Issues

On the cover: Electron microscopy of mouse exocrine and endocrine cells reveals differences in the cellular architecture of acinar, β-, α-, and γ-cells. A large acinar cell is seen in the top right quadrant, and α-, β-, and γ-cells are seen in the bottom left quadrant. The large nucleus, dense endoplasmic reticulum network, and sparse distribution of mitochondria in the acinar cell are striking in comparison with those in endocrine cells. Image courtesy of Rafael Arrojo e Drigo, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee. The article “Probing β-Cell Biology in Space and Time” appears in this issue of Diabetes, p. 2163.

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