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1 December 2018
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Cover Image
Cover Image
On the cover: Islets of Langerhans cells, computer artwork. These cells (pink) of the pancreas release hormones (colored dots) into the blood. Credit: David Mack/Science Source. For further information, please visit www.sciencesource.com.
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ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes November 2018, Vol.67, 2483-2484. doi:https://doi.org/10.2337/db18-ti12
Perspectives in Diabetes
Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis
Diabetes November 2018, Vol.67, 2485-2493. doi:https://doi.org/10.2337/dbi18-0024
Metabolism
CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet
Lin Zhu; Thao Luu; Christopher H. Emfinger; Bryan A. Parks; Jeanne Shi; Elijah Trefts; Fenghua Zeng; Zsuzsanna Kuklenyik; Raymond C. Harris; David H. Wasserman; Sergio Fazio; John M. Stafford
Diabetes September 2018, Vol.67, 2494-2506. doi:https://doi.org/10.2337/db18-0474
Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance
Chris Shannon; Aurora Merovci; Juan Xiong; Devjit Tripathy; Felipe Lorenzo; Donald McClain; Muhammad Abdul-Ghani; Luke Norton; Ralph A. DeFronzo
Diabetes September 2018, Vol.67, 2507-2517. doi:https://doi.org/10.2337/db18-0439
Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects
Chelsea L. Faber; Miles E. Matsen; Kevin R. Velasco; Vincent Damian; Bao Anh Phan; Daniel Adam; Anthony Therattil; Michael W. Schwartz; Gregory J. Morton
Diabetes September 2018, Vol.67, 2518-2529. doi:https://doi.org/10.2337/db18-0380
Paternal Exercise Improves Glucose Metabolism in Adult Offspring
Kristin I. Stanford; Morten Rasmussen; Lisa A. Baer; Adam C. Lehnig; Leslie A. Rowland; Joseph D. White; Kawai So; Ana Luisa De Sousa-Coelho; Michael F. Hirshman; Mary-Elizabeth Patti; Oliver J. Rando; Laurie J. Goodyear
Diabetes November 2018, Vol.67, 2530-2540. doi:https://doi.org/10.2337/db18-0667
Signal Transduction
miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity
Eun-Hee Koh; Natasha Chernis; Pradip K. Saha; Liuling Xiao; David A. Bader; Bokai Zhu; Kimal Rajapakshe; Mark P. Hamilton; Xia Liu; Dimuthu Perera; Xi Chen; Brian York; Michael Trauner; Cristian Coarfa; Mandeep Bajaj; David D. Moore; Tuo Deng; Sean E. McGuire; Sean M. Hartig
Diabetes July 2018, Vol.67, 2541-2553. doi:https://doi.org/10.2337/db17-1378
miRNA Regulation of the Hyperproliferative Phenotype of Vascular Smooth Muscle Cells in Diabetes
Daniele Torella; Claudio Iaconetti; Roberta Tarallo; Fabiola Marino; Giorgio Giurato; Claudia Veneziano; Iolanda Aquila; Mariangela Scalise; Teresa Mancuso; Eleonora Cianflone; Chiara Valeriano; Pina Marotta; Laura Tammè; Carla Vicinanza; Ferdinando C. Sasso; Domenico Cozzolino; Michele Torella; Alessandro Weisz; Ciro Indolfi
Diabetes September 2018, Vol.67, 2554-2568. doi:https://doi.org/10.2337/db17-1434
Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin–Axin2–GSK3β Signaling Pathway
Yuan-Yuan Xie; Chun-Li Mo; Yi-Huang Cai; Wen-Jie Wang; Xin-Xin Hong; Kun-Kun Zhang; Qing-Feng Liu; Yun-Jia Liu; Jing-Jing Hong; Ting He; Zhong-Zheng Zheng; Wei Mo; Bo-An Li
Diabetes October 2018, Vol.67, 2569-2584. doi:https://doi.org/10.2337/db18-0311
Obesity Studies
Obesity-Associated miR-199a/214 Cluster Inhibits Adipose Browning via PRDM16–PGC-1α Transcriptional Network
Linyun He; Mowei Tang; Ting Xiao; Hailan Liu; Wei Liu; Guangdi Li; Feng Zhang; Yalun Xiao; Zhiguang Zhou; Feng Liu; Fang Hu
Diabetes October 2018, Vol.67, 2585-2600. doi:https://doi.org/10.2337/db18-0626
Islet Studies
Glucagon-Like Peptide 1 Increases β-Cell Regeneration by Promoting α- to β-Cell Transdifferentiation
Diabetes September 2018, Vol.67, 2601-2614. doi:https://doi.org/10.2337/db18-0155
Haploinsufficiency of Insm1 Impairs Postnatal Baseline β-Cell Mass
Weihua Tao; Yao Zhang; Lijuan Ma; Chujun Deng; Hualin Duan; Xuehua Liang; Rui Liao; Shaoqiang Lin; Tao Nie; Wanqun Chen; Cunchuan Wang; Carmen Birchmeier; Shiqi Jia
Diabetes September 2018, Vol.67, 2615-2625. doi:https://doi.org/10.2337/db17-1330
Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass
Diabetes October 2018, Vol.67, 2626-2639. doi:https://doi.org/10.2337/db18-0259
Immunology and Transplantation
Increase Functional β-Cell Mass in Subcutaneous Alginate Capsules With Porcine Prenatal Islet Cells but Loss With Human Adult Islet Cells
Ines De Mesmaeker; Thomas Robert; Krista G. Suenens; Geert M. Stangé; Freya Van Hulle; Zhidong Ling; Peter Tomme; Daniel Jacobs-Tulleneers-Thevissen; Bart Keymeulen; Daniel G. Pipeleers
Diabetes October 2018, Vol.67, 2640-2649. doi:https://doi.org/10.2337/db18-0709
Pathophysiology
Reduced GLP-1 Secretion at 30 Minutes After a 75-g Oral Glucose Load Is Observed in Gestational Diabetes Mellitus: A Prospective Cohort Study
Nithya Sukumar; Christos Bagias; Ilona Goljan; Yonas Weldeselassie; Seley Gharanei; Bee K. Tan; Jens J. Holst; Ponnusamy Saravanan
Diabetes September 2018, Vol.67, 2650-2656. doi:https://doi.org/10.2337/db18-0254
Complications
Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis
Eoin P. Brennan; Muthukumar Mohan; Aaron McClelland; Monica de Gaetano; Christos Tikellis; Mariam Marai; Daniel Crean; Aozhi Dai; Ophelie Beuscart; Sinda Derouiche; Stephen P. Gray; Raelene Pickering; Sih Min Tan; Molly Godson-Treacy; Stephen Sheehan; Joseph F. Dowdall; Mary Barry; Orina Belton; Syed Tasadaque Ali-Shah; Patrick J. Guiry; Karin Jandeleit-Dahm; Mark E. Cooper; Catherine Godson; Phillip Kantharidis
Diabetes September 2018, Vol.67, 2657-2667. doi:https://doi.org/10.2337/db17-1317
Histone H3 Serine 10 Phosphorylation Facilitates Endothelial Activation in Diabetic Kidney Disease
Tamadher A. Alghamdi; Sri N. Batchu; Mitchell J. Hadden; Veera Ganesh Yerra; Youan Liu; Bridgit B. Bowskill; Suzanne L. Advani; Laurette Geldenhuys; Ferhan S. Siddiqi; Syamantak Majumder; Andrew Advani
Diabetes September 2018, Vol.67, 2668-2681. doi:https://doi.org/10.2337/db18-0124
FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing
Mohammed A. Alharbi; Citong Zhang; Chanyi Lu; Tatyana N. Milovanova; Leah Yi; Je Dong Ryu; Hongli Jiao; Guangyu Dong; J. Patrick O’Connor; Dana T. Graves
Diabetes October 2018, Vol.67, 2682-2694. doi:https://doi.org/10.2337/db18-0340
Insulin Resistance and Vulnerability to Cardiac Ischemia
Tomas Jelenik; Ulrich Flögel; Elisa Álvarez-Hernández; Daniel Scheiber; Elric Zweck; Zhaoping Ding; Maik Rothe; Lucia Mastrototaro; Vivien Kohlhaas; Jörg Kotzka; Birgit Knebel; Dirk Müller-Wieland; Sarah Moellendorf; Axel Gödecke; Malte Kelm; Ralf Westenfeld; Michael Roden; Julia Szendroedi
Diabetes September 2018, Vol.67, 2695-2702. doi:https://doi.org/10.2337/db18-0449
Genetics / Genomes / Proteomics / Metabolomics
Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus
Camille E. Powe; Michael Nodzenski; Octavious Talbot; Catherine Allard; Catherine Briggs; Marysa V. Leya; Patrice Perron; Luigi Bouchard; Jose C. Florez; Denise M. Scholtens; William L. Lowe, Jr.; Marie-France Hivert
Diabetes September 2018, Vol.67, 2703-2709. doi:https://doi.org/10.2337/db18-0203
Erratum
Erratum. The Adiponectin Paradox for All-Cause and Cardiovascular Mortality. Diabetes 2018;67:12–22
Diabetes October 2018, Vol.67, 2710. doi:https://doi.org/10.2337/db18-er12a