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Bernard Portha
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Journal Articles

Degradation of cAMP-Responsive Element–Binding Protein by the Ubiquitin-Proteasome Pathway Contributes to Glucotoxicity in β-Cells and Human Pancreatic Islets

Safia Costes, Brigitte Vandewalle, Cécile Tourrel-Cuzin, Christophe Broca, Nathalie Linck, Gyslaine Bertrand, Julie Kerr-Conte, Bernard Portha, François Pattou, Joel Bockaert, Stéphane Dalle
Journal: Diabetes
Diabetes 2009;58(5):1105–1115
https://doi.org/10.2337/db08-0926
Published: 17 February 2009
View article titled, Degradation of cAMP-Responsive Element–Binding Protein by the Ubiquitin-Proteasome Pathway Contributes to Glucotoxicity in β-Cells and Human Pancreatic Islets
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Journal Articles

Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat

Françoise Homo-Delarche, Sophie Calderari, Jean-Claude Irminger, Marie-Noëlle Gangnerau, Josiane Coulaud, Katharina Rickenbach, Manuel Dolz, Philippe Halban, Bernard Portha, Patricia Serradas
Journal: Diabetes
Diabetes 2006;55(6):1625–1633
https://doi.org/10.2337/db05-1526
Published: 01 June 2006
View article titled, Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat
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Journal Articles

Restitution of Defective Glucose-Stimulated Insulin Secretion in Diabetic GK Rat by Acetylcholine Uncovers Paradoxical Stimulatory Effect of β-Cell Muscarinic Receptor Activation on cAMP Production

Manuel Dolz, Danielle Bailbé, Marie-Hélène Giroix, Sophie Calderari, Marie-Noelle Gangnerau, Patricia Serradas, Katharina Rickenbach, Jean-Claude Irminger, Bernard Portha
Journal: Diabetes
Diabetes 2005;54(11):3229–3237
https://doi.org/10.2337/diabetes.54.11.3229
Published: 01 November 2005
View article titled, Restitution of Defective Glucose-Stimulated Insulin Secretion in Diabetic GK Rat by Acetylcholine Uncovers Paradoxical Stimulatory Effect of β-Cell Muscarinic Receptor Activation on cAMP Production
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Journal Articles

Persistent Improvement of Type 2 Diabetes in the Goto-Kakizaki Rat Model by Expansion of the β-Cell Mass During the Prediabetic Period With Glucagon-Like Peptide-1 or Exendin-4

Cécile Tourrel, Danielle Bailbe, Matthieu Lacorne, Marie-Jo Meile, Micheline Kergoat, Bernard Portha
Journal: Diabetes
Diabetes 2002;51(5):1443–1452
https://doi.org/10.2337/diabetes.51.5.1443
Published: 01 May 2002
View article titled, Persistent Improvement of Type 2 Diabetes in the Goto-Kakizaki Rat Model by Expansion of the β-Cell Mass During the Prediabetic Period With Glucagon-Like Peptide-1 or Exendin-4
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Journal Articles

Fetal Insulin-Like Growth Factor-2 Production Is Impaired in the GK Rat Model of Type 2 Diabetes

Patricia Serradas, Luis Goya, Matthieu Lacorne, Marie-Noëlle Gangnerau, Sonia Ramos, Carmen Alvarez, Ana-Maria Pascual-Leone, Bernard Portha
Journal: Diabetes
Diabetes 2002;51(2):392–397
https://doi.org/10.2337/diabetes.51.2.392
Published: 01 February 2002
View article titled, Fetal Insulin-Like Growth Factor-2 Production Is Impaired in the GK Rat Model of Type 2 Diabetes
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Journal Articles

Glucagon-Like Peptide-1 and Exendin-4 Stimulate β-Cell Neogenesis in Streptozotocin-Treated Newborn Rats Resulting in Persistently Improved Glucose Homeostasis at Adult Age

Cécile Tourrel, Danielle Bailbé, Marie-Jo Meile, Micheline Kergoat, Bernard Portha
Journal: Diabetes
Diabetes 2001;50(7):1562–1570
https://doi.org/10.2337/diabetes.50.7.1562
Published: 01 July 2001
View article titled, Glucagon-Like Peptide-1 and Exendin-4 Stimulate β-Cell Neogenesis in Streptozotocin-Treated Newborn Rats Resulting in Persistently Improved Glucose Homeostasis at Adult Age
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Journal Articles

Insulin Administration Enhances Growth of the β-Cell Mass in Streptozotocin-Treated Newborn Rats

Jamileh Movassat, Catherine Saulnier, Bernard Portha
Journal: Diabetes
Diabetes 1997;46(9):1445–1452
https://doi.org/10.2337/diab.46.9.1445
Published: 01 September 1997
View article titled, Insulin Administration Enhances Growth of the β-Cell Mass in Streptozotocin-Treated Newborn Rats
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Journal Articles

Benfluorex Normalizes Hyperglycemia and Reverses Hepatic Insulin Resistance in STZ-Induced Diabetic Rats

Patricia Serradas, Olivier Blondel, Danielle Bailbe, Bernard Portha
Journal: Diabetes
Diabetes 1993;42(4):564–570
https://doi.org/10.2337/diab.42.4.564
Published: 01 April 1993
View article titled, Benfluorex Normalizes Hyperglycemia and Reverses Hepatic Insulin Resistance in STZ-Induced Diabetic Rats
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Journal Articles

β-Cell Insensitivity to Glucose in the GK Rat, a Spontaneous Nonobese Model for Type II Diabetes

Bernard Portha, Patricia Serradas, Danielle Bailbé, Ken-Ichi Suzuki, Yoshio Goto, Marie-Hélène Giroix
Journal: Diabetes
Diabetes 1991;40(4):486–491
https://doi.org/10.2337/diab.40.4.486
Published: 01 April 1991
View article titled, β-Cell Insensitivity to Glucose in the GK Rat, a Spontaneous Nonobese Model for Type II Diabetes
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Journal Articles

Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal Streptozocin

Marie-Helene Giroix, Joanne Rasschaert, Danille Bailbe, Viviane Leclercq-Meyer, Abdullah Sener, Bernard Portha, Willy J Malaisse
Journal: Diabetes
Diabetes 1991;40(2):227–232
https://doi.org/10.2337/diab.40.2.227
Published: 01 February 1991
View article titled, Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal Streptozocin
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Journal Articles

Relation of Insulin Deficiency to Impaired Insulin Action in NIDDM Adult Rats Given Streptozocin as Neonates

Olivier Blondel, Daniele Bailbé, Bernard Portha
Journal: Diabetes
Diabetes 1989;38(5):610–617
https://doi.org/10.2337/diab.38.5.610
Published: 01 May 1989
View article titled, Relation of Insulin Deficiency to Impaired Insulin Action in NIDDM Adult Rats Given Streptozocin as Neonates
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Journal Articles

Insulin Production and Glucose Metabolism in Isolated Pancreatic Islets of Rats With NIDDM

Bernard Portha, Marie-Hélène Giroix, Patricia Serradas, Nils Welsh, Claes Hellerström, Abdullah Sener, Willy J Malaisse
Journal: Diabetes
Diabetes 1988;37(9):1226–1233
https://doi.org/10.2337/diab.37.9.1226
Published: 01 September 1988
View article titled, Insulin Production and Glucose Metabolism in Isolated Pancreatic Islets of Rats With NIDDM
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Journal Articles

Insulin Treatment Improves Glucose-Induced Insulin Release in Rats With NIDDM Induced by Streptozocin

Micheline Kergoat, Danielle Bailbe, Bernard Portha
Journal: Diabetes
Diabetes 1987;36(8):971–977
https://doi.org/10.2337/diab.36.8.971
Published: 01 August 1987
View article titled, Insulin Treatment Improves Glucose-Induced Insulin Release in Rats With NIDDM Induced by Streptozocin
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Journal Articles

In Vivo Hepatic and Peripheral Insulin Sensitivity in Rats with Non-insulin-dependent Diabetes Induced by Streptozocin: Assessment with the Insulin-Glucose Clamp Technique

Micheline Kergoat, Bernard Portha
Journal: Diabetes
Diabetes 1985;34(11):1120–1126
https://doi.org/10.2337/diab.34.11.1120
Published: 01 November 1985
View article titled, In Vivo Hepatic and Peripheral Insulin Sensitivity in Rats with Non-insulin-dependent Diabetes Induced by Streptozocin: Assessment with the Insulin-Glucose Clamp Technique
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Journal Articles

Dynamics of Glucose-induced Insulin Release During the Spontaneous Remission of Streptozocin Diabetes Induced in the Newborn Rat

Bernard Portha, Micheline Kergoat
Journal: Diabetes
Diabetes 1985;34(6):574–579
https://doi.org/10.2337/diab.34.6.574
Published: 01 June 1985
View article titled, Dynamics of Glucose-induced Insulin Release During the Spontaneous Remission of Streptozocin Diabetes Induced in the Newborn Rat
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Journal Articles

Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused Pancreas

Marie-Hélène Giroix, Bernard Portha, Micheline Kergoat, Danielle Bailbe, Luc Picon
Journal: Diabetes
Diabetes 1983;32(5):445–451
https://doi.org/10.2337/diab.32.5.445
Published: 01 May 1983
View article titled, Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused Pancreas
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Journal Articles

Insulin Treatment Improves the Spontaneous Remission of Neonatal Streptozotocin Diabetes in the Rat

Bernard Portha, Luc Picon
Journal: Diabetes
Diabetes 1982;31(2):165–169
https://doi.org/10.2337/diab.31.2.165
Published: 01 February 1982
View article titled, Insulin Treatment Improves the Spontaneous Remission of Neonatal Streptozotocin Diabetes in the Rat
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Journal Articles

Experimental Chemical Diabetes and Pregnancy in the Rat: Evolution of Glucose Tolerance and Insulin Response

Nicole Triadou, Bernard Portha, Luc Picon, Gabriel Rosselin
Journal: Diabetes
Diabetes 1982;31(1):75–79
https://doi.org/10.2337/diab.31.1.75
Published: 01 January 1982
View article titled, Experimental Chemical Diabetes and Pregnancy in the Rat: Evolution of Glucose Tolerance and Insulin Response
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Journal Articles

Glucocorticoid-induced Recovery from Streptozotocin Diabetes in the Adult Rat

Michel Roudier, Bernard Portha, Luc Picon
Journal: Diabetes
Diabetes 1980;29(3):201–205
https://doi.org/10.2337/diab.29.3.201
Published: 01 March 1980
View article titled, Glucocorticoid-induced Recovery from Streptozotocin Diabetes in the Adult Rat
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