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Brian Rodrigues
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Journal Articles

Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction

Available to Purchase
Chae Syng Lee, Rui Shang, Fulong Wang, Parisa Khayambashi, Hualin Wang, Gala Araujo, Karanjit Puri, Israel Vlodavsky, Bahira Hussein, Brian Rodrigues
Journal: Diabetes
Diabetes 2024;73(8):1300–1316
https://doi.org/10.2337/db24-0217
Published: 21 May 2024
View articletitled, Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction
Open the PDF for Heparanase Stimulation of Physiologic Cardiac Hypertrophy Is Suppressed After Chronic Diabetes, Resulting in Cardiac Remodeling and Dysfunction in another window
Meeting Abstracts

23-OR: Reduction in Insulin Uncovers a Novel Effect of VEGFB on Cardiac Substrate Utilization

Free
RUI SHANG, CHAE SYNG LEE, BAHIRA HUSSEIN, BRIAN RODRIGUES
Journal: Diabetes
Diabetes 2023;72(Supplement_1):23-OR
https://doi.org/10.2337/db23-23-OR
Published: 20 June 2023
View articletitled, 23-OR: Reduction in Insulin Uncovers a Novel Effect of VEGFB on Cardiac Substrate Utilization
Meeting Abstracts

24-OR: Augmented Heparanase Secretion in Diabetes Regulates Development of Cardiac Hypertrophy

Free
CHAE SYNG LEE, RUI SHANG, BAHIRA HUSSEIN, BRIAN RODRIGUES
Journal: Diabetes
Diabetes 2023;72(Supplement_1):24-OR
https://doi.org/10.2337/db23-24-OR
Published: 20 June 2023
View articletitled, 24-OR: Augmented Heparanase Secretion in Diabetes Regulates Development of Cardiac Hypertrophy
Journal Articles

Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes

Free
Dahai Zhang, Fulong Wang, Nathaniel Lal, Amy Pei-Ling Chiu, Andrea Wan, Jocelyn Jia, Denise Bierende, Stephane Flibotte, Sunita Sinha, Ali Asadi, Xiaoke Hu, Farnaz Taghizadeh, Thomas Pulinilkunnil, Corey Nislow, Israel Vlodavsky, James D. Johnson, Timothy J. Kieffer, Bahira Hussein, Brian Rodrigues
Journal: Diabetes
Diabetes 2017;66(1):45–57
https://doi.org/10.2337/db16-0761
Published: 07 October 2016
View articletitled, Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes
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Includes: Supplementary data
Journal Articles

Endothelial Cell Heparanase Taken Up by Cardiomyocytes Regulates Lipoprotein Lipase Transfer to the Coronary Lumen After Diabetes

Free
Ying Wang, Amy Pei-Ling Chiu, Katharina Neumaier, Fulong Wang, Dahai Zhang, Bahira Hussein, Nathaniel Lal, Andrea Wan, George Liu, Israel Vlodavsky, Brian Rodrigues
Journal: Diabetes
Diabetes 2014;63(8):2643–2655
https://doi.org/10.2337/db13-1842
Published: 17 July 2014
View articletitled, Endothelial Cell Heparanase Taken Up by Cardiomyocytes Regulates Lipoprotein Lipase Transfer to the Coronary Lumen After Diabetes
Open the PDF for Endothelial Cell Heparanase Taken Up by Cardiomyocytes Regulates Lipoprotein Lipase Transfer to the Coronary Lumen After Diabetes in another window
Includes: Supplementary data
Journal Articles

Hyperglycemia-Induced Protein Kinase C β2 Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling

Open Access
Shaoqing Lei, Haobo Li, Jinjin Xu, Yanan Liu, Xia Gao, Junwen Wang, Kwok F.J. Ng, Wayne Bond Lau, Xin-liang Ma, Brian Rodrigues, Michael G. Irwin, Zhengyuan Xia
Journal: Diabetes
Diabetes 2013;62(7):2318–2328
https://doi.org/10.2337/db12-1391
Published: 14 June 2013
View articletitled, Hyperglycemia-Induced Protein Kinase C β2 Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling
Open the PDF for Hyperglycemia-Induced Protein Kinase C β2 Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling in another window
Journal Articles

Severity of Diabetes Governs Vascular Lipoprotein Lipase by Affecting Enzyme Dimerization and Disassembly

Open Access
Ying Wang, Prasanth Puthanveetil, Fang Wang, Min Suk Kim, Ashraf Abrahani, Brian Rodrigues
Journal: Diabetes
Diabetes 2011;60(8):2041–2050
https://doi.org/10.2337/db11-0042
Published: 18 July 2011
View articletitled, Severity of Diabetes Governs Vascular Lipoprotein Lipase by Affecting Enzyme Dimerization and Disassembly
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Includes: Supplementary data
Journal Articles

Cleavage of Protein Kinase D After Acute Hypoinsulinemia Prevents Excessive Lipoprotein Lipase–Mediated Cardiac Triglyceride Accumulation

Open Access
Min Suk Kim, Fang Wang, Prasanth Puthanveetil, Girish Kewalramani, Sheila Innis, Lucy Marzban, Susan F. Steinberg, Travis D. Webber, Timothy J. Kieffer, Ashraf Abrahani, Brian Rodrigues
Journal: Diabetes
Diabetes 2009;58(11):2464–2475
https://doi.org/10.2337/db09-0681
Published: 01 November 2009
View articletitled, Cleavage of Protein Kinase D After Acute Hypoinsulinemia Prevents Excessive Lipoprotein Lipase–Mediated Cardiac Triglyceride Accumulation
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Includes: Supplementary data
Journal Articles

Acute Diabetes Moderates Trafficking of Cardiac Lipoprotein Lipase Through p38 Mitogen-Activated Protein Kinase–Dependent Actin Cytoskeleton Organization

Free
Min Suk Kim, Girish Kewalramani, Prasanth Puthanveetil, Vivian Lee, Ujendra Kumar, Ding An, Ashraf Abrahani, Brian Rodrigues
Journal: Diabetes
Diabetes 2008;57(1):64–76
https://doi.org/10.2337/db07-0832
Published: 01 January 2008
View articletitled, Acute Diabetes Moderates Trafficking of Cardiac Lipoprotein Lipase Through p38 Mitogen-Activated Protein Kinase–Dependent Actin Cytoskeleton Organization
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Journal Articles

Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism

Free
Dake Qi, Thomas Pulinilkunnil, Ding An, Sanjoy Ghosh, Ashraf Abrahani, John Andrew Pospisilik, Roger Brownsey, Rich Wambolt, Michael Allard, Brian Rodrigues
Journal: Diabetes
Diabetes 2004;53(7):1790–1797
https://doi.org/10.2337/diabetes.53.7.1790
Published: 01 July 2004
View articletitled, Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism
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Journal Articles

Differential Effects of Streptozotocin-Induced Diabetes on Cardiac Lipoprotein Lipase Activity

Free
Brian Rodrigues, Margaret C Cam, Kong Jian, Fiona Lim, Nandakumar Sambandam, Greg Shepherd
Journal: Diabetes
Diabetes 1997;46(8):1346–1353
https://doi.org/10.2337/diab.46.8.1346
Published: 01 August 1997
View articletitled, Differential Effects of Streptozotocin-Induced Diabetes on Cardiac Lipoprotein Lipase Activity
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Journal Articles

Effect of L-Carnitine Treatment on Lipid Metabolism and Cardiac Performance in Chronically Diabetic Rats

Free
Brian Rodrigues, Hong Xiang, John H McNeill
Journal: Diabetes
Diabetes 1988;37(10):1358–1364
https://doi.org/10.2337/diab.37.10.1358
Published: 01 October 1988
View articletitled, Effect of L-Carnitine Treatment on Lipid Metabolism and Cardiac Performance in Chronically Diabetic Rats
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