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January 2018
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Cover Image
Cover Image
On the cover: Islet clusters derived from nuclear transfer embryonic stem cells reprogrammed from a skin fibroblast of a patient with type 1 diabetes. Image courtesy of Lina Sui, Naomi Berrie Diabetes Center and Department of Pediatrics, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY. Her article, “β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells,” appears in this issue of Diabetes (p. 26).
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ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes December 2017, Vol.67, 1-2. doi:https://doi.org/10.2337/db18-ti01
Perspectives in Diabetes
Diabetes in China: Epidemiology and Genetic Risk Factors and Their Clinical Utility in Personalized Medication
Diabetes December 2017, Vol.67, 3-11. doi:https://doi.org/10.2337/dbi17-0013
The Adiponectin Paradox for All-Cause and Cardiovascular Mortality
Diabetes December 2017, Vol.67, 12-22. doi:https://doi.org/10.2337/dbi17-0016
Commentary
SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis
Diabetes December 2017, Vol.67, 23-25. doi:https://doi.org/10.2337/dbi17-0042
Technological Advances
β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells
Lina Sui; Nichole Danzl; Sean R. Campbell; Ryan Viola; Damian Williams; Yuan Xing; Yong Wang; Neil Phillips; Greg Poffenberger; Bjarki Johannesson; Jose Oberholzer; Alvin C. Powers; Rudolph L. Leibel; Xiaojuan Chen; Megan Sykes; Dieter Egli
Diabetes September 2017, Vol.67, 26-35. doi:https://doi.org/10.2337/db17-0120
Metabolism
IL-6–Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion
Stephan Wueest; Céline I. Laesser; Marianne Böni-Schnetzler; Flurin Item; Fabrizio C. Lucchini; Marcela Borsigova; Werner Müller; Marc Y. Donath; Daniel Konrad
Diabetes October 2017, Vol.67, 36-45. doi:https://doi.org/10.2337/db17-0637
Signal Transduction
SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation
Jin Cao; Yi Yu; Zhengmao Zhang; Xi Chen; Zhaoyong Hu; Qiang Tong; Jiang Chang; Xin-Hua Feng; Xia Lin
Diabetes August 2017, Vol.67, 46-57. doi:https://doi.org/10.2337/db17-0546
Islet Studies
Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors
Ka-Cheuk Liu; Gunter Leuckx; Daisuke Sakano; Philip A. Seymour; Charlotte L. Mattsson; Linn Rautio; Willem Staels; Yannick Verdonck; Palle Serup; Shoen Kume; Harry Heimberg; Olov Andersson
Diabetes October 2017, Vol.67, 58-70. doi:https://doi.org/10.2337/db16-1587
Mitochondrial Protein UCP2 Controls Pancreas Development
Benjamin Broche; Selma Ben Fradj; Esther Aguilar; Tiphaine Sancerni; Matthieu Bénard; Fatna Makaci; Claire Berthault; Raphaël Scharfmann; Marie-Clotilde Alves-Guerra; Bertrand Duvillié
Diabetes October 2017, Vol.67, 78-84. doi:https://doi.org/10.2337/db17-0118
Pathophysiology
Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle
Diabetes November 2017, Vol.67, 85-97. doi:https://doi.org/10.2337/db17-0367
Complications
Negative Regulation of TRPA1 by AMPK in Primary Sensory Neurons as a Potential Mechanism of Painful Diabetic Neuropathy
Shenglan Wang; Kimiko Kobayashi; Yoko Kogure; Hiroki Yamanaka; Satoshi Yamamoto; Hideshi Yagi; Koichi Noguchi; Yi Dai
Diabetes October 2017, Vol.67, 98-109. doi:https://doi.org/10.2337/db17-0503
Deletion of the Akt/mTORC1 Repressor REDD1 Prevents Visual Dysfunction in a Rodent Model of Type 1 Diabetes
William P. Miller; Chen Yang; Maria L. Mihailescu; Joshua A. Moore; Weiwei Dai; Alistair J. Barber; Michael D. Dennis
Diabetes October 2017, Vol.67, 110-119. doi:https://doi.org/10.2337/db17-0728
Evidence That Differences in Fructosamine-3-Kinase Activity May Be Associated With the Glycation Gap in Human Diabetes
Simon J. Dunmore; Amr S. Al-Derawi; Ananth U. Nayak; Aruna Narshi; Alan M. Nevill; Anne Hellwig; Andrew Majebi; Paul Kirkham; James E. Brown; Baldev M. Singh
Diabetes October 2017, Vol.67, 131-136. doi:https://doi.org/10.2337/db17-0441
Genetics / Genomes / Proteomics / Metabolomics
Insights From Molecular Characterization of Adult Patients of Families With Multigenerational Diabetes
Serena Pezzilli; Ornella Ludovico; Tommaso Biagini; Luana Mercuri; Federica Alberico; Eleonora Lauricella; Hamza Dallali; Daniele Capocefalo; Massimo Carella; Elide Miccinilli; Pamela Piscitelli; Maria Giovanna Scarale; Tommaso Mazza; Vincenzo Trischitta; Sabrina Prudente
Diabetes October 2017, Vol.67, 137-145. doi:https://doi.org/10.2337/db17-0867
Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity
Jill M. Norris; Hye-Seung Lee; Brittni Frederiksen; Iris Erlund; Ulla Uusitalo; Jimin Yang; Åke Lernmark; Olli Simell; Jorma Toppari; Marian Rewers; Anette-G. Ziegler; Jin-Xiong She; Suna Onengut-Gumuscu; Wei-Min Chen; Stephen S. Rich; Jouko Sundvall; Beena Akolkar; Jeffrey Krischer; Suvi M. Virtanen; William Hagopian; The TEDDY Study Group
Diabetes October 2017, Vol.67, 146-154. doi:https://doi.org/10.2337/db17-0802
Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study
Diabetes October 2017, Vol.67, 155-164. doi:https://doi.org/10.2337/db16-1229
Erratum
Erratum. Deletion of p66Shc Longevity Gene Protects Against Experimental Diabetic Glomerulopathy by Preventing Diabetes-Induced Oxidative Stress. Diabetes 2006;55:1642–1650
Stefano Menini; Lorena Amadio; Giovanna Oddi; Carlo Ricci; Carlo Pesce; Francesco Pugliese; Marco Giorgio; Enrica Migliaccio; PierGiuseppe Pelicci; Carla Iacobini; Giuseppe Pugliese
Diabetes October 2017, Vol.67, 165. doi:https://doi.org/10.2337/db18-er01a
