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Perspectives in Diabetes

Acylcarnitines: Reflecting or Inflicting Insulin Resistance?

Marieke G. Schooneman; Frédéric M. Vaz; Sander M. Houten; Maarten R. Soeters

Extract

View articletitled, Acylcarnitines: Reflecting or Inflicting Insulin Resistance?

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Topics: carnitine , insulin resistance , insulin , lipids , mitochondria

Diabetes December 2012, Vol.62, 1-8. doi:https://doi.org/10.2337/db12-0466

Recent Lessons Learned From Prevention and Recent-Onset Type 1 Diabetes Immunotherapy Trials

Teodora P. Staeva; Lucienne Chatenoud; Richard Insel; Mark A. Atkinson

Abstracts

View articletitled, Recent Lessons Learned From Prevention and Recent-Onset Type 1 Diabetes Immunotherapy Trials

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Topics: immunotherapy , insulin , diabetes mellitus, type 1 , autoantigens

Diabetes December 2012, Vol.62, 9-17. doi:https://doi.org/10.2337/db12-0562

Commentary

Dual Trade of Bcl-2 and Bcl-x_L in Islet Physiology: Balancing Life and Death With Metabolism Secretion Coupling

Bernat Soria; Benoit R. Gauthier

Abstracts

View articletitled, Dual Trade of Bcl-2 and Bcl-xL in Islet Physiology: Balancing Life and Death With Metabolism Secretion Coupling

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Topics: bcl2 gene , bodily secretions , glucose , metabolism , mitochondria

Diabetes December 2012, Vol.62, 18-21. doi:https://doi.org/10.2337/db12-1023

Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?

Vishwa Deep Dixit

Abstracts

View articletitled, Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?

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Topics: diabetes mellitus, type 2 , inflammasomes , nlr family, pyrin domain-containing 3 protein , caspase-1 , inflammation

Diabetes December 2012, Vol.62, 22-24. doi:https://doi.org/10.2337/db12-1115

Corneal Confocal Microscopy as a Measure of Diabetic Neuropathy

Roni M. Shtein; Brian C. Callaghan

Abstracts

View articletitled, Corneal Confocal Microscopy as a Measure of Diabetic Neuropathy

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Topics: cornea , diabetic neuropathies , microscopy, confocal , neuropathy , skin biopsies

Diabetes December 2012, Vol.62, 25-26. doi:https://doi.org/10.2337/db12-1114

Diabetes in Early Pregnancy: Getting to the Heart of the Matter

Jeffrey S. Gilbert; Christopher T. Banek; Sara A. Babcock; Hans C. Dreyer

Abstracts

View articletitled, Diabetes in Early Pregnancy: Getting to the Heart of the Matter

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Topics: early stage of pregnancy , embryo , heart , hyperglycemia , pregnancy

Diabetes December 2012, Vol.62, 27-28. doi:https://doi.org/10.2337/db12-1117

Clocking in on Diabetic Retinopathy

Mark E. Kleinman; Jayakrishna Ambati

Abstracts

View articletitled, Clocking in on Diabetic Retinopathy

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Topics: diabetic retinopathy , mice , retina

Diabetes December 2012, Vol.62, 29-30. doi:https://doi.org/10.2337/db12-1151

A Transcriptional Blueprint for Human and Murine Diabetic Kidney Disease

Vivek Bhalla; Maria-Gabriela Velez; Glenn M. Chertow

Abstracts

View articletitled, A Transcriptional Blueprint for Human and Murine Diabetic Kidney Disease

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Topics: diabetic nephropathy , mice , transcription, genetic

Diabetes December 2012, Vol.62, 31-33. doi:https://doi.org/10.2337/db12-1121

Regulation of Glycemic Control by Physical Activity: A Role for Mitochondria?

Kevin R. Short

Abstracts

View articletitled, Regulation of Glycemic Control by Physical Activity: A Role for Mitochondria?

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Topics: glycemic control , mitochondria , insulin resistance , mice

Diabetes December 2012, Vol.62, 34-35. doi:https://doi.org/10.2337/db12-1209

Direct Effects of PPARα Agonists on Retinal Inflammation and Angiogenesis May Explain How Fenofibrate Lowers Risk of Severe Proliferative Diabetic Retinopathy

Steven F. Abcouwer

Abstracts

View articletitled, Direct Effects of PPARα Agonists on Retinal Inflammation and Angiogenesis May Explain How Fenofibrate Lowers Risk of Severe Proliferative Diabetic Retinopathy

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Topics: agonists , angiogenesis , fenofibrate , ppar alpha , proliferative diabetic retinopathy

Diabetes December 2012, Vol.62, 36-38. doi:https://doi.org/10.2337/db12-1223

C-Peptide as a Remedy for Diabetic Microangiopathy?

Werner Waldhäusl

Abstracts

View articletitled, C-Peptide as a Remedy for Diabetic Microangiopathy?

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Topics: c-peptide , diabetic microangiopathies

Diabetes December 2012, Vol.62, 39-40. doi:https://doi.org/10.2337/db12-1250

Hemoglobin A_1c in Diabetes: Panacea or Pointless?

David B. Sacks

Extract

View articletitled, Hemoglobin A1c in Diabetes: Panacea or Pointless?

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Topics: hemoglobin a, glycosylated , hemoglobin a

Diabetes December 2012, Vol.62, 41-43. doi:https://doi.org/10.2337/db12-1485

Technological Advances

Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

Patrick F. Antkowiak; Brian K. Stevens; Craig S. Nunemaker; Marcia McDuffie; Frederick H. Epstein

Abstract

View articletitled, Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes

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Topics: cyclophosphamide , diabetes mellitus, type 1 , insulin , magnetic resonance imaging , mice

Diabetes December 2012, Vol.62, 44-48. doi:https://doi.org/10.2337/db12-0153

Metabolism

Plasma Levels of Fetuin-A and Hepatic Enzymes and Risk of Type 2 Diabetes in Women in the U.S.

Qi Sun; Marilyn C. Cornelis; JoAnn E. Manson; Frank B. Hu

Abstract

View articletitled, Plasma Levels of Fetuin-A and Hepatic Enzymes and Risk of Type 2 Diabetes in Women in the U.S.

Supplementary data

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Topics: alpha-fetoproteins , diabetes mellitus, type 2 , liver enzyme , plasma

Diabetes December 2012, Vol.62, 49-55. doi:https://doi.org/10.2337/db12-0372

Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

Sebastian Beck Jorgensen; Hayley M. O’Neill; Lykke Sylow; Jane Honeyman; Kimberly A. Hewitt; Rengasamy Palanivel; Morgan D. Fullerton; Lisa Öberg; Anudharan Balendran; Sandra Galic; Chris van der Poel; Ian A. Trounce; Gordon S. Lynch; Jonathan D. Schertzer; Gregory R. Steinberg

Abstract

View articletitled, Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

Supplementary data

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Topics: mice , obesity , skeletal muscles , suppressor of cytokine signaling 3 protein

Diabetes December 2012, Vol.62, 56-64. doi:https://doi.org/10.2337/db12-0443

Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin

Stephanie R. Thorn; Laura D. Brown; Paul J. Rozance; William W. Hay, Jr.; Jacob E. Friedman

Abstract

View articletitled, Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin

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Topics: fetal growth retardation , fetus , glucose , insulin , liver

Diabetes December 2012, Vol.62, 65-73. doi:https://doi.org/10.2337/db11-1727

Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog

Christopher J. Ramnanan; Guillaume Kraft; Marta S. Smith; Ben Farmer; Doss Neal; Phillip E. Williams; Margaret Lautz; Tiffany Farmer; E. Patrick Donahue; Alan D. Cherrington; Dale S. Edgerton

Abstracts

View articletitled, Interaction Between the Central and Peripheral Effects of Insulin in Controlling Hepatic Glucose Metabolism in the Conscious Dog

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Topics: brain , insulin , liver , hypothalamus , hyperinsulinism

Diabetes December 2012, Vol.62, 74-84. doi:https://doi.org/10.2337/db12-0148

PGC-1α Improves Glucose Homeostasis in Skeletal Muscle in an Activity-Dependent Manner

Serge Summermatter; Guanghou Shui; Daniela Maag; Gesa Santos; Markus R. Wenk; Christoph Handschin

Abstracts

View articletitled, PGC-1α Improves Glucose Homeostasis in Skeletal Muscle in an Activity-Dependent Manner

Supplementary data

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Topics: diet, high-fat , glucose , glucose homeostasis , glucose uptake , insulin

Diabetes December 2012, Vol.62, 85-95. doi:https://doi.org/10.2337/db12-0291

Liver Glycogen Loading Dampens Glycogen Synthesis Seen in Response to Either Hyperinsulinemia or Intraportal Glucose Infusion

Jason J. Winnick; Zhibo An; Guillaume Kraft; Christopher J. Ramnanan; Jose M. Irimia; Marta Smith; Margaret Lautz; Peter J. Roach; Alan D. Cherrington

Abstract

View articletitled, Liver Glycogen Loading Dampens Glycogen Synthesis Seen in Response to Either Hyperinsulinemia or Intraportal Glucose Infusion

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Topics: glucose , glycogen synthesis , hyperinsulinism , infusion procedures , liver glycogen

Diabetes December 2012, Vol.62, 96-101. doi:https://doi.org/10.2337/db11-1773

Signal Transduction

Central Resistin Overexposure Induces Insulin Resistance Through Toll-Like Receptor 4

Yacir Benomar; Arieh Gertler; Pamela De Lacy; Delphine Crépin; Hassina Ould Hamouda; Laure Riffault; Mohammed Taouis

Abstract

View articletitled, Central Resistin Overexposure Induces Insulin Resistance Through Toll-Like Receptor 4

Supplementary data

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Topics: resistin , toll-like receptor 4 , insulin

Diabetes December 2012, Vol.62, 102-114. doi:https://doi.org/10.2337/db12-0237

Obesity Studies

Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Satomi Yogosawa; Shin Mizutani; Yoshihiro Ogawa; Tetsuro Izumi

Abstract

View articletitled, Activin Receptor-Like Kinase 7 Suppresses Lipolysis to Accumulate Fat in Obesity Through Downregulation of Peroxisome Proliferator–Activated Receptor γ and C/EBPα

Supplementary data

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Topics: adipocytes , lipase , lipolysis , mice , obesity

Diabetes December 2012, Vol.62, 115-123. doi:https://doi.org/10.2337/db12-0295

Autocrine Function of Aldehyde Dehydrogenase 1 as a Determinant of Diet- and Sex-Specific Differences in Visceral Adiposity

Rumana Yasmeen; Barbara Reichert; Jeffrey Deiuliis; Fangping Yang; Alisha Lynch; Joseph Meyers; Molly Sharlach; Sangsu Shin; Katharina S. Volz; Kari B. Green; Kichoon Lee; Hansjuerg Alder; Gregg Duester; Rudolf Zechner; Sanjay Rajagopalan; Ouliana Ziouzenkova

Abstracts

View articletitled, Autocrine Function of Aldehyde Dehydrogenase 1 as a Determinant of Diet- and Sex-Specific Differences in Visceral Adiposity

Supplementary data

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Topics: aldehyde dehydrogenase 1 , diet , enzymes , heart failure , mice

Diabetes December 2012, Vol.62, 124-136. doi:https://doi.org/10.2337/db11-1779

Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei

Patrícia O. Prada; Paula G.F. Quaresma; Andrea M. Caricilli; Andressa C. Santos; Dioze Guadagnini; Joseane Morari; Laís Weissmann; Eduardo R. Ropelle; José Barreto C. Carvalheira; Lício A. Velloso; Mario J.A. Saad

Abstract

View articletitled, Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei

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Topics: hypothalamic nucleus , insulin , leptin , mice , hypothalamus

Diabetes December 2012, Vol.62, 137-148. doi:https://doi.org/10.2337/db11-1388

A Potential Role for Dendritic Cell/Macrophage-Expressing DPP4 in Obesity-Induced Visceral Inflammation

Jixin Zhong; Xiaoquan Rao; Jeffrey Deiuliis; Zachary Braunstein; Vimal Narula; Jeffrey Hazey; Dean Mikami; Bradley Needleman; Abhay R. Satoskar; Sanjay Rajagopalan

Abstract

View articletitled, A Potential Role for Dendritic Cell/Macrophage-Expressing DPP4 in Obesity-Induced Visceral Inflammation

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Topics: inflammation , macrophages , obesity , t-lymphocytes , mice

Diabetes December 2012, Vol.62, 149-157. doi:https://doi.org/10.2337/db12-0230

Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis

Sana Basseri; Šárka Lhoták; Morgan D. Fullerton; Rengasamy Palanivel; Hua Jiang; Edward G. Lynn; Rebecca J. Ford; Kenneth N. Maclean; Gregory R. Steinberg; Richard C. Austin

Abstract

View articletitled, Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis

Supplementary data

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Topics: fatty liver , lipogenesis , mice , obesity , lipids

Diabetes December 2012, Vol.62, 158-169. doi:https://doi.org/10.2337/db12-0256

Islet Studies

Bcl-2 and Bcl-x_L Suppress Glucose Signaling in Pancreatic β-Cells

Dan S. Luciani; Sarah A. White; Scott B. Widenmaier; Varun V. Saran; Farnaz Taghizadeh; Xiaoke Hu; Michael F. Allard; James D. Johnson

Abstracts

View articletitled, Bcl-2 and Bcl-xL Suppress Glucose Signaling in Pancreatic β-Cells

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Topics: bcl2 gene , glucose , mice , mitochondria , insulin secretion

Diabetes December 2012, Vol.62, 170-182. doi:https://doi.org/10.2337/db11-1464

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Wendy M. McKimpson; Jeremy Weinberger; Lech Czerski; Min Zheng; Michael T. Crow; Jeffrey E. Pessin; Streamson C. Chua, Jr.; Richard N. Kitsis

Abstract

View articletitled, The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

Supplementary data

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Topics: apoptosis , apoptosis inhibitor , cell death , cyclophosphamide, doxorubicin, prednisone, and vincristine , diabetes mellitus, type 2

Diabetes December 2012, Vol.62, 183-193. doi:https://doi.org/10.2337/db12-0504

Immunology and Transplantation

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hye-Mi Lee; Jwa-Jin Kim; Hyun Jin Kim; Minho Shong; Bon Jeong Ku; Eun-Kyeong Jo

Abstracts

View articletitled, Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

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Topics: caspase-1 , diabetes mellitus, type 2 , inflammasomes , interleukin-18 , metformin

Diabetes December 2012, Vol.62, 194-204. doi:https://doi.org/10.2337/db12-0420

Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

Robin R. Knight; Deborah Kronenberg; Min Zhao; Guo Cai Huang; Martin Eichmann; Anna Bulek; Linda Wooldridge; David K. Cole; Andrew K. Sewell; Mark Peakman; Ania Skowera

Abstracts

View articletitled, Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

Supplementary data

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Topics: clone cells , cytotoxicity , killing , peptides , proton pump inhibitors

Diabetes December 2012, Vol.62, 205-213. doi:https://doi.org/10.2337/db12-0315

The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes

Karen T. Elvers; Ivey Geoghegan; Debbie K. Shoemark; Vito Lampasona; Polly J. Bingley; Alistair J.K. Williams

Abstract

View articletitled, The Core Cysteines, (C909) of Islet Antigen-2 and (C945) of Islet Antigen-2β, Are Crucial to Autoantibody Binding in Type 1 Diabetes

Supplementary data

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Topics: alanine , antibodies , autoantibodies , cysteine , diabetes mellitus, type 1

Diabetes December 2012, Vol.62, 214-222. doi:https://doi.org/10.2337/db11-1590

Pathophysiology

Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice

Masao Takeda; Koichi Yamamoto; Yukihiro Takemura; Hikari Takeshita; Kazuhiro Hongyo; Tatsuo Kawai; Hiroko Hanasaki-Yamamoto; Ryosuke Oguro; Yoichi Takami; Yuji Tatara; Yasushi Takeya; Ken Sugimoto; Kei Kamide; Mitsuru Ohishi; Hiromi Rakugi

Abstract

View articletitled, Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice

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Topics: angiotensin i , angiotensin ii , calories , diet , insulin

Diabetes December 2012, Vol.62, 223-233. doi:https://doi.org/10.2337/db12-0177

Hyperglycemia Slows Embryonic Growth and Suppresses Cell Cycle via Cyclin D1 and p21

Devon E. Scott-Drechsel; Sandra Rugonyi; Daniel L. Marks; Kent L. Thornburg; Monica T. Hinds

Abstracts

View articletitled, Hyperglycemia Slows Embryonic Growth and Suppresses Cell Cycle via Cyclin D1 and p21

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Topics: cell cycle , cyclin d1 , embryo , glucose , hyperglycemia

Diabetes December 2012, Vol.62, 234-242. doi:https://doi.org/10.2337/db12-0161

Complications

C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

Mahendra Prasad Bhatt; Young-Cheol Lim; JongYun Hwang; SungHun Na; Young-Myeong Kim; Kwon-Soo Ha

Abstracts

View articletitled, C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation

Supplementary data

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Topics: c-peptide , glucose , hyperglycemia , apoptosis , mice

Diabetes December 2012, Vol.62, 243-253. doi:https://doi.org/10.2337/db12-0293

Corneal Confocal Microscopy Detects Early Nerve Regeneration in Diabetic Neuropathy After Simultaneous Pancreas and Kidney Transplantation

Mitra Tavakoli; Maria Mitu-Pretorian; Ioannis N. Petropoulos; Hassan Fadavi; Omar Asghar; Uazman Alam; Georgios Ponirakis; Maria Jeziorska; Andy Marshall; Nathan Efron; Andrew J. Boulton; Titus Augustine; Rayaz A. Malik

Abstracts

View articletitled, Corneal Confocal Microscopy Detects Early Nerve Regeneration in Diabetic Neuropathy After Simultaneous Pancreas and Kidney Transplantation

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Topics: cornea , diabetic neuropathies , microscopy, confocal , neuropathy , renal and pancreas transplantation

Diabetes December 2012, Vol.62, 254-260. doi:https://doi.org/10.2337/db12-0574

Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models

Ying Chen; Yang Hu; Mingkai Lin; Alicia J. Jenkins; Anthony C. Keech; Robert Mott; Timothy J. Lyons; Jian-xing Ma

Abstracts

View articletitled, Therapeutic Effects of PPARα Agonists on Diabetic Retinopathy in Type 1 Diabetes Models

Supplementary data

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Topics: fenofibrate , rats , diabetes mellitus, type 1 , ppar alpha

Diabetes December 2012, Vol.62, 261-272. doi:https://doi.org/10.2337/db11-0413

Per2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow

Ashay D. Bhatwadekar; Yuanqing Yan; Xiaoping Qi; Jeffrey S. Thinschmidt; Matthew B. Neu; Sergio Li Calzi; Lynn C. Shaw; James M. Dominiguez; Julia V. Busik; Choogon Lee; Michael E. Boulton; Maria B. Grant

Abstracts

View articletitled, Per2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow

Supplementary data

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Topics: bone marrow , mice , retina , nitric oxide synthase

Diabetes December 2012, Vol.62, 273-282. doi:https://doi.org/10.2337/db12-0172

Pharmacology and Therapeutics

Activation of Enteroendocrine Membrane Progesterone Receptors Promotes Incretin Secretion and Improves Glucose Tolerance in Mice

Grace B. Flock; Xiemin Cao; Marlena Maziarz; Daniel J. Drucker

Abstract

View articletitled, Activation of Enteroendocrine Membrane Progesterone Receptors Promotes Incretin Secretion and Improves Glucose Tolerance in Mice

Supplementary data

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Topics: bodily secretions , glucagon-like peptide 1 , glucose , glucose tolerance , incretin

Diabetes December 2012, Vol.62, 283-290. doi:https://doi.org/10.2337/db12-0601

Genetics / Genomes / Proteomics / Metabolomics

A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans

Abstracts

View articletitled, A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans

Supplementary data

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Topics: diabetes mellitus, type 2 , grk5 gene , single nucleotide polymorphism , genome-wide association study

Diabetes December 2012, Vol.62, 291-298. doi:https://doi.org/10.2337/db12-0454

Identification of Cross-Species Shared Transcriptional Networks of Diabetic Nephropathy in Human and Mouse Glomeruli

Jeffrey B. Hodgin; Viji Nair; Hongyu Zhang; Ann Randolph; Raymond C. Harris; Robert G. Nelson; E. Jennifer Weil; James D. Cavalcoli; Jignesh M. Patel; Frank C. Brosius, III; Matthias Kretzler

Abstracts

View articletitled, Identification of Cross-Species Shared Transcriptional Networks of Diabetic Nephropathy in Human and Mouse Glomeruli

Supplementary data

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Topics: genes , kidney glomerulus , mice , transcription, genetic , diabetic nephropathy

Diabetes December 2012, Vol.62, 299-308. doi:https://doi.org/10.2337/db11-1667

Statement of Retraction

Blockade of receptor for advanced glycation end products in a model of type 1 diabetic leukoencephalopathy. Diabetes. 19 November 2012 [Epub ahead of print]

N Rincon; K Xu; J Li; JA Martinez; GS Singh; D Han; P Lalli; A Ayer; K Tse; L Rong; AM Schmidt; CC Toth

Extract

View articletitled, Blockade of receptor for advanced glycation end products in a model of type 1 diabetic leukoencephalopathy. Diabetes. 19 November 2012 [Epub ahead of print]

Supplementary data

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Topics: leukoencephalopathies , receptor for advanced glycation endproducts

Diabetes December 2012, Vol.62, 309. doi:https://doi.org/10.2337/db12-0317

Issues and Events

Extract

View articletitled, Issues and Events

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Topics: chief complaint , colorado , metabolic syndrome x , prehypertension , wisconsin

Diabetes December 2012, Vol.62, 310. doi:https://doi.org/10.2337/db13-ie01

Diabetes Digests

Highlights From the Latest in Diabetes Research

Extract

View articletitled, Highlights From the Latest in Diabetes Research

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Topics: alpha-fetoproteins , atherosclerosis , calorie restricted diet , diabetes mellitus, type 2 , endothelium

Diabetes December 2012, Vol.62, 311-312. doi:https://doi.org/10.2337/db12-dd01

Online Letters to the Editor

Comment on: Straznicky et al. Neuroadrenergic Dysfunction Along the Diabetes Continuum: A Comparative Study in Obese Metabolic Syndrome Subjects. Diabetes 2012;61:2506–2516

Simona Frontoni

Extract

View articletitled, Comment on: Straznicky et al. Neuroadrenergic Dysfunction Along the Diabetes Continuum: A Comparative Study in Obese Metabolic Syndrome Subjects. Diabetes 2012;61:2506–2516

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Topics: metabolic syndrome x , obesity

Diabetes December 2012, Vol.62, e1. doi:https://doi.org/10.2337/db12-1087

Response to Comment on: Straznicky et al. Neuroadrenergic Dysfunction Along the Diabetes Continuum: A Comparative Study in Obese Metabolic Syndrome Subjects. Diabetes 2012;61:2506–2516

Nora E. Straznicky; Elisabeth A. Lambert; Gavin W. Lambert

Extract

View articletitled, Response to Comment on: Straznicky et al. Neuroadrenergic Dysfunction Along the Diabetes Continuum: A Comparative Study in Obese Metabolic Syndrome Subjects. Diabetes 2012;61:2506–2516

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Topics: metabolic syndrome x , obesity

Diabetes December 2012, Vol.62, e2. doi:https://doi.org/10.2337/db12-1211

Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801–1813

Xiaodan Lu; Yaowu Zheng

Extract

View articletitled, Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801–1813

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Topics: adipose tissue , diet , insulin resistance , obesity , protein overexpression

Diabetes December 2012, Vol.62, e3. doi:https://doi.org/10.2337/db12-1130

Response to Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801–1813

Ivet Elias; Sylvie Franckhauser; Fatima Bosch

Extract

View articletitled, Response to Comment on: Elias et al. Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes 2012;61:1801–1813

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Topics: adipose tissue , diet , insulin resistance , obesity , protein overexpression

Diabetes December 2012, Vol.62, e4. doi:https://doi.org/10.2337/db12-1274

Issues

Cover Image

Perspectives in Diabetes

Commentary

Technological Advances

Metabolism

Signal Transduction

Obesity Studies

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Pharmacology and Therapeutics

Genetics / Genomes / Proteomics / Metabolomics

Statement of Retraction

Issues and Events

Diabetes Digests

Online Letters to the Editor

Email alerts

RSS Feeds

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