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Carlos Diéguez
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Journal Articles

MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance

Omar Al-Massadi, Mar Quiñones, Jerome Clasadonte, René Hernandez-Bautista, Amparo Romero-Picó, Cintia Folgueira, Donald A. Morgan, Imre Kalló, Violeta Heras, Ana Senra, Samuel C. Funderburk, Michael J. Krashes, Yara Souto, Miguel Fidalgo, Serge Luquet, Melissa J. Chee, Monica Imbernon, Daniel Beiroa, Lucía García-Caballero, Rosalia Gallego, Brian Y.H. Lam, Giles Yeo, Miguel Lopez, Zsolt Liposits, Kamal Rahmouni, Vincent Prevot, Carlos Dieguez, Ruben Nogueiras
Journal: Diabetes
Diabetes 2019;68(12):2210–2222
https://doi.org/10.2337/db19-0029
Published: 16 September 2019
View article titled, MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance
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Includes: Supplementary data
Journal Articles

SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity

Patricia Seoane-Collazo, Juan Roa, Eva Rial-Pensado, Laura Liñares-Pose, Daniel Beiroa, Francisco Ruíz-Pino, Tania López-González, Donald A. Morgan, José Ángel Pardavila, María Jesús Sánchez-Tapia, Noelia Martínez-Sánchez, Cristina Contreras, Miguel Fidalgo, Carlos Diéguez, Roberto Coppari, Kamal Rahmouni, Rubén Nogueiras, Manuel Tena-Sempere, Miguel López
Journal: Diabetes
Diabetes 2018;67(11):2213–2226
https://doi.org/10.2337/db17-1538
Published: 13 August 2018
View article titled, SF1-Specific AMPKα1 Deletion Protects Against Diet-Induced Obesity
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Includes: Supplementary data
Journal Articles

Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity

Cristina Contreras, Ismael González-García, Patricia Seoane-Collazo, Noelia Martínez-Sánchez, Laura Liñares-Pose, Eva Rial-Pensado, Johan Fernø, Manuel Tena-Sempere, Núria Casals, Carlos Diéguez, Rubén Nogueiras, Miguel López
Journal: Diabetes
Diabetes 2017;66(1):87–99
https://doi.org/10.2337/db15-1547
Published: 15 September 2016
View article titled, Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity
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Includes: Supplementary data
Journal Articles

Uroguanylin Action in the Brain Reduces Weight Gain in Obese Mice via Different Efferent Autonomic Pathways

Cintia Folgueira, Daniel Beiroa, Aurelie Callon, Omar Al-Massadi, Silvia Barja-Fernandez, Ana Senra, Johan Fernø, Miguel López, Carlos Dieguez, Felipe F. Casanueva, Françoise Rohner-Jeanrenaud, Luisa M. Seoane, Ruben Nogueiras
Journal: Diabetes
Diabetes 2016;65(2):421–432
https://doi.org/10.2337/db15-0889
Published: 13 November 2015
View article titled, Uroguanylin Action in the Brain Reduces Weight Gain in Obese Mice via Different Efferent Autonomic Pathways
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Includes: Supplementary data
Journal Articles

GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK

Daniel Beiroa, Monica Imbernon, Rosalía Gallego, Ana Senra, Daniel Herranz, Francesc Villarroya, Manuel Serrano, Johan Fernø, Javier Salvador, Javier Escalada, Carlos Dieguez, Miguel Lopez, Gema Frühbeck, Ruben Nogueiras
Journal: Diabetes
Diabetes 2014;63(10):3346–3358
https://doi.org/10.2337/db14-0302
Published: 15 September 2014
View article titled, GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK
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Includes: Supplementary data
Journal Articles

Hypothalamic Ceramide Levels Regulated by CPT1C Mediate the Orexigenic Effect of Ghrelin

Sara Ramírez, Luís Martins, Jordi Jacas, Patricia Carrasco, Macarena Pozo, Josep Clotet, Dolors Serra, Fausto G. Hegardt, Carlos Diéguez, Miguel López, Núria Casals
Journal: Diabetes
Diabetes 2013;62(7):2329–2337
https://doi.org/10.2337/db12-1451
Published: 14 June 2013
View article titled, Hypothalamic Ceramide Levels Regulated by CPT1C Mediate the Orexigenic Effect of Ghrelin
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Journal Articles

Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase

Pablo B. Martínez de Morentin, Andrew J. Whittle, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, Antonio Vidal-Puig, Miguel López
Journal: Diabetes
Diabetes 2012;61(4):807–817
https://doi.org/10.2337/db11-1079
Published: 14 March 2012
View article titled, Nicotine Induces Negative Energy Balance Through Hypothalamic AMP-Activated Protein Kinase
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Includes: Supplementary data
Journal Articles

The l-α-Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

José María Moreno-Navarrete, Victoria Catalán, Lauren Whyte, Adenis Díaz-Arteaga, Rafael Vázquez-Martínez, Fernando Rotellar, Rocío Guzmán, Javier Gómez-Ambrosi, Marina R. Pulido, Wendy R. Russell, Mónica Imbernón, Ruth A. Ross, María M. Malagón, Carlos Dieguez, José Manuel Fernández-Real, Gema Frühbeck, Ruben Nogueiras
Journal: Diabetes
Diabetes 2012;61(2):281–291
https://doi.org/10.2337/db11-0649
Published: 17 January 2012
View article titled, The <sc>l</sc>-α-Lysophosphatidylinositol/<em>GPR55</em> System and Its Potential Role in Human Obesity
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Includes: Supplementary data
Journal Articles

The Central Sirtuin 1/p53 Pathway Is Essential for the Orexigenic Action of Ghrelin

Douglas A. Velásquez, Gloria Martínez, Amparo Romero, María J. Vázquez, Katia D. Boit, Iria G. Dopeso-Reyes, Miguel López, Anxo Vidal, Ruben Nogueiras, Carlos Diéguez
Journal: Diabetes
Diabetes 2011;60(4):1177–1185
https://doi.org/10.2337/db10-0802
Published: 22 March 2011
View article titled, The Central Sirtuin 1/p53 Pathway Is Essential for the Orexigenic Action of Ghrelin
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Includes: Supplementary data
Journal Articles

Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance

Jose Manuel Fernandez-Real, Javier A. Menendez, Jose Maria Moreno-Navarrete, Matthias Blüher, Alejandro Vazquez-Martin, María Jesús Vázquez, Francisco Ortega, Carlos Diéguez, Gema Frühbeck, Wifredo Ricart, Antonio Vidal-Puig
Journal: Diabetes
Diabetes 2010;59(6):1506–1511
https://doi.org/10.2337/db09-1756
Published: 18 March 2010
View article titled, Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance
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Includes: Supplementary data
Journal Articles

Expression of Hypothalamic KiSS-1 System and Rescue of Defective Gonadotropic Responses by Kisspeptin in Streptozotocin-Induced Diabetic Male Rats

Juan M. Castellano, Victor M. Navarro, Rafael Fernández-Fernández, Juan Roa, Eva Vigo, Rafael Pineda, Carlos Dieguez, Enrique Aguilar, Leonor Pinilla, Manuel Tena-Sempere
Journal: Diabetes
Diabetes 2006;55(9):2602–2610
https://doi.org/10.2337/db05-1584
Published: 01 September 2006
View article titled, Expression of Hypothalamic KiSS-1 System and Rescue of Defective Gonadotropic Responses by Kisspeptin in Streptozotocin-Induced Diabetic Male Rats
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Journal Articles

Regulation of Growth Hormone Secretagogue Receptor Gene Expression in the Arcuate Nuclei of the Rat by Leptin and Ghrelin

Ruben Nogueiras, Sulay Tovar, Sharon E. Mitchell, D. Vernon Rayner, Zoe A. Archer, Carlos Dieguez, Lynda M. Williams
Journal: Diabetes
Diabetes 2004;53(10):2552–2558
https://doi.org/10.2337/diabetes.53.10.2552
Published: 01 October 2004
View article titled, Regulation of Growth Hormone Secretagogue Receptor Gene Expression in the Arcuate Nuclei of the Rat by Leptin and Ghrelin
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