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Journal Articles

The Disposition Index in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes

Heba M Ismail, David Cuthbertson, Alfonso Galderisi, Ingrid Libman, Laura Jacobsen, Antoinette Moran, Alessandra Petrelli, Mark Atkinson, Maria J. Redondo, Tamara Hannon, Kieren J Mather, Jay M. Sosenko

Diabetes db241000

https://doi.org/10.2337/db24-1000

Published: 02 April 2025

View articletitled, The Disposition Index in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes

Journal Articles

Revisiting the Pattern of Loss of β-Cell Function in Preclinical Type 1 Diabetes

Mariangela Martino, Alfonso Galderisi, Carmella Evans-Molina, Colin Dayan

Diabetes 2024;73(11):1769–1779

https://doi.org/10.2337/db24-0163

Published: 06 August 2024

View articletitled, Revisiting the Pattern of Loss of β-Cell Function in Preclinical Type 1 Diabetes

Journal Articles

Alterations in Adipose Tissue Distribution, Cell Morphology, and Function Mark Primary Insulin Hypersecretion in Youth With Obesity

Domenico Tricò, Martina Chiriacò, Jessica Nouws, Alla Vash-Margita, Romy Kursawe, Elena Tarabra, Alfonso Galderisi, Andrea Natali, Cosimo Giannini, Marc Hellerstein, Ele Ferrannini, Sonia Caprio

Diabetes 2024;73(6):941–952

https://doi.org/10.2337/db23-0450

Published: 23 October 2023

View articletitled, Alterations in Adipose Tissue Distribution, Cell Morphology, and Function Mark Primary Insulin Hypersecretion in Youth With Obesity

Meeting Abstracts

342-OR: Low Incretin Effect Is Associated with Longitudinal Decline of Beta-Cell Function and Insulin Sensitivity in Obese Youth

ALFONSO GALDERISI, JESSICA O. LAT, STEPHANIE SAMUELS, BRIDGET PIERPONT, MICHELLE A. VAN NAME, NICOLA SANTORO, SONIA CAPRIO

Diabetes 2022;71(Supplement_1):342-OR

https://doi.org/10.2337/db22-342-OR

Published: 01 June 2022

View articletitled, 342-OR: Low Incretin Effect Is Associated with Longitudinal Decline of Beta-Cell Function and Insulin Sensitivity in Obese Youth

Meeting Abstracts

206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

VEDAVATI PURANDARE, ALFONSO GALDERISI, MARIANGELA MAERTINO, ANANDA BASU, CLAUDIO COBELLI, AMBIKA GOPALAKRISHNAN UNNIKRISHNAN, RITA BASU

Diabetes 2021;70(Supplement_1):206-LB

https://doi.org/10.2337/db21-206-LB

Published: 01 June 2021

View articletitled, 206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

Meeting Abstracts

67-OR: Oral Minimal Model Testing Reveals Early Impairment of Insulin Sensitivity in Type 1 Diabetes Autoantibody Positive, Nonobese, Nondysglycemic Youth

ALFONSO GALDERISI, ANTOINETTE MORAN, CARMELLA EVANS-MOLINA, MARIANGEA MARTINO, NICOLA SANTORO, SONIA CAPRIO, CLAUDIO COBELLI

Diabetes 2021;70(Supplement_1):67-OR

https://doi.org/10.2337/db21-67-OR

Published: 01 June 2021

View articletitled, 67-OR: Oral Minimal Model Testing Reveals Early Impairment of Insulin Sensitivity in Type 1 Diabetes Autoantibody Positive, Nonobese, Nondysglycemic Youth

Meeting Abstracts

978-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Adults and Adolescents without Increasing Risk of Hypoglycemia

GREGORY P. FORLENZA, BRUCE A. BUCKINGHAM, JENNIFER SHERR, R. PAUL WADWA, ALFONSO GALDERISI, LAYA EKHLASPOUR, CARI BERGET, LIANA HSU, MELINDA ZGORSKI, JOON BOK LEE, JASON B. OCONNOR, BONNIE DUMAIS, TODD VIENNEAU, LAUREN M. HUYETT, TRANG T. LY

Diabetes 2020;69(Supplement_1):978-P

https://doi.org/10.2337/db20-978-P

Published: 01 June 2020

View articletitled, 978-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Adults and Adolescents without Increasing Risk of Hypoglycemia

Meeting Abstracts

61-OR: Genetic and Metabolic Determinants of the Incretin Effect in Obese Adolescent with Prediabetes

ALFONSO GALDERISI, STEPHANIE SAMUELS, BRIDGET PIERPONT, CHIARA DALLA MAN, NICOLA SANTORO, SONIA CAPRIO

Diabetes 2020;69(Supplement_1):61-OR

https://doi.org/10.2337/db20-61-OR

Published: 01 June 2020

View articletitled, 61-OR: Genetic and Metabolic Determinants of the Incretin Effect in Obese Adolescent with Prediabetes

Meeting Abstracts

1296-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Children Aged 2-12 Years without Increasing Risk of Hypoglycemia

JENNIFER SHERR, BRUCE A. BUCKINGHAM, GREGORY P. FORLENZA, ALFONSO GALDERISI, LAYA EKHLASPOUR, R. PAUL WADWA, MELINDA ZGORSKI, RYAN S. KINGMAN, CARI BERGET, JOON BOK LEE, JASON B. OCONNOR, BONNIE DUMAIS, TODD VIENNEAU, LAUREN M. HUYETT, TRANG T. LY

Diabetes 2020;69(Supplement_1):1296-P

https://doi.org/10.2337/db20-1296-P

Published: 01 June 2020

View articletitled, 1296-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Children Aged 2-12 Years without Increasing Risk of Hypoglycemia

Journal Articles

Lower Insulin Clearance Parallels a Reduced Insulin Sensitivity in Obese Youths and Is Associated With a Decline in β-Cell Function Over Time

Alfonso Galderisi, David Polidori, Ram Weiss, Cosimo Giannini, Bridget Pierpont, Domenico Tricò, Sonia Caprio

Diabetes 2019;68(11):2074–2084

https://doi.org/10.2337/db19-0120

Published: 09 August 2019

View articletitled, Lower Insulin Clearance Parallels a Reduced Insulin Sensitivity in Obese Youths and Is Associated With a Decline in β-Cell Function Over Time

Includes: Supplementary data

Meeting Abstracts

1054-P: Insulin Sensitivity from Sensor and Pump Data in Youths with Type 1 Diabetes: Hybrid Closed-Loop Validation

MICHELE SCHIAVON, ALFONSO GALDERISI, KRISTEN A. KRAEMER, CLAUDIO COBELLI, CHIARA DALLA MAN, EDA CENGIZ

Diabetes 2019;68(Supplement_1):1054-P

https://doi.org/10.2337/db19-1054-P

Published: 01 June 2019

View articletitled, 1054-P: Insulin Sensitivity from Sensor and Pump Data in Youths with Type 1 Diabetes: Hybrid Closed-Loop Validation

Meeting Abstracts

121-OR: Insulin Clearance Is an Independent Determinant of ß-Cell Cell Function in Obese Youths

ALFONSO GALDERISI, DOMENICO TRICO, COSIMO GIANNINI, SR., NICOLA SANTORO, SONIA CAPRIO, RAM WEISS

Diabetes 2019;68(Supplement_1):121-OR

https://doi.org/10.2337/db19-121-OR

Published: 01 June 2019

View articletitled, 121-OR: Insulin Clearance Is an Independent Determinant of ß-Cell Cell Function in Obese Youths

Meeting Abstracts

1317-P: Static, but Nondynamic, ß-Cell Responsiveness to Glucose Is Affected by the Risk Variant rs7903146 of TCF7L2 and Associated with a Delayed Time-to-Glucose-Peak in Obese Youths

ALFONSO GALDERISI, DOMENICO TRICO, CHIARA DALLA MAN, STEPHAN SIEBEL, NICOLA SANTORO, BRIDGET PIERPONT, CLAUDIO COBELLI, SONIA CAPRIO

Diabetes 2019;68(Supplement_1):1317-P

https://doi.org/10.2337/db19-1317-P

Published: 01 June 2019

View articletitled, 1317-P: Static, but Nondynamic, ß-Cell Responsiveness to Glucose Is Affected by the Risk Variant rs7903146 of TCF7L2 and Associated with a Delayed Time-to-Glucose-Peak in Obese Youths

Meeting Abstracts

1318-P: Fructose Consumption Contributes to Hyperinsulinemia in Obese Adolescents through a GLP-1-Mediated Mechanism

ALFONSO GALDERISI, MICHELLE A. VAN NAME, COSIMO GIANNINI, MARY SAVOYE, SONIA CAPRIO

Diabetes 2019;68(Supplement_1):1318-P

https://doi.org/10.2337/db19-1318-P

Published: 01 June 2019

View articletitled, 1318-P: Fructose Consumption Contributes to Hyperinsulinemia in Obese Adolescents through a GLP-1-Mediated Mechanism

Meeting Abstracts

215-OR: Safety and Performance of the Omnipod Hybrid Closed-Loop System in Young Children Aged 2-6 Years with Type 1 Diabetes

BRUCE A. BUCKINGHAM, GREGORY P. FORLENZA, JENNIFER SHERR, ALFONSO GALDERISI, LAYA EKHLASPOUR, JOON BOK LEE, JASON B. OCONNOR, BONNIE DUMAIS, LAUREN M. HUYETT, JENNIFER E. LAYNE, TRANG T. LY

Diabetes 2019;68(Supplement_1):215-OR

https://doi.org/10.2337/db19-215-OR

Published: 01 June 2019

View articletitled, 215-OR: Safety and Performance of the Omnipod Hybrid Closed-Loop System in Young Children Aged 2-6 Years with Type 1 Diabetes

Meeting Abstracts

Ethnicity and Common Genetic Variants Modulate Nonalcoholic Fatty Liver Disease (NAFLD) Metabolic Phenotype in Obese Youth

DOMENICO TRICO, SONIA CAPRIO, GIUSEPPINA R. UMANO, ALFONSO GALDERISI, MARIANA M. MATA, JESSICA NOUWS, BRIDGET PIERPONT, GRACE KIM, NICOLA SANTORO

Diabetes 2018;67(Supplement_1):313-OR

https://doi.org/10.2337/db18-313-OR

Published: 01 July 2018

View articletitled, Ethnicity and Common Genetic Variants Modulate Nonalcoholic Fatty Liver Disease (NAFLD) Metabolic Phenotype in Obese Youth

Meeting Abstracts

The TCF7L2 Variant rs7903146 Affects the Risk of Youth-Onset Type 2 Diabetes by Reducing the Incretin Effect on Insulin Secretion

ALFONSO GALDERISI, BRIDGET PIERPONT, DAVID D'ALESSIO, NICOLA SANTORO, SONIA CAPRIO

Diabetes 2018;67(Supplement_1):340-OR

https://doi.org/10.2337/db18-340-OR

Published: 01 July 2018

View articletitled, The TCF7L2 Variant rs7903146 Affects the Risk of Youth-Onset Type 2 Diabetes by Reducing the Incretin Effect on Insulin Secretion

Meeting Abstracts

Suppression of Ketogenesis in Type 1 Diabetes Is Not Delayed by SGLT2 Inhibitor Therapy

STEPHAN SIEBEL, NEHA S. PATEL, ALFONSO GALDERISI, LORI R. CARRIA, WILLIAM V. TAMBORLANE, JENNIFER SHERR

Diabetes 2018;67(Supplement_1):117-LB

https://doi.org/10.2337/db18-117-LB

Published: 01 July 2018

View articletitled, Suppression of Ketogenesis in Type 1 Diabetes Is Not Delayed by SGLT2 Inhibitor Therapy

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The Disposition Index in Autoantibody-Positive Individuals at Risk for Type 1 Diabetes

Revisiting the Pattern of Loss of β-Cell Function in Preclinical Type 1 Diabetes

Alterations in Adipose Tissue Distribution, Cell Morphology, and Function Mark Primary Insulin Hypersecretion in Youth With Obesity

342-OR: Low Incretin Effect Is Associated with Longitudinal Decline of Beta-Cell Function and Insulin Sensitivity in Obese Youth

206-LB: Indian Americans as Compared with Indians Exhibit Increased Beta-Cell Responsivity and Insulin Clearance in Absence of Changes in Insulin Sensitivity

67-OR: Oral Minimal Model Testing Reveals Early Impairment of Insulin Sensitivity in Type 1 Diabetes Autoantibody Positive, Nonobese, Nondysglycemic Youth

978-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Adults and Adolescents without Increasing Risk of Hypoglycemia

61-OR: Genetic and Metabolic Determinants of the Incretin Effect in Obese Adolescent with Prediabetes

1296-P: Omnipod Personalized MPC Algorithm at Target Glucose of 110mg/dl Is Safe in Children Aged 2-12 Years without Increasing Risk of Hypoglycemia

Lower Insulin Clearance Parallels a Reduced Insulin Sensitivity in Obese Youths and Is Associated With a Decline in β-Cell Function Over Time

1054-P: Insulin Sensitivity from Sensor and Pump Data in Youths with Type 1 Diabetes: Hybrid Closed-Loop Validation

121-OR: Insulin Clearance Is an Independent Determinant of ß-Cell Cell Function in Obese Youths

1317-P: Static, but Nondynamic, ß-Cell Responsiveness to Glucose Is Affected by the Risk Variant rs7903146 of TCF7L2 and Associated with a Delayed Time-to-Glucose-Peak in Obese Youths

1318-P: Fructose Consumption Contributes to Hyperinsulinemia in Obese Adolescents through a GLP-1-Mediated Mechanism

215-OR: Safety and Performance of the Omnipod Hybrid Closed-Loop System in Young Children Aged 2-6 Years with Type 1 Diabetes

Ethnicity and Common Genetic Variants Modulate Nonalcoholic Fatty Liver Disease (NAFLD) Metabolic Phenotype in Obese Youth

The TCF7L2 Variant rs7903146 Affects the Risk of Youth-Onset Type 2 Diabetes by Reducing the Incretin Effect on Insulin Secretion

Suppression of Ketogenesis in Type 1 Diabetes Is Not Delayed by SGLT2 Inhibitor Therapy

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