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Brief Report May 22 2025
Smaller Pancreas Volume in Insulin-Dependent Monogenic Diabetes
Jonathan M. Williams; Melissa A. Hilmes; Lisa R. Letourneau-Freiberg; Balamurugan Kandasamy; Demetra Braun; Siri Atma W. Greeley; Louis Philipson; Alvin C. Powers; John Virostko; Daniel J. Moore; Jordan J. Wright
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Islet Studies April 24 2025
A functional and mechanistic explanation for the unique clinical success of the glucokinase activator dorzagliatin for treatment of type 2 diabetes
Jeff Roman; Yue Yuan; Yue Xu; Qiusha Zhu; Shaowen Wu; Fang Zhao; Xue Zhou; Shi Meng; Dongna Han; Kim Sharp; Li Chen; Changhong Li; Nicolai M Doliba
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NIDDK 75th Anniversary Collection April 24 2025
NIDDK: Celebrating 75 Years of Advancing Diabetes Research
William T. Cefalu; Rebecca J. Cerio; Corinne M. Silva; Julie A. Wallace; Griffin P. Rodgers
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NIDDK 75th Anniversary Collection April 24 2025
NIDDK at 75 Years of Age: Great Triumphs but Concerns for Its Longevity
Steven E. Kahn; Cheryl A.M. Anderson; John B. Buse; Elizabeth Selvin; David A. D’Alessio
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Niddk 75th Anniversary Collection April 24 2025
Accelerating Medicines Partnership in Type 2 Diabetes and Common Metabolic Diseases: Collaborating to Maximize the Value of Genetic and Genomic Data
Maria C. Costanzo; Beena Akolkar; Melina Claussnitzer; Jose C. Florez; Anna L. Gloyn; Struan F.A. Grant; Klaus H. Kaestner; Alisa K. Manning; Karen L. Mohlke; Stephen C.J. Parker; Paul M. Titchenell; Miriam S. Udler; Melissa A. Jones; Tania N. Kamphaus; Rachel A. Fischer; Mark I. McCarthy; Melissa R. Miller; Michael Boehnke; AMP T2D Consortium; AMP CMD Consortium; Jason Flannick; Noël P. Burtt
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Niddk 75th Anniversary Collection April 24 2025
Celebrating the Past, Present, and Future of NIDDK-Supported Research Centers Focused on Diabetes, Endocrinology, and Metabolic Diseases
Corinne M. Silva; Pamela L. Thornton; Shavon Artis Dickerson; Thomas L. Eggerman; Maren R. Laughlin; Julie A. Wallace; Mary C. Hanlon-Tilghman; William T. Cefalu
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Niddk 75th Anniversary Collection April 24 2025
Advances in Cell Replacement Therapies for Diabetes
Bernhard J. Hering; Michael R. Rickels; Melena D. Bellin; Jeffrey R. Millman; Alice A. Tomei; Andrés J. García; Haval Shirwan; Cherie L. Stabler; Minglin Ma; Peng Yi; Xunrong Luo; Qizhi Tang; Sabarinathan Ramachandran; Jose Oberholzer; Camillo Ricordi; Timothy J. Kieffer; A.M. James Shapiro
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Niddk 75th Anniversary Collection April 24 2025
Closing the Gap Between Vision and Victory in Type 1 Diabetes: The NIDDK Human Islet Research Network (HIRN) Initiative
Audrey V. Parent; Ashutosh Agarwal; Juan Rene Alvarez-Dominguez; Rafael Arrojo e Drigo; Mark A. Atkinson; Michael A. Brehm; Leonardo M.R. Ferreira; Klaus H. Kaestner; Vira Kravets; Joyce C. Niland; Denis O’Meally; Layla Rouse; Holger A. Russ; Cherie L. Stabler; John S. Kaddis
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Genetics/Genomes/Proteomics/Metabolomics April 24 2025
Paradoxical Maturity-Onset Diabetes of the Young Arising From Loss-of-Function Mutations in ATP-Sensitive Potassium Channels
Rosa Scala; Yunpeng Li; Jian Gao; Nathan W. York; Ranjit Unnikrishnan; Ranjit Mohan Anjana; Viswanathan Mohan; Gopi Sundaramoorthy; Babu Kavitha; Venkatesan Radha; Colin G. Nichols
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Metabolism April 24 2025
Analysis of multiple insulin actions in single muscle fibres from insulin resistant mice reveals selective defect in endogenous GLUT4 translocation
Sebastian Judge; Stewart WC Masson; Søren Madsen; Meg Potter; David E James; James G Burchfield; Alexis Diaz-Vegas
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Genetics/Genomes/Proteomics/Metabolomics April 24 2025
GENETIC VARIATION IN GCKR AND PNPLA3 REGULATE METABOLIC BALANCE ACROSS THE LIVER
Yunyun Ma; Shiqi Zuo; Therlinder Lo; David Phan; Tyler Finley; Adrienne Mackay; Enrique Trigo; Jaana A. Hartiala; Hooman Allayee; Anny H. Xiang; Thomas A. Buchanan; Richard M. Watanabe
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Obesity Studies April 24 2025
Identifying four obesity axes through integrative multi-omics and imaging analysis
Chiemela S. Odoemelam; Afreen Naz; Marjola Thanaj; Elena P Sorokin; Brandon Whitcher; Naveed Sattar; Jimmy D Bell; E Louise Thomas; Madeleine Cule; Hanieh Yaghootkar
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Complications April 24 2025
Targeting tsRNA-1797 alleviates diabetes-induced vascular dysfunction through modulating purine metabolism
Duo Li; Jingyue Zhang; Xiaoyan Han; Lingjie Kong; Ying Zhang; Mudi Yao; Ling Ren; Wan Mu; Qin Jiang; Biao Yan
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Complications April 23 2025
G protein-coupled receptor 35 suppresses oxidative stress response 1 in diabetic wound healing
Hainan Li, MS; Liping Xu, BS; Sai Pranathi Meda Venkata, PhD; Morgan Minjares, BS; Hassan Melhem, PhD; Anjaneyulu Kowluru, PhD; Jan Hendrik Niess, MD; Graeme Milligan, PhD; Jie-Mei Wang, MD PhD
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Complications April 18 2025
Neuroprotective Effect of a Novel Soluble Guanylate Cyclase Activator (sGCa) Runcaciguat in Diabetes and Ischemic Retinopathy
Elia J. Duh; Zhenhua Xu; Hongkwan Cho; Shirley Wu; William Schubert; Carsten Terjung; Fabio Baschiera; Lingli Zhou; Lijuan Wu; Grace Lee; Yangyiran Xie; Qiaoyan Hui; James Guerra; Joseph Mertz; Khaled Nassar
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Obesity Studies April 11 2025
GLP-1-mediated targeting of inflammation corrects obesogenic memory in male mice
Stéphane Léon; Julie Benoit; Samantha Clark; Philippe Zizzari; Bin Yang; Isabelle Dugail; Fatiha Merabtene; Karine Clement; Louise Eygret; Nathalie Dupuy; Jean-Christophe Delpech; Moïra Rossitto; Matthias Mack; Thierry Lesté-Lasserre; Brian Finan; Daniela Cota; Carmelo Quarta
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Obesity Studies April 10 2025
BAP1 suppresses white adipose tissue browning and thermogenesis through deubiquitinating KDM1B
Pengchao Wang; Jingbo Zhu; Liuye Yang; Yilong Wang; Minglu Liang; Fengcen Li; Ze Wang; Kaiyuan Liu; Mingfa Ai; Dazhu Li; Kai Huang; Meng Du
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Pharmacology and Therapeutics April 9 2025
Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant
Silvia Torchio; Gabriel Siracusano; Federica Cuozzo; Valentina Zamarian; Silvia Pellegrini; Fabio Manenti; Riccardo Bonfanti; Giulio Frontino; Valeria Sordi; Raniero Chimienti; Lorenzo Piemonti
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Perspectives in Diabetes April 8 2025
What is Gestational Diabetes – Really?
Thomas A. Buchanan, MD; Anny H. Xiang, PhD; Kathleen A. Page, MD, MS; Richard M. Watanabe, PhD
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Islet Studies April 4 2025
Metabolic and paracrine heterogeneity of pancreatic glucagon-secreting α-cells
Haiqiang Dou; Caroline Miranda; Johan Tolö; Cristiano Santos; Rui Gao; Nikhil R. Gandasi; Thomas G. Hill; Lakshmi Kothegala; Andrei I. Tarasov; Quan Zhang; Patrik Rorsman
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Complications April 4 2025
miR-214 and its primary transcript Dnm3os regulate fibrosis and inflammation through RAGE signalling in diabetic kidney disease
Shinji Hagiwara; Jun Okabe; Mark Ziemann; Brian Drew; Maki Murakoshi; Karly C Sourris; Aaron D McClelland; Madhura Bose; Elif Ilhan Ekinci; Melinda Coughlan; Adrienne Laskowski; Hiroko Sakuma; Tomohito Gohda; Yusuke Suzuki; Mark E Cooper; Phillip Kantharidis
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Genetics/Genomes/Proteomics/Metabolomics April 4 2025
Are polymorphisms within the fructosamine-3-kinase gene associated with the discordance between HbA1c and other measures of glycaemia?
Dipuo D. Motshwari; Cindy George; Elvis N. Ngwa; Annalise E. Zemlin; Andre P. Kengne; Glenda M. Davison; Rajiv T. Erasmus; Tandi E. Matsha
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Islet Studies April 4 2025
Surface Modification of Islets with L-DOPA-KF7 Enhances Islet Survival by Inhibiting IBMIR in Intrahepatic Islet Transplantation
Daopeng Yang; Bin Qiao; Fang Bai; Jinliang Duan; Haibin Ji; Xue Ma; Zepeng Lin; Yibo Hou; Xiaoshun He; Xiaofeng Zhu; Bowen Zhuang; Xiaoyan Xie; Anbin Hu
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Pathophysiology April 2 2025
The Disposition Index in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes
Heba M Ismail; David Cuthbertson; Alfonso Galderisi; Ingrid Libman; Laura Jacobsen; Antoinette Moran; Alessandra Petrelli; Mark Atkinson; Maria J. Redondo; Tamara Hannon; Kieren J Mather; Jay M. Sosenko
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Pharmacology and Therapeutics April 2 2025
A Randomized-Controlled, Double-Masked Cross-Over Study of a GPR119 Agonist on Glucagon Counterregulation during Hypoglycemia in Type 1 Diabetes
Anika Bilal; Anna Casu; Fanchao Yi; Tumpa Dutta; Justine M. Mucinski; Gina Mercouffer; Martin C. Marak; Marcus Hompesch; David Kelley; Richard E. Pratley
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Metabolism March 28 2025
DA-1241, a GPR119 agonist, ameliorates fatty liver through the upregulation of TFEB-mediated autophagy
Jin Yoo; Ji Eun Jun; In-Kyung Jeong; Kyu Jeung Ahn; Ho Yeon Chung; Myung-Shik Lee; You-Cheol Hwang
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Obesity Studies March 11 2025
Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis
Hiro Kohda; Miyako Tanaka; Shigeyuki Shichino; Satoko Arakawa; Tadasuke Komori; Ayaka Ito; Eri Wada; Kozue Ochi; Xunmei Yuan; Takehiko Takeda; Atsuhito Saiki; Ichiro Tatsuno; Kenji Ikeda; Yuki Miyai; Atsushi Enomoto; Yoshihiro Morikawa; Shigeomi Shimizu; Satoshi Ueha; Kouji Matsushima; Yoshihiro Ogawa; Takayoshi Suganami
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Islet Studies March 10 2025
A Comparative Analysis of the Sensitivity, Specificity, Concordance, and the 5-year Predictive Power of Diabetes-related Autoantibody Assays
Jeffrey P. Krischer, PhD; Sarah Muller, BS; Lu You, PhD; Peter Achenbach, MD; Elena Bazzigaluppi, BSc; Cristina Brigatti, BSc; Vito Lampasona, MD; Anu Mathew, PhD; Peter Robinson, PhD; David Seftel, MD; George Sigal, PhD; Cheng-ting Tsai, PhD; Mingyue Wang, MD; Liping Yu, MD; Type 1 Diabetes TrialNet Study Group
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Pathophysiology January 8 2024
OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity.
Gareth S. D. Purvis; Massimo Collino; Andrea D. van Dam; Giacomo Einaudi; Yujung Ng; Mayooran Shanmuganathan; Smita Y. Patel; Christoph Thiemermann; Keith M. Channon; David R. Greaves; Oxford Acute Myocardial Infarction (OxAMI) Study
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  • Online ISSN 1939-327X
  • Print ISSN 0012-1797

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