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February 2018
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Cover Image
Cover Image
On the cover: Polarized light micrograph of cortisol crystals. Magnification: ×40 at 4 × 5 in. Credit: Alfred Pasieka/Science Source. For further information, please visit www.sciencesource.com. This issue of Diabetes includes the article “Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion,” by Fine et al. (p. 278).
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ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes January 2018, Vol.67, 167-168. doi:https://doi.org/10.2337/db18-ti02
Scientific Achievement Award Lecture
Cellular Energy Sensing and Metabolism—Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture
Diabetes January 2018, Vol.67, 169-179. doi:https://doi.org/10.2337/dbi17-0039
Commentary
Technological Advances
In Vivo Visualization of β-Cells by Targeting of GPR44
Olof Eriksson; Peter Johnström; Zsolt Cselenyi; Mahabuba Jahan; Ram K. Selvaraju; Marianne Jensen-Waern; Akihiro Takano; Maria Sörhede Winzell; Christer Halldin; Stanko Skrtic; Olle Korsgren
Diabetes December 2017, Vol.67, 182-192. doi:https://doi.org/10.2337/db17-0764
Metabolism
S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy
Qingwen Qian; Zeyuan Zhang; Allyson Orwig; Songhai Chen; Wen-Xing Ding; Yanji Xu; Ryan C. Kunz; Nicholas R.L. Lind; Jonathan S. Stamler; Ling Yang
Diabetes October 2017, Vol.67, 193-207. doi:https://doi.org/10.2337/db17-0223
Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling
Kevin C. Corbit; João Paulo G. Camporez; Lia R. Edmunds; Jennifer L. Tran; Nicholas B. Vera; Derek M. Erion; Rahul C. Deo; Rachel J. Perry; Gerald I. Shulman; Michael J. Jurczak; Ethan J. Weiss
Diabetes December 2017, Vol.67, 208-221. doi:https://doi.org/10.2337/db17-0524
Regulation of Lipolytic Response and Energy Balance by Melanocortin 2 Receptor Accessory Protein (MRAP) in Adipocytes
Diabetes December 2017, Vol.67, 222-234. doi:https://doi.org/10.2337/db17-0862
Obesity Studies
Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue
Hui Zhao; Qianwen Shang; Zhenzhen Pan; Yang Bai; Zequn Li; Huiying Zhang; Qiu Zhang; Chun Guo; Lining Zhang; Qun Wang
Diabetes November 2017, Vol.67, 235-247. doi:https://doi.org/10.2337/db17-0356
Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life
Diabetes December 2017, Vol.67, 248-255. doi:https://doi.org/10.2337/db17-1156
Islet Studies
miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function
Diabetes November 2017, Vol.67, 256-264. doi:https://doi.org/10.2337/db17-0506
Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion
Nicholas H.F. Fine; Craig L. Doig; Yasir S. Elhassan; Nicholas C. Vierra; Piero Marchetti; Marco Bugliani; Rita Nano; Lorenzo Piemonti; Guy A. Rutter; David A. Jacobson; Gareth G. Lavery; David J. Hodson
Diabetes December 2017, Vol.67, 278-290. doi:https://doi.org/10.2337/db16-1356
Complications
Photobiomodulation Inhibits Long-term Structural and Functional Lesions of Diabetic Retinopathy
Diabetes November 2017, Vol.67, 291-298. doi:https://doi.org/10.2337/db17-0803
Pharmacology and Therapeutics
Engineering Glucose Responsiveness Into Insulin
Niels C. Kaarsholm; Songnian Lin; Lin Yan; Theresa Kelly; Margaret van Heek; James Mu; Margaret Wu; Ge Dai; Yan Cui; Yonghua Zhu; Ester Carballo-Jane; Vijay Reddy; Peter Zafian; Pei Huo; Shuai Shi; Valentyn Antochshuk; Aimie Ogawa; Franklin Liu; Sandra C. Souza; Wolfgang Seghezzi; Joseph L. Duffy; Mark Erion; Ravi P. Nargund; David E. Kelley
Diabetes November 2017, Vol.67, 299-308. doi:https://doi.org/10.2337/db17-0577
Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery
Diabetes December 2017, Vol.67, 309-320. doi:https://doi.org/10.2337/db17-0607
The Synthetic Microneurotrophin BNN27 Affects Retinal Function in Rats With Streptozotocin-Induced Diabetes
Ruth Ibán-Arias; Silvia Lisa; Niki Mastrodimou; Despina Kokona; Emmanuil Koulakis; Panagiota Iordanidou; Antonis Kouvarakis; Myrto Fothiadaki; Sofia Papadogkonaki; Aggeliki Sotiriou; Haralambos E. Katerinopoulos; Achille Gravanis; Ioannis Charalampopoulos; Kyriaki Thermos
Diabetes December 2017, Vol.67, 321-333. doi:https://doi.org/10.2337/db17-0391
Genetics / Genomes / Proteomics / Metabolomics
A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study
Aino Latva-Rasku; Miikka-Juhani Honka; Alena Stančáková; Heikki A. Koistinen; Johanna Kuusisto; Li Guan; Alisa K. Manning; Heather Stringham; Anna L. Gloyn; Cecilia M. Lindgren; T2D-GENES Consortium; Francis S. Collins; Karen L. Mohlke; Laura J. Scott; Tomi Karjalainen; Lauri Nummenmaa; Michael Boehnke; Pirjo Nuutila; Markku Laakso
Diabetes November 2017, Vol.67, 334-342. doi:https://doi.org/10.2337/db17-1142
Erratum
Erratum. Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes 2017;66:272–286
Kristina M. Mueller; Kerstin Hartmann; Doris Kaltenecker; Sabine Vettorazzi; Mandy Bauer; Lea Mauser; Sabine Amann; Sigrid Jall; Katrin Fischer; Harald Esterbauer; Timo D. Müller; Matthias H. Tschöp; Christoph Magnes; Johannes Haybaeck; Thomas Scherer; Natalie Bordag; Jan P. Tuckermann; Richard Moriggl
Diabetes November 2017, Vol.67, 343-344. doi:https://doi.org/10.2337/db18-er02a
Expressions of Concern
Expression of Concern. The IR1152 Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49:1194–1202. DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978
Matilde Caruso; Claudia Miele; Andrea Oliva; Gerolama Condorelli; Francesco Oriente; Gabriele Riccardi; Brunella Capaldo; Francesca Fiory; Domenico Accili; Pietro Formisano; Francesco Beguinot
Diabetes November 2017, Vol.67, 345. doi:https://doi.org/10.2337/db17-ec2017a
Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50:1244–1252. DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323
Gerolama Condorelli; Giovanni Vigliotta; Alessandra Trencia; Maria Alessandra Maitan; Matilde Caruso; Claudia Miele; Francesco Oriente; Stefania Santopietro; Pietro Formisano; Francesco Beguinot
Diabetes November 2017, Vol.67, 345-346. doi:https://doi.org/10.2337/db17-ec2017b
Expression of Concern. Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase. Diabetes 2011;60:138–147. DOI: 10.2337/db10-0860. PMID: 20864515
Francesco Oriente; Salvatore Iovino; Serena Cabaro; Angela Cassese; Elena Longobardi; Claudia Miele; Paola Ungaro; Pietro Formisano; Francesco Blasi; Francesco Beguinot
Diabetes November 2017, Vol.67, 346-347. doi:https://doi.org/10.2337/db17-ec2017c
