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In This Issue of Diabetes

Extract

View articletitled, In This Issue of Diabetes

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Topics: c-reactive protein , diabetes mellitus complications , diabetic neuropathies , endoplasmic reticulum , glucose

Diabetes February 2013, Vol.62, 667-668. doi:https://doi.org/10.2337/db13-ti03

Perspectives In Diabetes

Challenging the FDA Black Box Warning for High Aspirin Dose With Ticagrelor in Patients With Diabetes

James J. DiNicolantonio; Victor L. Serebruany

Abstracts

View articletitled, Challenging the FDA Black Box Warning for High Aspirin Dose With Ticagrelor in Patients With Diabetes

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Topics: ticagrelor , aspirin

Diabetes February 2013, Vol.62, 669-671. doi:https://doi.org/10.2337/db12-0746

Perspectives in Diabetes

Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging

Martin Picard; Doug M. Turnbull

Abstracts

View articletitled, Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging

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Topics: aging , chronic disease , dna, mitochondrial , mitochondria

Diabetes February 2013, Vol.62, 672-678. doi:https://doi.org/10.2337/db12-1203

Commentary

Diabetic Foot Ulcer Microbiome: One Small Step for Molecular Microbiology . . . One Giant Leap for Understanding Diabetic Foot Ulcers?

Benjamin A. Lipsky; Jean-Louis Richard; Jean-Philippe Lavigne

Abstracts

View articletitled, Diabetic Foot Ulcer Microbiome: One Small Step for Molecular Microbiology . . . One Giant Leap for Understanding Diabetic Foot Ulcers?

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Topics: diabetic foot ulcer , microbiology , microbiome

Diabetes February 2013, Vol.62, 679-681. doi:https://doi.org/10.2337/db12-1325

Metabolomics, Stable Isotopes, and A⁻β⁺ Ketosis-Prone Diabetes

Maria A. Ramos-Roman; Shawn C. Burgess; Jeffrey D. Browning

Abstracts

View articletitled, Metabolomics, Stable Isotopes, and A−β+ Ketosis-Prone Diabetes

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Topics: isotopes , ketosis , metabolomics

Diabetes February 2013, Vol.62, 682-684. doi:https://doi.org/10.2337/db12-1347

Improving Insulin Sensitivity With HDAC Inhibitor

Jianping Ye

Abstracts

View articletitled, Improving Insulin Sensitivity With HDAC Inhibitor

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Topics: histone deacetylase inhibitors , insulin sensitivity

Diabetes February 2013, Vol.62, 685-687. doi:https://doi.org/10.2337/db12-1354

Novel Link Between Inflammation, Endothelial Dysfunction, and Muscle Insulin Resistance

Franck Mauvais-Jarvis

Abstracts

View articletitled, Novel Link Between Inflammation, Endothelial Dysfunction, and Muscle Insulin Resistance

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Topics: endothelial dysfunction , inflammation , insulin resistance

Diabetes February 2013, Vol.62, 688-690. doi:https://doi.org/10.2337/db12-1434

Impact of ER Protein Homeostasis on Metabolism

Abdullah Yalcin; Gökhan S. Hotamisligil

Abstracts

View articletitled, Impact of ER Protein Homeostasis on Metabolism

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Topics: catabolism , emergency service, hospital , metabolism , obesity , proteostasis

Diabetes February 2013, Vol.62, 691-693. doi:https://doi.org/10.2337/db12-1526

MicroRNA-7 Control of β-Cell Replication

Juan Domínguez-Bendala; Dagmar Klein; Ricardo L. Pastori

Abstracts

View articletitled, MicroRNA-7 Control of β-Cell Replication

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Topics: micrornas , mtor serine-threonine kinases

Diabetes February 2013, Vol.62, 694-695. doi:https://doi.org/10.2337/db12-1518

Role of Endoplasmic Reticulum Stress in Diabetic Neuropathy

Norman E. Cameron

Abstracts

View articletitled, Role of Endoplasmic Reticulum Stress in Diabetic Neuropathy

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Topics: diabetic neuropathies , endoplasmic reticulum , stress , cyclophosphamide, doxorubicin, prednisone, and vincristine

Diabetes February 2013, Vol.62, 696-697. doi:https://doi.org/10.2337/db12-1469

Teaching an Old Drug New Tricks: Can Paroxetine Ease the Burden of Cardiovascular Disease in Diabetes?

Stephen B. Wheatcroft

Abstracts

View articletitled, Teaching an Old Drug New Tricks: Can Paroxetine Ease the Burden of Cardiovascular Disease in Diabetes?

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Topics: cardiovascular disease in diabetes , paroxetine , cardiovascular diseases , chronic venous disease , mitochondria

Diabetes February 2013, Vol.62, 698-700. doi:https://doi.org/10.2337/db12-1530

Insulin Resistance by Adiponectin Deficiency: Is the Action in Skeletal Muscle?

Fredrik Karpe

Abstracts

View articletitled, Insulin Resistance by Adiponectin Deficiency: Is the Action in Skeletal Muscle?

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Topics: adiponectin , insulin resistance , skeletal muscles

Diabetes February 2013, Vol.62, 701-702. doi:https://doi.org/10.2337/db12-1519

Blocking the Entrance to Open the Gate

Patrick Schrauwen; Silvie Timmers; Matthijs K.C. Hesselink

Abstracts

View articletitled, Blocking the Entrance to Open the Gate

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Topics: carnitine o-palmitoyltransferase , diabetes mellitus, type 2 , fatty acids , glucose , insulin

Diabetes February 2013, Vol.62, 703-705. doi:https://doi.org/10.2337/db12-1663

TCF7L2 and Glucose Metabolism: Time to Look Beyond the Pancreas

Marcelo A. Nobrega

Abstracts

View articletitled, TCF7L2 and Glucose Metabolism: Time to Look Beyond the Pancreas

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Topics: diabetes mellitus, type 2 , glucose metabolism , pancreas , tcf7l2 gene , brain

Diabetes February 2013, Vol.62, 706-708. doi:https://doi.org/10.2337/db12-1418

Evidenced-Based Antithrombotic Therapy for Acute Coronary Syndromes

Stefan James

Abstracts

View articletitled, Evidenced-Based Antithrombotic Therapy for Acute Coronary Syndromes

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Topics: acute coronary syndromes , aspirin , fibrinolytic agents , clopidogrel , plato trial

Diabetes February 2013, Vol.62, 709-710. doi:https://doi.org/10.2337/db12-1551

Metabolism

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

Wendy Keung; John R. Ussher; Jagdip S. Jaswal; Monique Raubenheimer; Victoria H.M. Lam; Cory S. Wagg; Gary D. Lopaschuk

Abstracts

View articletitled, Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

Supplementary data

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Topics: carnitine o-palmitoyltransferase , fatty acids , insulin resistance , mice , skeletal muscles

Diabetes February 2013, Vol.62, 711-720. doi:https://doi.org/10.2337/db12-0259

C-Reactive Protein Causes Insulin Resistance in Mice Through Fcγ Receptor IIB–Mediated Inhibition of Skeletal Muscle Glucose Delivery

Keiji Tanigaki; Wanpen Vongpatanasin; Jose A. Barrera; Dmitriy N. Atochin; Paul L. Huang; Ezio Bonvini; Philip W. Shaul; Chieko Mineo

Abstracts

View articletitled, C-Reactive Protein Causes Insulin Resistance in Mice Through Fcγ Receptor IIB–Mediated Inhibition of Skeletal Muscle Glucose Delivery

Supplementary data

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Topics: c-reactive protein , glucose , insulin , insulin resistance , mice

Diabetes February 2013, Vol.62, 721-731. doi:https://doi.org/10.2337/db12-0133

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Andrea Galmozzi; Nico Mitro; Alessandra Ferrari; Elise Gers; Federica Gilardi; Cristina Godio; Gaia Cermenati; Alice Gualerzi; Elena Donetti; Dante Rotili; Sergio Valente; Uliano Guerrini; Donatella Caruso; Antonello Mai; Enrique Saez; Emma De Fabiani; Maurizio Crestani

Abstracts

View articletitled, Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Supplementary data

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Topics: cell respiration , histone deacetylase , histone deacetylase inhibitors , mice , mitochondria

Diabetes February 2013, Vol.62, 732-742. doi:https://doi.org/10.2337/db12-0548

Adiponectin Corrects High-Fat Diet–Induced Disturbances in Muscle Metabolomic Profile and Whole-Body Glucose Homeostasis

Ying Liu; Subat Turdi; Taesik Park; Nicholas J. Morris; Yves Deshaies; Aimin Xu; Gary Sweeney

Abstracts

View articletitled, Adiponectin Corrects High-Fat Diet–Induced Disturbances in Muscle Metabolomic Profile and Whole-Body Glucose Homeostasis

Supplementary data

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Topics: adiponectin , metabolomics , mice , skeletal muscles

Diabetes February 2013, Vol.62, 743-752. doi:https://doi.org/10.2337/db12-0687

Hepatic Glucose Metabolism in Late Pregnancy: Normal Versus High-Fat and -Fructose Diet

Katie C. Coate; Marta S. Smith; Masakazu Shiota; Jose M. Irimia; Peter J. Roach; Ben Farmer; Phillip E. Williams; Mary Courtney Moore

Abstract

View articletitled, Hepatic Glucose Metabolism in Late Pregnancy: Normal Versus High-Fat and -Fructose Diet

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Topics: diet , dog, domestic , fructose , glucose , glucose metabolism

Diabetes February 2013, Vol.62, 753-761. doi:https://doi.org/10.2337/db12-0875

Telmisartan Improves Insulin Resistance of Skeletal Muscle Through Peroxisome Proliferator–Activated Receptor-δ Activation

Li Li; Zhidan Luo; Hao Yu; Xiaoli Feng; Peijian Wang; Jian Chen; Yunfei Pu; Yu Zhao; Hongbo He; Jian Zhong; Daoyan Liu; Zhiming Zhu

Abstracts

View articletitled, Telmisartan Improves Insulin Resistance of Skeletal Muscle Through Peroxisome Proliferator–Activated Receptor-δ Activation

Supplementary data

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Topics: insulin , insulin resistance , mice , skeletal muscles , skeletal myocytes

Diabetes February 2013, Vol.62, 762-774. doi:https://doi.org/10.2337/db12-0570

Adipocyte Fatty Acid Storage Factors Enhance Subcutaneous Fat Storage in Postmenopausal Women

Sylvia Santosa; Michael D. Jensen

Abstract

View articletitled, Adipocyte Fatty Acid Storage Factors Enhance Subcutaneous Fat Storage in Postmenopausal Women

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Topics: adipocytes , adipose tissue , postmenopause , premenopause , estrogen

Diabetes February 2013, Vol.62, 775-782. doi:https://doi.org/10.2337/db12-0912

Kinetics of Saturated, Monounsaturated, and Polyunsaturated Fatty Acids in Humans

Robert H. Nelson; Manpreet S. Mundi; Danielle T. Vlazny; Almira Smailovic; Kalpana Muthusamy; Jaime P. Almandoz; Ekta Singh; Michael D. Jensen; John M. Miles

Abstract

View articletitled, Kinetics of Saturated, Monounsaturated, and Polyunsaturated Fatty Acids in Humans

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Topics: drug clearance , fatty acids , palmitates , plasma , polyunsaturated fatty acids

Diabetes February 2013, Vol.62, 783-788. doi:https://doi.org/10.2337/db12-0367

Signal Transduction

The Wnt Signaling Pathway Effector TCF7L2 Controls Gut and Brain Proglucagon Gene Expression and Glucose Homeostasis

Weijuan Shao; Dingyan Wang; Yu-Ting Chiang; Wilfred Ip; Lingyun Zhu; Fenghao Xu; Joshua Columbus; Denise D. Belsham; David M. Irwin; Haibo Zhang; Xiaoyan Wen; Qinghua Wang; Tianru Jin

Abstracts

View articletitled, The Wnt Signaling Pathway Effector TCF7L2 Controls Gut and Brain Proglucagon Gene Expression and Glucose Homeostasis

Supplementary data

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Topics: brain , cyclic amp , forskolin , glucagon-like peptide 1 , glucose

Diabetes February 2013, Vol.62, 789-800. doi:https://doi.org/10.2337/db12-0365

Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

Damien Lanfray; Sébastien Arthaud; Johanne Ouellet; Vincent Compère; Jean-Luc Do Rego; Jérôme Leprince; Benjamin Lefranc; Hélène Castel; Cynthia Bouchard; Boris Monge-Roffarello; Denis Richard; Georges Pelletier; Hubert Vaudry; Marie-Christine Tonon; Fabrice Morin

Abstract

View articletitled, Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

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Topics: glucose , oligodeoxyribonucleotides , brain , hypothalamus

Diabetes February 2013, Vol.62, 801-810. doi:https://doi.org/10.2337/db11-0785

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

Abstracts

View articletitled, Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

Supplementary data

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Topics: insulin resistance , liver , mice , multicatalytic endopeptidase complex , obesity

Diabetes February 2013, Vol.62, 811-824. doi:https://doi.org/10.2337/db11-1652

Obesity Studies

Fenretinide Treatment Prevents Diet-Induced Obesity in Association With Major Alterations in Retinoid Homeostatic Gene Expression in Adipose, Liver, and Hypothalamus

George D. Mcilroy; Mirela Delibegovic; Carl Owen; Patrick N. Stoney; Kirsty D. Shearer; Peter J. McCaffery; Nimesh Mody

Abstract

View articletitled, Fenretinide Treatment Prevents Diet-Induced Obesity in Association With Major Alterations in Retinoid Homeostatic Gene Expression in Adipose, Liver, and Hypothalamus

Supplementary data

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Topics: diet , fenretinide , gene expression , heart failure , hypothalamus

Diabetes February 2013, Vol.62, 825-836. doi:https://doi.org/10.2337/db12-0458

Decreased Transcription of ChREBP-α/β Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes: Associations With Insulin Resistance and Hyperglycemia

Romy Kursawe; Sonia Caprio; Cosimo Giannini; Deepak Narayan; Aiping Lin; Ebe D’Adamo; Melissa Shaw; Bridget Pierpont; Samuel W. Cushman; Gerald I. Shulman

Abstract

View articletitled, Decreased Transcription of ChREBP-α/β Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes: Associations With Insulin Resistance and Hyperglycemia

Supplementary data

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Topics: adipose tissue , adolescent , biopsy , deuterium , diabetes mellitus, type 2

Diabetes February 2013, Vol.62, 837-844. doi:https://doi.org/10.2337/db12-0889

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

Peng Xue; Yongyong Hou; Yanyan Chen; Bei Yang; Jingqi Fu; Hongzhi Zheng; Kathy Yarborough; Courtney G. Woods; Dianxin Liu; Masayuki Yamamoto; Qiang Zhang; Melvin E. Andersen; Jingbo Pi

Abstracts

View articletitled, Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

Supplementary data

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Topics: insulin resistance , mice , ablation , antioxidants , insulin

Diabetes February 2013, Vol.62, 845-854. doi:https://doi.org/10.2337/db12-0584

Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients

Mohammed Qatanani; Yejun Tan; Radu Dobrin; Danielle M. Greenawalt; Guanghui Hu; Wenqing Zhao; Jerrold M. Olefsky; Dorothy D. Sears; Lee M. Kaplan; Daniel M. Kemp

Abstracts

View articletitled, Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients

Supplementary data

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Topics: adipose tissue , gene expression , genes , inflammation , insulin

Diabetes February 2013, Vol.62, 855-863. doi:https://doi.org/10.2337/db12-0399

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

Kevin Y. Lee; Steven J. Russell; Siegfried Ussar; Jeremie Boucher; Cecile Vernochet; Marcelo A. Mori; Graham Smyth; Michael Rourk; Carly Cederquist; Evan D. Rosen; Barbara B. Kahn; C. Ronald Kahn

Abstract

View articletitled, Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

Supplementary data

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Topics: fatty-acid-binding protein, adipocyte , mice , recombination, genetic , adipose tissue

Diabetes February 2013, Vol.62, 864-874. doi:https://doi.org/10.2337/db12-1089

Islet Studies

Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

Chad S. Hunter; Shilpy Dixit; Tsadok Cohen; Benjamin Ediger; Crystal Wilcox; Mark Ferreira; Heiner Westphal; Roland Stein; Catherine Lee May

Abstract

View articletitled, Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

Supplementary data

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Topics: endocrine cells , endocrine pancreas , hormones , insulin , mice

Diabetes February 2013, Vol.62, 875-886. doi:https://doi.org/10.2337/db12-0952

MicroRNA-7 Regulates the mTOR Pathway and Proliferation in Adult Pancreatic β-Cells

You Wang; Jiangying Liu; Chengyang Liu; Ali Naji; Doris A. Stoffers

Abstracts

View articletitled, MicroRNA-7 Regulates the mTOR Pathway and Proliferation in Adult Pancreatic β-Cells

Supplementary data

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Topics: mice , micrornas , mtor serine-threonine kinases , pancreas , signal transduction

Diabetes February 2013, Vol.62, 887-895. doi:https://doi.org/10.2337/db12-0451

Immunology and Transplantation

PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes–Associated Allele Is Not a Loss-of-Function Variant

Peilin Zheng; Stephan Kissler

Abstract

View articletitled, PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes–Associated Allele Is Not a Loss-of-Function Variant

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Topics: b-cell activation , diabetes mellitus, type 1 , doxycycline , heart sound p2 , mice

Diabetes February 2013, Vol.62, 896-904. doi:https://doi.org/10.2337/db12-0929

Local Autoantigen Expression as Essential Gatekeeper of Memory T-Cell Recruitment to Islet Grafts in Diabetic Hosts

Gonnie M. Alkemade; Xavier Clemente-Casares; Zhenguo Yu; Bao-You Xu; Jinguo Wang; Sue Tsai; James R. Wright, Jr.; Bart O. Roep; Pere Santamaria

Abstracts

View articletitled, Local Autoantigen Expression as Essential Gatekeeper of Memory T-Cell Recruitment to Islet Grafts in Diabetic Hosts

Supplementary data

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Topics: autoantigens , host (organism) , tissue transplants , t-lymphocytes , mice

Diabetes February 2013, Vol.62, 905-911. doi:https://doi.org/10.2337/db12-0600

Pathophysiology

Pathogenesis of A⁻β⁺ Ketosis-Prone Diabetes

Sanjeet G. Patel; Jean W. Hsu; Farook Jahoor; Ivonne Coraza; James R. Bain; Robert D. Stevens; Dinakar Iyer; Ramaswami Nalini; Kerem Ozer; Christiane S. Hampe; Christopher B. Newgard; Ashok Balasubramanyam

Abstracts

View articletitled, Pathogenesis of A−β+ Ketosis-Prone Diabetes

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Topics: amino acids , fatty acids , glutamate , glutamates , glutamine

Diabetes February 2013, Vol.62, 912-922. doi:https://doi.org/10.2337/db12-0624

Complications

The Neuropathic Diabetic Foot Ulcer Microbiome Is Associated With Clinical Factors

Sue E. Gardner; Stephen L. Hillis; Kris Heilmann; Julia A. Segre; Elizabeth A. Grice

Abstracts

View articletitled, The Neuropathic Diabetic Foot Ulcer Microbiome Is Associated With Clinical Factors

Supplementary data

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Topics: diabetic foot ulcer , microbiome , ulcer , rna, ribosomal, 16s , genes

Diabetes February 2013, Vol.62, 923-930. doi:https://doi.org/10.2337/db12-0771

RAGE Deficiency Improves Postinjury Sciatic Nerve Regeneration in Type 1 Diabetic Mice

Judyta K. Juranek; Matthew S. Geddis; Fei Song; Jinghua Zhang; Jose Garcia; Rosa Rosario; Shi Fang Yan; Thomas H. Brannagan; Ann Marie Schmidt

Abstract

View articletitled, RAGE Deficiency Improves Postinjury Sciatic Nerve Regeneration in Type 1 Diabetic Mice

Supplementary data

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Topics: macrophages , mice , rage , sciatic nerve , bone marrow

Diabetes February 2013, Vol.62, 931-943. doi:https://doi.org/10.2337/db12-0632

Endoplasmic Reticulum Stress Plays a Key Role in the Pathogenesis of Diabetic Peripheral Neuropathy

Sergey Lupachyk; Pierre Watcho; Roman Stavniichuk; Hanna Shevalye; Irina G. Obrosova

Abstracts

View articletitled, Endoplasmic Reticulum Stress Plays a Key Role in the Pathogenesis of Diabetic Peripheral Neuropathy

Supplementary data

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Topics: cyclophosphamide, doxorubicin, prednisone, and vincristine , diabetic neuropathies , mice , nerve fibers , rats

Diabetes February 2013, Vol.62, 944-952. doi:https://doi.org/10.2337/db12-0716

Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction

Domokos Gerö; Petra Szoleczky; Kunihiro Suzuki; Katalin Módis; Gabor Oláh; Ciro Coletta; Csaba Szabo

Abstracts

View articletitled, Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction

Supplementary data

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Topics: hyperglycemia , hyperglycemic agents , mitochondria , paroxetine , screening

Diabetes February 2013, Vol.62, 953-964. doi:https://doi.org/10.2337/db12-0789

Genetics / Genomes / Proteomics / Metabolomics

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study

Abstract

View articletitled, Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study

Supplementary data

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Topics: diabetes mellitus, type 2 , single nucleotide polymorphism , kvlqt1 , hmga2 protein , haplotypes

Diabetes February 2013, Vol.62, 965-976. doi:https://doi.org/10.2337/db12-0266

Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21

Abstracts

View articletitled, Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21

Supplementary data

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Topics: diabetes mellitus, type 2 , genotype determination , single nucleotide polymorphism , imputation , genome-wide association study

Diabetes February 2013, Vol.62, 977-986. doi:https://doi.org/10.2337/db12-0406

Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets

Mary E. Travers; Deborah J.G. Mackay; Marloes Dekker Nitert; Andrew P. Morris; Cecilia M. Lindgren; Andrew Berry; Paul R. Johnson; Neil Hanley; Leif C. Groop; Mark I. McCarthy; Anna L. Gloyn

Abstract

View articletitled, Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets

Supplementary data

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Topics: alleles , diabetes mellitus, type 2 , fetus , genotype , imprinting (psychology)

Diabetes February 2013, Vol.62, 987-992. doi:https://doi.org/10.2337/db12-0819

GATA6 Mutations Cause a Broad Phenotypic Spectrum of Diabetes From Pancreatic Agenesis to Adult-Onset Diabetes Without Exocrine Insufficiency

Elisa De Franco; Charles Shaw-Smith; Sarah E. Flanagan; Maggie H. Shepherd; International NDM Consortium; Andrew T. Hattersley; Sian Ellard

Abstracts

View articletitled, GATA6 Mutations Cause a Broad Phenotypic Spectrum of Diabetes From Pancreatic Agenesis to Adult-Onset Diabetes Without Exocrine Insufficiency

Supplementary data

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Topics: diabetes mellitus, type 2 , gata6 gene , mutation , pancreatic agenesis, congenital , phenotype

Diabetes February 2013, Vol.62, 993-997. doi:https://doi.org/10.2337/db12-0885

Errata

Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes 2011;60:614–624

M Al-Shabrawey; R Mussell; K Kahook; A Tawfik; M Eladl; V Sarthy; J Nussbaum; A El-Marakby; SY Park; Z Gurel; N Sheibani; KR Maddipati

Extract

View articletitled, Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes 2011;60:614–624

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Topics: arachidonate 12-lipoxygenase , ischemia , oxygen , proliferative diabetic retinopathy , retinal diseases

Diabetes February 2013, Vol.62, 998. doi:https://doi.org/10.2337/db13-er03

Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations. Diabetes 2012;61:2922–2931

AR Subauste; AK Das; X Li; B Elliot; C Evans; M El Azzouny; M Treutelaar; E Oral; T Leff; CF Burant

Extract

View articletitled, Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations. Diabetes 2012;61:2922–2931

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Topics: lipids , lipodystrophy , mutation , signal transduction

Diabetes February 2013, Vol.62, 998. doi:https://doi.org/10.2337/db13-er03a

Statement of Retraction

AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity. Diabetes 2012;61:3114–3125

W Zhang; X Zhang; H Wang; X Guo; H Li; Y Wang; X Xu; L Tan; MT Mashek; C Zhang; Y Chen; DG Mashek; M Foretz; C Zhu; H Zhou; X Liu; B Viollet; C Wu; Y Huo

Extract

View articletitled, AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity. Diabetes 2012;61:3114–3125

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Topics: diet , insulin resistance , obesity , protein kinase

Diabetes February 2013, Vol.62, 998. doi:https://doi.org/10.2337/db13-rt03

Issues and Events

Extract

View articletitled, Issues and Events

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Topics: atherosclerosis , chief complaint , cupressus , florida , wisconsin

Diabetes February 2013, Vol.62, 999. doi:https://doi.org/10.2337/db13-ie03

Diabetes Digests

Highlights From the Latest in Diabetes Research

Extract

View articletitled, Highlights From the Latest in Diabetes Research

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Topics: atypical , diabetic macular edema , diabetic retinopathy , laser therapy , metabolic syndrome x

Diabetes February 2013, Vol.62, 1000-1001. doi:https://doi.org/10.2337/db13-dd03

Issues

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In This Issue

Perspectives In Diabetes

Perspectives in Diabetes

Commentary

Metabolism

Signal Transduction

Obesity Studies

Islet Studies

Immunology and Transplantation

Pathophysiology

Complications

Genetics / Genomes / Proteomics / Metabolomics

Errata

Statement of Retraction

Issues and Events

Diabetes Digests

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