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Journal Articles

Brown Adipose Tissue Volume and Fat Content Are Positively Associated With Whole-Body Adiposity in Young Men—Not in Women

Guillermo Sanchez-Delgado, Borja Martinez-Tellez, Francisco M. Acosta, Samuel Virtue, Antonio Vidal-Puig, Angel Gil, Jose M. Llamas-Elvira, Jonatan R. Ruiz

Diabetes 2021;70(7):1473–1485

https://doi.org/10.2337/db21-0011

Published: 15 April 2021

View article titled, Brown Adipose Tissue Volume and Fat Content Are Positively Associated With Whole-Body Adiposity in Young Men—Not in Women

Journal Articles

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

Vanessa Pellegrinelli, Christine Rouault, Sergio Rodriguez-Cuenca, Victorine Albert, Frédérique Edom-Vovard, Antonio Vidal-Puig, Karine Clément, Gillian S. Butler-Browne, Danièle Lacasa

Diabetes 2015;64(9):3121–3134

https://doi.org/10.2337/db14-0796

Published: 18 February 2015

View article titled, Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

Includes: Supplementary data

Journal Articles

Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of degs1 Impairs Adipocyte Differentiation and Function

Nuria Barbarroja, Sergio Rodriguez-Cuenca, Heli Nygren, Antonio Camargo, Ana Pirraco, Joana Relat, Irene Cuadrado, Vanessa Pellegrinelli, Gema Medina-Gomez, Chary Lopez-Pedrera, Francisco J. Tinahones, J. David Symons, Scott A. Summers, Matej Oresic, Antonio Vidal-Puig

Diabetes 2015;64(4):1180–1192

https://doi.org/10.2337/db14-0359

Published: 28 October 2014

View article titled, Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of <em>degs1</em> Impairs Adipocyte Differentiation and Function

Includes: Supplementary data

Journal Articles

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

Diabetes 2013;62(11):3697–3708

https://doi.org/10.2337/db12-1748

Published: 18 October 2013

View article titled, Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

Includes: Supplementary data

Journal Articles

A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization

Sam Virtue, Helena Feldmann, Mark Christian, Chong Yew Tan, Mojgan Masoodi, Martin Dale, Chris Lelliott, Keith Burling, Mark Campbell, Naomi Eguchi, Peter Voshol, Jaswinder K. Sethi, Malcolm Parker, Yoshihiro Urade, Julian L. Griffin, Barbara Cannon, Antonio Vidal-Puig

Diabetes 2012;61(12):3139–3147

https://doi.org/10.2337/db12-0015

Published: 15 November 2012

View article titled, A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization

Includes: Supplementary data

Journal Articles

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

Pablo B. Martínez de Morentin, Andrew J. Whittle, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, Antonio Vidal-Puig, Miguel López

Diabetes 2012;61(4):807–817

https://doi.org/10.2337/db11-1079

Published: 14 March 2012

View article titled, Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

Includes: Supplementary data

Journal Articles

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Diabetes 2012;61(4):915–924

https://doi.org/10.2337/db11-0963

Published: 14 March 2012

View article titled, Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Journal Articles

Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

Xavier Prieur, Crystal Y.L. Mok, Vidya R. Velagapudi, Vanessa Núñez, Lucía Fuentes, David Montaner, Ko Ishikawa, Alberto Camacho, Nuria Barbarroja, Stephen O’Rahilly, Jaswinder K. Sethi, Joaquin Dopazo, Matej Orešič, Mercedes Ricote, Antonio Vidal-Puig

Diabetes 2011;60(3):797–809

https://doi.org/10.2337/db10-0705

Published: 21 February 2011

View article titled, Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

Includes: Supplementary data

Journal Articles

Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance

Jose Manuel Fernandez-Real, Javier A. Menendez, Jose Maria Moreno-Navarrete, Matthias Blüher, Alejandro Vazquez-Martin, María Jesús Vázquez, Francisco Ortega, Carlos Diéguez, Gema Frühbeck, Wifredo Ricart, Antonio Vidal-Puig

Diabetes 2010;59(6):1506–1511

https://doi.org/10.2337/db09-1756

Published: 18 March 2010

View article titled, Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance

Includes: Supplementary data

Journal Articles

IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance

Stephen B. Wheatcroft, Mark T. Kearney, Ajay M. Shah, Vivienne A. Ezzat, John R. Miell, Michael Modo, Stephen C.R. Williams, Will P. Cawthorn, Gema Medina-Gomez, Antonio Vidal-Puig, Jaswinder K. Sethi, Paul A. Crossey

Diabetes 2007;56(2):285–294

https://doi.org/10.2337/db06-0436

Published: 01 February 2007

View article titled, IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance

Journal Articles

Leptin Deficiency Unmasks the Deleterious Effects of Impaired Peroxisome Proliferator–Activated Receptor γ Function (P465L PPARγ) in Mice

Sarah L. Gray, Edoardo Dalla Nora, Johannes Grosse, Monia Manieri, Tobias Stoeger, Gema Medina-Gomez, Keith Burling, Sigrid Wattler, Andreas Russ, Giles S.H. Yeo, V. Krishna Chatterjee, Stephen O’Rahilly, Peter J. Voshol, Saverio Cinti, Antonio Vidal-Puig

Diabetes 2006;55(10):2669–2677

https://doi.org/10.2337/db06-0389

Published: 01 October 2006

View article titled, Leptin Deficiency Unmasks the Deleterious Effects of Impaired Peroxisome Proliferator–Activated Receptor γ Function (P465L PPARγ) in Mice

Includes: Supplementary data

Journal Articles

The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Diabetes 2005;54(6):1706–1716

https://doi.org/10.2337/diabetes.54.6.1706

Published: 01 June 2005

View article titled, The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Includes: Supplementary data

Journal Articles

Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes

Matthias Laudes, Inês Barroso, Jian’an Luan, Maria A. Soos, Giles Yeo, Aline Meirhaeghe, Lisa Logie, Antonio Vidal-Puig, Alan J. Schafer, Nick J. Wareham, Stephen O’Rahilly

Diabetes 2004;53(3):842–846

https://doi.org/10.2337/diabetes.53.3.842

Published: 01 March 2004

View article titled, Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes

Journal Articles

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

David B. Savage, Garry D. Tan, Carlo L. Acerini, Susan A. Jebb, Maura Agostini, Mark Gurnell, Rachel L. Williams, A. Margot Umpleby, E. Louise Thomas, Jimmy D. Bell, Adrian K. Dixon, Fidelma Dunne, Romina Boiani, Saverio Cinti, Antonio Vidal-Puig, Fredrik Karpe, V. Krishna K. Chatterjee, Stephen O’Rahilly

Diabetes 2003;52(4):910–917

https://doi.org/10.2337/diabetes.52.4.910

Published: 01 April 2003

View article titled, Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

Journal Articles

Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists

Ciaran P. Sewter, Fiona Blows, Antonio Vidal-Puig, Stephen O’Rahilly

Diabetes 2002;51(3):718–723

https://doi.org/10.2337/diabetes.51.3.718

Published: 01 March 2002

View article titled, Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists

Journal Articles

Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans

David B. Savage, Ciaran P. Sewter, Ellen S. Klenk, David G. Segal, Antonio Vidal-Puig, Robert V. Considine, Stephen O’Rahilly

Diabetes 2001;50(10):2199–2202

https://doi.org/10.2337/diabetes.50.10.2199

Published: 01 October 2001

View article titled, Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans

Journal Articles

Analysis of the Hexokinase II Gene in Subjects With Insulin Resistance and NIDDM and Detection of a Gln¹⁴²→His Substitution

Antonio Vidal-Puig, Richard L Printz, Irene M Stratton, Daryl K Granner, David E Moller

Diabetes 1995;44(3):340–346

https://doi.org/10.2337/diab.44.3.340

Published: 01 March 1995

View article titled, Analysis of the Hexokinase II Gene in Subjects With Insulin Resistance and NIDDM and Detection of a Gln<sup>142</sup>→His Substitution

NARROW

Brown Adipose Tissue Volume and Fat Content Are Positively Associated With Whole-Body Adiposity in Young Men—Not in Women

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of degs1 Impairs Adipocyte Differentiation and Function

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

A New Role for Lipocalin Prostaglandin D Synthase in the Regulation of Brown Adipose Tissue Substrate Utilization

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance

IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance

Leptin Deficiency Unmasks the Deleterious Effects of Impaired Peroxisome Proliferator–Activated Receptor γ Function (P465L PPARγ) in Mice

The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Genetic Variants in Human Sterol Regulatory Element Binding Protein-1c in Syndromes of Severe Insulin Resistance and Type 2 Diabetes

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-γ

Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists

Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans

Analysis of the Hexokinase II Gene in Subjects With Insulin Resistance and NIDDM and Detection of a Gln¹⁴²→His Substitution

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