Skip Nav Destination
Issues
1 July 2016
-
Cover Image
Cover Image
- PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 0012-1797
EISSN 1939-327X
In this Issue
In This Issue
In This Issue of Diabetes
Diabetes June 2016, Vol.65, 1755-1756. doi:https://doi.org/10.2337/db16-ti07
Perspectives in Diabetes
Pharmacological Targeting of the Atherogenic Dyslipidemia Complex: The Next Frontier in CVD Prevention Beyond Lowering LDL Cholesterol
Diabetes June 2016, Vol.65, 1767-1778. doi:https://doi.org/10.2337/db16-0046
Illuminating the Effects of Stroke on the Diabetic Brain: Insights From Imaging Neural and Vascular Networks in Experimental Animal Models
Diabetes June 2016, Vol.65, 1779-1788. doi:https://doi.org/10.2337/db16-0064
Commentaries
How Kiss-and-Run Can Make Us Sick: SOX4 Puts a Break on the Pore
Diabetes June 2016, Vol.65, 1791-1793. doi:https://doi.org/10.2337/dbi16-0019
Diabetes Symposium: Bioactive Lipids and Nonpeptide Mediators of Metabolism
De Novo Lipogenesis Products and Endogenous Lipokines
Diabetes June 2016, Vol.65, 1800-1807. doi:https://doi.org/10.2337/db16-0251
Metabolism
Early Low-Fat Diet Enriched With Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High-Fat Diet Challenge in Mice
Laurent Demizieux; Fabiana Piscitelli; Stephanie Troy-Fioramonti; Fabio Arturo Iannotti; Simona Borrino; Joseph Gresti; Tania Muller; Jerome Bellenger; Cristoforo Silvestri; Vincenzo Di Marzo; Pascal Degrace
Diabetes April 2016, Vol.65, 1824-1837. doi:https://doi.org/10.2337/db15-1279
Dual Actions of Apolipoprotein A-I on Glucose-Stimulated Insulin Secretion and Insulin-Independent Peripheral Tissue Glucose Uptake Lead to Increased Heart and Skeletal Muscle Glucose Disposal
Joan Domingo-Espín; Maria Lindahl; Oktawia Nilsson-Wolanin; Samuel W. Cushman; Karin G. Stenkula; Jens O. Lagerstedt
Diabetes April 2016, Vol.65, 1838-1848. doi:https://doi.org/10.2337/db15-1493
Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes
Sofiya Gancheva; Alessandra Bierwagen; Kirti Kaul; Christian Herder; Peter Nowotny; Sabine Kahl; Guido Giani; Birgit Klueppelholz; Birgit Knebel; Paul Begovatz; Klaus Strassburger; Hadi Al-Hasani; Jesper Lundbom; Julia Szendroedi; Michael Roden; for the German Diabetes Study (GDS) Group
Diabetes April 2016, Vol.65, 1849-1857. doi:https://doi.org/10.2337/db16-0162
Fasting Plasma Insulin Concentrations Are Associated With Changes in Hepatic Fatty Acid Synthesis and Partitioning Prior to Changes in Liver Fat Content in Healthy Adults
Camilla Pramfalk; Michael Pavlides; Rajarshi Banerjee; Catriona A. McNeil; Stefan Neubauer; Fredrik Karpe; Leanne Hodson
Diabetes April 2016, Vol.65, 1858-1867. doi:https://doi.org/10.2337/db16-0236
Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity
Hyeon-Ju Jeong; Hye-Jin Lee; Tuan Anh Vuong; Kyu-Sil Choi; Dahee Choi; Sung-Hoi Koo; Sung Chun Cho; Hana Cho; Jong-Sun Kang
Diabetes April 2016, Vol.65, 1868-1882. doi:https://doi.org/10.2337/db15-1500
Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice
John R. Ussher; Natasha Fillmore; Wendy Keung; Liyan Zhang; Jun Mori; Vaninder K. Sidhu; Arata Fukushima; Keshav Gopal; David G. Lopaschuk; Cory S. Wagg; Jagdip S. Jaswal; Jason R.B. Dyck; Gary D. Lopaschuk
Diabetes May 2016, Vol.65, 1883-1891. doi:https://doi.org/10.2337/db15-1145
Signal Transduction
Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1–40/42 and Phospho-Tau May Abet Alzheimer Development
Mini Sajan; Barbara Hansen; Robert Ivey, III; Joshua Sajan; Csilla Ari; Shijie Song; Ursula Braun; Michael Leitges; Margaret Farese-Higgs; Robert V. Farese
Diabetes February 2016, Vol.65, 1892-1903. doi:https://doi.org/10.2337/db15-1428
Hepatic ATF6 Increases Fatty Acid Oxidation to Attenuate Hepatic Steatosis in Mice Through Peroxisome Proliferator–Activated Receptor α
Xuqing Chen; Feifei Zhang; Qi Gong; Aoyuan Cui; Shu Zhuo; Zhimin Hu; Yamei Han; Jing Gao; Yixuan Sun; Zhengshuai Liu; Zhongnan Yang; Yingying Le; Xianfu Gao; Lily Q. Dong; Xin Gao; Yu Li
Diabetes April 2016, Vol.65, 1904-1915. doi:https://doi.org/10.2337/db15-1637
Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes
Meghan Sauvé; Sonya K. Hui; Danny D. Dinh; Warren D. Foltz; Abdul Momen; Sergei A. Nedospasov; Stefan Offermanns; Mansoor Husain; Jeffrey T. Kroetsch; Darcy Lidington; Steffen-Sebastian Bolz
Diabetes April 2016, Vol.65, 1916-1928. doi:https://doi.org/10.2337/db15-1450
Obesity Studies
Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents
Ania M. Jastreboff; Rajita Sinha; Jagriti Arora; Cosimo Giannini; Jessica Kubat; Saima Malik; Michelle A. Van Name; Nicola Santoro; Mary Savoye; Elvira J. Duran; Bridget Pierpont; Gary Cline; R. Todd Constable; Robert S. Sherwin; Sonia Caprio
Diabetes April 2016, Vol.65, 1929-1939. doi:https://doi.org/10.2337/db15-1216
Islet Studies
Amelioration of Diabetes by Protein S
Taro Yasuma; Yutaka Yano; Corina N. D’Alessandro-Gabazza; Masaaki Toda; Paloma Gil-Bernabe; Tetsu Kobayashi; Kota Nishihama; Josephine A. Hinneh; Rumi Mifuji-Moroka; Ziaurahman Roeen; John Morser; Isaac Cann; Iwasa Motoh; Yoshiyuki Takei; Esteban C. Gabazza
Diabetes May 2016, Vol.65, 1940-1951. doi:https://doi.org/10.2337/db15-1404
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion
Stephan C. Collins; Hyun Woong Do; Benoit Hastoy; Alison Hugill; Julie Adam; Margarita V. Chibalina; Juris Galvanovskis; Mahdieh Godazgar; Sheena Lee; Michelle Goldsworthy; Albert Salehi; Andrei I. Tarasov; Anders H. Rosengren; Roger Cox; Patrik Rorsman
Diabetes March 2016, Vol.65, 1952-1961. doi:https://doi.org/10.2337/db15-1489
Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells
Subhankar Dolai; Li Xie; Dan Zhu; Tao Liang; Tairan Qin; Huanli Xie; Youhou Kang; Edwin R. Chapman; Herbert Y. Gaisano
Diabetes April 2016, Vol.65, 1962-1976. doi:https://doi.org/10.2337/db15-1436
Immunology and Transplantation
B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice
Caroline M. Leeth; Jeremy Racine; Harold D. Chapman; Berta Arpa; Jorge Carrillo; Jorge Carrascal; Qiming Wang; Jeremy Ratiu; Leire Egia-Mendikute; Estela Rosell-Mases; Thomas Stratmann; Joan Verdaguer; David V. Serreze
Diabetes March 2016, Vol.65, 1977-1987. doi:https://doi.org/10.2337/db15-1606
Pathophysiology
Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study
Helena Elding Larsson; Kendra Vehik; Michael J. Haller; Xiang Liu; Beena Akolkar; William Hagopian; Jeffrey Krischer; Åke Lernmark; Jin-Xiong She; Olli Simell; Jorma Toppari; Anette-G. Ziegler; Marian Rewers; for the TEDDY Study Group
Diabetes March 2016, Vol.65, 1988-1995. doi:https://doi.org/10.2337/db15-1180
Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice
Keiji Tanigaki; Ken L. Chambliss; Ivan S. Yuhanna; Anastasia Sacharidou; Mohamed Ahmed; Dmitriy N. Atochin; Paul L. Huang; Philip W. Shaul; Chieko Mineo
Diabetes April 2016, Vol.65, 1996-2005. doi:https://doi.org/10.2337/db15-1605
Complications
Mast Cells Regulate Wound Healing in Diabetes
Ana Tellechea; Ermelindo C. Leal; Antonios Kafanas; Michael E. Auster; Sarada Kuchibhotla; Yana Ostrovsky; Francesco Tecilazich; Dimitrios Baltzis; Yongjun Zheng; Eugénia Carvalho; Janice M. Zabolotny; Zuyi Weng; Anastasia Petra; Arti Patel; Smaro Panagiotidou; Leena Pradhan-Nabzdyk; Theoharis C. Theoharides; Aristidis Veves
Diabetes April 2016, Vol.65, 2006-2019. doi:https://doi.org/10.2337/db15-0340
microRNA-182 Mediates Sirt1-Induced Diabetic Corneal Nerve Regeneration
Diabetes April 2016, Vol.65, 2020-2031. doi:https://doi.org/10.2337/db15-1283
Pharmacology and Therapeutics
Empagliflozin, via Switching Metabolism Toward Lipid Utilization, Moderately Increases LDL Cholesterol Levels Through Reduced LDL Catabolism
François Briand; Eric Mayoux; Emmanuel Brousseau; Noémie Burr; Isabelle Urbain; Clément Costard; Michael Mark; Thierry Sulpice
Diabetes April 2016, Vol.65, 2032-2038. doi:https://doi.org/10.2337/db16-0049
Genetics / Genomes / Proteomics / Metabolomics
Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth
Denise M. Scholtens; James R. Bain; Anna C. Reisetter; Michael J. Muehlbauer; Michael Nodzenski; Robert D. Stevens; Olga Ilkayeva; Lynn P. Lowe; Boyd E. Metzger; Christopher B. Newgard; William L. Lowe, Jr.; for the HAPO Study Cooperative Research Group
Diabetes April 2016, Vol.65, 2039-2050. doi:https://doi.org/10.2337/db15-1748
Discovery of a Genetic Metabolic Cause for Mauriac Syndrome in Type 1 Diabetes
Michael J. MacDonald; Noaman M. Hasan; Israr-ul H. Ansari; Melissa J. Longacre; Mindy A. Kendrick; Scott W. Stoker
Diabetes April 2016, Vol.65, 2051-2059. doi:https://doi.org/10.2337/db16-0099
New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins
Delnaz Roshandel; Ronald Klein; Barbara E.K. Klein; Bruce H.R. Wolffenbuttel; Melanie M. van der Klauw; Jana V. van Vliet-Ostaptchouk; Gil Atzmon; Danny Ben-Avraham; Jill P. Crandall; Nir Barzilai; Shelley B. Bull; Angelo J. Canty; S. Mohsen Hosseini; Linda T. Hiraki; John Maynard; David R. Sell; Vincent M. Monnier; Patricia A. Cleary; Barbara H. Braffett; the DCCT/EDIC Research Group; Andrew D. Paterson
Diabetes April 2016, Vol.65, 2060-2071. doi:https://doi.org/10.2337/db15-1484
Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium
Nicholette D. Palmer; Lynne E. Wagenknecht; Carl D. Langefeld; Nan Wang; Thomas A. Buchanan; Anny H. Xiang; Hooman Allayee; Richard N. Bergman; Leslie J. Raffel; Yii-Der Ida Chen; Talin Haritunians; Tasha Fingerlin; Mark O. Goodarzi; Kent D. Taylor; Jerome I. Rotter; Richard M. Watanabe; Donald W. Bowden
Diabetes May 2016, Vol.65, 2072-2080. doi:https://doi.org/10.2337/db15-1543
The Genetic Program of Pancreatic β-Cell Replication In Vivo
Agnes Klochendler; Inbal Caspi; Noa Corem; Maya Moran; Oriel Friedlich; Sharona Elgavish; Yuval Nevo; Aharon Helman; Benjamin Glaser; Amir Eden; Shalev Itzkovitz; Yuval Dor
Diabetes March 2016, Vol.65, 2081-2093. doi:https://doi.org/10.2337/db16-0003
Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes
Kashyap A. Patel; Richard A. Oram; Sarah E. Flanagan; Elisa De Franco; Kevin Colclough; Maggie Shepherd; Sian Ellard; Michael N. Weedon; Andrew T. Hattersley
Diabetes April 2016, Vol.65, 2094-2099. doi:https://doi.org/10.2337/db15-1690
Erratum
Erratum. The Effects of Type 2 Diabetes on Lipoprotein Composition and Arterial Stiffness in Male Youth. Diabetes 2013;62:2958–2967
Scott M. Gordon; W. Sean Davidson; Elaine M. Urbina; Lawrence M. Dolan; Anna Heink; Huaiyu Zang; L. Jason Lu; Amy S. Shah
Diabetes June 2016, Vol.65, 2100. doi:https://doi.org/10.2337/db16-er07
Issues and Events
E-Letters: Comments and Responses
Response to Comment on Salomon et al. Gestational Diabetes Mellitus Is Associated With Changes in the Concentration and Bioactivity of Placenta-Derived Exosomes in Maternal Circulation Across Gestation. Diabetes 2016;65:598–609
Diabetes June 2016, Vol.65, e26-e27. doi:https://doi.org/10.2337/dbi16-0016
