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1 March 2018
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Cover Image
Cover Image
On the cover: Colored scanning electron micrograph of enzyme-secreting cells in the pancreas. Magnification: ×350 at 6 × 7 cm. Credit: Susumu Nishinaga/Science Source. For further information, please visit www.sciencesource.com
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ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Diabetes February 2018, Vol.67, 349-350. doi:https://doi.org/10.2337/db18-ti03
Perspectives in Diabetes
Closing in on the Mechanisms of Pulsatile Insulin Secretion
Diabetes February 2017, Vol.67, 351-359. doi:https://doi.org/10.2337/dbi17-0004
Metabolism
Ligand-Dependent Interaction of PPARδ With T-Cell Protein Tyrosine Phosphatase 45 Enhances Insulin Signaling
Taesik Yoo; Sun Ah Ham; Won Jin Lee; Seon In Hwang; Jin-A Park; Jung Seok Hwang; Jinwoo Hur; Ho-Chul Shin; Sung Gu Han; Chi-Ho Lee; Dong Wook Han; Kyung Shin Paek; Han Geuk Seo
Diabetes December 2017, Vol.67, 360-371. doi:https://doi.org/10.2337/db17-0499
Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase
Lotta E. Andersson; Liliya Shcherbina; Mahmoud Al-Majdoub; Neelanjan Vishnu; Claudia Balderas Arroyo; Jonathan Aste Carrara; Claes B. Wollheim; Malin Fex; Hindrik Mulder; Nils Wierup; Peter Spégel
Diabetes December 2017, Vol.67, 372-384. doi:https://doi.org/10.2337/db16-1441
Signal Transduction
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells
Teresa Buenaventura; Nisha Kanda; Phoebe C. Douzenis; Ben Jones; Stephen R. Bloom; Pauline Chabosseau; Ivan R. Corrêa, Jr.; Domenico Bosco; Lorenzo Piemonti; Piero Marchetti; Paul R. Johnson; A.M. James Shapiro; Guy A. Rutter; Alejandra Tomas
Diabetes December 2017, Vol.67, 385-399. doi:https://doi.org/10.2337/db17-0639
Obesity Studies
Sucrose Nonfermenting-Related Kinase Regulates Both Adipose Inflammation and Energy Homeostasis in Mice and Humans
Jie Li; Bin Feng; Yaohui Nie; Ping Jiao; Xiaochen Lin; Mengna Huang; Ran An; Qin He; Huilin Emily Zhou; Arthur Salomon; Kirsten S. Sigrist; Zhidan Wu; Simin Liu; Haiyan Xu
Diabetes January 2018, Vol.67, 400-411. doi:https://doi.org/10.2337/db17-0745
Islet Studies
The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation
Chi Kin Wong; Adam K. Wade-Vallance; Dan S. Luciani; Paul K. Brindle; Francis C. Lynn; William T. Gibson
Diabetes December 2017, Vol.67, 412-422. doi:https://doi.org/10.2337/db17-0237
SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival
Jonàs Juan-Mateu; Maria Inês Alvelos; Jean-Valéry Turatsinze; Olatz Villate; Esther Lizarraga-Mollinedo; Fabio Arturo Grieco; Laura Marroquí; Marco Bugliani; Piero Marchetti; Décio L. Eizirik
Diabetes December 2017, Vol.67, 423-436. doi:https://doi.org/10.2337/db17-0736
Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner
Lina Sakhneny; Eleonor Rachi; Alona Epshtein; Helen C. Guez; Shane Wald-Altman; Michal Lisnyansky; Laura Khalifa-Malka; Adina Hazan; Daria Baer; Avi Priel; Miguel Weil; Limor Landsman
Diabetes December 2017, Vol.67, 437-447. doi:https://doi.org/10.2337/db17-0697
GATA6 Controls Insulin Biosynthesis and Secretion in Adult β-Cells
Laura Villamayor; Elisa Rodríguez-Seguel; Raquel Araujo; Manuel Carrasco; Eva Bru-Tarí; José Manuel Mellado-Gil; Benoit R. Gauthier; Paola Martinelli; Iván Quesada; Bernat Soria; Franz Martín; David A. Cano; Anabel Rojas
Diabetes December 2017, Vol.67, 448-460. doi:https://doi.org/10.2337/db17-0364
MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells
Paul Richards; Latif Rachdi; Masaya Oshima; Piero Marchetti; Marco Bugliani; Mathieu Armanet; Catherine Postic; Sandra Guilmeau; Raphael Scharfmann
Diabetes December 2017, Vol.67, 461-472. doi:https://doi.org/10.2337/db17-0595
Immunology and Transplantation
Highly Angiogenic, Nonthrombogenic Bone Marrow Mononuclear Cell–Derived Spheroids in Intraportal Islet Transplantation
Bae Jun Oh; Sang-Man Jin; Yoonha Hwang; Jin Myung Choi; Han-Sin Lee; Gyuri Kim; Geunsoo Kim; Hyo Jun Park; Pilhan Kim; Sung Joo Kim; Jae Hyeon Kim
Diabetes January 2018, Vol.67, 473-485. doi:https://doi.org/10.2337/db17-0705
Pathophysiology
Excitatory GABAergic Action and Increased Vasopressin Synthesis in Hypothalamic Magnocellular Neurosecretory Cells Underlie the High Plasma Level of Vasopressin in Diabetic Rats
Young-Beom Kim; Woong Bin Kim; Won Woo Jung; Xiangyan Jin; Yoon Sik Kim; Byoungjae Kim; Hee Chul Han; Gene D. Block; Christopher S. Colwell; Yang In Kim
Diabetes December 2017, Vol.67, 486-495. doi:https://doi.org/10.2337/db17-1042
Defective Amplifying Pathway of β-Cell Secretory Response to Glucose in Type 2 Diabetes: Integrated Modeling of In Vitro and In Vivo Evidence
Diabetes December 2017, Vol.67, 496-506. doi:https://doi.org/10.2337/db17-1039
Complications
Metallothionein Preserves Akt2 Activity and Cardiac Function via Inhibiting TRB3 in Diabetic Hearts
Junlian Gu; Xiaoqing Yan; Xiaozhen Dai; Yuehui Wang; Qian Lin; Jian Xiao; Shanshan Zhou; Jian Zhang; Kai Wang; Jun Zeng; Ying Xin; Michelle T. Barati; Chi Zhang; Yang Bai; Yan Li; Paul N. Epstein; Kupper A. Wintergerst; Xiaokun Li; Yi Tan; Lu Cai
Diabetes October 2017, Vol.67, 507-517. doi:https://doi.org/10.2337/db17-0219
DPP-4 Inhibitors Improve Diabetic Wound Healing via Direct and Indirect Promotion of Epithelial-Mesenchymal Transition and Reduction of Scarring
Min Long; Leiqin Cai; Wenjie Li; Linlin Zhang; Shaodong Guo; Rui Zhang; Yi Zheng; Xiufei Liu; Min Wang; Xianli Zhou; Hui Wang; Xing Li; Ling Li; Zhiming Zhu; Gangyi Yang; Hongting Zheng
Diabetes December 2017, Vol.67, 518-531. doi:https://doi.org/10.2337/db17-0934
Errata
Erratum. Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes. Diabetes 2013;62:3224–3231
E. Jennifer Weil; Gudeta Fufaa; Lois I. Jones; Tracy Lovato; Kevin V. Lemley; Robert L. Hanson; William C. Knowler; Peter H. Bennett; Berne Yee; Bryan D. Myers; Robert G. Nelson
Diabetes January 2018, Vol.67, 532. doi:https://doi.org/10.2337/db18-er03a
Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316–2322
Matthew B. Johnson; Elisa De Franco; Hana Lango Allen; Aisha Al Senani; Nancy Elbarbary; Zeynep Siklar; Merih Berberoglu; Zineb Imane; Alireza Haghighi; Zahra Razavi; Irfan Ullah; Saif Alyaarubi; Daphne Gardner; Sian Ellard; Andrew T. Hattersley; Sarah E. Flanagan
Diabetes January 2018, Vol.67, 532. doi:https://doi.org/10.2337/db18-er03b
