitle">Correction With Mesenchymal Stem Cell Treatment</span>
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Diabetes October 2012, Vol.61, 2906-2912. doi:https://doi.org/10.2337/db12-0145
High Glucose Inhibits the Aspirin-Induced Activation of the Nitric Oxide/cGMP/cGMP-Dependent Protein Kinase Pathway and Does Not Affect the Aspirin-Induced Inhibition of Thromboxane Synthesis in Human Platelets
Isabella Russo; Michela Viretto; Cristina Barale; Luigi Mattiello; Gabriella Doronzo; Andrea Pagliarino; Franco Cavalot; Mariella Trovati; Giovanni Anfossi
View articletitled, High Glucose Inhibits the Aspirin-Induced Activation of the Nitric Oxide/cGMP/cGMP-Dependent Protein Kinase Pathway and Does Not Affect the Aspirin-Induced Inhibition of Thromboxane Synthesis in Human Platelets
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Diabetes October 2012, Vol.61, 2913-2921. doi:https://doi.org/10.2337/db12-0040
Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations
Angela R. Subauste; Arun K. Das; Xiangquan Li; Brandon Elliot; Charles Evans; Mahmoud El Azzouny; Mary Treutelaar; Elif Oral; Todd Leff; Charles F. Burant
View articletitled, Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations
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Diabetes October 2012, Vol.61, 2922-2931. doi:https://doi.org/10.2337/db12-0004
C1q/TNF-Related Protein-3 (CTRP-3) and Pigment Epithelium-Derived Factor (PEDF) Concentrations in Patients With Type 2 Diabetes and Metabolic Syndrome
Kyung Mook Choi; Soon Young Hwang; Ho Cheol Hong; Sae Jeong Yang; Hae Yoon Choi; Hye Jin Yoo; Kwan Woo Lee; Moon Suk Nam; Yong Soo Park; Jeong Taek Woo; Young Seol Kim; Dong Seop Choi; Byung-Soo Youn; Sei Hyun Baik
View articletitled, C1q/TNF-Related Protein-3 (CTRP-3) and Pigment Epithelium-Derived Factor (PEDF) Concentrations in Patients With Type 2 Diabetes and Metabolic Syndrome
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Diabetes October 2012, Vol.61, 2932-2936. doi:https://doi.org/10.2337/db12-0217

Complications

Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
Thanh Dinh; Francesco Tecilazich; Antonios Kafanas; John Doupis; Charalambos Gnardellis; Ermelindo Leal; Ana Tellechea; Leena Pradhan; Thomas E. Lyons; John M. Giurini; Aristidis Veves
View articletitled, Mechanisms Involved in the Development and Healing of Diabetic Foot Ulceration
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Diabetes October 2012, Vol.61, 2937-2947. doi:https://doi.org/10.2337/db12-0227
Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy
Kyungwon Lee; Yang Hu; Lexi Ding; Ying Chen; Yusuke Takahashi; Robert Mott; Jian-xing Ma
View articletitled, Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy
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Diabetes October 2012, Vol.61, 2948-2957. doi:https://doi.org/10.2337/db11-0300
Vegfa Protects the Glomerular Microvasculature in Diabetes
Gavasker A. Sivaskandarajah; Marie Jeansson; Yoshiro Maezawa; Vera Eremina; Hans J. Baelde; Susan E. Quaggin
View articletitled, Vegfa Protects the Glomerular Microvasculature in Diabetes
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Diabetes October 2012, Vol.61, 2958-2966. doi:https://doi.org/10.2337/DB11-1655
Protective Effects of GLP-1 on Glomerular Endothelium and Its Inhibition by PKCβ Activation in Diabetes
Akira Mima; Junko Hiraoka-Yamomoto; Qian Li; Munehiro Kitada; Chenzhong Li; Pedro Geraldes; Motonobu Matsumoto; Koji Mizutani; Kyoungmin Park; Christopher Cahill; Shin-Ichi Nishikawa; Christian Rask-Madsen; George L. King
View articletitled, Protective Effects of GLP-1 on Glomerular Endothelium and Its Inhibition by PKCβ Activation in Diabetes
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Diabetes October 2012, Vol.61, 2967-2979. doi:https://doi.org/10.2337/db11-1824
Increased Inner Ear Susceptibility to Noise Injury in Mice With Streptozotocin-Induced Diabetes
Takeshi Fujita; Daisuke Yamashita; Sayaka Katsunuma; Shingo Hasegawa; Hitoshi Tanimoto; Ken-ichi Nibu
View articletitled, Increased Inner Ear Susceptibility to Noise Injury in Mice With Streptozotocin-Induced Diabetes
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Diabetes October 2012, Vol.61, 2980-2986. doi:https://doi.org/10.2337/db11-1845
Improvements in the Life Expectancy of Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study Cohort
Rachel G. Miller; Aaron M. Secrest; Ravi K. Sharma; Thomas J. Songer; Trevor J. Orchard
View articletitled, Improvements in the Life Expectancy of Type 1 Diabetes<span class="subtitle-colon">: </span><span class="subtitle">The Pittsburgh Epidemiology of Diabetes Complications Study Cohort</span>
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Diabetes October 2012, Vol.61, 2987-2992. doi:https://doi.org/10.2337/db11-1625
Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
Antonio Ceriello; Anna Novials; Emilio Ortega; Lucia La Sala; Gemma Pujadas; Roberto Testa; Anna Rita Bonfigli; Katherine Esposito; Dario Giugliano
View articletitled, Evidence That Hyperglycemia After Recovery From Hypoglycemia Worsens Endothelial Function and Increases Oxidative Stress and Inflammation in Healthy Control Subjects and Subjects With Type 1 Diabetes
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Diabetes October 2012, Vol.61, 2993-2997. doi:https://doi.org/10.2337/db12-0224

Genetics / Genomes / Proteomics / Metabolomics

A Prospective Study of Leukocyte Telomere Length and Risk of Type 2 Diabetes in Postmenopausal Women
Nai-chieh Y. You; Brian H. Chen; Yiqing Song; XuYang Lu; Yilin Chen; JoAnn E. Manson; Mo Kang; Barbara V. Howard; Karen L. Margolis; J. David Curb; Lawrence S. Phillips; Marcia L. Stefanick; Lesley F. Tinker; Simin Liu
View articletitled, A Prospective Study of Leukocyte Telomere Length and Risk of Type 2 Diabetes in Postmenopausal Women
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Diabetes October 2012, Vol.61, 2998-3004. doi:https://doi.org/10.2337/db12-0241
Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes
Joanna M.M. Howson; Jason D. Cooper; Deborah J. Smyth; Neil M. Walker; Helen Stevens; Jin-Xiong She; George S. Eisenbarth; Marian Rewers; John A. Todd; Beena Akolkar; Patrick Concannon; Henry A. Erlich; Cécile Julier; Grant Morahan; Jørn Nerup; Concepcion Nierras; Flemming Pociot; Stephen S. Rich; and the Type 1 Diabetes Genetics Consortium
View articletitled, Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes
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Diabetes October 2012, Vol.61, 3012-3017. doi:https://doi.org/10.2337/db11-1694
Constitutive and Inflammatory Immunopeptidome of Pancreatic β-Cells
Nadine L. Dudek; Chor Teck Tan; Dhana G. Gorasia; Nathan P. Croft; Patricia T. Illing; Anthony W. Purcell
View articletitled, Constitutive and Inflammatory Immunopeptidome of Pancreatic β-Cells
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Diabetes October 2012, Vol.61, 3018-3025. doi:https://doi.org/10.2337/db11-1333
Genetic Predisposition to High Blood Pressure Associates With Cardiovascular Complications Among Patients With Type 2 Diabetes: Two Independent Studies
Qibin Qi; John P. Forman; Majken K. Jensen; Alan Flint; Gary C. Curhan; Eric B. Rimm; Frank B. Hu; Lu Qi
View articletitled, Genetic Predisposition to High Blood Pressure Associates With Cardiovascular Complications Among Patients With Type 2 Diabetes<span class="subtitle-colon">: </span><span class="subtitle">Two Independent Studies</span>
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Diabetes October 2012, Vol.61, 3026-3032. doi:https://doi.org/10.2337/db12-0225

Original Research

Genetics / Genomes / Proteomics / Metabolomics
FTO Genotype and 2-Year Change in Body Composition and Fat Distribution in Response to Weight-Loss Diets: The POUNDS LOST Trial
Xiaomin Zhang; Qibin Qi; Cuilin Zhang; Steven R. Smith; Frank B. Hu; Frank M. Sacks; George A. Bray; Lu Qi
View articletitled, <em>FTO</em> Genotype and 2-Year Change in Body Composition and Fat Distribution in Response to Weight-Loss Diets<span class="subtitle-colon">: </span><span class="subtitle">The POUNDS LOST Trial</span>
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Diabetes October 2012, Vol.61, 3005-3011. doi:https://doi.org/10.2337/db11-1799

Issues and Events

Issues and Events
View articletitled, Issues and Events
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Diabetes October 2012, Vol.61, 3033. doi:https://doi.org/10.2337/db12-ie11

Diabetes Digests

Highlights From the Latest in Diabetes Research
View articletitled, Highlights From the Latest in Diabetes Research
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Diabetes October 2012, Vol.61, 3034-3035. doi:https://doi.org/10.2337/db12-dd11
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities
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