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Volume 64, Issue 6
June 2015
Diabetes Cover Image for Volume 64, Issue 6
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ISSN 0012-1797
EISSN 1939-327X
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In This Issue

In This Issue of Diabetes
View articletitled, In This Issue of <em>Diabetes</em>
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Diabetes May 2015, Vol.64, 1869-1870. doi:https://doi.org/10.2337/db15-ti06

Editor’s Note

A Special Thanks to the Reviewers of Diabetes
View articletitled, A Special Thanks to the Reviewers of <em>Diabetes</em>
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Diabetes May 2015, Vol.64, 1871. doi:https://doi.org/10.2337/db15-en06

Perspectives in Diabetes

Human β-Cell Proliferation and Intracellular Signaling: Part 3
Andrew F. Stewart; Mehboob A. Hussain; Adolfo García-Ocaña; Rupangi C. Vasavada; Anil Bhushan; Ernesto Bernal-Mizrachi; Rohit N. Kulkarni
View articletitled, Human β-Cell Proliferation and Intracellular Signaling: Part 3
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Diabetes May 2015, Vol.64, 1872-1885. doi:https://doi.org/10.2337/db14-1843
Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?
Sue Tsai; Xavier Clemente-Casares; Xavier S. Revelo; Shawn Winer; Daniel A. Winer
View articletitled, Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?
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Diabetes May 2015, Vol.64, 1886-1897. doi:https://doi.org/10.2337/db14-1488

Commentaries

The Missing Link: Studying the Alternative TGF-β Pathway Provides a Unifying Theory for Different Components of Diabetic Nephropathy
Xiaoyi Zheng; Vivek Bhalla
View articletitled, The Missing Link: Studying the Alternative TGF-β Pathway Provides a Unifying Theory for Different Components of Diabetic Nephropathy
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Diabetes May 2015, Vol.64, 1898-1900. doi:https://doi.org/10.2337/db15-0184
AMPK-TBC1D4–Dependent Mechanism for Increasing Insulin Sensitivity of Skeletal Muscle
Gregory D. Cartee
View articletitled, AMPK-TBC1D4–Dependent Mechanism for Increasing Insulin Sensitivity of Skeletal Muscle
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Diabetes May 2015, Vol.64, 1901-1903. doi:https://doi.org/10.2337/db15-0010
Role of Perivascular Adipose Tissue on Vascular Reactive Oxygen Species in Type 2 Diabetes: A Give-and-Take Relationship
Jaume Padilla; Victoria J. Vieira-Potter; Guanghong Jia; James R. Sowers
View articletitled, Role of Perivascular Adipose Tissue on Vascular Reactive Oxygen Species in Type 2 Diabetes: A Give-and-Take Relationship
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Diabetes May 2015, Vol.64, 1904-1906. doi:https://doi.org/10.2337/db15-0096
Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms
Yuichi Hattori; Kohshi Hattori; Toshio Hayashi
View articletitled, Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms
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Diabetes May 2015, Vol.64, 1907-1909. doi:https://doi.org/10.2337/db15-0090
Bleach in the Diabetic Kidney Destabilizes Basement Membrane Collagen
Vincent M. Monnier
View articletitled, Bleach in the Diabetic Kidney Destabilizes Basement Membrane Collagen
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Diabetes May 2015, Vol.64, 1910-1911. doi:https://doi.org/10.2337/db15-0293
Therapeutic Window of Interleukin-2 for Autoimmune Diseases
Qizhi Tang
View articletitled, Therapeutic Window of Interleukin-2 for Autoimmune Diseases
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Diabetes May 2015, Vol.64, 1912-1913. doi:https://doi.org/10.2337/db15-0188

Metabolism

The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle
Jacqueline Stöckli; Christopher C. Meoli; Nolan J. Hoffman; Daniel J. Fazakerley; Himani Pant; Mark E. Cleasby; Xiuquan Ma; Maximilian Kleinert; Amanda E. Brandon; Jamie A. Lopez; Gregory J. Cooney; David E. James
View articletitled, The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle
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Diabetes January 2015, Vol.64, 1914-1922. doi:https://doi.org/10.2337/db13-1489
Liver-Specific Expression of Dominant-Negative Transcription Factor 7-Like 2 Causes Progressive Impairment in Glucose Homeostasis
Wilfred Ip; Weijuan Shao; Zhuolun Song; Zonglan Chen; Michael B. Wheeler; Tianru Jin
View articletitled, Liver-Specific Expression of Dominant-Negative Transcription Factor 7-Like 2 Causes Progressive Impairment in Glucose Homeostasis
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Diabetes January 2015, Vol.64, 1923-1932. doi:https://doi.org/10.2337/db14-1329
Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease
Auriel A. Willette; Nina Modanlo; Dimitrios Kapogiannis; for the Alzheimer’s Disease Neuroimaging Initiative
View articletitled, Insulin Resistance Predicts Medial Temporal Hypermetabolism in Mild Cognitive Impairment Conversion to Alzheimer Disease
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Diabetes January 2015, Vol.64, 1933-1940. doi:https://doi.org/10.2337/db14-1507
Foregut Exclusion Disrupts Intestinal Glucose Sensing and Alters Portal Nutrient and Hormonal Milieu
Atanu Pal; David B. Rhoads; Ali Tavakkoli
View articletitled, Foregut Exclusion Disrupts Intestinal Glucose Sensing and Alters Portal Nutrient and Hormonal Milieu
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Diabetes January 2015, Vol.64, 1941-1950. doi:https://doi.org/10.2337/db14-1578
A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism
Joshua R. Cook; Michihiro Matsumoto; Alexander S. Banks; Tadahiro Kitamura; Kyoichiro Tsuchiya; Domenico Accili
View articletitled, A Mutant Allele Encoding DNA Binding–Deficient FoxO1 Differentially Regulates Hepatic Glucose and Lipid Metabolism
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Diabetes January 2015, Vol.64, 1951-1965. doi:https://doi.org/10.2337/db14-1506
Effects of Intranasal Insulin on Hepatic Fat Accumulation and Energy Metabolism in Humans
Sofiya Gancheva; Chrysi Koliaki; Alessandra Bierwagen; Peter Nowotny; Martin Heni; Andreas Fritsche; Hans-Ulrich Häring; Julia Szendroedi; Michael Roden
View articletitled, Effects of Intranasal Insulin on Hepatic Fat Accumulation and Energy Metabolism in Humans
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Diabetes January 2015, Vol.64, 1966-1975. doi:https://doi.org/10.2337/db14-0892
Regulation of Glucose Tolerance and Sympathetic Activity by MC4R Signaling in the Lateral Hypothalamus
Donald A. Morgan; Latisha N. McDaniel; Terry Yin; Michael Khan; Jingwei Jiang; Michael R. Acevedo; Susan A. Walsh; Laura L. Boles Ponto; Andrew W. Norris; Michael Lutter; Kamal Rahmouni; Huxing Cui
View articletitled, Regulation of Glucose Tolerance and Sympathetic Activity by MC4R Signaling in the Lateral Hypothalamus
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Diabetes January 2015, Vol.64, 1976-1987. doi:https://doi.org/10.2337/db14-1257
Dipeptidyl Peptidase-4 Inhibition Ameliorates Western Diet–Induced Hepatic Steatosis and Insulin Resistance Through Hepatic Lipid Remodeling and Modulation of Hepatic Mitochondrial Function
Annayya R. Aroor; Javad Habibi; David A. Ford; Ravi Nistala; Guido Lastra; Camila Manrique; Merlow M. Dunham; Kaitlin D. Ford; John P. Thyfault; Elizabeth J. Parks; James R. Sowers; R. Scott Rector
View articletitled, Dipeptidyl Peptidase-4 Inhibition Ameliorates Western Diet–Induced Hepatic Steatosis and Insulin Resistance Through Hepatic Lipid Remodeling and Modulation of Hepatic Mitochondrial Function
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Diabetes January 2015, Vol.64, 1988-2001. doi:https://doi.org/10.2337/db14-0804
A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis
Kristin I. Stanford; Roeland J.W. Middelbeek; Kristy L. Townsend; Min-Young Lee; Hirokazu Takahashi; Kawai So; Kristen M. Hitchcox; Kathleen R. Markan; Katharina Hellbach; Michael F. Hirshman; Yu-Hua Tseng; Laurie J. Goodyear
View articletitled, A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis
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Diabetes January 2015, Vol.64, 2002-2014. doi:https://doi.org/10.2337/db14-0704
Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance
Jonas Benzler; Goutham K. Ganjam; Dominik Pretz; Rebecca Oelkrug; Christiane E. Koch; Karen Legler; Sigrid Stöhr; Carsten Culmsee; Lynda M. Williams; Alexander Tups
View articletitled, Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance
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Diabetes January 2015, Vol.64, 2015-2027. doi:https://doi.org/10.2337/db14-0093

Signal Transduction

Metformin Inhibits Monocyte-to-Macrophage Differentiation via AMPK-Mediated Inhibition of STAT3 Activation: Potential Role in Atherosclerosis
Sathish Babu Vasamsetti; Santosh Karnewar; Anantha Koteswararao Kanugula; Avinash Raj Thatipalli; Jerald Mahesh Kumar; Srigiridhar Kotamraju
View articletitled, Metformin Inhibits Monocyte-to-Macrophage Differentiation via AMPK-Mediated Inhibition of STAT3 Activation: Potential Role in Atherosclerosis
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Diabetes December 2014, Vol.64, 2028-2041. doi:https://doi.org/10.2337/db14-1225
Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner
Rasmus Kjøbsted; Jonas T. Treebak; Joachim Fentz; Louise Lantier; Benoit Viollet; Jesper B. Birk; Peter Schjerling; Marie Björnholm; Juleen R. Zierath; Jørgen F.P. Wojtaszewski
View articletitled, Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner
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Diabetes December 2014, Vol.64, 2042-2055. doi:https://doi.org/10.2337/db14-1402
miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140
Fang Hu; Min Wang; Ting Xiao; Bangqi Yin; Linyun He; Wen Meng; Meijuan Dong; Feng Liu
View articletitled, miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140
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Diabetes January 2015, Vol.64, 2056-2068. doi:https://doi.org/10.2337/db14-1117
Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity
Yan Chen; Rong Wu; Hang-zi Chen; Qian Xiao; Wei-jia Wang; Jian-ping He; Xiao-xue Li; Xian-wen Yu; Li Li; Peng Wang; Xi-chen Wan; Xin-hua Tian; Shu-jing Li; Xiang Yu; Qiao Wu
View articletitled, Enhancement of Hypothalamic STAT3 Acetylation by Nuclear Receptor Nur77 Dictates Leptin Sensitivity
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Diabetes January 2015, Vol.64, 2069-2081. doi:https://doi.org/10.2337/db14-1206

Obesity Studies

Blunted Brain Energy Consumption Relates to Insula Atrophy and Impaired Glucose Tolerance in Obesity
Kamila Jauch-Chara; Ferdinand Binkofski; Michaela Loebig; Kathrin Reetz; Gianna Jahn; Uwe H. Melchert; Ulrich Schweiger; Kerstin M. Oltmanns
View articletitled, Blunted Brain Energy Consumption Relates to Insula Atrophy and Impaired Glucose Tolerance in Obesity
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Diabetes January 2015, Vol.64, 2082-2091. doi:https://doi.org/10.2337/db14-0421
Overweight in Mice and Enhanced Adipogenesis In Vitro Are Associated With Lack of the Hedgehog Coreceptor Boc
Hye-Jin Lee; Shin-Bum Jo; Anthony I. Romer; Hyo-Jeong Lim; Min-Jung Kim; Seung-Hoi Koo; Robert S. Krauss; Jong-Sun Kang
View articletitled, Overweight in Mice and Enhanced Adipogenesis In Vitro Are Associated With Lack of the Hedgehog Coreceptor Boc
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Diabetes January 2015, Vol.64, 2092-2103. doi:https://doi.org/10.2337/db14-1017
Defects in Mitochondrial Efficiency and H2O2 Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training
Adam R. Konopka; Albert Asante; Ian R. Lanza; Matthew M. Robinson; Matthew L. Johnson; Chiara Dalla Man; Claudio Cobelli; Mark H. Amols; Brian A. Irving; K.S. Nair
View articletitled, Defects in Mitochondrial Efficiency and H<sub>2</sub>O<sub>2</sub> Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training
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Diabetes January 2015, Vol.64, 2104-2115. doi:https://doi.org/10.2337/db14-1701
Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity
Orla M. Finucane; Claire L. Lyons; Aoife M. Murphy; Clare M. Reynolds; Rut Klinger; Niamh P. Healy; Aoife A. Cooke; Rebecca C. Coll; Liam McAllan; Kanishka N. Nilaweera; Marcella E. O’Reilly; Audrey C. Tierney; Melissa J. Morine; Juan F. Alcala-Diaz; Jose Lopez-Miranda; Darran P. O’Connor; Luke A. O’Neill; Fiona C. McGillicuddy; Helen M. Roche
View articletitled, Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity
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Diabetes January 2015, Vol.64, 2116-2128. doi:https://doi.org/10.2337/db14-1098

Islet Studies

Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets
Martha L. Wall; Lynley D. Pound; Irina Trenary; Richard M. O’Brien; Jamey D. Young
View articletitled, Novel Stable Isotope Analyses Demonstrate Significant Rates of Glucose Cycling in Mouse Pancreatic Islets
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Diabetes December 2014, Vol.64, 2129-2137. doi:https://doi.org/10.2337/db14-0745
Manganese-Mediated MRI Signals Correlate With Functional β-Cell Mass During Diabetes Progression
Anke Meyer; Katharina Stolz; Wolfgang Dreher; Jennifer Bergemann; Vani Holebasavanahalli Thimmashetty; Navina Lueschen; Zahra Azizi; Vrushali Khobragade; Kathrin Maedler; Ekkehard Kuestermann
View articletitled, Manganese-Mediated MRI Signals Correlate With Functional β-Cell Mass During Diabetes Progression
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Diabetes March 2015, Vol.64, 2138-2147. doi:https://doi.org/10.2337/db14-0864
Distinct Roles of β-Cell Mass and Function During Type 1 Diabetes Onset and Remission
Helena Chmelova; Christian M. Cohrs; Julie A. Chouinard; Cathleen Petzold; Matthias Kuhn; Chunguang Chen; Ingo Roeder; Karsten Kretschmer; Stephan Speier
View articletitled, Distinct Roles of β-Cell Mass and Function During Type 1 Diabetes Onset and Remission
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Diabetes January 2015, Vol.64, 2148-2160. doi:https://doi.org/10.2337/db14-1055

Immunology and Transplantation

Reactivated CD4+Tm Cells of T1D Patients and Siblings Display an Exaggerated Effector Phenotype With Heightened Sensitivity to Activation-Induced Cell Death
Michael Lei Bian; Oscar Haigh; David Munster; Mark Harris; Andrew Cotterill; John J. Miles; Slavica Vuckovic
View articletitled, Reactivated CD4<sup>+</sup>Tm Cells of T1D Patients and Siblings Display an Exaggerated Effector Phenotype With Heightened Sensitivity to Activation-Induced Cell Death
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Diabetes December 2014, Vol.64, 2161-2171. doi:https://doi.org/10.2337/db14-1151
Selective IL-2 Responsiveness of Regulatory T Cells Through Multiple Intrinsic Mechanisms Supports the Use of Low-Dose IL-2 Therapy in Type 1 Diabetes
Aixin Yu; Isaac Snowhite; Francesco Vendrame; Michelle Rosenzwajg; David Klatzmann; Alberto Pugliese; Thomas R. Malek
View articletitled, Selective IL-2 Responsiveness of Regulatory T Cells Through Multiple Intrinsic Mechanisms Supports the Use of Low-Dose IL-2 Therapy in Type 1 Diabetes
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Diabetes January 2015, Vol.64, 2172-2183. doi:https://doi.org/10.2337/db14-1322
Reduced Expression of the MDA5 Gene IFIH1 Prevents Autoimmune Diabetes
Pamela J. Lincez; Iryna Shanina; Marc S. Horwitz
View articletitled, Reduced Expression of the MDA5 Gene <em>IFIH1</em> Prevents Autoimmune Diabetes
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Diabetes January 2015, Vol.64, 2184-2193. doi:https://doi.org/10.2337/db14-1223

Pathophysiology

Role of Plasminogen Activator Inhibitor-1 in Glucocorticoid-Induced Diabetes and Osteopenia in Mice
Yukinori Tamura; Naoyuki Kawao; Masato Yano; Kiyotaka Okada; Katsumi Okumoto; Yasutaka Chiba; Osamu Matsuo; Hiroshi Kaji
View articletitled, Role of Plasminogen Activator Inhibitor-1 in Glucocorticoid-Induced Diabetes and Osteopenia in Mice
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Diabetes December 2014, Vol.64, 2194-2206. doi:https://doi.org/10.2337/db14-1192

Complications

Adiponectin as a Link Between Type 2 Diabetes and Vascular NADPH Oxidase Activity in the Human Arterial Wall: The Regulatory Role of Perivascular Adipose Tissue
Alexios S. Antonopoulos; Marios Margaritis; Patricia Coutinho; Cheerag Shirodaria; Costas Psarros; Laura Herdman; Fabio Sanna; Ravi De Silva; Mario Petrou; Rana Sayeed; George Krasopoulos; Regent Lee; Janet Digby; Svetlana Reilly; Constantinos Bakogiannis; Dimitris Tousoulis; Benedikt Kessler; Barbara Casadei; Keith M. Channon; Charalambos Antoniades
View articletitled, Adiponectin as a Link Between Type 2 Diabetes and Vascular NADPH Oxidase Activity in the Human Arterial Wall: The Regulatory Role of Perivascular Adipose Tissue
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Diabetes December 2014, Vol.64, 2207-2219. doi:https://doi.org/10.2337/db14-1011
BAMBI Elimination Enhances Alternative TGF-β Signaling and Glomerular Dysfunction in Diabetic Mice
Ying Fan; Xuezhu Li; Wenzhen Xiao; Jia Fu; Ray C. Harris; Maja Lindenmeyer; Clemens D. Cohen; Nicolas Guillot; Margaret H. Baron; Niansong Wang; Kyung Lee; John C. He; Detlef Schlondorff; Peter Y. Chuang
View articletitled, BAMBI Elimination Enhances Alternative TGF-β Signaling and Glomerular Dysfunction in Diabetic Mice
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Diabetes January 2015, Vol.64, 2220-2233. doi:https://doi.org/10.2337/db14-1397
Diazoxide Improves Hormonal Counterregulatory Responses to Acute Hypoglycemia in Long-standing Type 1 Diabetes
Priya S. George; Roger Tavendale; Colin N.A. Palmer; Rory J. McCrimmon
View articletitled, Diazoxide Improves Hormonal Counterregulatory Responses to Acute Hypoglycemia in Long-standing Type 1 Diabetes
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Diabetes January 2015, Vol.64, 2234-2241. doi:https://doi.org/10.2337/db14-1539
Hypohalous Acids Contribute to Renal Extracellular Matrix Damage in Experimental Diabetes
Kyle L. Brown; Carl Darris; Kristie Lindsey Rose; Otto A. Sanchez; Hartman Madu; Josh Avance; Nickolas Brooks; Ming-Zhi Zhang; Agnes Fogo; Raymond Harris; Billy G. Hudson; Paul Voziyan
View articletitled, Hypohalous Acids Contribute to Renal Extracellular Matrix Damage in Experimental Diabetes
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Diabetes January 2015, Vol.64, 2242-2253. doi:https://doi.org/10.2337/db14-1001

Pharmacology and Therapeutics

Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model
Guillaume Vial; Marie-Agnès Chauvin; Nadia Bendridi; Annie Durand; Emmanuelle Meugnier; Anne-Marie Madec; Nathalie Bernoud-Hubac; Jean-Paul Pais de Barros; Éric Fontaine; Cécile Acquaviva; Sophie Hallakou-Bozec; Sébastien Bolze; Hubert Vidal; Jennifer Rieusset
View articletitled, Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model
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Diabetes December 2014, Vol.64, 2254-2264. doi:https://doi.org/10.2337/db14-1220

Genetics / Genomes / Proteomics / Metabolomics

Serum Proteomes Distinguish Children Developing Type 1 Diabetes in a Cohort With HLA-Conferred Susceptibility
Robert Moulder; Santosh D. Bhosale; Timo Erkkilä; Essi Laajala; Jussi Salmi; Elizabeth V. Nguyen; Henna Kallionpää; Juha Mykkänen; Mari Vähä-Mäkilä; Heikki Hyöty; Riitta Veijola; Jorma Ilonen; Tuula Simell; Jorma Toppari; Mikael Knip; David R. Goodlett; Harri Lähdesmäki; Olli Simell; Riitta Lahesmaa
View articletitled, Serum Proteomes Distinguish Children Developing Type 1 Diabetes in a Cohort With HLA-Conferred Susceptibility
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Diabetes January 2015, Vol.64, 2265-2278. doi:https://doi.org/10.2337/db14-0983
Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion
Hanieh Yaghootkar; Alena Stancáková; Rachel M. Freathy; Jagadish Vangipurapu; Michael N. Weedon; Weijia Xie; Andrew R. Wood; Ele Ferrannini; Andrea Mari; Susan M. Ring; Debbie A. Lawlor; George Davey Smith; Torben Jørgensen; Torben Hansen; Oluf Pedersen; Valgerdur Steinthorsdottir; Daniel F. Guðbjartsson; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Kari Stefansson; Andrew T. Hattersley; Mark Walker; Andrew D. Morris; Mark I. McCarthy; Colin N.A. Palmer; Markku Laakso; Timothy M. Frayling
View articletitled, Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at <em>CCND2</em> Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion
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Diabetes January 2015, Vol.64, 2279-2285. doi:https://doi.org/10.2337/db14-1456

Issues and Events

Issues and Events
View articletitled, Issues and Events
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Diabetes May 2015, Vol.64, 2286. doi:https://doi.org/10.2337/db15-ie06

E-Letters: Comments and Responses

Comment on Smith et al. Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation. Diabetes 2015;64:1555–1563
Francesco S. Dioguardi
View articletitled, Comment on Smith et al. Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation. Diabetes 2015;64:1555–1563
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Diabetes May 2015, Vol.64, e10. doi:https://doi.org/10.2337/db15-0149
Response to Comment on Smith et al. Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation. Diabetes 2015;64:1555–1563
Gordon I. Smith; Bettina Mittendorfer
View articletitled, Response to Comment on Smith et al. Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation. Diabetes 2015;64:1555–1563
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Diabetes May 2015, Vol.64, e11. doi:https://doi.org/10.2337/db15-0225
Comment on Chondronikola et al. Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans. Diabetes 2014;63:4089–4099
Flemming Dela; Jørn Wulff Helge
View articletitled, Comment on Chondronikola et al. Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans. Diabetes 2014;63:4089–4099
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Diabetes May 2015, Vol.64, e12-e13. doi:https://doi.org/10.2337/db15-0047
Response to Comment on Chondronikola et al. Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans. Diabetes 2014;63:4089–4099
Maria Chondronikola; Craig Porter; Martin E. Lidell; Labros S. Sidossis
View articletitled, Response to Comment on Chondronikola et al. Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans. Diabetes 2014;63:4089–4099
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Diabetes May 2015, Vol.64, e14-e15. doi:https://doi.org/10.2337/db15-0147
Comment on Gray et al. Insulin Regulates Brain Function, but How Does It Get There? Diabetes 2014;63:3992–3997
Konstantin Bloch; Daniel Lazard; Pnina Vardi
View articletitled, Comment on Gray et al. Insulin Regulates Brain Function, but How Does It Get There? Diabetes 2014;63:3992–3997
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Diabetes May 2015, Vol.64, e16. doi:https://doi.org/10.2337/db15-0217
Comment on Heni et al. Central Insulin Administration Improves Whole-Body Insulin Sensitivity via Hypothalamus and Parasympathetic Outputs in Men. Diabetes 2014;63:4083–4088
Sandeep Dhindsa; Gurkiran Dhindsa; Rama Chemitiganti
View articletitled, Comment on Heni et al. Central Insulin Administration Improves Whole-Body Insulin Sensitivity via Hypothalamus and Parasympathetic Outputs in Men. Diabetes 2014;63:4083–4088
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Diabetes May 2015, Vol.64, e7. doi:https://doi.org/10.2337/db15-0131
Response to Comment on Heni et al. Central Insulin Administration Improves Whole-Body Insulin Sensitivity via Hypothalamus and Parasympathetic Outputs in Men. Diabetes 2014;63:4083–4088
Martin Heni; Robert Wagner; Stephanie Kullmann; Hubert Preissl; Andreas Fritsche
View articletitled, Response to Comment on Heni et al. Central Insulin Administration Improves Whole-Body Insulin Sensitivity via Hypothalamus and Parasympathetic Outputs in Men. Diabetes 2014;63:4083–4088
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Diabetes May 2015, Vol.64, e8-e9. doi:https://doi.org/10.2337/db15-0209
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities
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