Issues

On the cover: Immunofluorescent staining of a mouse pancreatic section showing α-cells (magenta) and β-cells (red) in an islet near the ductal region following treatment with dapagliflozin in diabetic db/db mice. On the top-left part, the presence of β-cells and α-cells near the ductal region implies α-cell and β-cell neogenesis induced by dapagliflozin. Overall, the ductal region and the islet look like a ring. The newborn islet is like a dazzling diamond set in the ring. It shines like a rising star in the treatment of diabetes with islet regeneration. Image courtesy of Yafei Jiang, Jin Yang, Li Xia, Tianpei Hong, and Rui Wei, Department of Endocrinology and Metabolism, Peking University Third Hospital, Beijing, China. The article “Gut Microbiota–Tryptophan Metabolism–GLP-1 Axis Participates in β-Cell Regeneration Induced by Dapagliflozin” appears in this issue of Diabetes (p. 926).