Skip Nav Destination
Issues
1 July 2012
-
Cover Image
Cover Image
- PDF Icon PDF LinkTable of Contents
ISSN 0012-1797
EISSN 1939-327X
Commentary
Inherited β-Cell Dysfunction in Lean Individuals With Type 2 Diabetes
Diabetes June 2012, Vol.61, 1659-1660. doi:https://doi.org/10.2337/db12-0373
On the Immense Variety and Complexity of Circumstances Conditioning Pancreatic β-Cell Apoptosis in Type 1 Diabetes
Diabetes June 2012, Vol.61, 1661-1663. doi:https://doi.org/10.2337/db12-0397
Is HOT a Cool Treatment for Type 1 Diabetes?
Diabetes June 2012, Vol.61, 1664-1666. doi:https://doi.org/10.2337/db12-0527
Signal Transduction
Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior
Tina Sartorius; Caroline Ketterer; Stephanie Kullmann; Michelle Balzer; Carola Rotermund; Sonja Binder; Manfred Hallschmid; Jürgen Machann; Fritz Schick; Veronika Somoza; Hubert Preissl; Andreas Fritsche; Hans-Ulrich Häring; Anita M. Hennige
Diabetes June 2012, Vol.61, 1669-1679. doi:https://doi.org/10.2337/db11-1521
Obesity Studies
CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
Hironori Kitade; Kazuki Sawamoto; Mayumi Nagashimada; Hiroshi Inoue; Yasuhiko Yamamoto; Yoshimichi Sai; Toshinari Takamura; Hiroshi Yamamoto; Ken-ichi Miyamoto; Henry N. Ginsberg; Naofumi Mukaida; Shuichi Kaneko; Tsuguhito Ota
Diabetes June 2012, Vol.61, 1680-1690. doi:https://doi.org/10.2337/db11-1506
Intrinsic Differences in Adipocyte Precursor Cells From Different White Fat Depots
Yazmín Macotela; Brice Emanuelli; Marcelo A. Mori; Stephane Gesta; Tim J. Schulz; Yu-Hua Tseng; C. Ronald Kahn
Diabetes June 2012, Vol.61, 1691-1699. doi:https://doi.org/10.2337/db11-1753
Islet Studies
Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse
W. Steven Head; Meredith L. Orseth; Craig S. Nunemaker; Leslie S. Satin; David W. Piston; Richard K.P. Benninger
Diabetes June 2012, Vol.61, 1700-1707. doi:https://doi.org/10.2337/db11-1312
In Vivo Role of Focal Adhesion Kinase in Regulating Pancreatic β-Cell Mass and Function Through Insulin Signaling, Actin Dynamics, and Granule Trafficking
Erica P. Cai; Marina Casimir; Stephanie A. Schroer; Cynthia T. Luk; Sally Yu Shi; Diana Choi; Xiao Qing Dai; Catherine Hajmrle; Aliya F. Spigelman; Dan Zhu; Herbert Y. Gaisano; Patrick E. MacDonald; Minna Woo
Diabetes June 2012, Vol.61, 1708-1718. doi:https://doi.org/10.2337/db11-1344
Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic β-Cells Leads to Relative Hyperinsulinism During Exercise
Diabetes June 2012, Vol.61, 1719-1725. doi:https://doi.org/10.2337/db11-1531
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
Anders H. Rosengren; Matthias Braun; Taman Mahdi; Sofia A. Andersson; Mary E. Travers; Makoto Shigeto; Enming Zhang; Peter Almgren; Claes Ladenvall; Annika S. Axelsson; Anna Edlund; Morten Gram Pedersen; Anna Jonsson; Reshma Ramracheya; Yunzhao Tang; Jonathan N. Walker; Amy Barrett; Paul R.V. Johnson; Valeriya Lyssenko; Mark I. McCarthy; Leif Groop; Albert Salehi; Anna L. Gloyn; Erik Renström; Patrik Rorsman; Lena Eliasson
Diabetes June 2012, Vol.61, 1726-1733. doi:https://doi.org/10.2337/db11-1516
Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes
Koji Okamoto; Naoko Iwasaki; Kent Doi; Eisei Noiri; Yasuhiko Iwamoto; Yasuko Uchigata; Toshiro Fujita; Katsushi Tokunaga
Diabetes June 2012, Vol.61, 1734-1741. doi:https://doi.org/10.2337/db11-1201
Changes in MicroRNA Expression Contribute to Pancreatic β-Cell Dysfunction in Prediabetic NOD Mice
Elodie Roggli; Sonia Gattesco; Dorothée Caille; Claire Briet; Christian Boitard; Paolo Meda; Romano Regazzi
Diabetes June 2012, Vol.61, 1742-1751. doi:https://doi.org/10.2337/db11-1086
Immunology and Transplantation
Circulating Preproinsulin Signal Peptide–Specific CD8 T Cells Restricted by the Susceptibility Molecule HLA-A24 Are Expanded at Onset of Type 1 Diabetes and Kill β-Cells
Deborah Kronenberg; Robin R. Knight; Megan Estorninho; Richard J. Ellis; Michel G. Kester; Arnoud de Ru; Martin Eichmann; Guo C. Huang; Jake Powrie; Colin M. Dayan; Ania Skowera; Peter A. van Veelen; Mark Peakman
Diabetes June 2012, Vol.61, 1752-1759. doi:https://doi.org/10.2337/db11-1520
Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind
Meghan M. Delmastro; Alexis J. Styche; Massimo M. Trucco; Creg J. Workman; Dario A.A. Vignali; Jon D. Piganelli
Diabetes June 2012, Vol.61, 1760-1768. doi:https://doi.org/10.2337/db11-1591
Prevention of Autoimmune Diabetes and Induction of β-Cell Proliferation in NOD Mice by Hyperbaric Oxygen Therapy
Gaetano Faleo; Carmen Fotino; Nicola Bocca; R. Damaris Molano; Elsie Zahr-Akrawi; Judith Molina; Susana Villate; Oliver Umland; Jay S. Skyler; Allison L. Bayer; Camillo Ricordi; Antonello Pileggi
Diabetes June 2012, Vol.61, 1769-1778. doi:https://doi.org/10.2337/db11-0516
ZnT8 Is a Major CD8+ T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes
Émmanuelle Énée; Roland Kratzer; Jean-Baptiste Arnoux; Emilie Barilleau; Yamina Hamel; Christophe Marchi; Jacques Beltrand; Bénédicte Michaud; Lucienne Chatenoud; Jean-Jacques Robert; Peter van Endert
Diabetes June 2012, Vol.61, 1779-1784. doi:https://doi.org/10.2337/db12-0071
Pathophysiology
Serum Apolipoproteins Are Associated With Systemic and Retinal Microvascular Function in People With Diabetes
Muhammad Bayu Sasongko; Tien Y. Wong; Thanh T. Nguyen; Ryo Kawasaki; Alicia J. Jenkins; Jonathan Shaw; Carol Robinson; Jie Jin Wang
Diabetes June 2012, Vol.61, 1785-1792. doi:https://doi.org/10.2337/db11-1272
Xenin-25 Amplifies GIP-Mediated Insulin Secretion in Humans With Normal and Impaired Glucose Tolerance but Not Type 2 Diabetes
Burton M. Wice; Dominic N. Reeds; Hung D. Tran; Dan L. Crimmins; Bruce W. Patterson; Judit Dunai; Michael J. Wallendorf; Jack H. Ladenson; Dennis T. Villareal; Kenneth S. Polonsky
Diabetes June 2012, Vol.61, 1793-1800. doi:https://doi.org/10.2337/db11-1451
Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
Ivet Elias; Sylvie Franckhauser; Tura Ferré; Laia Vilà; Sabrina Tafuro; Sergio Muñoz; Carles Roca; David Ramos; Anna Pujol; Efren Riu; Jesús Ruberte; Fatima Bosch
Diabetes June 2012, Vol.61, 1801-1813. doi:https://doi.org/10.2337/db11-0832
Complications
Resting-State Brain Networks in Type 1 Diabetic Patients With and Without Microangiopathy and Their Relation to Cognitive Functions and Disease Variables
Eelco van Duinkerken; Menno M. Schoonheim; Ernesto J. Sanz-Arigita; Richard G. IJzerman; Annette C. Moll; Frank J. Snoek; Christopher M. Ryan; Martin Klein; Michaela Diamant; Frederik Barkhof
Diabetes June 2012, Vol.61, 1814-1821. doi:https://doi.org/10.2337/db11-1358
Cardiovascular Autonomic Neuropathy and Subclinical Cardiovascular Disease in Normoalbuminuric Type 1 Diabetic Patients
Ulrik Madvig Mogensen; Tonny Jensen; Lars Køber; Henning Kelbæk; Anne Sophie Mathiesen; Ulrik Dixen; Peter Rossing; Jannik Hilsted; Klaus Fuglsang Kofoed
Diabetes June 2012, Vol.61, 1822-1830. doi:https://doi.org/10.2337/db11-1235
Effects of Hyperglycemia and Effects of Ketosis on Cerebral Perfusion, Cerebral Water Distribution, and Cerebral Metabolism
Diabetes June 2012, Vol.61, 1831-1837. doi:https://doi.org/10.2337/db11-1286
Uncoupling Endothelial Nitric Oxide Synthase Is Ameliorated by Green Tea in Experimental Diabetes by Re-establishing Tetrahydrobiopterin Levels
Aline M. Faria; Alexandros Papadimitriou; Kamila C. Silva; Jacqueline M. Lopes de Faria; José B. Lopes de Faria
Diabetes June 2012, Vol.61, 1838-1847. doi:https://doi.org/10.2337/db11-1241
Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
Quan-Jiang Zhang; William L. Holland; Lloyd Wilson; Jason M. Tanner; Devin Kearns; Judd M. Cahoon; Dix Pettey; Jason Losee; Bradlee Duncan; Derrick Gale; Christopher A. Kowalski; Nicholas Deeter; Alexandrea Nichols; Michole Deesing; Colton Arrant; Ting Ruan; Christoph Boehme; Dane R. McCamey; Janvida Rou; Kapil Ambal; Krishna K. Narra; Scott A. Summers; E. Dale Abel; J. David Symons
Diabetes June 2012, Vol.61, 1848-1859. doi:https://doi.org/10.2337/db11-1399
Reactive Oxygen Species Signaling Facilitates FOXO-3a/FBXO-Dependent Vascular BK Channel β1 Subunit Degradation in Diabetic Mice
Diabetes June 2012, Vol.61, 1860-1868. doi:https://doi.org/10.2337/db11-1658
Insulin Rescues Impaired Spermatogenesis via the Hypothalamic-Pituitary-Gonadal Axis in Akita Diabetic Mice and Restores Male Fertility
Diabetes June 2012, Vol.61, 1869-1878. doi:https://doi.org/10.2337/db11-1527
Pharmacology and Therapeutics
PTGS-2–PTGER2/4 Signaling Pathway Partially Protects From Diabetogenic Toxicity of Streptozotocin in Mice
Antje Vennemann; Anemone Gerstner; Niklas Kern; Nerea Ferreiros Bouzas; Shuh Narumiya; Takayuki Maruyama; Rolf M. Nüsing
Diabetes June 2012, Vol.61, 1879-1887. doi:https://doi.org/10.2337/db11-1396
Genetics / Genomes / Proteomics / Metabolomics
A Gene-Family Analysis of 61 Genetic Variants in the Nicotinic Acetylcholine Receptor Genes for Insulin Resistance and Type 2 Diabetes in American Indians
Jingyun Yang; Yun Zhu; Shelley A. Cole; Karin Haack; Ying Zhang; Laura A. Beebe; Barbara V. Howard; Lyle G. Best; Richard B. Devereux; Jeffrey A. Henderson; Patricia Henderson; Elisa T. Lee; Jinying Zhao
Diabetes June 2012, Vol.61, 1888-1894. doi:https://doi.org/10.2337/db11-1393
Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men
Alena Stančáková; Mete Civelek; Niyas K. Saleem; Pasi Soininen; Antti J. Kangas; Henna Cederberg; Jussi Paananen; Jussi Pihlajamäki; Lori L. Bonnycastle; Mario A. Morken; Michael Boehnke; Päivi Pajukanta; Aldons J. Lusis; Francis S. Collins; Johanna Kuusisto; Mika Ala-Korpela; Markku Laakso
Diabetes June 2012, Vol.61, 1895-1902. doi:https://doi.org/10.2337/db11-1378
