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Betty A Maddux
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Journal Articles

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

Vinay Bhaskar, Ira D. Goldfine, Daniel H. Bedinger, Angela Lau, Hua F. Kuan, Lisa M. Gross, Masahisa Handa, Betty A. Maddux, Susan R. Watson, Shirley Zhu, Ajay J. Narasimha, Raphael Levy, Lynn Webster, Sujeewa D. Wijesuriya, Naichi Liu, Xiaorong Wu, David Chemla-Vogel, Catarina Tran, Steve R. Lee, Steve Wong, Diane Wilcock, Mark L. White, John A. Corbin
Journal: Diabetes
Diabetes 2012;61(5):1263–1271
https://doi.org/10.2337/db11-1578
Published: 13 April 2012
View article titled, A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control
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Journal Articles

Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance

Hengjiang Dong, Betty A. Maddux, Jennifer Altomonte, Marcia Meseck, Domenico Accili, Robert Terkeltaub, Kristen Johnson, Jack F. Youngren, Ira D. Goldfine
Journal: Diabetes
Diabetes 2005;54(2):367–372
https://doi.org/10.2337/diabetes.54.2.367
Published: 01 February 2005
View article titled, Increased Hepatic Levels of the Insulin Receptor Inhibitor, PC-1/NPP1, Induce Insulin Resistance and Glucose Intolerance
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Journal Articles

Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?

Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux, Gerold M. Grodsky
Journal: Diabetes
Diabetes 2003;52(1):1–8
https://doi.org/10.2337/diabetes.52.1.1
Published: 01 January 2003
View article titled, Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?
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Journal Articles

Small Molecule Insulin Receptor Activators Potentiate Insulin Action in Insulin-Resistant Cells

Ming Li, Jack F. Youngren, Vara Prasad Manchem, Michael Kozlowski, Bei B. Zhang, Betty A. Maddux, Ira D. Goldfine
Journal: Diabetes
Diabetes 2001;50(10):2323–2328
https://doi.org/10.2337/diabetes.50.10.2323
Published: 01 October 2001
View article titled, Small Molecule Insulin Receptor Activators Potentiate Insulin Action in Insulin-Resistant Cells
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Journal Articles

Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid

Betty A. Maddux, Wendy See, John C. Lawrence, Jr., Amy L. Goldfine, Ira D. Goldfine, Joseph L. Evans
Journal: Diabetes
Diabetes 2001;50(2):404–410
https://doi.org/10.2337/diabetes.50.2.404
Published: 01 February 2001
View article titled, Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid
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Journal Articles

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

Jack F Youngren, Betty A Maddux, Shlomo Sasson, Paolo Sbraccia, Edward B Tapscott, Melvin S Swanson, G Lynis Dohm, Ira D Goldfine
Journal: Diabetes
Diabetes 1996;45(10):1324–1328
https://doi.org/10.2337/diab.45.10.1324
Published: 01 October 1996
View article titled, Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport
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Journal Articles

Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM

Paolo Sbraccia, Patricia A Goodman, Betty A Maddux, K Y Wong, Y-D I Chen, Gerald M Reaven, Ira D Goldfine
Journal: Diabetes
Diabetes 1991;40(2):295–299
https://doi.org/10.2337/diab.40.2.295
Published: 01 February 1991
View article titled, Production of Inhibitor of Insulin-Receptor Tyrosine Kinase in Fibroblasts From Patient With Insulin Resistance and NIDDM
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Journal Articles

Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels

Yoshinori Okabayashi, Betty A Maddux, Alexander R McDonald, Craig D Logsdon, John A Williams, Ira D Goldfine
Journal: Diabetes
Diabetes 1989;38(2):182–187
https://doi.org/10.2337/diab.38.2.182
Published: 01 February 1989
View article titled, Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels
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Journal Articles

Sequence and Analysis of Promoter Region of Human Insulin-Receptor Gene

Paul W Mamula, Kwok-Ying Wong, Betty A Maddux, Alexander R McDonald, Ira D Goldfine
Journal: Diabetes
Diabetes 1988;37(9):1241–1246
https://doi.org/10.2337/diab.37.9.1241
Published: 01 September 1988
View article titled, Sequence and Analysis of Promoter Region of Human Insulin-Receptor Gene
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Journal Articles

Regulation of Insulin-Receptor mRNA Levels by Glucocorticoids

Alex R McDonald, Betty A Maddux, Y Okabayashi, K Y Wong, D M Hawley, Craig D Logsdon, Ira D Goldfine
Journal: Diabetes
Diabetes 1987;36(6):779–781
https://doi.org/10.2337/diab.36.6.779
Published: 01 June 1987
View article titled, Regulation of Insulin-Receptor mRNA Levels by Glucocorticoids
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Journal Articles

Tissue-specific Antibodies Against the Fibroblast Insulin Receptor in a Patient with Lupus Nephritis and Hypoglycemia

Roberto De Pirro, Patrizia Borboni, Renato Lauro, Antonella Festa, Ivano Testa, Carlo De Martinis, Betty A Maddux, Ira D Goldfine
Journal: Diabetes
Diabetes 1985;34(11):1088–1091
https://doi.org/10.2337/diab.34.11.1088
Published: 01 November 1985
View article titled, Tissue-specific Antibodies Against the Fibroblast Insulin Receptor in a Patient with Lupus Nephritis and Hypoglycemia
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