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Meeting Abstracts

1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications

CHUN KWAN O, BAOQI FAN, SANDRA T.F. TSOI, CLAUDIA H. TAM, RAYMOND WAN, ERIC S.H. LAU, MAI SHI, CADMON K.P. LIM, ELAINE CHOW, ALICE P. KONG, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN

Diabetes 2024;73(Supplement_1):1477-P

https://doi.org/10.2337/db24-1477-P

Published: 14 June 2024

View article titled, 1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications

Journal Articles

Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes

Yingnan Fan, Elaine Chow, Cadmon K.P. Lim, Yong Hou, Sandra T.F. Tsoi, Baoqi Fan, Eric S.H. Lau, Alice P.S. Kong, Ronald C.W. Ma, Hongjiang Wu, Juliana C.N. Chan, Andrea O.Y. Luk

Diabetes 2024;73(6):953–963

https://doi.org/10.2337/db23-0966

Published: 20 March 2024

View article titled, Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes

Meeting Abstracts

1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile

ANDREA LUK, YINGNAN FAN, BAOQI FAN, CADMON K.P. LIM, ERIC S.H. LAU, EMILY W.M. POON, SANDRA T.F. TSOI, RISA OZAKI, RONALD C. MA, ELAINE CHOW, ALICE P. KONG, JULIANA C. CHAN

Diabetes 2023;72(Supplement_1):1829-PUB

https://doi.org/10.2337/db23-1829-PUB

Published: 23 June 2023

View article titled, 1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile

Meeting Abstracts

126-OR: Metformin Discontinuation and Clinical Outcomes in Patients with Diabetes and Advanced Chronic Kidney Disease—A Prospective Cohort Study

AIMIN YANG, MAI SHI, HONGJIANG WU, ERIC S.H. LAU, JOHNNY T.K. CHEUNG, XINGE ZHANG, BAOQI FAN, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW

Diabetes 2023;72(Supplement_1):126-OR

https://doi.org/10.2337/db23-126-OR

Published: 20 June 2023

View article titled, 126-OR: Metformin Discontinuation and Clinical Outcomes in Patients with Diabetes and Advanced Chronic Kidney Disease—A Prospective Cohort Study

Meeting Abstracts

1414-P: Stalling of Trends in Glycemic and Risk Factors Control in People with Type 2 Diabetes in Hong Kong in 2000–2019

HONGJIANG WU, ERIC S.H. LAU, AIMIN YANG, XINGE ZHANG, BAOQI FAN, RONALD C. MA, ALICE P. KONG, ELAINE CHOW, JULIANA C. CHAN, ANDREA LUK

Diabetes 2023;72(Supplement_1):1414-P

https://doi.org/10.2337/db23-1414-P

Published: 20 June 2023

View article titled, 1414-P: Stalling of Trends in Glycemic and Risk Factors Control in People with Type 2 Diabetes in Hong Kong in 2000–2019

Meeting Abstracts

1473-P: A Data-Driven Cluster Analysis of Renal Complications in Patients with Type 2 Diabetes—From Phenotypic Observation to Genetic Discovery

MAI SHI, CLAUDIA H. TAM, ERIC S.H. LAU, AIMIN YANG, HONGJIANG WU, BAOQI FAN, ALICE P. KONG, ANDREA LUK, ELAINE CHOW, JULIANA C. CHAN, RONALD C. MA

Diabetes 2023;72(Supplement_1):1473-P

https://doi.org/10.2337/db23-1473-P

Published: 20 June 2023

View article titled, 1473-P: A Data-Driven Cluster Analysis of Renal Complications in Patients with Type 2 Diabetes—From Phenotypic Observation to Genetic Discovery

Meeting Abstracts

1472-P: Polygenic Risk Score for Liver Fat Predicts Earlier Onset of Type 2 Diabetes in an East Asian Population

GECHANG YU, RONALD C. MA, CLAUDIA H. TAM, MAI SHI, BAOQI FAN, CADMON K. LIM, JULIANA C. CHAN, MICHAEL N. WEEDON, RICHARD A. ORAM, CHUIGUO HUANG, ANDREA LUK, ERIC S.H. LAU

Diabetes 2023;72(Supplement_1):1472-P

https://doi.org/10.2337/db23-1472-P

Published: 20 June 2023

View article titled, 1472-P: Polygenic Risk Score for Liver Fat Predicts Earlier Onset of Type 2 Diabetes in an East Asian Population

Journal Articles

Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes

Elaine Chow, Ke Wang, Cadmon K.P. Lim, Sandra T.F. Tsoi, Baoqi Fan, Emily Poon, Andrea O.Y. Luk, Ronald C.W. Ma, Ele Ferrannini, Andrea Mari, Li Chen, Juliana C.N. Chan

Diabetes 2023;72(2):299–308

https://doi.org/10.2337/db22-0708

Published: 28 October 2022

View article titled, Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes

Meeting Abstracts

18-OR: Discontinuation of Renin Angiotensin System Inhibitor and Cardiovascular-Renal Events in Advanced Diabetic Kidney Disease

MAI SHI, AIMIN YANG, ERIC S.H. LAU, HONGJIANG WU, XINGE ZHANG, BAOQI FAN, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW

Diabetes 2022;71(Supplement_1):18-OR

https://doi.org/10.2337/db22-18-OR

Published: 01 June 2022

View article titled, 18-OR: Discontinuation of Renin Angiotensin System Inhibitor and Cardiovascular-Renal Events in Advanced Diabetic Kidney Disease

Meeting Abstracts

1274-P: Prevalence and Clinical Characteristics of Monogenic Diabetes in Chinese Population

SANDRA TSOI, CADMON K. LIM, RONALD C. MA, ERIC S. LAU, BAOQI FAN, ELAINE CHOW, ALICE P. KONG, JULIANA C. CHAN, ANDREA LUK

Diabetes 2022;71(Supplement_1):1274-P

https://doi.org/10.2337/db22-1274-P

Published: 01 June 2022

View article titled, 1274-P: Prevalence and Clinical Characteristics of Monogenic Diabetes in Chinese Population

Meeting Abstracts

261-OR: Dorzagliatin, a Dual-Acting Glucokinase Activator. Improves Insulin Secretion and Glucose Sensitivity in Glucokinase-Maturity-Onset Diabetes of the Young (GCK-MODY)

ELAINE CHOW, KE WANG, CADMON K.P. LIM, SANDRA TSOI, BAOQI FAN, ANDREA LUK, RONALD C. MA, ELE FERRANNINI, ANDREA MARI, LI CHEN, JULIANA C. CHAN

Diabetes 2022;71(Supplement_1):261-OR

https://doi.org/10.2337/db22-261-OR

Published: 01 June 2022

View article titled, 261-OR: Dorzagliatin, a Dual-Acting Glucokinase Activator. Improves Insulin Secretion and Glucose Sensitivity in Glucokinase-Maturity-Onset Diabetes of the Young (GCK-MODY)

Meeting Abstracts

1186-P: The Effect of Age on the Risk Relationship between Prediabetes and Mortality and Major Adverse Clinical Events

XINGE ZHANG, HONGJIANG WU, ERIC S.H. LAU, MAI SHI, BAOQI FAN, AIMIN YANG, ELAINE CHOW, ALICE P. KONG, JULIANA C. CHAN, RONALD C. MA, ANDREA LUK

Diabetes 2022;71(Supplement_1):1186-P

https://doi.org/10.2337/db22-1186-P

Published: 01 June 2022

View article titled, 1186-P: The Effect of Age on the Risk Relationship between Prediabetes and Mortality and Major Adverse Clinical Events

Meeting Abstracts

1159-P: Associations of HOMA2 with Clinical Outcomes in Type 2 Diabetes

BAOQI FAN, ERIC S.H. LAU, HONGJIANG WU, MAI SHI, AIMIN YANG, CADMON K. LIM, ALICE P. KONG, ELAINE CHOW, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN

Diabetes 2022;71(Supplement_1):1159-P

https://doi.org/10.2337/db22-1159-P

Published: 01 June 2022

View article titled, 1159-P: Associations of HOMA2 with Clinical Outcomes in Type 2 Diabetes

Meeting Abstracts

1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

BAOQI FAN, ERIC S.H. LAU, HONGJIANG WU, MAI SHI, AIMIN YANG, CADMON K.P. LIM, ALICE P. KONG, ELAINE CHOW, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN

Diabetes 2022;71(Supplement_1):1211-P

https://doi.org/10.2337/db22-1211-P

Published: 01 June 2022

View article titled, 1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

Meeting Abstracts

1208-P: Age-Specific Association between Risk Factors and All-Cause and Cause-Specific Mortality in People with Type 2 Diabetes

HONGJIANG WU, ERIC S.H. LAU, AIMIN YANG, XINGE ZHANG, BAOQI FAN, RONALD C. MA, ALICE P. KONG, ELAINE CHOW, JULIANA C. CHAN, ANDREA LUK

Diabetes 2022;71(Supplement_1):1208-P

https://doi.org/10.2337/db22-1208-P

Published: 01 June 2022

View article titled, 1208-P: Age-Specific Association between Risk Factors and All-Cause and Cause-Specific Mortality in People with Type 2 Diabetes

Meeting Abstracts

934-P: Real-World Evidence of Glucose Lowering Drug Use, Glycemic Outcomes, and Severe Hypoglycemia in Hong Kong: Eighteen-Year Trends in 0.9 Million Adults with Diabetes

AIMIN YANG, HONGJIANG WU, ERIC S.H. LAU, XINGE ZHANG, SR., MAI SHI, BAOQI FAN, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW

Diabetes 2022;71(Supplement_1):934-P

https://doi.org/10.2337/db22-934-P

Published: 01 June 2022

View article titled, 934-P: Real-World Evidence of Glucose Lowering Drug Use, Glycemic Outcomes, and Severe Hypoglycemia in Hong Kong: Eighteen-Year Trends in 0.9 Million Adults with Diabetes

Journal Articles

Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

Diabetes 2022;71(3):520–529

https://doi.org/10.2337/db21-0694

Published: 18 January 2022

View article titled, Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

Meeting Abstracts

1071-P: Long-Term Renin-Angiotensin System Inhibitor Use and Risk of Pneumonia and Pneumonia-Related Death in Type 2 Diabetes

MAI SHI, AIMIN YANG, ERIC S.H. LAU, HONGJIANG WU, BAOQI FAN, ALICE P. KONG, ANDREA LUK, RONALD C. MA, JULIANA C. CHAN, ELAINE CHOW

Diabetes 2021;70(Supplement_1):1071-P

https://doi.org/10.2337/db21-1071-P

Published: 01 June 2021

View article titled, 1071-P: Long-Term Renin-Angiotensin System Inhibitor Use and Risk of Pneumonia and Pneumonia-Related Death in Type 2 Diabetes

Meeting Abstracts

1001-P: HOMA2 IR and HOMA2 Beta on Onset and Progression of Diabetes in Young to Middle-Aged Subjects

BAOQI FAN, HONGJIANG WU, MAI SHI, AIMIN YANG, CLAUDIA H. TAM, ERIC S.H. LAU, DANDAN MAO, CADMON K.P. LIM, ALICE P. KONG, ELAINE CHOW, RONALD C. MA, ANDREA LUK, JULIANA C. CHAN

Diabetes 2021;70(Supplement_1):1001-P

https://doi.org/10.2337/db21-1001-P

Published: 01 June 2021

View article titled, 1001-P: HOMA2 IR and HOMA2 Beta on Onset and Progression of Diabetes in Young to Middle-Aged Subjects

Meeting Abstracts

1133-P: Monogenic Diabetes in Chinese with Young-Onset Diabetes

SANDRA TSOI, CADMON K.P. LIM, RONALD C. MA, ERIC S.H. LAU, BAOQI FAN, ELAINE CHOW, ALICE P. KONG, JULIANA C. CHAN, ANDREA LUK

Diabetes 2021;70(Supplement_1):1133-P

https://doi.org/10.2337/db21-1133-P

Published: 01 June 2021

View article titled, 1133-P: Monogenic Diabetes in Chinese with Young-Onset Diabetes

NARROW

1477-P: Polygenic Risk Score (PRS) Derived from Common Variants of Monogenic Diabetes Genes (MDG) Predicts Young Onset Diabetes (YOD) and Cardiovascular(CV)-Kidney Complications

Comparison of β-Cell Function and Insulin Sensitivity Between Normal-Weight and Obese Chinese With Young-Onset Type 2 Diabetes

1829-PUB: Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes Randomised Controlled Trial (PRISM-RCT) in Chinese Patients with Young-Onset Diabetes—Study Design and Baseline Profile

126-OR: Metformin Discontinuation and Clinical Outcomes in Patients with Diabetes and Advanced Chronic Kidney Disease—A Prospective Cohort Study

1414-P: Stalling of Trends in Glycemic and Risk Factors Control in People with Type 2 Diabetes in Hong Kong in 2000–2019

1473-P: A Data-Driven Cluster Analysis of Renal Complications in Patients with Type 2 Diabetes—From Phenotypic Observation to Genetic Discovery

1472-P: Polygenic Risk Score for Liver Fat Predicts Earlier Onset of Type 2 Diabetes in an East Asian Population

Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase Maturity-Onset Diabetes of the Young and Recent-Onset Type 2 Diabetes

18-OR: Discontinuation of Renin Angiotensin System Inhibitor and Cardiovascular-Renal Events in Advanced Diabetic Kidney Disease

1274-P: Prevalence and Clinical Characteristics of Monogenic Diabetes in Chinese Population

261-OR: Dorzagliatin, a Dual-Acting Glucokinase Activator. Improves Insulin Secretion and Glucose Sensitivity in Glucokinase-Maturity-Onset Diabetes of the Young (GCK-MODY)

1186-P: The Effect of Age on the Risk Relationship between Prediabetes and Mortality and Major Adverse Clinical Events

1159-P: Associations of HOMA2 with Clinical Outcomes in Type 2 Diabetes

1211-P: Associations of C-peptide, HOMA2, and GADA with Insulin Initiation and Risk of Hypoglycemia in Type 2 Diabetes

1208-P: Age-Specific Association between Risk Factors and All-Cause and Cause-Specific Mortality in People with Type 2 Diabetes

934-P: Real-World Evidence of Glucose Lowering Drug Use, Glycemic Outcomes, and Severe Hypoglycemia in Hong Kong: Eighteen-Year Trends in 0.9 Million Adults with Diabetes

Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

1071-P: Long-Term Renin-Angiotensin System Inhibitor Use and Risk of Pneumonia and Pneumonia-Related Death in Type 2 Diabetes

1001-P: HOMA2 IR and HOMA2 Beta on Onset and Progression of Diabetes in Young to Middle-Aged Subjects

1133-P: Monogenic Diabetes in Chinese with Young-Onset Diabetes

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