On the cover: Representative light microscopy image of glial fibrillary acidic protein (GFAP) immunoreactivity in the retina of a diabetic nontreated Sprague-Dawley rat. Two weeks after the induction of diabetes by streptozotocin administration, GFAP is significantly upregulated in the diabetic rat retina, an indication of increased macroglia activation. Overactivation of macroglia is associated with the early events of diabetes leading to the development of diabetic retinopathy. Image courtesy of Stavroula Dionysopoulou, Department of Pharmacology, School of Medicine, University of Crete, Heraklion, Crete, Greece. The article “Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy” appears in this issue of Diabetes (p. 638).
Authors are invited to submit images for use on the cover of Diabetes. Black and white or color photographic or photomicrographic images are acceptable. Cover image submission and selection is completely independent of article submission and the peer-review process.
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