Skip Nav Destination
Issues
1 October 2017
-
Cover Image
Cover Image
On the cover: Immunofluorescence staining of Nox5 (red) and SM22-α (green) on human kidney biopsy obtained from an individual with diabetes showing colocalization of Nox5 (yellow) in the vascular smooth muscle cells including glomerular mesangial cells (magnification ×20). Image courtesy of Jay C. Jha, Baker IDI Heart and Diabetes Institute and Monash University, Melbourne, Australia. His article, “NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy,” appears in this issue of Diabetes (p. 2691).
Authors are invited to submit images for use on the cover of Diabetes. Black and white or color photographic or photomicrographic images are acceptable. Cover image submission and selection is completely independent of article submission and the peer-review process. Click here for more information. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes September 2017, Vol.66, 2533-2534. doi:https://doi.org/10.2337/db17-ti10
Commentaries
Sirtuin 6 Builds a Wall Against Inflammation, Trumping Diabetes
Diabetes September 2017, Vol.66, 2535-2537. doi:https://doi.org/10.2337/dbi17-0025
New Tricks for Nrf2: Therapeutic Targeting to Restore BK-β1 Expression?
Diabetes September 2017, Vol.66, 2538-2540. doi:https://doi.org/10.2337/dbi17-0024
Metabolism
Bone Regulates Browning and Energy Metabolism Through Mature Osteoblast/Osteocyte PPARγ Expression
Diabetes July 2017, Vol.66, 2541-2554. doi:https://doi.org/10.2337/db17-0116
Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity
Yuanqing Gao; Clarita Layritz; Beata Legutko; Thomas O. Eichmann; Elise Laperrousaz; Valentine S. Moullé; Celine Cruciani-Guglielmacci; Christophe Magnan; Serge Luquet; Stephen C. Woods; Robert H. Eckel; Chun-Xia Yi; Cristina Garcia-Caceres; Matthias H. Tschöp
Diabetes July 2017, Vol.66, 2555-2563. doi:https://doi.org/10.2337/db16-1278
Hepatic but Not Extrahepatic Insulin Clearance Is Lower in African American Than in European American Women
Diabetes July 2017, Vol.66, 2564-2570. doi:https://doi.org/10.2337/db17-0413
DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver
Xin Tong; Deqiang Zhang; Nicholas Charney; Ethan Jin; Kyle VanDommelen; Kenneth Stamper; Neil Gupta; Johnny Saldate; Lei Yin
Diabetes August 2017, Vol.66, 2571-2582. doi:https://doi.org/10.2337/db16-1600
Opposite Regulation of Insulin Sensitivity by Dietary Lipid Versus Carbohydrate Excess
Anne-Marie Lundsgaard; Kim A. Sjøberg; Louise D. Høeg; Jacob Jeppesen; Andreas B. Jordy; Annette K. Serup; Andreas M. Fritzen; Henriette Pilegaard; Lene S. Myrmel; Lise Madsen; Jørgen F.P. Wojtaszewski; Erik A. Richter; Bente Kiens
Diabetes August 2017, Vol.66, 2583-2595. doi:https://doi.org/10.2337/db17-0046
Obesity Studies
Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance
Su-Yeon Lee; Hui-Young Lee; Jae-Hwi Song; Goon-Tae Kim; Suwon Jeon; Yoo-Jeong Song; Jae Sung Lee; Jang-Ho Hur; Hyun Hee Oh; Shi-Young Park; Soon-Mi Shim; Hyun Joo Yoo; Byung Cheon Lee; Xian-Cheng Jiang; Cheol Soo Choi; Tae-Sik Park
Diabetes July 2017, Vol.66, 2596-2609. doi:https://doi.org/10.2337/db16-1232
Islet Studies
Recruitment of Epac2A to Insulin Granule Docking Sites Regulates Priming for Exocytosis
Diabetes July 2017, Vol.66, 2610-2622. doi:https://doi.org/10.2337/db17-0050
Thyroid Hormone Coordinates Pancreatic Islet Maturation During the Zebrafish Larval-to-Juvenile Transition to Maintain Glucose Homeostasis
Diabetes July 2017, Vol.66, 2623-2635. doi:https://doi.org/10.2337/db16-1476
Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation
Andrew T. Templin; Tanya Samarasekera; Daniel T. Meier; Meghan F. Hogan; Mahnaz Mellati; Michael T. Crow; Richard N. Kitsis; Sakeneh Zraika; Rebecca L. Hull; Steven E. Kahn
Diabetes July 2017, Vol.66, 2636-2645. doi:https://doi.org/10.2337/db16-1352
SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis–Related Diabetes
Xiangwei Xiao; Shane Fischbach; Tina Zhang; Congde Chen; Qingfeng Sheng; Ray Zimmerman; Sneha Patnaik; Joseph Fusco; Yungching Ming; Ping Guo; Chiyo Shiota; Krishna Prasadan; Nupur Gangopadhyay; Sohail Z. Husain; Henry Dong; George K. Gittes
Diabetes August 2017, Vol.66, 2646-2658. doi:https://doi.org/10.2337/db17-0537
Pathophysiology
Myeloid Sirtuin 6 Deficiency Causes Insulin Resistance in High-Fat Diet–Fed Mice by Eliciting Macrophage Polarization Toward an M1 Phenotype
Youngyi Lee; Sun-O Ka; Hye-Na Cha; Yu-Na Chae; Mi-Kyung Kim; So-Young Park; Eun Ju Bae; Byung-Hyun Park
Diabetes June 2017, Vol.66, 2659-2668. doi:https://doi.org/10.2337/db16-1446
Low-Dose Persistent Organic Pollutants Impair Insulin Secretory Function of Pancreatic β-Cells: Human and In Vitro Evidence
Yu-Mi Lee; Chae-Myeong Ha; Se-A Kim; Themis Thoudam; Young-Ran Yoon; Dae-Jung Kim; Hyeon-Chang Kim; Hyo-Bang Moon; Sungmi Park; In-Kyu Lee; Duk-Hee Lee
Diabetes July 2017, Vol.66, 2669-2680. doi:https://doi.org/10.2337/db17-0188
Complications
NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy
Jay C. Jha; Claudine Banal; Jun Okabe; Stephen P. Gray; Thushan Hettige; Bryna S.M. Chow; Vicki Thallas-Bonke; Lisanne De Vos; Chet E. Holterman; Melinda T. Coughlan; David A. Power; Alison Skene; Elif I. Ekinci; Mark E. Cooper; Rhian M. Touyz; Chris R. Kennedy; Karin Jandeleit-Dahm
Diabetes July 2017, Vol.66, 2691-2703. doi:https://doi.org/10.2337/db16-1585
Genetics / Genomes / Proteomics / Metabolomics
Genetic Susceptibility, Change in Physical Activity, and Long-term Weight Gain
Tiange Wang; Tao Huang; Yoriko Heianza; Dianjianyi Sun; Yan Zheng; Wenjie Ma; Majken K. Jensen; Jae H. Kang; Janey L. Wiggs; Louis R. Pasquale; Eric B. Rimm; JoAnn E. Manson; Frank B. Hu; Walter C. Willett; Lu Qi
Diabetes July 2017, Vol.66, 2704-2712. doi:https://doi.org/10.2337/db17-0071
Structural Basis and Genotype–Phenotype Correlations of INSR Mutations Causing Severe Insulin Resistance
Jun Hosoe; Hiroko Kadowaki; Fuyuki Miya; Katsuya Aizu; Tomoyuki Kawamura; Ichiro Miyata; Kenichi Satomura; Takeru Ito; Kazuo Hara; Masaki Tanaka; Hiroyuki Ishiura; Shoji Tsuji; Ken Suzuki; Minaka Takakura; Keith A. Boroevich; Tatsuhiko Tsunoda; Toshimasa Yamauchi; Nobuhiro Shojima; Takashi Kadowaki
Diabetes August 2017, Vol.66, 2713-2723. doi:https://doi.org/10.2337/db17-0301
Errata
Erratum. Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese. Diabetes 2013;62:2747–2751
Jetro J. Tuulari; Henry K. Karlsson; Jussi Hirvonen; Jarna C. Hannukainen; Marco Bucci; Mika Helmiö; Jari Ovaska; Minna Soinio; Paulina Salminen; Nina Savisto; Lauri Nummenmaa; Pirjo Nuutila
Diabetes August 2017, Vol.66, 2724. doi:https://doi.org/10.2337/db17-er10a
Erratum. Association Between Long-term Exposure to Air Pollution and Biomarkers Related to Insulin Resistance, Subclinical Inflammation, and Adipokines. Diabetes 2016;65:3314–3326
Kathrin Wolf; for the KORA-Study Group; Anita Popp; for the KORA-Study Group; Alexandra Schneider; for the KORA-Study Group; Susanne Breitner; for the KORA-Study Group; Regina Hampel; for the KORA-Study Group; Wolfgang Rathmann; for the KORA-Study Group; Christian Herder; for the KORA-Study Group; Michael Roden; for the KORA-Study Group; Wolfgang Koenig; for the KORA-Study Group; Christa Meisinger; for the KORA-Study Group; Annette Peters; for the KORA-Study Group
Diabetes August 2017, Vol.66, 2725. doi:https://doi.org/10.2337/db17-er10b
