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Journal Articles

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

Tina Fløyel, Kira Meyerovich, Michala C. Prause, Simranjeet Kaur, Caroline Frørup, Henrik B. Mortensen, Lotte B. Nielsen, Flemming Pociot, Alessandra K. Cardozo, Joachim Størling
Journal: Diabetes
Diabetes 2021;70(2):464–476
https://doi.org/10.2337/db20-0092
Published: 17 November 2020
View article titled, <em>SKAP2</em>, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
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Journal Articles

MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells

Kira Meyerovich, Natalia M. Violato, Makiko Fukaya, Violette Dirix, Nathalie Pachera, Lorella Marselli, Piero Marchetti, Andreas Strasser, Decio L. Eizirik, Alessandra K. Cardozo
Journal: Diabetes
Diabetes 2017;66(9):2446–2458
https://doi.org/10.2337/db16-1252
Published: 30 June 2017
View article titled, MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells
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Includes: Supplementary data
Journal Articles

Heterozygous Inactivation of the Na/Ca Exchanger Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass

Evrard Nguidjoe, Sophie Sokolow, Serge Bigabwa, Nathalie Pachera, Eva D'Amico, Florent Allagnat, Jean-Marie Vanderwinden, Abdullah Sener, Mario Manto, Marianne Depreter, Jan Mast, Geraldine Joanny, Eduard Montanya, Jacques Rahier, Alessandra K. Cardozo, Décio L. Eizirik, Stéphane Schurmans, André Herchuelz
Journal: Diabetes
Diabetes 2011;60(8):2076–2085
https://doi.org/10.2337/db10-0924
Published: 18 July 2011
View article titled, Heterozygous Inactivation of the Na/Ca Exchanger Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass
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Includes: Supplementary data
Journal Articles

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis

Fabrice Moore, Maikel L. Colli, Miriam Cnop, Mariana Igoillo Esteve, Alessandra K. Cardozo, Daniel A. Cunha, Marco Bugliani, Piero Marchetti, Décio L. Eizirik
Journal: Diabetes
Diabetes 2009;58(6):1283–1291
https://doi.org/10.2337/db08-1510
Published: 26 March 2009
View article titled, PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis
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Includes: Supplementary data
Journal Articles

Transcriptional Regulation of the Endoplasmic Reticulum Stress Gene Chop in Pancreatic Insulin-Producing Cells

Pierre Pirot, Fernanda Ortis, Miriam Cnop, Yanjun Ma, Linda M. Hendershot, Décio L. Eizirik, Alessandra K. Cardozo
Journal: Diabetes
Diabetes 2007;56(4):1069–1077
https://doi.org/10.2337/db06-1253
Published: 01 April 2007
View article titled, Transcriptional Regulation of the Endoplasmic Reticulum Stress Gene Chop in Pancreatic Insulin-Producing Cells
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Includes: Supplementary data
Journal Articles

Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

Alessandra K. Cardozo, Fernanda Ortis, Joachim Storling, Ying-Mei Feng, Joanne Rasschaert, Morten Tonnesen, Françoise Van Eylen, Thomas Mandrup-Poulsen, André Herchuelz, Décio L. Eizirik
Journal: Diabetes
Diabetes 2005;54(2):452–461
https://doi.org/10.2337/diabetes.54.2.452
Published: 01 February 2005
View article titled, Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca<sup>2+</sup> ATPase 2b and Deplete Endoplasmic Reticulum Ca<sup>2+</sup>, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells
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Journal Articles

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

Burak Kutlu, Alessandra K. Cardozo, Martine I. Darville, Mogens Kruhøffer, Nils Magnusson, Torben Ørntoft, Décio L. Eizirik
Journal: Diabetes
Diabetes 2003;52(11):2701–2719
https://doi.org/10.2337/diabetes.52.11.2701
Published: 01 November 2003
View article titled, Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells
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Includes: Supplementary data
Journal Articles

Molecular Regulation of Monocyte Chemoattractant Protein-1 Expression in Pancreatic β-Cells

Burak Kutlu, Martine I. Darville, Alessandra K. Cardozo, Décio L. Eizirik
Journal: Diabetes
Diabetes 2003;52(2):348–355
https://doi.org/10.2337/diabetes.52.2.348
Published: 01 February 2003
View article titled, Molecular Regulation of Monocyte Chemoattractant Protein-1 Expression in Pancreatic β-Cells
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Journal Articles

Inhibition of Cytokine-Induced NF-κB Activation by Adenovirus-Mediated Expression of a NF-κB Super-Repressor Prevents β-Cell Apoptosis

Harry Heimberg, Yves Heremans, Christian Jobin, Ruth Leemans, Alessandra K. Cardozo, Martine Darville, Décio L. Eizirik
Journal: Diabetes
Diabetes 2001;50(10):2219–2224
https://doi.org/10.2337/diabetes.50.10.2219
Published: 01 October 2001
View article titled, Inhibition of Cytokine-Induced NF-κB Activation by Adenovirus-Mediated Expression of a NF-κB Super-Repressor Prevents β-Cell Apoptosis
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Journal Articles

Identification of Novel Cytokine-Induced Genes in Pancreatic β-Cells by High-Density Oligonucleotide Arrays

Alessandra K. Cardozo, Mogens Kruhøffer, Ruth Leeman, Torben Ørntoft, Décio L. Eizirik
Journal: Diabetes
Diabetes 2001;50(5):909–920
https://doi.org/10.2337/diabetes.50.5.909
Published: 01 May 2001
View article titled, Identification of Novel Cytokine-Induced Genes in Pancreatic β-Cells by High-Density Oligonucleotide Arrays
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