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André Marette
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Meeting Abstracts

73-OR: The Plant-Based Substance Totum-63 (T63) Reduces Fasting Plasma Glucose and HbA1c in People with Prediabetes or Type 2 Diabetes (T2D)—A 24-Week Multicenter Randomized Controlled Trial (REVERSE-IT)

YOLANDA F. OTERO, PASCAL SIRVENT, ODD ERIK JOHANSEN, VIVIEN CHAVANELLE, ANNIE BOUCHARD-MERCIER, VERONIQUE SAPONE, MAXIME BARGETTO, FLORIAN LE JOUBIOUX, BRUNO PEREIRA, MURIELLE CAZAUBIEL, NATHALIE BOISSEAU, THIERRY MAUGARD, BRUNO GUIGAS, SEBASTIEN PELTIER, JEAN-MARIE BARD, HANS-JUERGEN WOERLE, SAMY HADJADJ, ANDRE MARETTE
Journal: Diabetes
Diabetes 2024;73(Supplement_1):73-OR
https://doi.org/10.2337/db24-73-OR
Published: 14 June 2024
View articletitled, 73-OR: The Plant-Based Substance Totum-63 (T63) Reduces Fasting Plasma Glucose and HbA1c in People with Prediabetes or Type 2 Diabetes (T2D)—A 24-Week Multicenter Randomized Controlled Trial (REVERSE-IT)
Meeting Abstracts

725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk

ANNIE BOUCHARD-MERCIER, YOLANDA F. OTERO, VIVIEN CHAVANELLE, JULIE MAROIS, GENEVIÈVE PILON, THIBAULT VARIN, PATRICIA L. MITCHELL, ODD ERIK JOHANSEN, MAXIME BARGETTO, VERONIQUE SAPONE, FLORIAN LE JOUBIOUX, MURIELLE CAZAUBIEL, JEAN-MARIE BARD, SEBASTIEN PELTIER, PATRICK COUTURE, MARIE-CLAUDE VOHL, PASCAL SIRVENT, ANDRE MARETTE
Journal: Diabetes
Diabetes 2024;73(Supplement_1):725-P
https://doi.org/10.2337/db24-725-P
Published: 14 June 2024
View articletitled, 725-P: TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk
Meeting Abstracts

735-P: Baseline Characteristics in the REVERSE-IT Study, a 24-Week, 600-Person Randomized Placebo-Controlled Study of the Metabolic Effects of the Combination of Five Plant Extracts TOTUM-63 (T63)

YOLANDA F. OTERO, PASCAL SIRVENT, ODD ERIK JOHANSEN, VIVIEN CHAVANELLE, MAXIME BARGETTO, VERONIQUE SAPONE, ANNIE BOUCHARD-MERCIER, FLORIAN LE JOUBIOUX, NATHALIE BOISSEAU, THIERRY MAUGARD, MURIELLE CAZAUBIEL, BRUNO PEREIRA, BRUNO GUIGAS, SAMY HADJADJ, SEBASTIEN PELTIER, ANDRE MARETTE, JEAN-MARIE BARD
Journal: Diabetes
Diabetes 2023;72(Supplement_1):735-P
https://doi.org/10.2337/db23-735-P
Published: 20 June 2023
View articletitled, 735-P: Baseline Characteristics in the REVERSE-IT Study, a 24-Week, 600-Person Randomized Placebo-Controlled Study of the Metabolic Effects of the Combination of Five Plant Extracts TOTUM-63 (T63)
Meeting Abstracts

1590-P: Post-Oral Glucose Load Hyperinsulinemia in Individuals with Metabolic Syndrome and Metabolic-Associated Fatty Liver Disease—First Steps toward the Development of Type 2 Diabetes?

GABRIELLE TRÉPANIER, THEO GIGNAC, MARION PRADEAU, ARIANNE MORISSETTE, ANNE-LAURE AGRINIER, CLAUDIA GAGNON, MARIE-CLAUDE VOHL, ANDRE MARETTE, ANNE-MARIE CARREAU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1590-P
https://doi.org/10.2337/db23-1590-P
Published: 20 June 2023
View articletitled, 1590-P: Post-Oral Glucose Load Hyperinsulinemia in Individuals with Metabolic Syndrome and Metabolic-Associated Fatty Liver Disease—First Steps toward the Development of Type 2 Diabetes?
Meeting Abstracts

1586-P: Post-OGTT Low Blood Glucose in Individuals with Metabolic Syndrome, Metabolic Phenotypes, and Metabolic-Associated Fatty Liver Disease

THEO GIGNAC, ARIANNE MORISSETTE, ANNE-LAURE AGRINIER, CLAUDIA GAGNON, MARIE-CLAUDE VOHL, ANDRE MARETTE, ANNE-MARIE CARREAU
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1586-P
https://doi.org/10.2337/db23-1586-P
Published: 20 June 2023
View articletitled, 1586-P: Post-OGTT Low Blood Glucose in Individuals with Metabolic Syndrome, Metabolic Phenotypes, and Metabolic-Associated Fatty Liver Disease
Meeting Abstracts

1561-P: Dietary Proteins Impact Glucose Tolerance and Hepatic Insulin Resistance in Mice through Modulation of the Urea Cycle

FRÉDÉRIC BÉGIN, ALEXANDRE CARON, ANDRE MARETTE
Journal: Diabetes
Diabetes 2023;72(Supplement_1):1561-P
https://doi.org/10.2337/db23-1561-P
Published: 20 June 2023
View articletitled, 1561-P: Dietary Proteins Impact Glucose Tolerance and Hepatic Insulin Resistance in Mice through Modulation of the Urea Cycle
Meeting Abstracts

1880-P: The Protein-Tyrosine Phosphatase Shp1 Interacts with PPAR Gamma and Regulates Its Transcriptional Activity through Dephosphorylation of Selected Tyrosine Sites

AMIT KUMAR, MARIE-HELENE LAVALLEE-BOURGET, MARIE-PIER FOREST, MICHAEL SCHWAB, KERSTIN BELLMANN, VANESSA HOUDE, HALIM MAAROUFI, NICOLE BEAUCHEMIN, ANDRE MARETTE
Journal: Diabetes
Diabetes 2019;68(Supplement_1):1880-P
https://doi.org/10.2337/db19-1880-P
Published: 01 June 2019
View articletitled, 1880-P: The Protein-Tyrosine Phosphatase Shp1 Interacts with PPAR Gamma and Regulates Its Transcriptional Activity through Dephosphorylation of Selected Tyrosine Sites
Meeting Abstracts

2017-P: Gut Microbes after Bariatric Surgery in Humans Improve Glucose Control in Mice without Fat Loss

FERNANDO FORATO ANHÊ, KEVIN P. FOLEY, NICOLE G. BARRA, BRITTANY M. DUGGAN, JOSEPH F. CAVALLARI, BRANDYN D. HENRIKSBO, PATRICE D. CANI, LAURENT BIERTHO, ANDRE TCHERNOF, ANDRE MARETTE, JONATHAN D. SCHERTZER
Journal: Diabetes
Diabetes 2019;68(Supplement_1):2017-P
https://doi.org/10.2337/db19-2017-P
Published: 01 June 2019
View articletitled, 2017-P: Gut Microbes after Bariatric Surgery in Humans Improve Glucose Control in Mice without Fat Loss
Journal Articles

Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure

Sophie Carter, Stéphanie Miard, Alexandre Caron, Sandrine Sallé-Lefort, Philippe St-Pierre, Fernando Forato Anhê, Emilie Lavoie-Charland, Pascale Blais-Lecours, Marie-Claude Drolet, Julie S. Lefebvre, Julie Lacombe, Yves Deshaies, Jacques Couet, Mathieu Laplante, Mathieu Ferron, Yohan Bossé, André Marette, Denis Richard, David Marsolais, Frédéric Picard
Journal: Diabetes
Diabetes 2018;67(7):1285–1296
https://doi.org/10.2337/db17-0558
Published: 01 March 2018
View articletitled, Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure
Open the PDF for Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure in another window
Includes: Supplementary data
Journal Articles

Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease

Milene Vandal, Phillip J. White, Cyntia Tremblay, Isabelle St-Amour, Geneviève Chevrier, Vincent Emond, Dominique Lefrançois, Jessica Virgili, Emmanuel Planel, Yves Giguere, Andre Marette, Frederic Calon
Journal: Diabetes
Diabetes 2014;63(12):4291–4301
https://doi.org/10.2337/db14-0375
Published: 13 November 2014
View articletitled, Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease
Open the PDF for Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease in another window
Includes: Supplementary data
Journal Articles

Statin-Induced Insulin Resistance Through Inflammasome Activation: Sailing Between Scylla and Charybdis

Patricia Mitchell, André Marette
Journal: Diabetes
Diabetes 2014;63(11):3569–3571
https://doi.org/10.2337/db14-1059
Published: 13 October 2014
View articletitled, Statin-Induced Insulin Resistance Through Inflammasome Activation: Sailing Between Scylla and Charybdis
Open the PDF for Statin-Induced Insulin Resistance Through Inflammasome Activation: Sailing Between Scylla and Charybdis in another window
Journal Articles

Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance

Elaine Xu, Alexandre Charbonneau, Yannève Rolland, Kerstin Bellmann, Lily Pao, Katherine A. Siminovitch, Benjamin G. Neel, Nicole Beauchemin, André Marette
Journal: Diabetes
Diabetes 2012;61(8):1949–1958
https://doi.org/10.2337/db11-1502
Published: 17 July 2012
View articletitled, Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance
Open the PDF for Hepatocyte-Specific Ptpn6 Deletion Protects From Obesity-Linked Hepatic Insulin Resistance in another window
Includes: Supplementary data
Journal Articles

Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance

Erin E. Mulvihill, Julia M. Assini, Justin K. Lee, Emma M. Allister, Brian G. Sutherland, Julie B. Koppes, Cynthia G. Sawyez, Jane Y. Edwards, Dawn E. Telford, Alexandre Charbonneau, Philippe St-Pierre, André Marette, Murray W. Huff
Journal: Diabetes
Diabetes 2011;60(5):1446–1457
https://doi.org/10.2337/db10-0589
Published: 23 April 2011
View articletitled, Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance
Open the PDF for Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance in another window
Includes: Supplementary data
Journal Articles

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice

Phillip J. White, Makoto Arita, Ryo Taguchi, Jing X. Kang, André Marette
Journal: Diabetes
Diabetes 2010;59(12):3066–3073
https://doi.org/10.2337/db10-0054
Published: 14 September 2010
View articletitled, Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice
Open the PDF for Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice in another window
Journal Articles

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

Vanessa P. Houde, Sophie Brûlé, William T. Festuccia, Pierre-Gilles Blanchard, Kerstin Bellmann, Yves Deshaies, André Marette
Journal: Diabetes
Diabetes 2010;59(6):1338–1348
https://doi.org/10.2337/db09-1324
Published: 18 March 2010
View articletitled, Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
Open the PDF for Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue in another window
Includes: Supplementary data
Journal Articles

Inducible Nitric Oxide Synthase Induction Underlies Lipid-Induced Hepatic Insulin Resistance in Mice: Potential Role of Tyrosine Nitration of Insulin Signaling Proteins

Alexandre Charbonneau, André Marette
Journal: Diabetes
Diabetes 2010;59(4):861–871
https://doi.org/10.2337/db09-1238
Published: 26 January 2010
View articletitled, Inducible Nitric Oxide Synthase Induction Underlies Lipid-Induced Hepatic Insulin Resistance in Mice: Potential Role of Tyrosine Nitration of Insulin Signaling Proteins
Open the PDF for Inducible Nitric Oxide Synthase Induction Underlies Lipid-Induced Hepatic Insulin Resistance in Mice: Potential Role of Tyrosine Nitration of Insulin Signaling Proteins in another window
Includes: Supplementary data
Journal Articles

Selective Impairment in GLUT4 Translocation to Transverse Tubules in Skeletal Muscle of Streptozotocin-Induced Diabetic Rats

Luce Dombrowski, Denis Roy, André Marette
Journal: Diabetes
Diabetes 1998;47(1):5–12
https://doi.org/10.2337/diab.47.1.5
Published: 01 January 1998
View articletitled, Selective Impairment in GLUT4 Translocation to Transverse Tubules in Skeletal Muscle of Streptozotocin-Induced Diabetic Rats
Open the PDF for Selective Impairment in GLUT4 Translocation to Transverse Tubules in Skeletal Muscle of Streptozotocin-Induced Diabetic Rats in another window
Journal Articles

Expression of Nitric Oxide Synthase in Skeletal Muscle: A Novel Role for Nitric Oxide as a Modulator of Insulin Action

Sonia Kapur, Sylvain Bédard, Bruno Marcotte, Claude H Côté, André Marette
Journal: Diabetes
Diabetes 1997;46(11):1691–1700
https://doi.org/10.2337/diab.46.11.1691
Published: 01 November 1997
View articletitled, Expression of Nitric Oxide Synthase in Skeletal Muscle: A Novel Role for Nitric Oxide as a Modulator of Insulin Action
Open the PDF for Expression of Nitric Oxide Synthase in Skeletal Muscle: A Novel Role for Nitric Oxide as a Modulator of Insulin Action in another window
Journal Articles

Differential Regulation of GLUT1 and GLUT4 Glucose Transporters in Skeletal Muscle of a New Model of Type II Diabetes: The Obese SHR/N-cp Rat

André Marette, Claude Atgié, Zhi Liu, Ludwik J Bukowiecki, Aamira Klip
Journal: Diabetes
Diabetes 1993;42(8):1195–1201
https://doi.org/10.2337/diab.42.8.1195
Published: 01 August 1993
View articletitled, Differential Regulation of GLUT1 and GLUT4 Glucose Transporters in Skeletal Muscle of a New Model of Type II Diabetes: The Obese SHR/N-cp Rat
Open the PDF for Differential Regulation of GLUT1 and GLUT4 Glucose Transporters in Skeletal Muscle of a New Model of Type II Diabetes: The Obese SHR/N-cp Rat in another window
Journal Articles

Opposite Effects of Hyperglycemia and Insulin Deficiency on Liver Glycogen Synthase Phosphatase Activity in the Diabetic Rat

Louis Lavoie, Dimitrios Dimitrakoudis, Andre Marette, Borhane Annabi, Amira Klip, Mladen Vranic, Gerald Van De Werve
Journal: Diabetes
Diabetes 1993;42(2):363–366
https://doi.org/10.2337/diab.42.2.363
Published: 01 February 1993
View articletitled, Opposite Effects of Hyperglycemia and Insulin Deficiency on Liver Glycogen Synthase Phosphatase Activity in the Diabetic Rat
Open the PDF for Opposite Effects of Hyperglycemia and Insulin Deficiency on Liver Glycogen Synthase Phosphatase Activity in the Diabetic Rat in another window