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Volume 63, Issue 7
July 2014
Diabetes Cover Image for Volume 63, Issue 7
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ISSN 0012-1797
EISSN 1939-327X
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In This Issue

In This Issue of Diabetes
View articletitled, In This Issue of <em>Diabetes</em>
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Diabetes June 2014, Vol.63, 2185-2186. doi:https://doi.org/10.2337/db14-ti07

Editor’s Note

A Special Thanks to the Reviewers of Diabetes
View articletitled, A Special Thanks to the Reviewers of <em>Diabetes</em>
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Diabetes June 2014, Vol.63, 2187. doi:https://doi.org/10.2337/db14-en07

Perspectives in Diabetes

Glycemic Goals in Diabetes: Trade-off Between Glycemic Control and Iatrogenic Hypoglycemia
Philip E. Cryer
View articletitled, Glycemic Goals in Diabetes: Trade-off Between Glycemic Control and Iatrogenic Hypoglycemia
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Diabetes June 2014, Vol.63, 2188-2195. doi:https://doi.org/10.2337/db14-0059
Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors
Bilal Omar; Bo Ahrén
View articletitled, Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors
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Diabetes June 2014, Vol.63, 2196-2202. doi:https://doi.org/10.2337/db14-0052

Commentaries

Is Type 1 Diabetes “Going Viral”?
Sarah J. Richardson; Marc S. Horwitz
View articletitled, Is Type 1 Diabetes “Going Viral”?
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Diabetes June 2014, Vol.63, 2203-2205. doi:https://doi.org/10.2337/db14-0510
Which Test for Diagnosing Early Human Diabetic Neuropathy?
Rayaz A. Malik
View articletitled, Which Test for Diagnosing Early Human Diabetic Neuropathy?
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Diabetes June 2014, Vol.63, 2206-2208. doi:https://doi.org/10.2337/db14-0492
Hyperglycemia and Adverse Outcomes in Acute Coronary Syndromes: Is Serum Glucose the Provocateur or Innocent Bystander?
Christina H. Wei; Sheldon E. Litwin
View articletitled, Hyperglycemia and Adverse Outcomes in Acute Coronary Syndromes: Is Serum Glucose the Provocateur or Innocent Bystander?
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Diabetes June 2014, Vol.63, 2209-2212. doi:https://doi.org/10.2337/db14-0571
Ghrelin and Insulin Secretion in Humans: Not a Tale of Two Hormones?
Rocco Barazzoni
View articletitled, Ghrelin and Insulin Secretion in Humans: Not a Tale of Two Hormones?
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Diabetes June 2014, Vol.63, 2213-2215. doi:https://doi.org/10.2337/db14-0407
Oxidative Stress and Obesity: The Chicken or the Egg?
Annayya R. Aroor; Vincent G. DeMarco
View articletitled, Oxidative Stress and Obesity: The Chicken or the Egg?
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Diabetes June 2014, Vol.63, 2216-2218. doi:https://doi.org/10.2337/db14-0424
Pancreatic Safety of Newer Incretin-Based Therapies: Are the “-tides” Finally Turning?
Sridevi Devaraj; Anirban Maitra
View articletitled, Pancreatic Safety of Newer Incretin-Based Therapies: Are the “-tides” Finally Turning?
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Diabetes June 2014, Vol.63, 2219-2221. doi:https://doi.org/10.2337/db14-0545
Overfeeding of Polyunsaturated Versus Saturated Fatty Acids Reduces Ectopic Fat
George A. Bray; Ronald M. Krauss
View articletitled, Overfeeding of Polyunsaturated Versus Saturated Fatty Acids Reduces Ectopic Fat
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Diabetes June 2014, Vol.63, 2222-2224. doi:https://doi.org/10.2337/db14-0493
Is the Gut the “Sweet Spot” for the Treatment of Diabetes?
Francesco Rubino; Stephanie A. Amiel
View articletitled, Is the Gut the “Sweet Spot” for the Treatment of Diabetes?
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Diabetes June 2014, Vol.63, 2225-2228. doi:https://doi.org/10.2337/db14-0402
Beyond Erythropoiesis: Emerging Metabolic Roles of Erythropoietin
Minna Woo; Meredith Hawkins
View articletitled, Beyond Erythropoiesis: Emerging Metabolic Roles of Erythropoietin
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Diabetes June 2014, Vol.63, 2229-2231. doi:https://doi.org/10.2337/db14-0566

Diabetes Symposium: Dementia and Diabetes

Insulin Action in Brain Regulates Systemic Metabolism and Brain Function
André Kleinridders; Heather A. Ferris; Weikang Cai; C. Ronald Kahn
View articletitled, Insulin Action in Brain Regulates Systemic Metabolism and Brain Function
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Diabetes June 2014, Vol.63, 2232-2243. doi:https://doi.org/10.2337/db14-0568
Brain Changes Underlying Cognitive Dysfunction in Diabetes: What Can We Learn From MRI?
Geert Jan Biessels; Yael D. Reijmer
View articletitled, Brain Changes Underlying Cognitive Dysfunction in Diabetes: What Can We Learn From MRI?
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Diabetes June 2014, Vol.63, 2244-2252. doi:https://doi.org/10.2337/db14-0348
Repurposing Diabetes Drugs for Brain Insulin Resistance in Alzheimer Disease
Mark Yarchoan; Steven E. Arnold
View articletitled, Repurposing Diabetes Drugs for Brain Insulin Resistance in Alzheimer Disease
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Diabetes June 2014, Vol.63, 2253-2261. doi:https://doi.org/10.2337/db14-0287
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
Fernanda G. De Felice; Sergio T. Ferreira
View articletitled, Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
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Diabetes June 2014, Vol.63, 2262-2272. doi:https://doi.org/10.2337/db13-1954

Metabolism

Elevated S-Adenosylhomocysteine Alters Adipocyte Functionality With Corresponding Changes in Gene Expression and Associated Epigenetic Marks
Sherry Ngo; Xiaoling Li; Renelle O’Neill; Chandrakanth Bhoothpur; Peter Gluckman; Allan Sheppard
View articletitled, Elevated S-Adenosylhomocysteine Alters Adipocyte Functionality With Corresponding Changes in Gene Expression and Associated Epigenetic Marks
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Diabetes June 2014, Vol.63, 2273-2283. doi:https://doi.org/10.2337/db13-1640
Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
Angela M. Hall; Nisreen Soufi; Kari T. Chambers; Zhouji Chen; George G. Schweitzer; Kyle S. McCommis; Derek M. Erion; Mark J. Graham; Xiong Su; Brian N. Finck
View articletitled, Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
Supplementary data
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Diabetes June 2014, Vol.63, 2284-2296. doi:https://doi.org/10.2337/db13-1502
Postexercise Improvement in Insulin-Stimulated Glucose Uptake Occurs Concomitant With Greater AS160 Phosphorylation in Muscle From Normal and Insulin-Resistant Rats
Carlos M. Castorena; Edward B. Arias; Naveen Sharma; Gregory D. Cartee
View articletitled, Postexercise Improvement in Insulin-Stimulated Glucose Uptake Occurs Concomitant With Greater AS160 Phosphorylation in Muscle From Normal and Insulin-Resistant Rats
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Diabetes June 2014, Vol.63, 2297-2308. doi:https://doi.org/10.2337/db13-1686
Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans
Jenny Tong; Harold W. Davis; Suzanne Summer; Stephen C. Benoit; Ahrar Haque; Martin Bidlingmaier; Matthias H. Tschöp; David D’Alessio
View articletitled, Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans
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Diabetes June 2014, Vol.63, 2309-2319. doi:https://doi.org/10.2337/db13-1598
Adipose-Specific Knockout of Seipin/Bscl2 Results in Progressive Lipodystrophy
Lu Liu; Qingqing Jiang; Xuhong Wang; Yuxi Zhang; Ruby C.Y. Lin; Sin Man Lam; Guanghou Shui; Linkang Zhou; Peng Li; Yuhui Wang; Xin Cui; Mingming Gao; Ling Zhang; Ying Lv; Guoheng Xu; George Liu; Dong Zhao; Hongyuan Yang
View articletitled, Adipose-Specific Knockout of <em>Seipin/Bscl2</em> Results in Progressive Lipodystrophy
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Diabetes June 2014, Vol.63, 2320-2331. doi:https://doi.org/10.2337/db13-0729

Obesity Studies

Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions
Daniela Nasteska; Norio Harada; Kazuyo Suzuki; Shunsuke Yamane; Akihiro Hamasaki; Erina Joo; Kanako Iwasaki; Kimitaka Shibue; Takanari Harada; Nobuya Inagaki
View articletitled, Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions
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Diabetes June 2014, Vol.63, 2332-2343. doi:https://doi.org/10.2337/db13-1563
Role of Vascular Oxidative Stress in Obesity and Metabolic Syndrome
Ji-Youn Youn; Kin Lung Siu; Heinrich E. Lob; Hana Itani; David G. Harrison; Hua Cai
View articletitled, Role of Vascular Oxidative Stress in Obesity and Metabolic Syndrome
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Diabetes June 2014, Vol.63, 2344-2355. doi:https://doi.org/10.2337/db13-0719
Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans
Fredrik Rosqvist; David Iggman; Joel Kullberg; Jonathan Cedernaes; Hans-Erik Johansson; Anders Larsson; Lars Johansson; Håkan Ahlström; Peter Arner; Ingrid Dahlman; Ulf Risérus
View articletitled, Overfeeding Polyunsaturated and Saturated Fat Causes Distinct Effects on Liver and Visceral Fat Accumulation in Humans
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Diabetes June 2014, Vol.63, 2356-2368. doi:https://doi.org/10.2337/db13-1622

Islet Studies

The p75 Neurotrophin Receptor Is Required for the Major Loss of Sympathetic Nerves From Islets Under Autoimmune Attack
Gerald J. Taborsky, Jr.; Qi Mei; Karin E. Bornfeldt; Daryl J. Hackney; Thomas O. Mundinger
View articletitled, The p75 Neurotrophin Receptor Is Required for the Major Loss of Sympathetic Nerves From Islets Under Autoimmune Attack
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Diabetes June 2014, Vol.63, 2369-2379. doi:https://doi.org/10.2337/db13-0778
RFamide Peptides 43RFa and 26RFa Both Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets but Exert Opposite Effects on Insulin Secretion
Riccarda Granata; Fabio Settanni; Letizia Trovato; Davide Gallo; Iacopo Gesmundo; Rita Nano; Maria Pia Gallo; Loredana Bergandi; Marco Volante; Giuseppe Alloatti; Lorenzo Piemonti; Jérôme Leprince; Mauro Papotti; Hubert Vaudry; Huy Ong; Ezio Ghigo
View articletitled, RFamide Peptides 43RFa and 26RFa Both Promote Survival of Pancreatic β-Cells and Human Pancreatic Islets but Exert Opposite Effects on Insulin Secretion
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Diabetes June 2014, Vol.63, 2380-2393. doi:https://doi.org/10.2337/db13-1522

Pathophysiology

Sitagliptin, a DPP-4 Inhibitor, Acutely Inhibits Intestinal Lipoprotein Particle Secretion in Healthy Humans
Changting Xiao; Satya Dash; Cecilia Morgantini; Bruce W. Patterson; Gary F. Lewis
View articletitled, Sitagliptin, a DPP-4 Inhibitor, Acutely Inhibits Intestinal Lipoprotein Particle Secretion in Healthy Humans
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Diabetes June 2014, Vol.63, 2394-2401. doi:https://doi.org/10.2337/db13-1654
Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility
Henna Kallionpää; Laura L. Elo; Essi Laajala; Juha Mykkänen; Isis Ricaño-Ponce; Matti Vaarma; Teemu D. Laajala; Heikki Hyöty; Jorma Ilonen; Riitta Veijola; Tuula Simell; Cisca Wijmenga; Mikael Knip; Harri Lähdesmäki; Olli Simell; Riitta Lahesmaa
View articletitled, Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility
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Diabetes June 2014, Vol.63, 2402-2414. doi:https://doi.org/10.2337/db13-1775
Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity
Mawadda Alnaeeli; Bruce M. Raaka; Oksana Gavrilova; Ruifeng Teng; Tatyana Chanturiya; Constance Tom Noguchi
View articletitled, Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity
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Diabetes June 2014, Vol.63, 2415-2431. doi:https://doi.org/10.2337/db13-0883

Complications

Diabetes Induces Lysine Acetylation of Intermediary Metabolism Enzymes in the Kidney
Hari Kosanam; Kerri Thai; Yanling Zhang; Andrew Advani; Kim A. Connelly; Eleftherios P. Diamandis; Richard E. Gilbert
View articletitled, Diabetes Induces Lysine Acetylation of Intermediary Metabolism Enzymes in the Kidney
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Diabetes June 2014, Vol.63, 2432-2439. doi:https://doi.org/10.2337/db12-1770
Role of Transcription Factor Acetylation in Diabetic Kidney Disease
Ruijie Liu; Yifei Zhong; Xuezhu Li; Haibing Chen; Belinda Jim; Ming-Ming Zhou; Peter Y. Chuang; John Cijiang He
View articletitled, Role of Transcription Factor Acetylation in Diabetic Kidney Disease
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Diabetes June 2014, Vol.63, 2440-2453. doi:https://doi.org/10.2337/db13-1810
Early Detection of Nerve Fiber Loss by Corneal Confocal Microscopy and Skin Biopsy in Recently Diagnosed Type 2 Diabetes
Dan Ziegler; Nikolaos Papanas; Andrey Zhivov; Stephan Allgeier; Karsten Winter; Iris Ziegler; Jutta Brüggemann; Alexander Strom; Sabine Peschel; Bernd Köhler; Oliver Stachs; Rudolf F. Guthoff; Michael Roden; for the German Diabetes Study (GDS) Group
View articletitled, Early Detection of Nerve Fiber Loss by Corneal Confocal Microscopy and Skin Biopsy in Recently Diagnosed Type 2 Diabetes
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Diabetes June 2014, Vol.63, 2454-2463. doi:https://doi.org/10.2337/db13-1819

Pharmacology and Therapeutics

Inhibition of SREBP Transcriptional Activity by a Boron-Containing Compound Improves Lipid Homeostasis in Diet-Induced Obesity
Xiaoping Zhao; Xiaoli; Haihong Zong; Arian Abdulla; Ellen S.T. Yang; Qun Wang; Jun-Yuan Ji; Jeffrey E. Pessin; Bhaskar C. Das; Fajun Yang
View articletitled, Inhibition of SREBP Transcriptional Activity by a Boron-Containing Compound Improves Lipid Homeostasis in Diet-Induced Obesity
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Diabetes June 2014, Vol.63, 2464-2473. doi:https://doi.org/10.2337/db13-0835
Impact of Acute Hyperglycemia on Myocardial Infarct Size, Area at Risk, and Salvage in Patients With STEMI and the Association With Exenatide Treatment: Results From a Randomized Study
Jacob Lønborg; Niels Vejlstrup; Henning Kelbæk; Lars Nepper-Christensen; Erik Jørgensen; Steffen Helqvist; Lene Holmvang; Kari Saunamäki; Hans Erik Bøtker; Won Yong Kim; Peter Clemmensen; Marek Treiman; Thomas Engstrøm
View articletitled, Impact of Acute Hyperglycemia on Myocardial Infarct Size, Area at Risk, and Salvage in Patients With STEMI and the Association With Exenatide Treatment: Results From a Randomized Study
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Diabetes June 2014, Vol.63, 2474-2485. doi:https://doi.org/10.2337/db13-1849
The Human GLP-1 Analogs Liraglutide and Semaglutide: Absence of Histopathological Effects on the Pancreas in Nonhuman Primates
Carsten F. Gotfredsen; Anne-Marie Mølck; Inger Thorup; Niels C. Berg Nyborg; Zaki Salanti; Lotte Bjerre Knudsen; Marianne O. Larsen
View articletitled, The Human GLP-1 Analogs Liraglutide and Semaglutide: Absence of Histopathological Effects on the Pancreas in Nonhuman Primates
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Diabetes June 2014, Vol.63, 2486-2497. doi:https://doi.org/10.2337/db13-1087
Glucose Sensing in the Peritoneal Space Offers Faster Kinetics Than Sensing in the Subcutaneous Space
Daniel R. Burnett; Lauren M. Huyett; Howard C. Zisser; Francis J. Doyle, III; Brett D. Mensh
View articletitled, Glucose Sensing in the Peritoneal Space Offers Faster Kinetics Than Sensing in the Subcutaneous Space
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Diabetes June 2014, Vol.63, 2498-2505. doi:https://doi.org/10.2337/db13-1649

Genetics / Genomes / Proteomics / Metabolomics

Risk of Type 1 Diabetes Progression in Islet Autoantibody-Positive Children Can Be Further Stratified Using Expression Patterns of Multiple Genes Implicated in Peripheral Blood Lymphocyte Activation and Function
Yulan Jin; Ashok Sharma; Shan Bai; Colleen Davis; Haitao Liu; Diane Hopkins; Kathy Barriga; Marian Rewers; Jin-Xiong She
View articletitled, Risk of Type 1 Diabetes Progression in Islet Autoantibody-Positive Children Can Be Further Stratified Using Expression Patterns of Multiple Genes Implicated in Peripheral Blood Lymphocyte Activation and Function
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Diabetes June 2014, Vol.63, 2506-2515. doi:https://doi.org/10.2337/db13-1716
BACH2, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic β-Cells via JNK1 Modulation and Crosstalk With the Candidate Gene PTPN2
Laura Marroquí; Izortze Santin; Reinaldo Sousa Dos Santos; Lorella Marselli; Piero Marchetti; Decio L. Eizirik
View articletitled, <em>BACH2</em>, a Candidate Risk Gene for Type 1 Diabetes, Regulates Apoptosis in Pancreatic β-Cells via JNK1 Modulation and Crosstalk With the Candidate Gene <em>PTPN2</em>
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Diabetes June 2014, Vol.63, 2516-2527. doi:https://doi.org/10.2337/db13-1443
PGC1α Promoter Methylation in Blood at 5–7 Years Predicts Adiposity From 9 to 14 Years (EarlyBird 50)
Rebecca Clarke-Harris; Terence J. Wilkin; Joanne Hosking; Jonathan Pinkney; Alison N. Jeffery; Brad S. Metcalf; Keith M. Godfrey; Linda D. Voss; Karen A. Lillycrop; Graham C. Burdge
View articletitled, PGC1α Promoter Methylation in Blood at 5–7 Years Predicts Adiposity From 9 to 14 Years (EarlyBird 50)
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Diabetes June 2014, Vol.63, 2528-2537. doi:https://doi.org/10.2337/db13-0671
A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes
Ricardo C. Ferreira; Hui Guo; Richard M.R. Coulson; Deborah J. Smyth; Marcin L. Pekalski; Oliver S. Burren; Antony J. Cutler; James D. Doecke; Shaun Flint; Eoin F. McKinney; Paul A. Lyons; Kenneth G.C. Smith; Peter Achenbach; Andreas Beyerlein; David B. Dunger; David G. Clayton; Linda S. Wicker; John A. Todd; Ezio Bonifacio; Chris Wallace; Anette-G. Ziegler
View articletitled, A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes
Supplementary data
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Diabetes June 2014, Vol.63, 2538-2550. doi:https://doi.org/10.2337/db13-1777
Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians
Peng Chen; Fumihiko Takeuchi; Jong-Young Lee; Huaixing Li; Jer-Yuarn Wu; Jun Liang; Jirong Long; Yasuharu Tabara; Mark O. Goodarzi; Mark A. Pereira; Young Jin Kim; Min Jin Go; Daniel O. Stram; Eranga Vithana; Chiea-Chuen Khor; Jianjun Liu; Jiemin Liao; Xingwang Ye; Yiqin Wang; Ling Lu; Terri L. Young; Jeannette Lee; Ah Chuan Thai; Ching-Yu Cheng; Rob M. van Dam; Yechiel Friedlander; Chew-Kiat Heng; Woon-Puay Koh; Chien-Hsiun Chen; Li-Ching Chang; Wen-Harn Pan; Qibin Qi; Masato Isono; Wei Zheng; Qiuyin Cai; Yutang Gao; Ken Yamamoto; Keizo Ohnaka; Ryoichi Takayanagi; Yoshikuni Kita; Hirotsugu Ueshima; Chao A. Hsiung; Jinrui Cui; Wayne H.-H. Sheu; Jerome I. Rotter; Yii-Der I. Chen; Chris Hsu; Yukinori Okada; Michiaki Kubo; Atsushi Takahashi; Toshihiro Tanaka; Frank J.A. van Rooij; Santhi K. Ganesh; Jinyan Huang; Tao Huang; Jianmin Yuan; Joo-Yeon Hwang; CHARGE Hematology Working Group; Myron D. Gross; Themistocles L. Assimes; Tetsuro Miki; Xiao-Ou Shu; Lu Qi; Yuan-Tson Chen; Xu Lin; Tin Aung; Tien-Yin Wong; Yik-Ying Teo; Bong-Jo Kim; Norihiro Kato; E-Shyong Tai
View articletitled, Multiple Nonglycemic Genomic Loci Are Newly Associated With Blood Level of Glycated Hemoglobin in East Asians
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Diabetes June 2014, Vol.63, 2551-2562. doi:https://doi.org/10.2337/db13-1815

Issues and Events

Issues and Events
View articletitled, Issues and Events
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Diabetes June 2014, Vol.63, 2563. doi:https://doi.org/10.2337/db14-ie07

E-Letters: Comments and Responses

Comment on Vassy et al. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172–2182
Ali Abbasi; Ronald P. Stolk; Stephan J.L. Bakker
View articletitled, Comment on Vassy et al. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172–2182
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Diabetes June 2014, Vol.63, e11-e12. doi:https://doi.org/10.2337/db14-0271
Response to Comment on Vassy et al. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172–2182
Jason L. Vassy; Marie-France Hivert; Marco Dauriz; James B. Meigs
View articletitled, Response to Comment on Vassy et al. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172–2182
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Diabetes June 2014, Vol.63, e13. doi:https://doi.org/10.2337/db14-0449
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities
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