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Alex Rabinovitch
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Journal Articles

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes

Song Xue, Amanda Posgai, Clive Wasserfall, Courtney Myhr, Martha Campbell-Thompson, Clayton E. Mathews, Todd Brusko, Alex Rabinovitch, Alexei Savinov, Manuela Battaglia, Desmond Schatz, Michael Haller, Mark A. Atkinson
Journal: Diabetes
Diabetes 2015;64(11):3873–3884
https://doi.org/10.2337/db15-0164
Published: 16 July 2015
View article titled, Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes
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Journal Articles

Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function

S. Alice Long, Mary Rieck, Srinath Sanda, Jennifer B. Bollyky, Peter L. Samuels, Robin Goland, Andrew Ahmann, Alex Rabinovitch, Sudeepta Aggarwal, Deborah Phippard, Laurence A. Turka, Mario R. Ehlers, Peter J. Bianchine, Karen D. Boyle, Steven A. Adah, Jeffrey A. Bluestone, Jane H. Buckner, Carla J. Greenbaum
Journal: Diabetes
Diabetes 2012;61(9):2340–2348
https://doi.org/10.2337/db12-0049
Published: 17 August 2012
View article titled, Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function
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Includes: Supplementary data
Journal Articles

Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice

Wilma L. Suarez-Pinzon, Robert F. Power, Yanhua Yan, Clive Wasserfall, Mark Atkinson, Alex Rabinovitch
Journal: Diabetes
Diabetes 2008;57(12):3281–3288
https://doi.org/10.2337/db08-0688
Published: 01 December 2008
View article titled, Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice
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Journal Articles

Combination Therapy With Epidermal Growth Factor and Gastrin Increases β-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice

Wilma L. Suarez-Pinzon, Yanhua Yan, Robert Power, Stephen J. Brand, Alex Rabinovitch
Journal: Diabetes
Diabetes 2005;54(9):2596–2601
https://doi.org/10.2337/diabetes.54.9.2596
Published: 01 September 2005
View article titled, Combination Therapy With Epidermal Growth Factor and Gastrin Increases β-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice
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Journal Articles

Poly (ADP-Ribose) Polymerase Inhibition Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice by Inducing Apoptosis of Islet-Infiltrating Leukocytes

Wilma L. Suarez-Pinzon, Jon G. Mabley, Robert Power, Csaba Szabó, Alex Rabinovitch
Journal: Diabetes
Diabetes 2003;52(7):1683–1688
https://doi.org/10.2337/diabetes.52.7.1683
Published: 01 July 2003
View article titled, Poly (ADP-Ribose) Polymerase Inhibition Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice by Inducing Apoptosis of Islet-Infiltrating Leukocytes
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Journal Articles

Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice

Alex Rabinovitch, Wilma L. Suarez-Pinzon, A.M. James Shapiro, Ray V. Rajotte, Robert Power
Journal: Diabetes
Diabetes 2002;51(3):638–645
https://doi.org/10.2337/diabetes.51.3.638
Published: 01 March 2002
View article titled, Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice
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Journal Articles

Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol

Edmond A. Ryan, Jonathan R.T. Lakey, Ray V. Rajotte, Gregory S. Korbutt, Tatsuya Kin, Sharleen Imes, Alex Rabinovitch, John F. Elliott, David Bigam, Norman M. Kneteman, Garth L. Warnock, Ingrid Larsen, A.M. James Shapiro
Journal: Diabetes
Diabetes 2001;50(4):710–719
https://doi.org/10.2337/diabetes.50.4.710
Published: 01 April 2001
View article titled, Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol
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Journal Articles

Development of Autoimmune Diabetes in NOD Mice Is Associated With the Formation of Peroxynitrite in Pancreatic Islet β-Cells

Wilma L Suarez-Pinzon, Casaba Szabó, Alex Rabinovitch
Journal: Diabetes
Diabetes 1997;46(5):907–911
https://doi.org/10.2337/diab.46.5.907
Published: 01 May 1997
View article titled, Development of Autoimmune Diabetes in NOD Mice Is Associated With the Formation of Peroxynitrite in Pancreatic Islet β-Cells
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Journal Articles

Both CD4+ and CD8+ T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction

Wilma Suarez-Pinzon, Ray V Rajotte, Tim R Mosmann, Alex Rabinovitch
Journal: Diabetes
Diabetes 1996;45(10):1350–1357
https://doi.org/10.2337/diab.45.10.1350
Published: 01 October 1996
View article titled, Both CD4<sup>+</sup> and CD8<sup>+</sup> T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction
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Journal Articles

Interferon Expression in the Pancreases of Patients With Type I Diabetes

Xiaojian Huang, Jean Yuang, Audrey Goddard, Alan Foulis, Roger F L James, Åke Lernmark, Ricardo Pujol-Borrell, Alex Rabinovitch, Nuria Somoza, Timothy A Stewart
Journal: Diabetes
Diabetes 1995;44(6):658–664
https://doi.org/10.2337/diab.44.6.658
Published: 01 June 1995
View article titled, Interferon Expression in the Pancreases of Patients With Type I Diabetes
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Journal Articles

Immunoregulatory and Cytokine Imbalances in the Pathogenesis of IDDM: Therapeutic Intervention by Immunostimulation?

Alex Rabinovitch
Journal: Diabetes
Diabetes 1994;43(5):613–621
https://doi.org/10.2337/diab.43.5.613
Published: 01 May 1994
View article titled, Immunoregulatory and Cytokine Imbalances in the Pathogenesis of IDDM: Therapeutic Intervention by Immunostimulation?
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