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Volume 62, Issue 12
1 December 2013
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ISSN 0012-1797
EISSN 1939-327X
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In This Issue

In This Issue of Diabetes
View articletitled, In This Issue of <em>Diabetes</em>
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Diabetes November 2013, Vol.62, 3961-3962. doi:https://doi.org/10.2337/db13-ti12

Perspectives in Diabetes

Celebrating 30 Years of Research Accomplishments of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study
Judith E. Fradkin; Catherine C. Cowie; Mary C. Hanlon; Griffin P. Rodgers
View articletitled, Celebrating 30 Years of Research Accomplishments of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study
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Diabetes November 2013, Vol.62, 3963-3967. doi:https://doi.org/10.2337/db13-1108
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Advances and Contributions
David M. Nathan; Margaret Bayless; Patricia Cleary; Saul Genuth; Rose Gubitosi-Klug; John M. Lachin; Gayle Lorenzi; Bernard Zinman; for the DCCT/EDIC Research Group
View articletitled, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Advances and Contributions
Supplementary data
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Diabetes November 2013, Vol.62, 3976-3986. doi:https://doi.org/10.2337/db13-1093

Original Article

Perspectives in Diabetes
An Update on the Molecular Actions of Fenofibrate and Its Clinical Effects on Diabetic Retinopathy and Other Microvascular End Points in Patients With Diabetes
Jonathan E. Noonan; Alicia J. Jenkins; Jian-Xing Ma; Anthony C. Keech; Jie Jin Wang; Ecosse L. Lamoureux
View articletitled, An Update on the Molecular Actions of Fenofibrate and Its Clinical Effects on Diabetic Retinopathy and Other Microvascular End Points in Patients With Diabetes
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Diabetes November 2013, Vol.62, 3968-3975. doi:https://doi.org/10.2337/db13-0800

Commentaries

Soaping Up Type 2 Diabetes With Bile Acids?: The Link Between Glucose and Bile Acid Metabolism in Humans Tightens: Quality Matters!
Bart Staels; Janne Prawitt
View articletitled, Soaping Up Type 2 Diabetes With Bile Acids?<span class="subtitle-colon">: </span><span class="subtitle">The Link Between Glucose and Bile Acid Metabolism in Humans Tightens: Quality Matters!</span>
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Diabetes November 2013, Vol.62, 3987-3989. doi:https://doi.org/10.2337/db13-1278
Following the Fate of the Failing β-Cell: New Insights From First-Phase Insulin Responses
Alistair J.K. Williams; Anna E. Long
View articletitled, Following the Fate of the Failing β-Cell: New Insights From First-Phase Insulin Responses
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Diabetes November 2013, Vol.62, 3990-3992. doi:https://doi.org/10.2337/db13-1314
Antagonizing Wnt Pathway in Diabetic Retinopathy
Ling Zhao; Sherrina H. Patel; Jacqueline Pei; Kang Zhang
View articletitled, Antagonizing Wnt Pathway in Diabetic Retinopathy
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Diabetes November 2013, Vol.62, 3993-3995. doi:https://doi.org/10.2337/db13-1309
New Insights Into Metabolic Regulation via Bifurcated Function of Estrogen Receptor α
Tsutomu Wada; Hiroshi Tsuneki; Toshiyasu Sasaoka
View articletitled, New Insights Into Metabolic Regulation via Bifurcated Function of Estrogen Receptor α
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Diabetes November 2013, Vol.62, 3996-3998. doi:https://doi.org/10.2337/db13-1325
Lactate and the Mechanism of Hypoglycemia-Associated Autonomic Failure in Diabetes
Ana María Arbeláez; Philip E. Cryer
View articletitled, Lactate and the Mechanism of Hypoglycemia-Associated Autonomic Failure in Diabetes
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Diabetes November 2013, Vol.62, 3999-4001. doi:https://doi.org/10.2337/db13-1360
STAT4: An Initiator of Meta-Inflammation in Adipose Tissue?
Nelson H. Knudsen; Chih-Hao Lee
View articletitled, STAT4: An Initiator of Meta-Inflammation in Adipose Tissue?
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Diabetes November 2013, Vol.62, 4002-4003. doi:https://doi.org/10.2337/db13-1416
Vascularization of the Pancreas: An Evolving Role From Embryogenesis to Adulthood
Bertrand Duvillié
View articletitled, Vascularization of the Pancreas: An Evolving Role From Embryogenesis to Adulthood
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Diabetes November 2013, Vol.62, 4004-4005. doi:https://doi.org/10.2337/db13-1421
The Vascular Endothelium, a Benign Restrictive Barrier? NO! Role of Nitric Oxide in Regulating Insulin Action
Joyce M. Richey
View articletitled, The Vascular Endothelium, a Benign Restrictive Barrier? NO! Role of Nitric Oxide in Regulating Insulin Action
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Diabetes November 2013, Vol.62, 4006-4008. doi:https://doi.org/10.2337/db13-1395
Islet Autoantibody Testing: An End to the Trials and Tribulations?
Polly J. Bingley; Alistair J.K. Williams
View articletitled, Islet Autoantibody Testing: An End to the Trials and Tribulations?
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Diabetes November 2013, Vol.62, 4009-4011. doi:https://doi.org/10.2337/db13-1445

Original Research

Technological Advances
In Vivo Adeno-Associated Viral Vector–Mediated Genetic Engineering of White and Brown Adipose Tissue in Adult Mice
Veronica Jimenez; Sergio Muñoz; Estefania Casana; Cristina Mallol; Ivet Elias; Claudia Jambrina; Albert Ribera; Tura Ferre; Sylvie Franckhauser; Fatima Bosch
View articletitled, In Vivo Adeno-Associated Viral Vector–Mediated Genetic Engineering of White and Brown Adipose Tissue in Adult Mice
Supplementary data
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Diabetes November 2013, Vol.62, 4012-4022. doi:https://doi.org/10.2337/db13-0311
Metabolism
Direct Effects of TNF-α on Local Fuel Metabolism and Cytokine Levels in the Placebo-Controlled, Bilaterally Infused Human Leg: Increased Insulin Sensitivity, Increased Net Protein Breakdown, and Increased IL-6 Release
Ermina Bach; Roni R. Nielsen; Mikkel H. Vendelbo; Andreas B. Møller; Niels Jessen; Mads Buhl; Thomas K- Hafstrøm; Lars Holm; Steen B. Pedersen; Henriette Pilegaard; Rasmus S. Biensø; Jens O.L. Jørgensen; Niels Møller
View articletitled, Direct Effects of TNF-α on Local Fuel Metabolism and Cytokine Levels in the Placebo-Controlled, Bilaterally Infused Human Leg<span class="subtitle-colon">: </span><span class="subtitle">Increased Insulin Sensitivity, Increased Net Protein Breakdown, and Increased IL-6 Release</span>
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Diabetes November 2013, Vol.62, 4023-4029. doi:https://doi.org/10.2337/db13-0138
Nitric Oxide Directly Promotes Vascular Endothelial Insulin Transport
Hong Wang; Aileen X. Wang; Kevin Aylor; Eugene J. Barrett
View articletitled, Nitric Oxide Directly Promotes Vascular Endothelial Insulin Transport
Supplementary data
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Diabetes November 2013, Vol.62, 4030-4042. doi:https://doi.org/10.2337/db13-0627
Lower “Awake and Fed Thermogenesis” Predicts Future Weight Gain in Subjects With Abdominal Adiposity
Paolo Piaggi; Jonathan Krakoff; Clifton Bogardus; Marie S. Thearle
View articletitled, Lower “Awake and Fed Thermogenesis” Predicts Future Weight Gain in Subjects With Abdominal Adiposity
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Diabetes November 2013, Vol.62, 4043-4051. doi:https://doi.org/10.2337/db13-0785
Hepatic Notch Signaling Correlates With Insulin Resistance and Nonalcoholic Fatty Liver Disease
Luca Valenti; Rosa M. Mendoza; Raffaela Rametta; Marco Maggioni; Chris Kitajewski; Carrie J. Shawber; Utpal B. Pajvani
View articletitled, Hepatic Notch Signaling Correlates With Insulin Resistance and Nonalcoholic Fatty Liver Disease
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Diabetes November 2013, Vol.62, 4052-4062. doi:https://doi.org/10.2337/db13-0769
Prandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol
Fariba Shojaee-Moradie; Yuying Ma; Shaoying Lou; Roman Hovorka; A. Margot Umpleby
View articletitled, Prandial Hypertriglyceridemia in Metabolic Syndrome Is Due to an Overproduction of Both Chylomicron and VLDL Triacylglycerol
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Diabetes November 2013, Vol.62, 4063-4069. doi:https://doi.org/10.2337/db13-0935
Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Alexander von Wilamowitz-Moellendorff; Roger W. Hunter; Mar García-Rocha; Li Kang; Iliana López-Soldado; Louise Lantier; Kashyap Patel; Mark W. Peggie; Carlos Martínez-Pons; Martin Voss; Joaquim Calbó; Patricia T.W. Cohen; David H. Wasserman; Joan J. Guinovart; Kei Sakamoto
View articletitled, Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Supplementary data
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Diabetes November 2013, Vol.62, 4070-4082. doi:https://doi.org/10.2337/db13-0880
Time Lag of Glucose From Intravascular to Interstitial Compartment in Humans
Ananda Basu; Simmi Dube; Michael Slama; Isabel Errazuriz; Jose Carlos Amezcua; Yogish C. Kudva; Thomas Peyser; Rickey E. Carter; Claudio Cobelli; Rita Basu
View articletitled, Time Lag of Glucose From Intravascular to Interstitial Compartment in Humans
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Diabetes November 2013, Vol.62, 4083-4087. doi:https://doi.org/10.2337/db13-1132
Signal Transduction
Gestational Diabetes Mellitus Impairs Nrf2-Mediated Adaptive Antioxidant Defenses and Redox Signaling in Fetal Endothelial Cells In Utero
Xinghua Cheng; Sarah J. Chapple; Bijal Patel; William Puszyk; David Sugden; Xiaoke Yin; Manuel Mayr; Richard C.M. Siow; Giovanni E. Mann
View articletitled, Gestational Diabetes Mellitus Impairs Nrf2-Mediated Adaptive Antioxidant Defenses and Redox Signaling in Fetal Endothelial Cells In Utero
Supplementary data
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Diabetes November 2013, Vol.62, 4088-4097. doi:https://doi.org/10.2337/db13-0169
Obesity Studies
Prevention of Obesity and Insulin Resistance by Estrogens Requires ERα Activation Function-2 (ERαAF-2), Whereas ERαAF-1 Is Dispensable
Sandra Handgraaf; Elodie Riant; Aurélie Fabre; Aurélie Waget; Rémy Burcelin; Philippe Lière; Andrée Krust; Pierre Chambon; Jean-François Arnal; Pierre Gourdy
View articletitled, Prevention of Obesity and Insulin Resistance by Estrogens Requires ERα Activation Function-2 (ERαAF-2), Whereas ERαAF-1 Is Dispensable
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Diabetes November 2013, Vol.62, 4098-4108. doi:https://doi.org/10.2337/db13-0282
STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation
Anca D. Dobrian; Elena V. Galkina; Qian Ma; Margaret Hatcher; Sabai Myo Aye; Mathew J. Butcher; Kaiwen Ma; Bronson A. Haynes; Mark H. Kaplan; Jerry L. Nadler
View articletitled, STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation
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Diabetes November 2013, Vol.62, 4109-4121. doi:https://doi.org/10.2337/db12-1275
PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders
Li Wang; Ruifeng Teng; Lijun Di; Heather Rogers; Hong Wu; Jeffrey B. Kopp; Constance Tom Noguchi
View articletitled, PPARα and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders
Supplementary data
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Diabetes November 2013, Vol.62, 4122-4131. doi:https://doi.org/10.2337/db13-0518
Programmed Cell Death-4 Deficiency Prevents Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance
Qun Wang; Zhaojing Dong; Xianglan Liu; Xingguo Song; Qiang Song; Qianwen Shang; Yang Jiang; Chun Guo; Lining Zhang
View articletitled, Programmed Cell Death-4 Deficiency Prevents Diet-Induced Obesity, Adipose Tissue Inflammation, and Insulin Resistance
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Diabetes November 2013, Vol.62, 4132-4143. doi:https://doi.org/10.2337/db13-0097
Islet Studies
Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis
Chunhua Dai; Marcela Brissova; Rachel B. Reinert; Lara Nyman; Eric H. Liu; Courtney Thompson; Alena Shostak; Masakazu Shiota; Takamune Takahashi; Alvin C. Powers
View articletitled, Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis
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Diabetes November 2013, Vol.62, 4144-4153. doi:https://doi.org/10.2337/db12-1657
Vascular Endothelial Growth Factor-A and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets
Rachel B. Reinert; Marcela Brissova; Alena Shostak; Fong Cheng Pan; Greg Poffenberger; Qing Cai; Gregory L. Hundemer; Jeannelle Kantz; Courtney S. Thompson; Chunhua Dai; Owen P. McGuinness; Alvin C. Powers
View articletitled, Vascular Endothelial Growth Factor-A and Islet Vascularization Are Necessary in Developing, but Not Adult, Pancreatic Islets
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Diabetes November 2013, Vol.62, 4154-4164. doi:https://doi.org/10.2337/db13-0071
Conditional Hypovascularization and Hypoxia in Islets Do Not Overtly Influence Adult β-Cell Mass or Function
Joke D'Hoker; Nico De Leu; Yves Heremans; Luc Baeyens; Kohtaro Minami; Cai Ying; Astrid Lavens; Marie Chintinne; Geert Stangé; Judith Magenheim; Avital Swisa; Geert Martens; Daniel Pipeleers; Mark van de Casteele; Susumo Seino; Eli Keshet; Yuval Dor; Harry Heimberg
View articletitled, Conditional Hypovascularization and Hypoxia in Islets Do Not Overtly Influence Adult β-Cell Mass or Function
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Diabetes November 2013, Vol.62, 4165-4173. doi:https://doi.org/10.2337/db12-1827
Immunology and Transplantation
GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes
Dongmei Miao; K. Michelle Guyer; Fran Dong; Ling Jiang; Andrea K. Steck; Marian Rewers; George S. Eisenbarth; Liping Yu
View articletitled, GAD65 Autoantibodies Detected by Electrochemiluminescence Assay Identify High Risk for Type 1 Diabetes
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Diabetes November 2013, Vol.62, 4174-4178. doi:https://doi.org/10.2337/db13-0534
Pathophysiology
Acceleration of the Loss of the First-Phase Insulin Response During the Progression to Type 1 Diabetes in Diabetes Prevention Trial–Type 1 Participants
Jay M. Sosenko; Jay S. Skyler; Craig A. Beam; Jeffrey P. Krischer; Carla J. Greenbaum; Jeffrey Mahon; Lisa E. Rafkin; Della Matheson; Kevan C. Herold; Jerry P. Palmer; and the Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups
View articletitled, Acceleration of the Loss of the First-Phase Insulin Response During the Progression to Type 1 Diabetes in Diabetes Prevention Trial–Type 1 Participants
Supplementary data
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Diabetes November 2013, Vol.62, 4179-4183. doi:https://doi.org/10.2337/db13-0656
Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids
Rebecca A. Haeusler; Brenno Astiarraga; Stefania Camastra; Domenico Accili; Ele Ferrannini
View articletitled, Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids
Supplementary data
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Diabetes November 2013, Vol.62, 4184-4191. doi:https://doi.org/10.2337/db13-0639
TRIB3 Mediates Glucose-Induced Insulin Resistance via a Mechanism That Requires the Hexosamine Biosynthetic Pathway
Wei Zhang; Jiarong Liu; Ling Tian; Qinglan Liu; Yuchang Fu; W. Timothy Garvey
View articletitled, TRIB3 Mediates Glucose-Induced Insulin Resistance via a Mechanism That Requires the Hexosamine Biosynthetic Pathway
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Diabetes November 2013, Vol.62, 4192-4200. doi:https://doi.org/10.2337/db13-0312
Genetic Disruption of SOD1 Gene Causes Glucose Intolerance and Impairs β-Cell Function
Giovanna Muscogiuri; Adam B. Salmon; Cristina Aguayo-Mazzucato; Mengyao Li; Bogdan Balas; Rodolfo Guardado-Mendoza; Andrea Giaccari; Robert L. Reddick; Sara M. Reyna; Gordon Weir; Ralph A. DeFronzo; Holly Van Remmen; Nicolas Musi
View articletitled, Genetic Disruption of SOD1 Gene Causes Glucose Intolerance and Impairs β-Cell Function
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Diabetes November 2013, Vol.62, 4201-4207. doi:https://doi.org/10.2337/db13-0314
Diminished Adenosine A1 Receptor Expression in Pancreatic α-Cells May Contribute to the Pathology of Type 1 Diabetes
Linda Yip; Cariel Taylor; Chan C. Whiting; C. Garrison Fathman
View articletitled, Diminished Adenosine A1 Receptor Expression in Pancreatic α-Cells May Contribute to the Pathology of Type 1 Diabetes
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Diabetes November 2013, Vol.62, 4208-4219. doi:https://doi.org/10.2337/db13-0614
Complications
Effects of a Single Bout of Interval Hypoxia on Cardiorespiratory Control in Patients With Type 1 Diabetes
Tobias Duennwald; Luciano Bernardi; Daniel Gordin; Anna Sandelin; Anna Syreeni; Christopher Fogarty; Janne P. Kytö; Hannes Gatterer; Markku Lehto; Sohvi Hörkkö; Carol Forsblom; Martin Burtscher; Per-Henrik Groop; on behalf of the FinnDiane Study Group
View articletitled, Effects of a Single Bout of Interval Hypoxia on Cardiorespiratory Control in Patients With Type 1 Diabetes
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Diabetes November 2013, Vol.62, 4220-4227. doi:https://doi.org/10.2337/db13-0167
Antiangiogenic and Antineuroinflammatory Effects of Kallistatin Through Interactions With the Canonical Wnt Pathway
Xiaochen Liu; Bin Zhang; Jeffrey D. McBride; Kevin Zhou; Kyungwon Lee; Yueping Zhou; Zuguo Liu; Jian-xing Ma
View articletitled, Antiangiogenic and Antineuroinflammatory Effects of Kallistatin Through Interactions With the Canonical Wnt Pathway
Supplementary data
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Diabetes November 2013, Vol.62, 4228-4238. doi:https://doi.org/10.2337/db12-1710
Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes
Owen Chan; Sachin A. Paranjape; Adam Horblitt; Wanling Zhu; Robert S. Sherwin
View articletitled, Lactate-Induced Release of GABA in the Ventromedial Hypothalamus Contributes to Counterregulatory Failure in Recurrent Hypoglycemia and Diabetes
Supplementary data
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Diabetes November 2013, Vol.62, 4239-4246. doi:https://doi.org/10.2337/db13-0770
Peroxynitrite-Dependent Zinc Release and Inactivation of Guanosine 5′-Triphosphate Cyclohydrolase 1 Instigate Its Ubiquitination in Diabetes
Yu Zhao; Jiliang Wu; Huaiping Zhu; Ping Song; Ming-Hui Zou
View articletitled, Peroxynitrite-Dependent Zinc Release and Inactivation of Guanosine 5′-Triphosphate Cyclohydrolase 1 Instigate Its Ubiquitination in Diabetes
Supplementary data
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Diabetes November 2013, Vol.62, 4247-4256. doi:https://doi.org/10.2337/db13-0751
Increased Persistent Sodium Current Due to Decreased PI3K Signaling Contributes to QT Prolongation in the Diabetic Heart
Zhongju Lu; Ya-Ping Jiang; Chia-Yen C. Wu; Lisa M. Ballou; Shengnan Liu; Eileen S. Carpenter; Michael R. Rosen; Ira S. Cohen; Richard Z. Lin
View articletitled, Increased Persistent Sodium Current Due to Decreased PI3K Signaling Contributes to QT Prolongation in the Diabetic Heart
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Diabetes November 2013, Vol.62, 4257-4265. doi:https://doi.org/10.2337/db13-0420
Adipose Mesenchymal Stromal Cells Isolated From Type 2 Diabetic Patients Display Reduced Fibrinolytic Activity
Lourdes Acosta; Abdelkrim Hmadcha; Natalia Escacena; Inmaculada Pérez-Camacho; Antonio de la Cuesta; Rafael Ruiz-Salmeron; Benoit R. Gauthier; Bernat Soria
View articletitled, Adipose Mesenchymal Stromal Cells Isolated From Type 2 Diabetic Patients Display Reduced Fibrinolytic Activity
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Diabetes November 2013, Vol.62, 4266-4269. doi:https://doi.org/10.2337/db13-0896
Genetics / Genomes / Proteomics / Metabolomics
Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
Cristina Menni; Eric Fauman; Idil Erte; John R.B. Perry; Gabi Kastenmüller; So-Youn Shin; Ann-Kristin Petersen; Craig Hyde; Maria Psatha; Kirsten J. Ward; Wei Yuan; Mike Milburn; Colin N.A. Palmer; Timothy M. Frayling; Jeff Trimmer; Jordana T. Bell; Christian Gieger; Rob P. Mohney; Mary Julia Brosnan; Karsten Suhre; Nicole Soranzo; Tim D. Spector
View articletitled, Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
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Diabetes November 2013, Vol.62, 4270-4276. doi:https://doi.org/10.2337/db13-0570
Genetic Variation in CDH13 Is Associated With Lower Plasma Adiponectin Levels but Greater Adiponectin Sensitivity in East Asian Populations
He Gao; Yu-Mi Kim; Peng Chen; Michiya Igase; Ryuichi Kawamoto; Mi Kyung Kim; Katsuhiko Kohara; Jeannette Lee; Tetsuro Miki; Rick Twee-Hee Ong; Hiroshi Onuma; Haruhiko Osawa; Xueling Sim; Yik Ying Teo; Yasuharu Tabara; E Shyong Tai; Rob M. van Dam
View articletitled, Genetic Variation in <em>CDH13</em> Is Associated With Lower Plasma Adiponectin Levels but Greater Adiponectin Sensitivity in East Asian Populations
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Diabetes November 2013, Vol.62, 4277-4283. doi:https://doi.org/10.2337/db13-0129

Errata

Identification of metabolic modifiers that underlie phenotypic variations in energy-balance regulation. Diabetes 2011;60:726–734
CL Chang; JJ Cai; PJ Cheng; HY Chueh; SYT Hsu
View articletitled, Identification of metabolic modifiers that underlie phenotypic variations in energy-balance regulation. Diabetes 2011;60:726–734
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Diabetes November 2013, Vol.62, 4284. doi:https://doi.org/10.2337/db13-er12
Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects. Diabetes 2013;62:2752–2756
M Sathananthan; LP Farrugia; JM Miles; F Piccinini; C Dalla Man; AR Zinsmeister; C Cobelli; RA Rizza; A Vella
View articletitled, Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects. Diabetes 2013;62:2752–2756
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Diabetes November 2013, Vol.62, 4284. doi:https://doi.org/10.2337/db13-er12a

Issues and Events

Issues and Events
View articletitled, Issues and Events
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Diabetes November 2013, Vol.62, 4285. doi:https://doi.org/10.2337/db13-ie12

Diabetes Digests

Highlights From the Latest in Diabetes Research
View articletitled, Highlights From the Latest in Diabetes Research
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Diabetes November 2013, Vol.62, 4286-4287. doi:https://doi.org/10.2337/db13-dd12

Online Letters to the Editor

Comment on: Lazo et al. NH2-Terminal Pro–Brain Natriuretic Peptide and Risk of Diabetes. Diabetes 2013;62:3189–3193
Cedric Moro; Jens Jordan; Andreas L. Birkenfeld
View articletitled, Comment on: Lazo et al. NH<sub>2</sub>-Terminal Pro–Brain Natriuretic Peptide and Risk of Diabetes. Diabetes 2013;62:3189–3193
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Diabetes November 2013, Vol.62, e28. doi:https://doi.org/10.2337/db13-1034
Comment on: Sitnick et al. Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity. Diabetes 2013;62:3350–3361
Cedric Moro; Dominique Langin
View articletitled, Comment on: Sitnick et al. Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity. Diabetes 2013;62:3350–3361
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Diabetes November 2013, Vol.62, e29. doi:https://doi.org/10.2337/db13-1107
Comment on: Sukumar et al. Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction. Diabetes 2013;62:2130–2134
Karin A.M. Jandeleit-Dahm; Harald H.H.W. Schmidt
View articletitled, Comment on: Sukumar et al. Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction. Diabetes 2013;62:2130–2134
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Diabetes November 2013, Vol.62, e30. doi:https://doi.org/10.2337/db13-1286
Response to Comment on: Sukumar et al. Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction. Diabetes 2013;62:2130–2134
Piruthivi Sukumar; Mark T. Kearney
View articletitled, Response to Comment on: Sukumar et al. Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction. Diabetes 2013;62:2130–2134
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Diabetes November 2013, Vol.62, e31. doi:https://doi.org/10.2337/db13-1392
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
300-OR: Beneficial Effect of the Combination Therapy of Cagrilintide, a Dual Amylin/Calcitonin Agonist, and Tirzepatide, a Dual GLP-1/GIP Agonist, on Body Weight Loss in Obese Rats
Elevated First-Trimester Neutrophil Count Is Closely Associated With the Development of Maternal Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes
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