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August 2023
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Cover Image
Cover Image
On the cover: Illustration of fully differentiated murine myotubes exposed to electrical pulse stimulation. During electrical pulse stimulation, myotubes secrete GDF15, which acts on pancreatic β-cells to enhance glucose-stimulated insulin secretion. The original image was generated by Elizabeth R.M. Zunica and graphically enhanced for publication by Kathryn P. Belmont (members of the Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA). The article “GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion” appears in this issue of Diabetes, p. 1070.
Authors are invited to submit images for use on the cover of Diabetes. Black and white or color photographic or photomicrographic images are acceptable. Cover image submission and selection is completely independent of article submission and the peer-review process.
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ISSN 0012-1797
EISSN 1939-327X
In this Issue
In This Issue
In This Issue of Diabetes
Diabetes July 2023, Vol.72, 1043-1044. doi:https://doi.org/10.2337/db23-ti08
Perspectives in Diabetes
Is 14-3-3 the Combination to Unlock New Pathways to Improve Metabolic Homeostasis and β-Cell Function?
Diabetes July 2023, Vol.72, 1045-1054. doi:https://doi.org/10.2337/db23-0094
Commentaries
Unveiling Novel Markers and Modeling Clinical Prediction of Treatment Effects Are Equally Important for Implementing Precision Therapeutics
Diabetes July 2023, Vol.72, 1057-1059. doi:https://doi.org/10.2337/dbi22-0039
Methodology Review
Metabolism
GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion
Hui Zhang; Anny Mulya; Stephan Nieuwoudt; Bolormaa Vandanmagsar; Ruth McDowell; Elizabeth C. Heintz; Elizabeth R.M. Zunica; J. Jason Collier; Nadejda Bozadjieva-Kramer; Randy J. Seeley; Christopher L. Axelrod; John P. Kirwan
Diabetes May 2023, Vol.72, 1070-1082. doi:https://doi.org/10.2337/db22-0019
Obesity Studies
Activation of METTL3 Promotes White Adipose Tissue Beiging and Combats Obesity
Renxiang Xie; Sujun Yan; Xiaoling Zhou; Yunyi Gao; Yu Qian; Jingyu Hou; Zhanghui Chen; Kairan Lai; Xiangwei Gao; Saisai Wei
Diabetes May 2023, Vol.72, 1083-1094. doi:https://doi.org/10.2337/db22-0775
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
Yi Zhong; Yilong Wang; Xiaoguang Li; Haojie Qin; Shu Yan; Caijun Rao; Di Fan; Duqiu Liu; Fei Deng; Yanli Miao; Ling Yang; Kai Huang
Diabetes May 2023, Vol.72, 1095-1111. doi:https://doi.org/10.2337/db22-1016
Islet Studies
β-Cell–Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion
Frédérik Oger; Cyril Bourouh; Marika Elsa Friano; Emilie Courty; Laure Rolland; Xavier Gromada; Maeva Moreno; Charlène Carney; Nabil Rabhi; Emmanuelle Durand; Souhila Amanzougarene; Lionel Berberian; Mehdi Derhourhi; Etienne Blanc; Sarah Anissa Hannou; Pierre-Damien Denechaud; Zohra Benfodda; Patrick Meffre; Lluis Fajas; Julie Kerr-Conte; François Pattou; Philippe Froguel; Benoit Pourcet; Amélie Bonnefond; Patrick Collombat; Jean-Sébastien Annicotte
Diabetes May 2023, Vol.72, 1112-1126. doi:https://doi.org/10.2337/db22-0604
Immunology and Transplantation
Protective Renalase Deficiency in β-Cells Shapes Immune Metabolism and Function in Autoimmune Diabetes
Kevin Bode; Tara MacDonald; Taylor Stewart; Bryhan Mendez; Erica P. Cai; Noelle Morrow; Yu-Chi Lee; Peng Yi; Stephan Kissler
Diabetes May 2023, Vol.72, 1127-1143. doi:https://doi.org/10.2337/db23-0030
Complications
The Antinarcolepsy Drug Modafinil Reverses Hypoglycemia Unawareness and Normalizes Glucose Sensing of Orexin Neurons in Male Mice
Vishwendra Patel; Pallabi Sarkar; Dashiel M. Siegel; Suraj B. Teegala; Pamela R. Hirschberg; Hamad Wajid; Omar Itani; Vanessa H. Routh
Diabetes December 2023, Vol.72, 1144-1153. doi:https://doi.org/10.2337/db22-0639
Astrocyte Glycogen Is a Major Source of Hypothalamic Lactate in Rats With Recurrent Hypoglycemia
Diabetes May 2023, Vol.72, 1154-1160. doi:https://doi.org/10.2337/db22-0902
GENETICS / GENOMES / PROTEOMICS / METABOLOMICS
Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP)
Josephine H. Li; James A. Perry; Kathleen A. Jablonski; Shylaja Srinivasan; Ling Chen; Jennifer N. Todd; Maegan Harden; Josep M. Mercader; Qing Pan; Adem Y. Dawed; Sook Wah Yee; Ewan R. Pearson; Kathleen M. Giacomini; Ayush Giri; Adriana M. Hung; Shujie Xiao; L. Keoki Williams; Paul W. Franks; Robert L. Hanson; Steven E. Kahn; William C. Knowler; Toni I. Pollin; Jose C. Florez; Diabetes Prevention Program Research Group:
Diabetes December 2023, Vol.72, 1161-1172. doi:https://doi.org/10.2337/db22-0702
Errata
Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433–448
Teresa L. Mastracci; Minoti Apte; Laufey T. Amundadottir; Alexandra Alvarsson; Steven Artandi; Melena D. Bellin; Ernesto Bernal-Mizrachi; Alejandro Caicedo; Martha Campbell-Thompson; Zobeida Cruz-Monserrate; Abdelfattah El Ouaamari; Kyle J. Gaulton; Andrea Geisz; Mark O. Goodarzi; Manami Hara; Rebecca L. Hull-Meichle; Alexander Kleger; Alison P. Klein; Janel L. Kopp; Rohit N. Kulkarni; Mandar D. Muzumdar; Anjaparavanda P. Naren; Scott A. Oakes; Søren S. Olesen; Edward A. Phelps; Alvin C. Powers; Cherie L. Stabler; Temel Tirkes; David C. Whitcomb; Dhiraj Yadav; Jing Yong; Norann A. Zaghloul; Stephen J. Pandol; Maike Sander
Diabetes April 2023, Vol.72, 1173. doi:https://doi.org/10.2337/db23-er08
Erratum. Association Between Obesity and Chronic Kidney Disease: Multivariable Mendelian Randomization Analysis and Observational Data From a Bariatric Surgery Cohort. Diabetes 2023;72:496–510
Anthony Nguyen; Rana Khafagy; Yiding Gao; Ameena Meerasa; Delnaz Roshandel; Mehran Anvari; Boxi Lin; David Z.I. Cherney; Michael E. Farkouh; Baiju R. Shah; Andrew D. Paterson; Satya Dash
Diabetes May 2023, Vol.72, 1174. doi:https://doi.org/10.2337/db23-er08a
Statement of Retraction
Statement of Retraction. Timothy Dunn, Yongjin Xu, Sharon Schneider, Susan Gawel, Rajkamal Gopinath, Marvin Berman, and Anthony P. Orzechowski. 1106-P: Real-World Confirmation of the Nonlinear Relationship Between Glucose and Glycated Hemoglobin. Diabetes 2022;71(Suppl.1):1106-P. DOI: 10.2337/db22-1106-P
Diabetes June 2023, Vol.72, 1175. doi:https://doi.org/10.2337/db23-rt08a
Issues and Events
e-LETTERS – COMMENTS AND RESPONSES
Comment on Baranova et al. Causal Associations Between Basal Metabolic Rate and COVID-19. Diabetes 2023;72:149–154
Diabetes July 2023, Vol.72, e6-e7. doi:https://doi.org/10.2337/db23-0175
