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Issues

Volume 61, Issue 3
1 March 2012
Diabetes Cover Image for Volume 61, Issue 3
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ISSN 0012-1797
EISSN 1939-327X
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Perspectives in Diabetes

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications
Ryoji Nagai; David B. Murray; Thomas O. Metz; John W. Baynes
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Diabetes February 2012, Vol.61, 549-559. doi:https://doi.org/10.2337/db11-1120

Commentary

Does Inhibition of β-Cell Proliferation by Free Fatty Acid in Mice Explain the Progressive Failure of Insulin Secretion in Type 2 Diabetes?
Guenther Boden
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Diabetes February 2012, Vol.61, 560-561. doi:https://doi.org/10.2337/db11-1613
Predicting Diabetes Using Measures of β-Cell Function
Adrian Vella; Alan R. Zinsmeister
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Diabetes February 2012, Vol.61, 562-563. doi:https://doi.org/10.2337/db11-1785
Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion
Owen Chan; Robert S. Sherwin
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Diabetes February 2012, Vol.61, 564-565. doi:https://doi.org/10.2337/db11-1846

Metabolism

Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses
Zheng Chen; Liang Sheng; Hong Shen; Yujun Zhao; Shaomeng Wang; Robert Brink; Liangyou Rui
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Diabetes February 2012, Vol.61, 566-573. doi:https://doi.org/10.2337/db11-0474

Signal Transduction

Glucose-Induced Nuclear Shuttling of ChREBP Is Mediated by Sorcin and Ca2+ Ions in Pancreatic β-Cells
Nafeesa A. Noordeen; Gargi Meur; Guy A. Rutter; Isabelle Leclerc
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Diabetes February 2012, Vol.61, 574-585. doi:https://doi.org/10.2337/db10-1329
Thiazolidinedione Treatment Decreases Oxidative Stress in Spontaneously Hypertensive Heart Failure Rats Through Attenuation of Inducible Nitric Oxide Synthase–Mediated Lipid Radical Formation
Maria B. Kadiiska; Marcelo G. Bonini; Christine Ruggiero; Ellen Cleland; Shawna Wicks; Krisztian Stadler
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Diabetes February 2012, Vol.61, 586-596. doi:https://doi.org/10.2337/db11-1091
Bioactives of Artemisia dracunculus L. Mitigate the Role of Ceramides in Attenuating Insulin Signaling in Rat Skeletal Muscle Cells
Diana N. Obanda; Amy Hernandez; David Ribnicky; Yongmei Yu; Xian H. Zhang; Zhong Q. Wang; William T. Cefalu
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Diabetes February 2012, Vol.61, 597-605. doi:https://doi.org/10.2337/db11-0396

Obesity Studies

Evidence for Early Defects in Insulin Sensitivity and Secretion Before the Onset of Glucose Dysregulation in Obese Youths : A Longitudinal Study
Cosimo Giannini; Ram Weiss; Anna Cali; Riccardo Bonadonna; Nicola Santoro; Bridget Pierpont; Melissa Shaw; Sonia Caprio
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Diabetes February 2012, Vol.61, 606-614. doi:https://doi.org/10.2337/db11-1111
Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance
Tina Märker; Henrike Sell; Pia Zilleßen; Anja Glöde; Jennifer Kriebel; D. Margriet Ouwens; Piet Pattyn; Johannes Ruige; Susanne Famulla; Michael Roden; Jürgen Eckel; Christiane Habich
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Diabetes February 2012, Vol.61, 615-625. doi:https://doi.org/10.2337/db10-1574
Common Variants of IL6, LEPR, and PBEF1 Are Associated With Obesity in Indian Children
Rubina Tabassum; Yuvaraj Mahendran; Om Prakash Dwivedi; Ganesh Chauhan; Saurabh Ghosh; Raman K. Marwaha; Nikhil Tandon; Dwaipayan Bharadwaj
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Diabetes February 2012, Vol.61, 626-631. doi:https://doi.org/10.2337/db11-1501

Islet Studies

Free Fatty Acids Block Glucose-Induced β-Cell Proliferation in Mice by Inducing Cell Cycle Inhibitors p16 and p18
Jordan Pascoe; Douglas Hollern; Rachel Stamateris; Munira Abbasi; Lia C. Romano; Baobo Zou; Christopher P. O’Donnell; Adolfo Garcia-Ocana; Laura C. Alonso
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Diabetes February 2012, Vol.61, 632-641. doi:https://doi.org/10.2337/db11-0991
Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure
Sophie Turban; Xiaoxia Liu; Lynne Ramage; Scott P. Webster; Brian R. Walker; Donald R. Dunbar; John J. Mullins; Jonathan R. Seckl; Nicholas M. Morton
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Diabetes February 2012, Vol.61, 642-652. doi:https://doi.org/10.2337/db11-1054
miR-33a Modulates ABCA1 Expression, Cholesterol Accumulation, and Insulin Secretion in Pancreatic Islets
Nadeeja Wijesekara; Lin-hua Zhang; Martin H. Kang; Thomas Abraham; Alpana Bhattacharjee; Garth L. Warnock; C. Bruce Verchere; Michael R. Hayden
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Diabetes February 2012, Vol.61, 653-658. doi:https://doi.org/10.2337/db11-0944
Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
Janine K. Kruit; Nadeeja Wijesekara; Clara Westwell-Roper; Tim Vanmierlo; Willeke de Haan; Alpana Bhattacharjee; Renmei Tang; Cheryl L. Wellington; Dieter LütJohann; James D. Johnson; Liam R. Brunham; C. Bruce Verchere; Michael R. Hayden
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Diabetes February 2012, Vol.61, 659-664. doi:https://doi.org/10.2337/db11-1341

Immunology and Transplantation

Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally Into the Liver: Disruption of Islet Integrity Necessary for Islet Revascularization
Johanna Henriksnäs; Joey Lau; Guangxiang Zang; Per-Olof Berggren; Martin Köhler; Per-Ola Carlsson
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Diabetes February 2012, Vol.61, 665-673. doi:https://doi.org/10.2337/db10-0895
Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant
Subhadra C. Gunawardana; David W. Piston
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Diabetes February 2012, Vol.61, 674-682. doi:https://doi.org/10.2337/db11-0510
Rising Incidence of Type 1 Diabetes Is Associated With Altered Immunophenotype at Diagnosis
Anna E. Long; Kathleen M. Gillespie; Saba Rokni; Polly J. Bingley; Alistair J.K. Williams
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Diabetes February 2012, Vol.61, 683-686. doi:https://doi.org/10.2337/db11-0962

Pathophysiology

Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa
Maarit Oikarinen; Sisko Tauriainen; Sami Oikarinen; Teemu Honkanen; Pekka Collin; Immo Rantala; Markku Mäki; Katri Kaukinen; Heikki Hyöty
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Diabetes February 2012, Vol.61, 687-691. doi:https://doi.org/10.2337/db11-1157
Age-Related Impairment in Insulin Release: The Essential Role of β2-Adrenergic Receptor
Gaetano Santulli; Angela Lombardi; Daniela Sorriento; Antonio Anastasio; Carmine Del Giudice; Pietro Formisano; Francesco Béguinot; Bruno Trimarco; Claudia Miele; Guido Iaccarino
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Diabetes February 2012, Vol.61, 692-701. doi:https://doi.org/10.2337/db11-1027
Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk
Chris R. Cardwell; Jannet Svensson; Thomas Waldhoer; Johnny Ludvigsson; Vaiva Sadauskaitė-Kuehne; Christine L. Roberts; Roger C. Parslow; Emma J.K. Wadsworth; Girts Brigis; Brone Urbonaitė; Edith Schober; Gabriele Devoti; Constantin Ionescu-Tirgoviste; Carine E. de Beaufort; Gyula Soltesz; Chris C. Patterson
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Diabetes February 2012, Vol.61, 702-707. doi:https://doi.org/10.2337/db11-1000

Complications

Glycemic Control and Cardiovascular Mortality in Hemodialysis Patients With Diabetes: A 6-Year Cohort Study
Joni Ricks; Miklos Z. Molnar; Csaba P. Kovesdy; Anuja Shah; Allen R. Nissenson; Mark Williams; Kamyar Kalantar-Zadeh
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Diabetes February 2012, Vol.61, 708-715. doi:https://doi.org/10.2337/db11-1015
Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
Mohanraj Rajesh; Sándor Bátkai; Malek Kechrid; Partha Mukhopadhyay; Wen-Shin Lee; Béla Horváth; Eileen Holovac; Resat Cinar; Lucas Liaudet; Ken Mackie; György Haskó; Pál Pacher
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Diabetes February 2012, Vol.61, 716-727. doi:https://doi.org/10.2337/db11-0477
Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction
Inah Hwang; Jiyoun Lee; Joo Young Huh; Jehyun Park; Hi Bahl Lee; Ye-Shih Ho; Hunjoo Ha
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Diabetes February 2012, Vol.61, 728-738. doi:https://doi.org/10.2337/db11-0584
Gene Expression Differences in Skin Fibroblasts in Identical Twins Discordant for Type 1 Diabetes
M. Luiza Caramori; Youngki Kim; Jason H. Moore; Stephen S. Rich; Josyf C. Mychaleckyj; Nobuaki Kikyo; Michael Mauer
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Diabetes February 2012, Vol.61, 739-744. doi:https://doi.org/10.2337/db11-0617

Genetics / Genomes / Proteomics / Metabolomics

Genetic Predisposition to Dyslipidemia and Type 2 Diabetes Risk in Two Prospective Cohorts
Qibin Qi; Liming Liang; Alessandro Doria; Frank B. Hu; Lu Qi
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Diabetes February 2012, Vol.61, 745-752. doi:https://doi.org/10.2337/db11-1254
Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes
Andrea K. Steck; Randall Wong; Brandie Wagner; Kelly Johnson; Edwin Liu; Jihane Romanos; Cisca Wijmenga; Jill M. Norris; George S. Eisenbarth; Marian J. Rewers
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Diabetes February 2012, Vol.61, 753-758. doi:https://doi.org/10.2337/db11-1228

Erratum

Erratum
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Diabetes February 2012, Vol.61, 759. doi:https://doi.org/10.2337/db12-er03

Issues and Events

Issues and Events
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Diabetes February 2012, Vol.61, 760. doi:https://doi.org/10.2337/db12-ie03
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities
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