Skip Nav Destination
Issues
1 November 2016
-
Cover Image
Cover Image
On the cover: Inverted phase microscopy of purified human pancreatic islets stained by dithizone (diphenylthiocarbazone), obtained using the National Institutes of Health Clinical Islet Transplantation Consortium method. Credit: Camillo Ricordi, MD, Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL. His article “National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities,” appears in this issue of Diabetes (p. 3418).
Authors are invited to submit images for use on the cover of Diabetes. Black and white or color photographic or photomicrographic images are acceptable. Cover image submission and selection is completely independent of article submission and the peer-review process. Click here for more information. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes October 2016, Vol.65, 3223-3224. doi:https://doi.org/10.2337/db16-ti11
Perspectives in Diabetes
Regulation of Glucose Handling by the Skeleton: Insights From Mouse and Human Studies
Diabetes October 2016, Vol.65, 3225-3232. doi:https://doi.org/10.2337/db16-0053
Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease
Anette-G. Ziegler; Ezio Bonifacio; Alvin C. Powers; John A. Todd; Leonard C. Harrison; Mark A. Atkinson
Diabetes October 2016, Vol.65, 3233-3239. doi:https://doi.org/10.2337/db16-0687
Commentaries
Using Genotype-Based Recall to Estimate the Effects of AMY1 Copy Number Variation in Substrate Metabolism
Diabetes October 2016, Vol.65, 3240-3242. doi:https://doi.org/10.2337/dbi16-0046
Human Pancreatic Islet Production: From Research Protocols to Standardized Multicenter Manufacturing
Diabetes October 2016, Vol.65, 3243-3245. doi:https://doi.org/10.2337/dbi16-0045
The Insulin-Like Growth Factor Axis: A New Player in Gestational Diabetes Mellitus?
Diabetes October 2016, Vol.65, 3246-3248. doi:https://doi.org/10.2337/dbi16-0048
Metabolism
A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice
Kelsey H. Fisher-Wellman; Terence E. Ryan; Cody D. Smith; Laura A.A. Gilliam; Chien-Te Lin; Lauren R. Reese; Maria J. Torres; P. Darrell Neufer
Diabetes August 2016, Vol.65, 3249-3261. doi:https://doi.org/10.2337/db16-0291
FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice
Tong-Yan Liu; Xiao-Qing Xiong; Xing-Sheng Ren; Ming-Xia Zhao; Chang-Xiang Shi; Jue-Jin Wang; Ye-Bo Zhou; Feng Zhang; Ying Han; Xing-Ya Gao; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu
Diabetes August 2016, Vol.65, 3262-3275. doi:https://doi.org/10.2337/db16-0356
MicroRNA-451 Negatively Regulates Hepatic Glucose Production and Glucose Homeostasis by Targeting Glycerol Kinase–Mediated Gluconeogenesis
Shu Zhuo; Mengmei Yang; Yanan Zhao; Xiaofang Chen; Feifei Zhang; Na Li; Pengle Yao; Tengfei Zhu; Hong Mei; Shanshan Wang; Yu Li; Shiting Chen; Yingying Le
Diabetes August 2016, Vol.65, 3276-3288. doi:https://doi.org/10.2337/db16-0166
Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity
Laura K. Cole; Edgard M. Mejia; Marilyne Vandel; Genevieve C. Sparagna; Steven M. Claypool; Laura Dyck-Chan; Julianne Klein; Grant M. Hatch
Diabetes August 2016, Vol.65, 3289-3300. doi:https://doi.org/10.2337/db16-0114
White Adipocyte Adiponectin Exocytosis Is Stimulated via β3-Adrenergic Signaling and Activation of Epac1: Catecholamine Resistance in Obesity and Type 2 Diabetes
Ali M. Komai; Saliha Musovic; Eduard Peris; Ahmed Alrifaiy; Mickaël F. El Hachmane; Marcus Johansson; Ingrid Wernstedt Asterholm; Charlotta S. Olofsson
Diabetes August 2016, Vol.65, 3301-3313. doi:https://doi.org/10.2337/db15-1597
Association Between Long-term Exposure to Air Pollution and Biomarkers Related to Insulin Resistance, Subclinical Inflammation, and Adipokines
Kathrin Wolf; Anita Popp; Alexandra Schneider; Susanne Breitner; Regina Hampel; Wolfgang Rathmann; Christian Herder; Michael Roden; Wolfgang Koenig; Christa Meisinger; Annette Peters; for the KORA-Study Group
Diabetes September 2016, Vol.65, 3314-3326. doi:https://doi.org/10.2337/db15-1567
The Inactivation of RabGAP Function of AS160 Promotes Lysosomal Degradation of GLUT4 and Causes Postprandial Hyperglycemia and Hyperinsulinemia
Diabetes August 2016, Vol.65, 3327-3340. doi:https://doi.org/10.2337/db16-0416
Deficiency in the Heat Stress Response Could Underlie Susceptibility to Metabolic Disease
Robert S. Rogers; E. Matthew Morris; Joshua L. Wheatley; Ashley E. Archer; Colin S. McCoin; Kathleen S. White; David R. Wilson; Grace M.E. Meers; Lauren G. Koch; Steven L. Britton; John P. Thyfault; Paige C. Geiger
Diabetes August 2016, Vol.65, 3341-3351. doi:https://doi.org/10.2337/db16-0292
Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1
Brennan K. Smith; Rebecca J. Ford; Eric M. Desjardins; Alex E. Green; Meghan C. Hughes; Vanessa P. Houde; Emily A. Day; Katarina Marcinko; Justin D. Crane; Emilio P. Mottillo; Christopher G.R. Perry; Bruce E. Kemp; Mark A. Tarnopolsky; Gregory R. Steinberg
Diabetes August 2016, Vol.65, 3352-3361. doi:https://doi.org/10.2337/db16-0564
Metabolomic Profile of Low–Copy Number Carriers at the Salivary α-Amylase Gene Suggests a Metabolic Shift Toward Lipid-Based Energy Production
Abdelilah Arredouani; Matteo Stocchero; Nicola Culeddu; Julia El-Sayed Moustafa; D.E.S.I.R. Study Group; Jean Tichet; Beverley Balkau; Thierry Brousseau; Marco Manca; Mario Falchi
Diabetes July 2016, Vol.65, 3362-3368. doi:https://doi.org/10.2337/db16-0315
Signal Transduction
CREBH Couples Circadian Clock With Hepatic Lipid Metabolism
Ze Zheng; Hyunbae Kim; Yining Qiu; Xuequn Chen; Roberto Mendez; Aditya Dandekar; Xuebao Zhang; Chunbin Zhang; Andrew C. Liu; Lei Yin; Jiandie D. Lin; Paul D. Walker; Gregory Kapatos; Kezhong Zhang
Diabetes August 2016, Vol.65, 3369-3383. doi:https://doi.org/10.2337/db16-0298
Obesity Studies
Loss of Mbd2 Protects Mice Against High-Fat Diet–Induced Obesity and Insulin Resistance by Regulating the Homeostasis of Energy Storage and Expenditure
Jia Cheng; Jia Song; Xiaoyu He; Meng Zhang; Shuang Hu; Shu Zhang; Qilin Yu; Ping Yang; Fei Xiong; Dao Wen Wang; Jianfeng Zhou; Qin Ning; Zhishui Chen; Decio L. Eizirik; Zhiguang Zhou; Chunxia Zhao; Cong-Yi Wang
Diabetes August 2016, Vol.65, 3384-3395. doi:https://doi.org/10.2337/db16-0151
Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance
Hao Yang; Jiang W. Wu; Shu P. Wang; Ilenia Severi; Loris Sartini; Norma Frizzell; Saverio Cinti; Gongshe Yang; Grant A. Mitchell
Diabetes August 2016, Vol.65, 3396-3409. doi:https://doi.org/10.2337/db16-0136
FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency
Lucile Dollet; Clara Levrel; Tamer Coskun; Soazig Le Lay; Cedric Le May; Audrey Ayer; Quentin Venara; Andrew C. Adams; Ruth E. Gimeno; Jocelyne Magré; Bertrand Cariou; Xavier Prieur
Diabetes August 2016, Vol.65, 3410-3417. doi:https://doi.org/10.2337/db16-0327
Islet Studies
National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities
Camillo Ricordi; Julia S. Goldstein; A.N. Balamurugan; Gregory L. Szot; Tatsuya Kin; Chengyang Liu; Christine W. Czarniecki; Barbara Barbaro; Nancy D. Bridges; Jose Cano; William R. Clarke; Thomas L. Eggerman; Lawrence G. Hunsicker; Dixon B. Kaufman; Aisha Khan; David-Erick Lafontant; Elina Linetsky; Xunrong Luo; James F. Markmann; Ali Naji; Olle Korsgren; Jose Oberholzer; Nicole A. Turgeon; Daniel Brandhorst; Xiaojuan Chen; Andrew S. Friberg; Ji Lei; Ling-jia Wang; Joshua J. Wilhelm; Jamie Willits; Xiaomin Zhang; Bernhard J. Hering; Andrew M. Posselt; Peter G. Stock; A.M. James Shapiro
Diabetes July 2016, Vol.65, 3418-3428. doi:https://doi.org/10.2337/db16-0234
Immunology and Transplantation
Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes
Terri C. Thayer; James A. Pearson; Evy De Leenheer; Stephanie J. Hanna; Joanne Boldison; Joanne Davies; Adrian Tsui; Sartaj Ahmed; Peter Easton; Lai Khai Siew; Li Wen; F. Susan Wong
Diabetes August 2016, Vol.65, 3429-3439. doi:https://doi.org/10.2337/db15-1649
Adipose Recruitment and Activation of Plasmacytoid Dendritic Cells Fuel Metaflammation
Amrit Raj Ghosh; Roopkatha Bhattacharya; Shamik Bhattacharya; Titli Nargis; Oindrila Rahaman; Pritam Duttagupta; Deblina Raychaudhuri; Chinky Shiu Chen Liu; Shounak Roy; Parasar Ghosh; Shashi Khanna; Tamonas Chaudhuri; Om Tantia; Stefan Haak; Santu Bandyopadhyay; Satinath Mukhopadhyay; Partha Chakrabarti; Dipyaman Ganguly
Diabetes August 2016, Vol.65, 3440-3452. doi:https://doi.org/10.2337/db16-0331
Pathophysiology
Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet
Malini S. Iyer; Richard N. Bergman; Jeremy E. Korman; Orison O. Woolcott; Morvarid Kabir; Ronald G. Victor; Deborah J. Clegg; Cathryn Kolka
Diabetes August 2016, Vol.65, 3453-3463. doi:https://doi.org/10.2337/db16-0698
Metabolic Aberrations Impact Biophysical Integrity of Macromolecular Protein Pools in the Default Mode Network
Diabetes August 2016, Vol.65, 3464-3472. doi:https://doi.org/10.2337/db15-1714
Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation
Kristine Færch; Dorte Vistisen; Giovanni Pacini; Signe S. Torekov; Nanna B. Johansen; Daniel R. Witte; Anna Jonsson; Oluf Pedersen; Torben Hansen; Torsten Lauritzen; Marit E. Jørgensen; Bo Ahrén; Jens Juul Holst
Diabetes August 2016, Vol.65, 3473-3481. doi:https://doi.org/10.2337/db16-0240
F1F0 ATP Synthase–Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline
Shijun Yan; Fang Du; Long Wu; Zhihua Zhang; Changjia Zhong; Qing Yu; Yongfu Wang; Lih-Fen Lue; Douglas G. Walker; Justin T. Douglas; Shirley ShiDu Yan
Diabetes August 2016, Vol.65, 3482-3494. doi:https://doi.org/10.2337/db16-0556
Complications
Enhanced Integrin α4β1–Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes
Wesley T. Abplanalp; Daniel J. Conklin; Joseph M. Cantor; Mark H. Ginsberg; Marcin Wysoczynski; Aruni Bhatnagar; Timothy E. O’Toole
Diabetes August 2016, Vol.65, 3505-3515. doi:https://doi.org/10.2337/db16-0634
Errata
Erratum. In This Issue of Diabetes. Diabetes 2016;65:2465–2466
Diabetes October 2016, Vol.65, 3516. doi:https://doi.org/10.2337/db16-er11a
Erratum. Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties. Diabetes 2016;65:2580–2590
Ondrej Kuda; Marie Brezinova; Martina Rombaldova; Barbora Slavikova; Martin Posta; Petr Beier; Petra Janovska; Jiri Veleba; Jan Kopecky, Jr.; Eva Kudova; Terezie Pelikanova; Jan Kopecky
Diabetes October 2016, Vol.65, 3516. doi:https://doi.org/10.2337/db16-er11b
